-
1
-
-
80052716066
-
Chronic lymphocytic leukemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
ESMO Guidelines Working Group
-
Eichhorst B, Dreyling M, Robak T, Montserrat E and Hallek M; ESMO Guidelines Working Group: Chronic lymphocytic leukemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 22 (Suppl 6): vi50-vi54, 2011.
-
(2011)
Ann Oncol
, vol.22
, Issue.SUPPL. 6
-
-
Eichhorst, B.1
Dreyling, M.2
Robak, T.3
Montserrat, E.4
Hallek, M.5
-
2
-
-
46749134890
-
Trends in long-term survival of patients with chronic lymphocytic leukemia from the 1980s to the early 21st century
-
Brenner H, Gondos A and Pulte D: Trends in long-term survival of patients with chronic lymphocytic leukemia from the 1980s to the early 21st century. Blood 111: 4916-4921, 2008.
-
(2008)
Blood
, vol.111
, pp. 4916-4921
-
-
Brenner, H.1
Gondos, A.2
Pulte, D.3
-
3
-
-
79551641161
-
Potential new agents for chronic lymphocytic leukemia treatment
-
Kiliańska ZM and Rogalińska M: Potential new agents for chronic lymphocytic leukemia treatment. Anticancer Agents Med Chem 10: 666-682, 2010.
-
(2010)
Anticancer Agents Med Chem
, vol.10
, pp. 666-682
-
-
Kiliańska, Z.M.1
Rogalińska, M.2
-
4
-
-
0034667624
-
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
-
Burger JA, Tsukada N, Burger M, Zvaifler NJ, Dell'Aquila M and Kipps TJ: Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 96: 2655-2663, 2000.
-
(2000)
Blood
, vol.96
, pp. 2655-2663
-
-
Burger, J.A.1
Tsukada, N.2
Burger, M.3
Zvaifler, N.J.4
Dell'Aquila, M.5
Kipps, T.J.6
-
5
-
-
0037207525
-
1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin
-
DOI 10.1182/blood-2002-01-0189
-
Decker T, Hipp S, Ringshausen I, Bogner C, Oelsner M, Schneller F and Peschel C: Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood 101: 278-285, 2003. (Pubitemid 36025919)
-
(2003)
Blood
, vol.101
, Issue.1
, pp. 278-285
-
-
Decker, T.1
Hipp, S.2
Ringshausen, I.3
Bogner, C.4
Oelsner, M.5
Schneller, F.6
Peschel, C.7
-
6
-
-
77951709095
-
Pleiotropic effects of statins. Basic research and clinical perspectives
-
Zhou Q and Liao JK: Pleiotropic effects of statins. Basic research and clinical perspectives. Circ J 74: 818-826, 2010.
-
(2010)
Circ J
, vol.74
, pp. 818-826
-
-
Zhou, Q.1
Liao, J.K.2
-
7
-
-
84860710342
-
Statins and prostate cancer: Role of cholesterol inhibition vs. prevention of small GTP-binding proteins
-
Roy M, Kung HJ and Ghosh PM: Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins. Am J Cancer Res 1: 542-561, 2011.
-
(2011)
Am J Cancer Res
, vol.1
, pp. 542-561
-
-
Roy, M.1
Kung, H.J.2
Ghosh, P.M.3
-
8
-
-
0042235811
-
Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9
-
DOI 10.1016/S0301-472X(03)00192-9
-
Chapman-Shimshoni D, Yuklea M, Radnay J, Shapiro H and Lishner M: Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9. Exp Hematol 31: 779-783, 2003. (Pubitemid 37075970)
-
(2003)
Experimental Hematology
, vol.31
, Issue.9
, pp. 779-783
-
-
Chapman-Shimshoni, D.1
Yuklea, M.2
Radnay, J.3
Shapiro, H.4
Lishner, M.5
-
9
-
-
33745312505
-
Lipid-lowering drugs
-
Pahan K: Lipid-lowering drugs. Cell Mol Life Sci 63: 1165-1167, 2006.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1165-1167
-
-
Pahan, K.1
-
10
-
-
79960834633
-
Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts
-
Copajaa M, Venegasa D, Aránguiza P, et al: Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts. Toxicol Appl Pharmacol 255: 57-64, 2011.
