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Volumn 94, Issue 8, 1999, Pages 2836-2843

In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD5 ANTIGEN; CYCLOPHOSPHAMIDE; FLUDARABINE; MAFOSFAMIDE; MITOXANTRONE; PROTEIN P53;

EID: 0032830965     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.8.2836.420k35_2836_2843     Document Type: Article
Times cited : (173)

References (47)
  • 1
    • 0028822481 scopus 로고
    • Chronic lymphocytic leukemia
    • Rozman C, Montserrat E: Chronic lymphocytic leukemia. N Engl J Med 333:1052, 1995
    • (1995) N Engl J Med , vol.333 , pp. 1052
    • Rozman, C.1    Montserrat, E.2
  • 2
    • 0031890032 scopus 로고    scopus 로고
    • Molecular biology of chronic lymphocytic leukemia
    • Reed JC: Molecular biology of chronic lymphocytic leukemia. Semin Oncol 25:11, 1998
    • (1998) Semin Oncol , vol.25 , pp. 11
    • Reed, J.C.1
  • 3
    • 0030626129 scopus 로고    scopus 로고
    • Treatment of B-cell chronic lymphocytic leukemia: Current status and future perspectives
    • Montserrat E, Bosch F, Rozman C: Treatment of B-cell chronic lymphocytic leukemia: Current status and future perspectives. J Intern Med Suppl 242:63, 1997
    • (1997) J Intern Med Suppl , vol.242 , pp. 63
    • Montserrat, E.1    Bosch, F.2    Rozman, C.3
  • 6
    • 0027323550 scopus 로고
    • Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment
    • O'Brien S, Kantarjian H, Beran M, Smith T, Koller C, Estey E, Robertson LE, Lerner S, Keating M: Results of fludarabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood 82:1695, 1993
    • (1993) Blood , vol.82 , pp. 1695
    • O'Brien, S.1    Kantarjian, H.2    Beran, M.3    Smith, T.4    Koller, C.5    Estey, E.6    Robertson, L.E.7    Lerner, S.8    Keating, M.9
  • 7
    • 0029118503 scopus 로고
    • Purine nucleoside analogs: Emerging roles in indolent lymphoproliferative disorders
    • Tallman MS, Hakimian D: Purine nucleoside analogs: Emerging roles in indolent lymphoproliferative disorders. Blood 86:2463, 1995
    • (1995) Blood , vol.86 , pp. 2463
    • Tallman, M.S.1    Hakimian, D.2
  • 8
    • 0031867045 scopus 로고    scopus 로고
    • Therapy for previously untreated chronic lymphocytic leukemia: A reevaluation
    • Cheson BD: Therapy for previously untreated chronic lymphocytic leukemia: A reevaluation. Semin Hematol 35:14, 1998 (suppl 3)
    • (1998) Semin Hematol , vol.35 , Issue.3 SUPPL. , pp. 14
    • Cheson, B.D.1
  • 9
    • 0000431595 scopus 로고    scopus 로고
    • A randomized comparison of fludarabine and chlorambucil for patients with previously untreated chronic lymphocytic leukemia. A CALGB, SWOG, CTG/NCI-C and ECOG inter-group study
    • abstr
    • Rai KR, Peterson B, Elias L, Shepherd L, Hines J, Nelson D, Cheson B, Kolitz J, Schiffer CA: A randomized comparison of fludarabine and chlorambucil for patients with previously untreated chronic lymphocytic leukemia. A CALGB, SWOG, CTG/NCI-C and ECOG inter-group study. Blood 88:141a, 1996 (abstr, suppl 1)
    • (1996) Blood , vol.88 , Issue.1 SUPPL.
