Opioid site in nucleus accumbens shell mediates eating and hedonic 'liking' for food: Map based on microinjection Fos plumes

Brain Research

Volumn 863, Issue 1-2, 2000, Pages 71-86

  Peciña, Susana ^a   Berridge, Kent C ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Addiction; Agonist; Antagonist; Appetite; Core; Dopamine; Food intake; Genes (fos); Hedonic; Hyperphagia; Mesolimbic; Morphine; Motivation; Naloxone; Nucleus accumbens; Opiate; Opioid; Palatability; Pleasure; Reward; Shell; Striatum; Transcription factors

Indexed keywords

MORPHINE; NALOXONE; OPIATE RECEPTOR; PROTEIN C FOS;

ANIMAL EXPERIMENT; APPETITE; CONTROLLED STUDY; CORPUS STRIATUM; FEEDING BEHAVIOR; FOOD INTAKE; GENE EXPRESSION; HYPERPHAGIA; IMMUNOREACTIVITY; INGESTION; MALE; MOTIVATION; NONHUMAN; NUCLEUS ACCUMBENS; PALATABILITY; PRIORITY JOURNAL; RAT; REVIEW;

EID: 0034725002     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02102-8     Document Type: Article

References (88)

1. H. Akil, C. Owens, H. Gutstein, L. Taylor, E. Curran, S. Watson, Endogenous opioids: overview and current issues, Drug Alcohol Depend. 51 (1998) 127-140.
2. G.F. Alheid, L. Heimer, New perspectives in basal forebrain organization of special relevance for neuropsychiatrie disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata, Neuroscience 27 (1988) 1-39.
3. V.P. Bakshi, A.E. Kelley, Feeding induced by opioid stimulation of the ventral striatum: role of opiate receptor subtypes, J. Pharmacol. Exp. Ther. 265 (1993) 1253-1260.
4. V.P. Bakshi, A.E. Kelley, Striatal regulation of morphine-induced hyperphagia - an anatomical mapping study, Psychopharmacology 111 (1993) 207-214.
5. V.P. Bakshi, A.E. Kelley, Sensitization and conditioning of feeding following multiple morphine microinjections into the nucleus accumbens, Brain Res. 648 (1994) 342-346.
6. K.C. Berridge, Food reward: brain substrates of wanting and liking, Neurosci. Biobehav. Rev. 20 (1996) 1-25.
7. K.C. Berridge, Taste reactivity: measuring hedonic impact in human infants and animals, Neurosci. Biobehav. Rev. 24 (2000) 173-198.
8. K.C. Berridge, S. Pecina, Benzodiazepines, appetite, and taste payability, Neurosci. Biobehav. Rev. 19 (1995) 121-131.
9. K.C. Berridge, T.E. Robinson, What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?, Brain Res. - Brain Res. Rev. 28 (1998) 309-369.
10. M. Bertino, G.K. Beauchamp, K. Engelman, Naltrexone, an opioid blocker, alters taste perception and nutrient intake in humans, Am. J. Physiol. 261 (1991) R59-63.
11. R.J. Bodnar, M.J. Glass, A. Ragnauth, M.L. Cooper, General, mu and kappa-opioid antagonists in the nucleus-accumbens alter food-intake under deprivation, glucoprivic and palatable conditions, Brain Res. 700 (1995) 205-212.
12. J.S. Brog, A. Salyapongse, A.Y. Deutch, D.S. Zahm, The patterns of afferent innervation of the core and shell in the 'accumbens' part of the rat ventral striatum: immunohistochemical detection of retrogradely transported fluoro-gold, J. Comp. Neurol. 338 (1993) 255-278.
13. W.A. Carlezon Jr., D.P. Devine, R.A. Wise, Habit-forming actions of nomifensine in nucleus accumbens, Psychopharmacology 122 (1995) 194-197.
14. W.A. Carlezon Jr., R.A. Wise, Microinjections of phencyclidine (PCP) and related drugs into nucleus accumbens shell potentiate medial forebrain bundle brain stimulation reward, Psychopharmacology 128 (1996) 413-420.
15. W.A. Carlezon Jr., R.A. Wise, Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex, J. Neurosci. 16 (1996) 3112-3122.
16. A. Chaudhuri, Neural activity mapping with inducible transcription factors, Neuroreport 8 (1997) v-ix.
17. K. Chergui, G.G. Nomikos, J.M. Mathe, F. Gonon, T.H. Svensson, Burst stimulation of the medial forebrain bundle selectively increase Fos-like immunoreactivity in the limbic forebrain of the rat, Neuroscience 72 (1996) 141-156.
18. L. Churchill, P.W. Kalivas, A topographically organized gammaaminobutyric acid projection from the ventral pallidum to the nucleus accumbens in the rat, J. Comp. Neurol. 345 (1994) 579-595.