-
(2011)
Toxicol Appl Pharmacol
, vol.255
, pp. 57-64
-
-
Copajaa, M.1
Venegasa, D.2
Aránguiza, P.3
-
11
-
-
0036239832
-
HMG-CoA reductase inhibitors and the malignant cell: The statin family of drugs as triggers of tumor-specific apoptosis
-
DOI 10.1038/sj/leu/2402476
-
Wong WW, Dimitroulakos J, Minden MD and Penn LZ: HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis. Leukemia 16: 508-519, 2002. (Pubitemid 34460459)
-
(2002)
Leukemia
, vol.16
, Issue.4
, pp. 508-519
-
-
Wong, W.W.-L.1
Dimitroulakos, J.2
Minden, M.D.3
Penn, L.Z.4
-
13
-
-
0036207642
-
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells
-
Agarwal B, Halmos B, Feoktistov AS, et al: Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells. Carcinogenesis 23: 521-528, 2002. (Pubitemid 34257633)
-
(2002)
Carcinogenesis
, vol.23
, Issue.3
, pp. 521-528
-
-
Agarwal, B.1
Halmos, B.2
Feoktistov, A.S.3
Protiva, P.4
Ramey, W.G.5
Chen, M.6
Pothoulakis, C.7
Lamont, J.T.8
Holt, P.R.9
-
14
-
-
0344629822
-
Protein Geranylgeranylation Is Critical for the Regulation of Survival and Proliferation of Lymphoma Tumor Cells
-
van de Donk NW, Schotte D, Kamphuis MM, van Marion AM, van Kessel B, Bloem AC and Lokhorst HM: Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells. Clin Cancer Res 9: 5735-5748, 2003. (Pubitemid 37499498)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.15
, pp. 5735-5748
-
-
Van De, D.N.W.C.J.1
Schotte, D.2
Kamphuis, M.M.J.3
Van Marion, A.M.W.4
Van Kessel, B.5
Bloem, A.C.6
Lokhorst, H.M.7
-
15
-
-
14344260532
-
The potential of statins as part of anti-cancer treatment
-
DOI 10.1016/j.ejca.2004.12.009
-
Sleiffer S, van der Gaast A, Planting AS, Stoter G and Verweij J: The potential of statins as part of anti-cancer treatment. Eur J Cancer 41: 516-522, 2005. (Pubitemid 40292731)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.4
, pp. 516-522
-
-
Sleijfer, S.1
Van Der, G.A.2
Planting, A.S.Th.3
Stoter, G.4
Verweij, J.5
-
16
-
-
16844372930
-
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
-
DOI 10.1172/JCI200519935
-
Zhuang L, Kim J, Adam RM, Solomon KR and Freeman MR: Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. J Clin Invest 115: 959-968, 2005. (Pubitemid 40489400)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.4
, pp. 959-968
-
-
Zhuang, L.1
Kim, J.2
Adam, R.M.3
Solomon, K.R.4
Freeman, M.R.5
-
17
-
-
0016740933
-
Clinical staging of chronic lymphocytic leukemia
-
Rai KR, Sawitsky A, Cronkite EP, Chanana AD, Levy RN and Pasternack BS: Clinical staging of chronic lymphocytic leukemia. Blood 46: 219-234, 1975.
-
(1975)
Blood
, vol.46
, pp. 219-234
-
-
Rai, K.R.1
Sawitsky, A.2
Cronkite, E.P.3
Chanana, A.D.4
Levy, R.N.5
Pasternack, B.S.6
-
18
-
-
39049189036
-
In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone
-
Kobylinska A, Bednarek J, Blonski JZ, Hanausek M, Walaszek Z, Robak T and Kilianska ZM: In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone. Oncol Rep 16: 1389-1395, 2006.
-
(2006)
Oncol Rep
, vol.16
, pp. 1389-1395
-
-
Kobylinska, A.1
Bednarek, J.2
Blonski, J.Z.3
Hanausek, M.4
Walaszek, Z.5
Robak, T.6
Kilianska, Z.M.7
-
19
-
-
0032830965
-
In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia
-
Bellosillo B, Villamor N, Colomer D, Pons G, Montserrat E and Gil J: In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia. Blood 94: 2836-2843, 1998.