    • Rai, K.R.1    Peterson, B.2    Elias, L.3    Shepherd, L.4    Hines, J.5    Nelson, D.6    Cheson, B.7    Kolitz, J.8    Schiffer, C.A.9
  • 10
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, arid prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
    • French Cooperative Group on CLL, Johnson S, Smith AG, Loffler H, Osby E, Juliusson G, Emmerich B, Wyld PJ, Hiddemann W: Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, arid prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. Lancet 347:1432, 1996
    • (1996) Lancet , vol.347 , pp. 1432
    • Johnson, S.1    Smith, A.G.2    Loffler, H.3    Osby, E.4    Juliusson, G.5    Emmerich, B.6    Wyld, P.J.7    Hiddemann, W.8
  • 11
    • 0031841742 scopus 로고    scopus 로고
    • Clinical challenges in chronic lymphocytic leukemia
    • O'Brien S: Clinical challenges in chronic lymphocytic leukemia. Semin Hematol 35:22, 1998 (suppl 3)
    • (1998) Semin Hematol , vol.35 , Issue.3 SUPPL. , pp. 22
    • O'Brien, S.1
  • 12
    • 0029957407 scopus 로고    scopus 로고
    • Ennui or not ennui, that is the question
    • Cheson BD: Ennui or not ennui, that is the question. . . Ann Oncol 7:767, 1996
    • (1996) Ann Oncol , vol.7 , pp. 767
    • Cheson, B.D.1
  • 13
    • 0030973344 scopus 로고    scopus 로고
    • Fludarabine. An update of its pharmacology and use in the treatment of haematological malignancies
    • Adkins JC, Peters DH, Markham A: Fludarabine. An update of its pharmacology and use in the treatment of haematological malignancies. Drugs 53:1005, 1997
    • (1997) Drugs , vol.53 , pp. 1005
    • Adkins, J.C.1    Peters, D.H.2    Markham, A.3
  • 15
    • 0343399756 scopus 로고    scopus 로고
    • Fludarabine and cyclophosphamide as first therapy for indolent lymphoproliferative disorders: Response rates and toxicity
    • abstr
    • Flinn IW, Byrd JC, Seifter E, Marcellus D, Lee N, Diehl LF, Ambinder RF, Grever MR, Vogelsang G: Fludarabine and cyclophosphamide as first therapy for indolent lymphoproliferative disorders: response rates and toxicity. Blood 88:589a, 1996 (abstr, suppl 1)
    • (1996) Blood , vol.88 , Issue.1 SUPPL.
    • Flinn, I.W.1    Byrd, J.C.2    Seifter, E.3    Marcellus, D.4    Lee, N.5    Diehl, L.F.6    Ambinder, R.F.7    Grever, M.R.8    Vogelsang, G.9
  • 16
    • 0030733897 scopus 로고    scopus 로고
    • Combined therapy with fludarabine and cyclophosphamide in relapsed/ resistant patients with B-cell chronic lymphocytic leukaemia and non-Hodgkin's lymphomas
    • Zaja F, Rogato A, Russo D, Marin L, Silvestri F, Baccarani M: Combined therapy with fludarabine and cyclophosphamide in relapsed/ resistant patients with B-cell chronic lymphocytic leukaemia and non-Hodgkin's lymphomas. Eur J Haematol 59:327, 1997
    • (1997) Eur J Haematol , vol.59 , pp. 327
    • Zaja, F.1    Rogato, A.2    Russo, D.3    Marin, L.4    Silvestri, F.5    Baccarani, M.6
  • 18
    • 0028022841 scopus 로고
    • Concomitant administration of chlorambucil limits dose intensity of fludarabine in previously treated patients with chronic lymphocytic leukemia
    • Weiss M, Spiess T, Berman E, Kempin S: Concomitant administration of chlorambucil limits dose intensity of fludarabine in previously treated patients with chronic lymphocytic leukemia. Leukemia 8:1290, 1994
    • (1994) Leukemia , vol.8 , pp. 1290
    • Weiss, M.1    Spiess, T.2    Berman, E.3    Kempin, S.4
  • 19
    • 0003330368 scopus 로고    scopus 로고
    • Fludarabine, cyclophosphamide and mitoxantrone therapy in resistant or relapsed chronic lymphocytic leukemia or follicular lymphoma
    • abstr
    • Bosch F, Perales M, Cobo F, Esteve J, Rafel M, López-Guillermo A, Ribera JM, Campo E, Montserrat E: Fludarabine, cyclophosphamide and mitoxantrone therapy in resistant or relapsed chronic lymphocytic leukemia or follicular lymphoma. Blood 90:530a, 1997 (abstr, suppl 1)
    • (1997) Blood , vol.90 , Issue.1 SUPPL.