19. S.N. Clarke, L.A. Parker, Morphine-induced modification of quinine palatability: effects of multiple morphine-quinine trials, Pharmacol. Biochem. Behav. 51 (1995) 505-508.
20. J. Cleary, D.T. Weldon, E. O'Hare, C. Billington, A.S. Levine, Naloxone effects on sucrose-motivated behavior, Psychopharmacol. (Berl) 126 (1996) 110-114.
21. S.J. Cooper, S. Higgs, Neuropharmacology of appetite and taste preferences, in: C.R. Legg, D.A. Booth (Eds.), Appetite: Neural and Behavioural Bases, Oxford University Press, New York, 1994, pp. 212-242.
22. S.J. Cooper, T.C. Kirkham, Opioid mechanisms in the control of food consumption and taste preferences, in: A.A. Herz, E.J. Simon (Eds.), Opioids, part I and II, Springer-Verlag, Berlin, 1993, pp. 239-262.
23. H.C. Cromwell, K.C. Berridge, Where does damage lead to enhanced food aversion: the ventral pallidum/substantia innominata or lateral hypothalamus?, Brain Res. 624 (1993) 1-10.
24. H.C. Cromwell, K.C. Berridge, Mapping of globus pallidus and ventral pallidum lesions that produce hyperkinetic treading, Brain Res. 668 (1994) 16-29.
25. T.G. Doyle, K.C. Berridge, B.A. Gosnell, Morphine enhances hedonic taste palatability in rats, Pharmacol. Biochem. Behav. 46 (1993) 745-749.
26. A. Drewnowski, D.D. Krahn, M.A. Demitrack, K. Nairn, B.A. Gosnell, Taste responses and preferences for sweet high-fat foods: evidence for opioid involvement, Physiol. Behav. 51 (1992) 371-379.
27. K.R. Evans, F.J. Vaccarino, Intra-nucleus accumbens amphetamine: dose-dependent effects on food intake, Pharmacol. Biochem. Behav. 25 (1986) 1149-1151.
28. K.R. Evans, F.J. Vaccarino, Amphetamine- and morphine-induced feeding: evidence for involvement of reward mechanisms, Neurosci. Biobehav. Rev. 14 (1990) 9-22.
29. M. Fantino, Opiaces endogenes, palatabilite et controle de la prise alimentaire, Ann. d'Endocrinol. 49 (1988) 125-132.
30. M. Fantino, J. Hosotte, M. Apfelbaum, An opioid antagonist, naltrexone, reduces preference for sucrose in humans, Am. J. Physiol. 251 (1986) R91-96.
31. S.Q. Giraudo, M.K. Grace, C.C.Welch, C.J. Billington, A.S. Levine, Naloxone's anorectic effect is dependent upon the relative palatability of food, Pharmacol. Biochem. Behav. 46 (1993) 917-921.
32. B.A. Gosnell, Central structures involved in opioid-induced feeding, Fed. Proc. 46 (1987) 163-167.
33. B.A. Gosnell, Involvement of mu opioid receptors in the amygdala in the control of feeding, Neuropharmacology 27 (1988) 319-326.
34. B.A. Gosnell, M.J. Majchrzak, Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats, Pharmacol. Biochem. Behav. 33 (1989) 805-810.
35. K.N. Gracy, A.L. Svingos,V.M. Pickel, Dual ultrastructural localization of mu-opioid receptors and NMDA-type glutamate receptors in the shell of the rat nucleus accumbens, J. Neurosci. 17 (1997) 4839-4848.
36. H.J. Grill, K.C. Berridge, Taste reactivity as a measure of the neural control of palatability, in: J.M. Sprague, A.N. Epstein (Eds.), Progress in Psychobiology and Physiological Psychology, Vol. 11, Academic Press, Orlando, 1985, pp. 1-61.
37. H.J. Grill, A.B. Ginsberg, R.J. Seeley, J.M. Kaplan, Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight, J. Neurosci. 18 (1998) 10128-10135.
38. H.J. Grill, R. Norgren, The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats, Brain Res. 143 (1978) 263-279.
39. HJ. Groenewegen, H.W. Berendse, S.N. Haber, Organization of the output of the ventral striatopallidal system in the rat: ventral pallidal efferents, Neuroscience 57 (1993) 113-142.
40. H.J. Gundersen, P. Bagger, T.F. Bendtsen et al., The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis, APMIS 96 (1988) 857-881.
41. L. Heimer, R.E. Harlan, G.F. Alheid, M.M. Garcia, J. de Olmos, Substantia innominata: a notion which impedes clinical-anatomical correlations in neuropsychiatrie disorders, Neuroscience 76 (1997) 957-1006.