-
(1998)
Blood
, vol.94
, pp. 2836-2843
-
-
Bellosillo, B.1
Villamor, N.2
Colomer, D.3
Pons, G.4
Montserrat, E.5
Gil, J.6
-
22
-
-
33847642110
-
1' peaks on DNA content histograms
-
DOI 10.1002/cyto.a.20357
-
Kajstura M, Halicka HD, Pryjma J and Darzynkiewicz Z: Discontinuous fragmentation of nuclear DNA during apoptosis revealed by discrete 'sub-G1' peaks on DNA content histograms. Cytometry A 71: 125-131, 2007. (Pubitemid 46355337)
-
(2007)
Cytometry Part A
, vol.71
, Issue.3
, pp. 125-131
-
-
Kajstura, M.1
Halicka, H.D.2
Pryjma, J.3
Darzynkiewicz, Z.4
-
23
-
-
17744399490
-
Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint
-
DOI 10.1038/sj.onc.1204008
-
Kim J-S, Pirnia F, Choi YH, et al: Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint. Oncogene 19: 6082-6090, 2000. (Pubitemid 32039383)
-
(2000)
Oncogene
, vol.19
, Issue.52
, pp. 6082-6090
-
-
Kim, J.-S.1
Pirnia, F.2
Choi, Y.H.3
Nguyen, P.M.4
Knepper, B.5
Tsokos, M.6
Schulte, T.W.7
Birrer, M.J.8
Blagosklonny, M.V.9
Schaefer, O.10
Mushinski, J.F.11
Trepel, J.B.12
-
24
-
-
77956969727
-
Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells
-
Podhorecka M, Halicka D, Klimek P, Kowal M, Chocholska S and Dmoszyńska A: Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells. Ann Hematol 89: 1115-1124, 2010.
-
(2010)
Ann Hematol
, vol.89
, pp. 1115-1124
-
-
Podhorecka, M.1
Halicka, D.2
Klimek, P.3
Kowal, M.4
Chocholska, S.5
Dmoszyńska, A.6
-
25
-
-
0038046166
-
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
-
DOI 10.1101/gad.1093903
-
Nijhawan D, Fang M, Traer E, Zhong Q, Gao W, Du F and Wang X: Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev 17: 1475-1486, 2003. (Pubitemid 36734705)
-
(2003)
Genes and Development
, vol.17
, Issue.12
, pp. 1475-1486
-
-
Nijhawan, D.1
Fang, M.2
Traer, E.3
Zhong, Q.4
Gao, W.5
Du, F.6
Wang, X.7
-
26
-
-
4544348358
-
Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia
-
DOI 10.1080/10428190410001723317
-
Johnston JB, Paul JT, Neufeld NJ, et al: Role of myeloid cell factor-1 (Mcl-1) in chronic lymphocytic leukemia. Leuk Lymphoma 45: 2017-2027, 2004. (Pubitemid 39232850)
-
(2004)
Leukemia and Lymphoma
, vol.45
, Issue.10
, pp. 2017-2027
-
-
Johnston, J.B.1
Paul, J.T.2
Neufeld, N.J.3
Haney, N.4
Kropp, D.M.5
Hu, X.6
Cheang, M.7
Gibson, S.B.8
-
27
-
-
4644229322
-
Determination of the in vivo effects of cladribine alone and its combination with cyclophosphamide or cyclophosphamide and mitoxantrone on Bax and Bcl-2 protein expression in B-CLL cells
-
Kobylinska A, Blonski JZ, Hanausek M, Walaszek Z, Robak T and Kilianska ZM: Determination of the in vivo effects of cladribine alone and its combination with cyclophosphamide or cyclophosphamide and mitoxantrone on Bax and Bcl-2 protein expression in B-CLL cells. Oncol Rep 11: 699-705, 2004.
-
(2004)
Oncol Rep
, vol.11
, pp. 699-705
-
-
Kobylinska, A.1
Blonski, J.Z.2
Hanausek, M.3
Walaszek, Z.4
Robak, T.5
Kilianska, Z.M.6
-
28
-
-
0347416908
-
Mcl-1 and Bcl-2/Bax Ratio Are Associated with Treatment Response but Not with Rai Stage in B-Cell Chronic Lymphocytic Leukemia
-
DOI 10.1002/ajh.10453
-
Saxena A, Viswanathan S, Moshynska O, Tandon P, Sankaran K and Sheridan DP: Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. Am J Hematol 75: 22-33, 2004. (Pubitemid 38040164)
-
(2004)
American Journal of Hematology
, vol.75
, Issue.1
, pp. 22-33
-
-
Saxena, A.1
Viswanathan, S.2
Moshynska, O.3
Tandon, P.4
Sankaran, K.5
Sheridan, D.P.6
-
29
-
-
47249152803
-
Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: A molecular signature of anergy
-
Muzio M, Apollonio B, Scielzo C, et al: Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy. Blood 112: 188-195, 2008.
