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Volumn 98, Issue 4, 2013, Pages 1333-1342

Kinase inhibitors: Adverse effects related to the endocrine system

Author keywords

[No Author keywords available]

Indexed keywords

AXITINIB; BEVACIZUMAB; BISPHOSPHONIC ACID DERIVATIVE; BOSUTINIB; CABOZANTINIB; CETUXIMAB; CRIZOTINIB; DASATINIB; ERLOTINIB; GEFITINIB; IMATINIB; LAPATINIB; LEVOTHYROXINE; MONOCLONAL ANTIBODY; NILOTINIB; PAMIDRONIC ACID; PANITUMUMAB; PAZOPANIB; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PLACEBO; RUXOLITINIB; SMALL MOLECULE PHOSPHOTRANSFERASE INHIBITOR; SORAFENIB; SUNITINIB; TRASTUZUMAB; UNCLASSIFIED DRUG; VANDETANIB; VEMURAFENIB; ZOLEDRONIC ACID; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 84876223032     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-4085     Document Type: Review
Times cited : (87)

References (116)
  • 1
    • 22044442973 scopus 로고    scopus 로고
    • Tyrosine kinases as targets for cancer therapy
    • Krause DS, Van Etten RA. Tyrosine kinases as targets for cancer therapy. N Engl J Med. 2005;353:172-187.
    • (2005) N Engl J Med. , vol.353 , pp. 172-187
    • Krause, D.S.1    Van Etten, R.A.2
  • 2
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2000;103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 3
    • 84859410770 scopus 로고    scopus 로고
    • Phase II efficacy and pharmacogenomic study of selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements
    • Hayes DN, Lucas AS, Tanvetyanon T, et al. Phase II efficacy and pharmacogenomic study of selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements. Clin Cancer Res. 2012;18:2056-2065.
    • (2012) Clin Cancer Res. , vol.18 , pp. 2056-2065
    • Hayes, D.N.1    Lucas, A.S.2    Tanvetyanon, T.3
  • 4
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibitionin melanoma with BRAF V600 mutations
    • Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibitionin melanoma with BRAF V600 mutations. N Engl JMed. 2012;367:1694-1703.
    • (2012) N Engl JMed. , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1    Infante, J.R.2    Daud, A.3
  • 5
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364:2507-2516.
    • (2011) N Engl J Med. , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 6
    • 57749188299 scopus 로고    scopus 로고
    • Targeting cancer with small molecule kinase inhibitors
    • Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer. 2009;9:28-39.
    • (2009) Nat Rev Cancer , vol.9 , pp. 28-39
    • Zhang, J.1    Yang, P.L.2    Gray, N.S.3
  • 7
    • 77949871527 scopus 로고    scopus 로고
    • Kinase inhibitors: Narrowing down the real targets
    • Daub H. Kinase inhibitors: narrowing down the real targets. Nat Chem Biol. 2010;6:249-250.
    • (2010) Nat Chem Biol. , vol.6 , pp. 249-250
    • Daub, H.1
  • 8
    • 38049018155 scopus 로고    scopus 로고
    • A quantitative analysis of kinase inhibitor selectivity
    • Karaman MW, Herrgard S, Treiber DK, et al. A quantitative analysis of kinase inhibitor selectivity. Nat Biotechnol. 2008;26:127-132.
    • (2008) Nat Biotechnol. , vol.26 , pp. 127-132
    • Karaman, M.W.1    Herrgard, S.2    Treiber, D.K.3
  • 9
    • 19744365702 scopus 로고    scopus 로고
    • A small molecule-kinase interaction map for clinical kinaseinhibitors
    • Fabian MA, Biggs WH III, Treiber DK, et al. A small molecule-kinase interaction map for clinical kinaseinhibitors. Nat Biotechnol. 2005;23:329-336.
    • (2005) Nat Biotechnol. , vol.23 , pp. 329-336
    • Fabian, M.A.1    Biggs III, W.H.2    Treiber, D.K.3
  • 10
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med. , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 11
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med. 2004;351:337-345.
    • (2004) N Engl J Med. , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 12
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory meta-static colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory meta-static colorectal cancer. J Clin Oncol. 2007;25:1658-1664.