42. L. Heimer, D.S. Zahm, L. Churchill, P.W. Kalivas, C. Wohltmann, Specificity in the projection patterns of accumbal core and shell in the rat, Neuroscience 41 (1991) 89-125.
43. T. Herdegen, J.D. Leah, Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins, Brain Res. Brain Res. Rev. 28 (1998) 370-490.
44. D.G. Herrera, H.A. Robertson, Activation of c-fos in the brain, Prog. Neurobiol. 50 (1996) 83-107.
45. K.G. Hill, S.W. Kiefer, Naltrexone treatment increases the aversiveness of alcohol for outbred rats, Alcohol. Clin. Exp. Res. 21 (1997) 637-641.
46. B.C. Hoebel, P.V. Rada, G.P. Mark, E.N. Pothos, Neural systems for reinforcement and inhibition of behavior: relevance to eating, addiction, and depression, in: Well-being: the Foundations of Hedonic Psychology, Russell Sage Foundation, New York, NY, 1999, pp. 558-572.
47. S. Ikemoto, B.S. Glazier, J.M. Murphy, W.J. McBride, Role of dopamine D1 and D2 receptors in the nucleus accumbens in mediating reward, J. Neurosci. 17 (1997) 8580-8587.
48. P.I. Johnson, J.B. Goodman, R. Condon, J.R. Stellar, Reward shifts and motor responses following microinjections of opiate-specific agonists into either the core or shell of the nucleus accumbens, Psychopharmacology 120 (1995) 195-202.
49. P.I. Johnson, M.A. Parente, J.R. Stellar, NMDA-induced lesions of the nucleus accumbens or the ventral pallidum increase the rewarding efficacy of food to deprived rats, Brain Res. 722 (1996) 109-117.
50. P.I. Johnson, J.R. Stellar, A.D. Paul, Regional reward differences within the ventral pallidum are revealed by microinjections of a mu opiate receptor agonist, Neuropharmacology 32 (1993) 1305-1314.
51. A.E. Kelley, E.P. Bless, C.J. Swanson, Investigation of the effects of opiate antagonists infused into the nucleus accumbens on feeding and sucrose drinking in rats, J. Pharmacol. Exp. Ther. 278 (1996) 1499-1507.
52. A.E. Kelley, C.J. Swanson, Feeding induced by blockade of AMPA and kainate receptors within the ventral striatum: a microinfusion mapping study, Behav. Brain Res. 89 (1997) 107-113.
53. C.M. Kotz, C.J. Billington, A.S. Levine, Opioids in the nucleus of the solitary tract are involved in feeding in the rat, Am. J. Physiol. 272 (1997) R1028-1032.
54. A.S. Levine, C.J. Billington, Why do we eat? A neural systems approach, Annu. Rev. Nutr. 17 (1997) 597-619.
55. A.S. Levine, D.T. Weldon, M. Grace, J.P. Cleary, C.J. Billington, Naloxone blocks that portion of feeding driven by sweet taste in food-restricted rats, Am. J. Physiol.-Regul. Integrative Comp. Physiol. 37 (1995) R248-R252.
56. F.C. Liu, A.M. Graybiel, Spatiotemporal dynamics of CREB phosphorylation: transient versus sustained phosphorylation in the developing striatum, Neuron 17 (1996) 1133-1144.
57. J. Liu, J. Nickolenko, F.R. Sharp, Morphine induces c-fos and junB in striatum and nucleus accumbens via Dl and N-methyl-D-aspartate receptors, Proc. Natl. Acad. Sci. USA 91 (1994) 8537-8541.
58. N.H. Majeed, B. Przewlocka, K. Wedzony, R. Przewlocki, Stimulation of food intake following opioid microinjection into the nucleus accumbens septi in rats, Peptides 7 (1986) 711-716.
59. C.S. Maldonado-Irizarry, A.E. Kelley, Differential behavioral effects following microinjection of an NMDA antagonist into nucleus accumbens subregions, Psychopharmacol. (Berl) 116 (1994) 65-72.
60. C.S. Maldonado-Irizarry, C.J. Swanson, A.E. Kelley, Glutamate receptors in the nucleus accumbens shell control feeding behavior via the lateral hypothalamus, J. Neurosci. 15 (1995) 6779-6788.
61. A. Mansour, C.A. Fox, S. Burke, F. Meng, R.C. Thompson, H. Akil, S.J. Watson, Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study, J. Comp. Neurol. 350 (1994) 412-438.
62. A. Mansour, H. Khachaturian, M.E. Lewis, H. Akil, S.J. Watson, Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain, J. Neurosci. 7 (1987) 2445-2464.
63. G.E. Meredith, B. Blank, H.J. Groenewegen, The distribution and compartmental organization of the cholinergic neurons in nucleus accumbens of the rat, Neuroscience 31 (1989) 327-345.