    • Bosch, F.1    Perales, M.2    Cobo, F.3    Esteve, J.4    Rafel, M.5    López-Guillermo, A.6    Ribera, J.M.7    Campo, E.8    Montserrat, E.9
  • 21
    • 0030905543 scopus 로고    scopus 로고
    • Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells
    • Bellosillo B, Dalmau M, Colomer D, Gil J: Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells. Blood 89:3378, 1997
    • (1997) Blood , vol.89 , pp. 3378
    • Bellosillo, B.1    Dalmau, M.2    Colomer, D.3    Gil, J.4
  • 22
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55, 1983
    • (1983) J Immunol Methods , vol.65 , pp. 55
    • Mosmann, T.1
  • 23
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271, 1991
    • (1991) J Immunol Methods , vol.139 , pp. 271
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 26
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957, 1993
    • (1993) Cell , vol.74 , pp. 957
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 27
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ: p53, the cellular gatekeeper for growth and division. Cell 88:323, 1997
    • (1997) Cell , vol.88 , pp. 323
    • Levine, A.J.1
  • 28
    • 0027436745 scopus 로고
    • p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
    • El Rouby S, Thomas A, Costin D, Rosenberg CR, Potmesil M, Silber R, Newcomb EW: p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression. Blood 82:3452, 1993
    • (1993) Blood , vol.82 , pp. 3452
    • El Rouby, S.1    Thomas, A.2    Costin, D.3    Rosenberg, C.R.4    Potmesil, M.5    Silber, R.6    Newcomb, E.W.7
  • 31
    • 0031829418 scopus 로고    scopus 로고
    • In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues-correlation with clinical course
    • Bromidge TJ, Turner DL, Howe DJ, Johnson SA, Rule SAJ: In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues-correlation with clinical course. Leukemia 12:1230, 1998
    • (1998) Leukemia , vol.12 , pp. 1230
    • Bromidge, T.J.1    Turner, D.L.2    Howe, D.J.3    Johnson, S.A.4    Rule, S.A.J.5
  • 33
    • 0027318216 scopus 로고
    • Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma
    • Frankfurt OS, Byrnes JJ, Seckinger D, Sugarbaker EV: Apoptosis (programmed cell death) and the evaluation of chemosensitivity in chronic lymphocytic leukemia and lymphoma. Oncol Res 5:37, 1993
    • (1993) Oncol Res , vol.5 , pp. 37
    • Frankfurt, O.S.1    Byrnes, J.J.2    Seckinger, D.3    Sugarbaker, E.V.4
  • 35
    • 0031982877 scopus 로고    scopus 로고
    • Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells
    • Bellosillo B, Colomer D, Pons G, Gil J: Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells. Br J Haematol 100:142, 1998
    • (1998) Br J Haematol , vol.100 , pp. 142
    • Bellosillo, B.1    Colomer, D.2    Pons, G.3    Gil, J.4
  • 36
    • 0031722842 scopus 로고    scopus 로고
    • Chlorambucil synergizes with purine analogs in inducing in vitro cytotoxicity in B-cell chronic lymphocytic leukemia
    • letter
    • Callea I, Console G, Sculli G, Filangeri M, Messina G, Morabito F: Chlorambucil synergizes with purine analogs in inducing in vitro cytotoxicity in B-cell chronic lymphocytic leukemia. Haematologica 83:756, 1998 (letter)
    • (1998) Haematologica , vol.83 , pp. 756
    • Callea, I.1    Console, G.2    Sculli, G.3    Filangeri, M.4    Messina, G.5    Morabito, F.6
  • 37
    • 0024578860 scopus 로고
    • Oxazaphosphorine cytostatics: Past-present-future. Seventh Cain Memorial Award lecture
    • Brock N: Oxazaphosphorine cytostatics: Past-present-future. Seventh Cain Memorial Award lecture. Cancer Res 49:1, 1989
    • (1989) Cancer Res , vol.49 , pp. 1
    • Brock, N.1
  • 38
    • 0029859821 scopus 로고    scopus 로고
    • Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes
    • Sandoval A, Consoli U, Plunkett W: Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes. Clin Cancer Res 2:1731, 1996
    • (1996) Clin Cancer Res , vol.2 , pp. 1731
    • Sandoval, A.1    Consoli, U.2    Plunkett, W.3
  • 43
    • 0032475878 scopus 로고    scopus 로고
    • Signaling to p53: Breaking the MDM2-p53 circuit
    • Prives C: Signaling to p53: Breaking the MDM2-p53 circuit. Cell 95:5, 1998
    • (1998) Cell , vol.95 , pp. 5
    • Prives, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.