    • (2007) J Clin Oncol. , vol.25 , pp. 1658-1664
    • Van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 13
    • 0035869407 scopus 로고    scopus 로고
    • Use ofchemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al. Use ofchemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001;344:783-792.
    • (2001) N Engl J Med. , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 14
    • 38049025794 scopus 로고    scopus 로고
    • Review: Side effects of approved molecular targeted therapies in solid cancers
    • Widakowich C, de Castro G Jr, de Azambuja E, Dinh P, Awada A. Review: side effects of approved molecular targeted therapies in solid cancers. Oncologist. 2007;12:1443-1455.
    • (2007) Oncologist. , vol.12 , pp. 1443-1455
    • Widakowich, C.1    De Castro Jr., G.2    De Azambuja, E.3    Dinh, P.4    Awada, A.5
  • 15
    • 77956382293 scopus 로고    scopus 로고
    • Endocrine side effects of broad-acting kinase inhibitors
    • Lodish MB, Stratakis CA. Endocrine side effects of broad-acting kinase inhibitors. Endocr Relat Cancer. 2010;17:R233-R244.
    • (2010) Endocr Relat Cancer , vol.17
    • Lodish, M.B.1    Stratakis, C.A.2
  • 16
    • 67650173972 scopus 로고    scopus 로고
    • Hypothyroidism related to tyrosine kinase inhibitors: An emerging toxic effect of targeted therapy
    • Torino F, Corsello SM, Longo R, Barnabei A, Gasparini G. Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. Nat Rev Clin Oncol. 2009;6:219-228.
    • (2009) Nat Rev Clin Oncol. , vol.6 , pp. 219-228
    • Torino, F.1    Corsello, S.M.2    Longo, R.3    Barnabei, A.4    Gasparini, G.5
  • 17
    • 58149463969 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors and the thyroid as both an unintended and an intended target
    • Vetter ML, Kaul S, Iqbal N. Tyrosine kinase inhibitors and the thyroid as both an unintended and an intended target. Endocr Pract. 2008;14:618-624.
    • (2008) Endocr Pract. , vol.14 , pp. 618-624
    • Vetter, M.L.1    Kaul, S.2    Iqbal, N.3
  • 18
    • 84856071108 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor-induced hypothyroidism: Incidence, etiology, and management
    • Brown RL. Tyrosine kinase inhibitor-induced hypothyroidism: incidence, etiology, and management. Target Oncol. 2011;6:217-226.
    • (2011) Target Oncol. , vol.6 , pp. 217-226
    • Brown, R.L.1
  • 22
    • 77955374095 scopus 로고    scopus 로고
    • Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination
    • Abdulrahman RM, Verloop H, Hoftijzer H, et al. Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. J Clin Endocrinol Metab. 2010;95:3758-3762.
    • (2010) J Clin Endocrinol Metab. , vol.95 , pp. 3758-3762
    • Abdulrahman, R.M.1    Verloop, H.2    Hoftijzer, H.3
  • 23
    • 50649095250 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in advanced thyroid cancer
    • Gupta-Abramson V, Troxel AB, Nellore A, et al. Phase II trial of sorafenib in advanced thyroid cancer. J Clin Oncol. 2008;26:4714-4719.
    • (2008) J Clin Oncol. , vol.26 , pp. 4714-4719
    • Gupta-Abramson, V.1    Troxel, A.B.2    Nellore, A.3
  • 24
    • 43149125384 scopus 로고    scopus 로고
    • Lack of imatinib-induced thyroid dysfunction in a cohort of non-thyroidectomized patients
    • Dora JM, Leie MA, Netto B, et al. Lack of imatinib-induced thyroid dysfunction in a cohort of non-thyroidectomized patients. Eur J Endocrinol. 2008;158:771-772.
    • (2008) Eur J Endocrinol. , vol.158 , pp. 771-772
    • Dora, J.M.1    Leie, M.A.2    Netto, B.3
  • 25
    • 84655175698 scopus 로고    scopus 로고
    • Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind phase III trial
    • Wells SA Jr, Robinson BG, Gagel RF, et al. Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial. J Clin Oncol. 2012;30: 134-141.