64. G.E. Meredith, A. Pattiselanno, H.J. Groenewegen, S.N. Haber, Shell and core in monkey and human nucleus accumbens identified with antibodies to calbindin-D28k, J. Comp. Neurol. 365 (1996) 628-639.
65. P.J. Morgane, Alterations in feeding and drinking behavior of rats with lesions of the globus pallidi, Am. J. Physiol. 201 (1961) 420-428.
66. R.F. Mucha, S.D. Iversen, Increased food intake after opioid microinjections into nucleus accumbens and ventral tegmental area of rat, Brain Res. 397 (1986) 214-224.
67. WJ. Nauta, V.B. Domesick, Afferent and efferent relationships of the basal ganglia, Ciba Found. Symp. 107 (1984) 3-29.
68. R. Norgren, Gustatory system, in: G. Paxinos (Ed.), The Rat Nervous System, Academic Press, San Diego, 1995, pp. 751-771.
69. J. Panksepp, Affective Neuroscience: the Foundations of Human and Animal Emotions, Oxford University Press, Oxford, UK, 1998.
70. L.A. Parker, S. Maier, M. Rennie, J. Crebolder, Morphine- and naltrexone-induced modification of palatability: analysis by the taste reactivity test, Behav. Neurosci. 106 (1992) 999-1010.
71. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1996.
72. S. Pecina, K.C. Berridge, Central enhancement of taste pleasure by intraventricular morphine, Neurobiology 3 (1995) 269-280.
73. F. Rene, A. Muller, E. Jover, B. Kieffer, B. Koch, J.P. Loeffler, Melanocortin receptors and delta-opioid receptor mediate opposite signalling actions of POMC-derived peptides in CATH.a cells, Eur. J. Neurosci. 10 (1998) 1885-1894.
74. H.J. Rideout, L.A. Parker, Morphine enhancement of sucrose palatability: analysis by the taste reactivity test, Pharmacol. Biochem. Behav. 53 (1996) 731-734.
75. R.J. Seeley, M.W. Schwartz, Neuroendocrine regulation of food intake, Acta Paediatr. Suppl. 88 (1999) 58-61.
76. A.C. Spector, Gustatory function in the parabrachial nuclei: implications from lesion studies in rats, Rev. Neurosci. 6 (1995) 143-175.
77. B.G. Stanley, D. Lanthier, S.F. Leibowitz, Multiple brain sites sensitive to feeding stimulation by opioid agonists: a cannula mapping study, Pharmacol. Biochem. Behav. 31 (1989) 825-832.
78. J.E. Steiner, The gustofacial response: observation on normal and anencephalic newborn infants, Symp. Oral Sens. Percept. 4 (1973) 254-278.
79. T.R. Stratford, M.R. Holahan, A.E. Kelley, Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake, Neuroreport 8 (1997) 423-426.
80. T.R. Stratford, A.E. Kelley, GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior, J. Neurosci. 17 (1997) 4434-4440.
81. C.J. Swanson, S. Heath, T.R. Stratford, A.E. Kelley, Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat, Pharmacol. Biochem. Behav. 58 (1997) 933-945.
82. I. Usuda, K. Tanaka, T. Chiba, Efferent projections of the nucleus accumbens in the rat with special reference to subdivision of the nucleus: biotinylated dextran amine study, Brain Res. 797 (1998) 73-93.
83. C.I. Wright, A.V. Beijer, H.J. Groenewegen, Basal amygdaloid complex afferents to the rat nucleus accumbens are compartmentally organized, J. Neurosci. 16 (1996) 1877-1893.
84. M.R. Yeomans, R.W. Gray, Effects of naltrexone on food intake and changes in subjective appetite during eating: evidence for opioid involvement in the appetizer effect, Physiol. Behav. 62 (1997) 15-21.
85. M.R. Yeomans, P. Wright, H.A. Macleod, J.A. Critchley, Effects of nalmefene on feeding in humans. Dissociation of hunger and palatability, Psychopharmacology 100 (1990) 426-432.
86. M. Zhang, B.A. Gosnell, A.E. Kelley, Intake of high-fat food is selectively enhanced by mu opioid receptor stimulation within the nucleus accumbens, J. Pharmacol. Exp. Ther. 285 (1998) 908-914.
87. M. Zhang, A.E. Kelley, Opiate agonists microinjected into the nucleus accumbens enhance sucrose drinking in rats, Psychopharmacology 132 (1997) 350-360.
88. M. Zhang, A.E. Kelley, Enhanced intake of high fat food following striatal mu opioid stimulation: microinjection mapping and Fos expression, Neuroscience, in press.