-
(2008)
Blood
, vol.112
, pp. 188-195
-
-
Muzio, M.1
Apollonio, B.2
Scielzo, C.3
-
30
-
-
76049117295
-
Expression and prognostic significance of the inhibitor of apoptosis protein (IAP) family and its antagonists in chronic lymphocytic leukaemia
-
Grzybowska-Izydorczyk O, Cebula B, Robak T and Smolewski P: Expression and prognostic significance of the inhibitor of apoptosis protein (IAP) family and its antagonists in chronic lymphocytic leukaemia. Eur J Cancer 46: 800-810, 2010.
-
(2010)
Eur J Cancer
, vol.46
, pp. 800-810
-
-
Grzybowska-Izydorczyk, O.1
Cebula, B.2
Robak, T.3
Smolewski, P.4
-
31
-
-
38049132599
-
Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro
-
Salman H, Bergman M, Djaldetti M and Bessler H: Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro. Biomed Pharmacother 62: 41-45, 2008.
-
(2008)
Biomed Pharmacother
, vol.62
, pp. 41-45
-
-
Salman, H.1
Bergman, M.2
Djaldetti, M.3
Bessler, H.4
-
32
-
-
0029831619
-
Calcium-dependent, interleukin 1-converting enzyme inhibitor-insensitive degradation of lamin B1 and DNA fragmentation in isolated thymocyte nuclei
-
McConkey DJ: Calcium-dependent, interleukin 1-converting enzyme inhibitor-insensitive degradation of lamin B1 and DNA fragmentation in isolated thymocyte nuclei. J Biol Chem 271: 22398-22406, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 22398-22406
-
-
McConkey, D.J.1
-
33
-
-
0042837950
-
Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1
-
Garnier P, Ying W and Swanson RA: Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1. J Neurosci 23: 7967-7973, 2003. (Pubitemid 37082448)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.22
, pp. 7967-7973
-
-
Garnier, P.1
Ying, W.2
Swanson, R.A.3
-
35
-
-
0033606960
-
Kip1 mediates its antiapoptotic activity
-
Kip1 mediates its antiapoptotic activity. Oncogene 18: 4839-4847, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 4839-4847
-
-
Eymin, B.1
Sordet, O.2
Droin, N.3
-
36
-
-
69149093799
-
Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide
-
Zolnierczyk JD, Błoński JZ, Robak T, Kiliańska ZM and Wesierska-Gadek J: Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide. Ann NY Acad Sci 1171: 124-131, 2009.
-
(2009)
Ann NY Acad Sci
, vol.1171
, pp. 124-131
-
-
Zolnierczyk, J.D.1
Błoński, J.Z.2
Robak, T.3
Kiliańska, Z.M.4
Wesierska-Gadek, J.5
-
37
-
-
0037213368
-
The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
-
Borner C: The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 39: 615-647, 2003.
-
(2003)
Mol Immunol
, vol.39
, pp. 615-647
-
-
Borner, C.1
-
38
-
-
33846106906
-
Larger than life: Mitochondria and the Bcl-2 family
-
DOI 10.1016/j.leukres.2006.06.027, PII S014521260600261X
-
Skommer J, Wlodkowic D and Deptala A: Larger than life: mitochondria and the Bcl-2 family. Leuk Res 31: 277-286, 2007. (Pubitemid 46073182)
-
(2007)
Leukemia Research
, vol.31
, Issue.3
, pp. 277-286
-
-
Skommer, J.1
Wlodkowic, D.2
Deptala, A.3
-
39
-
-
84864031857
-
Statin and cancer: Current and future prospects
-
Osmak M: Statin and cancer: current and future prospects. Cancer Lett 324: 1-12, 2012.
-
(2012)
Cancer Lett
, vol.324
, pp. 1-12
-
-
Osmak, M.1
|