    • (2012) J Clin Oncol. , vol.30 , pp. 134-141
    • Wells Jr., S.A.1    Robinson, B.G.2    Gagel, R.F.3
  • 26
    • 33750961647 scopus 로고    scopus 로고
    • Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors
    • Desai J, Yassa L, Marqusee E, et al. Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Ann Intern Med. 2006;145:660-664.
    • (2006) Ann Intern Med. , vol.145 , pp. 660-664
    • Desai, J.1    Yassa, L.2    Marqusee, E.3
  • 27
    • 48349122489 scopus 로고    scopus 로고
    • The clinical implications of sunitinib-induced hypothyroidism: A prospective evaluation
    • Wolter P, Stefan C, Decallonne B, et al. The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. Br J Cancer. 2008;99:448-454.
    • (2008) Br J Cancer , vol.99 , pp. 448-454
    • Wolter, P.1    Stefan, C.2    Decallonne, B.3
  • 28
    • 34248632840 scopus 로고    scopus 로고
    • Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
    • Wong E, Rosen LS, Mulay M, et al. Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid. 2007;17:351-355.
    • (2007) Thyroid , vol.17 , pp. 351-355
    • Wong, E.1    Rosen, L.S.2    Mulay, M.3
  • 29
    • 33846978108 scopus 로고    scopus 로고
    • Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib
    • Rini BI, Tamaskar I, Shaheen P, et al. Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst. 2007;99:81-83.
    • (2007) J Natl Cancer Inst. , vol.99 , pp. 81-83
    • Rini, B.I.1    Tamaskar, I.2    Shaheen, P.3
  • 30
    • 38849093794 scopus 로고    scopus 로고
    • Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib
    • Tamaskar I, Bukowski R, Elson P, et al. Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. Ann Oncol. 2008;19:265-268.
    • (2008) Ann Oncol. , vol.19 , pp. 265-268
    • Tamaskar, I.1    Bukowski, R.2    Elson, P.3
  • 31
    • 78249244171 scopus 로고    scopus 로고
    • Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia
    • Kim TD, Schwarz M, Nogai H, et al. Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia. Thyroid. 2010;20: 1209-1214.
    • (2010) Thyroid , vol.20 , pp. 1209-1214
    • Kim, T.D.1    Schwarz, M.2    Nogai, H.3
  • 32
    • 82755183572 scopus 로고    scopus 로고
    • Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): A randomised phase 3 trial
    • Rini BI, Escudier B, Tomczak P, et al. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial. Lancet. 2011;378:1931-1939.
    • (2011) Lancet. , vol.378 , pp. 1931-1939
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 33
    • 33845313204 scopus 로고    scopus 로고
    • Sunitinib-related thyroid dysfunction: A single-center retrospective and prospective evaluation
    • June 2-6 Atlanta, GA. Abstract 3092
    • Schoeffski P, Wolter P, Himpe U, et al. Sunitinib-related thyroid dysfunction: a single-center retrospective and prospective evaluation. In: Proceedings from the American Society of Clinical Oncology; June 2-6, 2006; Atlanta, GA. Abstract 3092.
    • (2006) Proceedings from the American Society of Clinical Oncology
    • Schoeffski, P.1    Wolter, P.2    Himpe, U.3
  • 34
    • 77956386386 scopus 로고    scopus 로고
    • Receptor kinase (RTK) inhibitor SU11248 may cause hypothyroidism in a select group of patients with metastatic renal cell carcinoma (RCC)
    • June 24-27 Boston, MA. Abstract 593
    • Martorella AJ, Omry G, Hann LE, Motzer RJ, Robbins RJ. Receptor kinase (RTK) inhibitor SU11248 may cause hypothyroidism in a select group of patients with metastatic renal cell carcinoma (RCC). In: Proceedings from the 88th Annual Meeting of The Endocrine Society; June 24-27, 2006; Boston, MA. Abstract 593.
    • (2006) Proceedings from the 88th Annual Meeting of the Endocrine Society
    • Martorella, A.J.1    Omry, G.2    Hann, L.E.3    Motzer, R.J.4    Robbins, R.J.5
  • 35
    • 34248673607 scopus 로고    scopus 로고
    • 2006 Thyroid function tests (TFTs) abnormalities in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib
    • June 2-6 Atlanta, GA. Abstract 4605
    • Shaheen PE, Tamaskar IR, Salas RN, et al. 2006 Thyroid function tests (TFTs) abnormalities in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib. In: Proceedings from the American Society of Clinical Oncology; June 2-6, 2006; Atlanta, GA. Abstract 4605.
