Antineoplastic agents. 410. Asymmetric hydroxylation of trans- combretastatin A-4

Journal of Medicinal Chemistry

Volumn 42, Issue 8, 1999, Pages 1459-1465

  Pettit, George R ^a   Toki, Brian E ^a   Herald, Delbert L ^a   Boyd, Michael R ^b   Hamel, Ernest ^b   Pettit, Robin K ^a   Chapuis, J Charles ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(1,2) 1 (3 HYDROXY 4 METHOXYPHENYL) 2 (3',4',5' TRIMETHOXYPHENYL) 1,2 ETHANEDIOL; ANTINEOPLASTIC AGENT; COMBRETASTATIN A4; TUBULIN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CANCER; DRUG HYDROXYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ESTERIFICATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; TREE; TUMOR BLOOD FLOW;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; BACTERIA; BIOPOLYMERS; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; FUNGI; HUMANS; HYDROXYLATION; MICE; MODELS, MOLECULAR; STEREOISOMERISM; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0033594356     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9807149     Document Type: Article

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