Endowing indole-based tubulin inhibitors with an anchor for derivatization: Highly potent 3-substituted indolephenstatins and indoleisocombretastatins

Journal of Medicinal Chemistry

Volumn 56, Issue 7, 2013, Pages 2813-2827

  Álvarez, Raquel ^a   Puebla, Pilar ^a   Díaz, J Fernando ^b   Bento, Ana C ^a   García Navas, Rósula ^a   De La Iglesia Vicente, Janis ^a   Mollinedo, Faustino ^a   Andreu, José Manuel ^b   Medarde, Manuel ^a   Peláez, Rafael ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; COLCHICINE; INDOLE; LIGAND; PROTEIN INHIBITOR; TROPOLONE; TUBULIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL KILLING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DERIVATIZATION; DRUG BINDING; ENZYME ACTIVATION; FLUORESCENCE; HUMAN; HUMAN CELL; MOLECULAR MODEL; POLYMERIZATION; STRUCTURE ANALYSIS;

CELL LINE, TUMOR; HUMANS; INDOLES; TUBULIN MODULATORS;

EID: 84876236530     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3015603     Document Type: Article

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