    • (2006) Proceedings from the American Society of Clinical Oncology
    • Shaheen, P.E.1    Tamaskar, I.R.2    Salas, R.N.3
  • 36
    • 34548764576 scopus 로고    scopus 로고
    • A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
    • Mannavola D, Coco P, Vannucchi G, et al. A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. J Clin Endocrinol Metab. 2007;92:3531-3534.
    • (2007) J Clin Endocrinol Metab. , vol.92 , pp. 3531-3534
    • Mannavola, D.1    Coco, P.2    Vannucchi, G.3
  • 39
    • 77649291310 scopus 로고    scopus 로고
    • Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: A potential marker of irreversible thyroid dysfunction?
    • Rogiers A, Wolter P, Op de Beeck K, Thijs M, Decallonne B, Schoffski P. Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction? Thyroid. 2010;20:317-322.
    • (2010) Thyroid , vol.20 , pp. 317-322
    • Rogiers, A.1    Wolter, P.2    Op De Beeck, K.3    Thijs, M.4    Decallonne, B.5    Schoffski, P.6
  • 40
    • 77649310826 scopus 로고    scopus 로고
    • Sunitinib induces hypothyroidism with a markedly reduced vascularity
    • Makita N, Miyakawa M, Fujita T, Iiri T. Sunitinib induces hypothyroidism with a markedly reduced vascularity. Thyroid. 2010;20: 323-326.
    • (2010) Thyroid , vol.20 , pp. 323-326
    • Makita, N.1    Miyakawa, M.2    Fujita, T.3    Iiri, T.4
  • 42
    • 34247501288 scopus 로고    scopus 로고
    • Imatinib mesylate induces hypophosphatemia in patients with chronic myeloid leukemia in late chronic phase, and this effect is associated with response
    • Osorio S, Noblejas AG, Duran A, Steegmann JL. Imatinib mesylate induces hypophosphatemia in patients with chronic myeloid leukemia in late chronic phase, and this effect is associated with response. Am J Hematol. 2007;82:394-395.
    • (2007) Am J Hematol. , vol.82 , pp. 394-395
    • Osorio, S.1    Noblejas, A.G.2    Duran, A.3    Steegmann, J.L.4
  • 43
    • 33845452829 scopus 로고    scopus 로고
    • Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism
    • Grey A, O'Sullivan S, Reid IR, Browett P. Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism. N Engl J Med. 2006;355:2494-2495.
    • (2006) N Engl J Med. , vol.355 , pp. 2494-2495
    • Grey, A.1    O'Sullivan, S.2    Reid, I.R.3    Browett, P.4
  • 44
    • 33646482407 scopus 로고    scopus 로고
    • Altered bone and mineral metabolism in patients receiving imatinib mesylate
    • Berman E, Nicolaides M, Maki RG, et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med. 2006;354:2006-2013.
    • (2006) N Engl J Med. , vol.354 , pp. 2006-2013
    • Berman, E.1    Nicolaides, M.2    Maki, R.G.3
  • 45
    • 41949120243 scopus 로고    scopus 로고
    • Long-term imatinib therapy promotes bone formation in CML patients
    • Fitter S, Dewar AL, Kostakis P, et al. Long-term imatinib therapy promotes bone formation in CML patients. Blood.2008;111:2538-2547.
    • (2008) Blood , vol.111 , pp. 2538-2547
    • Fitter, S.1    Dewar, A.L.2    Kostakis, P.3
  • 46
    • 84861841611 scopus 로고    scopus 로고
    • Sunitinib-induced hyperparathyroidism: A possible mechanism toaltered bone homeostasis
    • Baldazzi V, Tassi R, Lapini A, et al. Sunitinib-induced hyperparathyroidism: a possible mechanism toaltered bone homeostasis. Cancer. 2012;118:3165-3172.
    • (2012) Cancer , vol.118 , pp. 3165-3172
    • Baldazzi, V.1    Tassi, R.2    Lapini, A.3
  • 47
    • 80052549851 scopus 로고    scopus 로고
    • Endocrine effects of the tyrosine kinase inhibitor vandetanib in patients treated for thyroid cancer
    • Brassard M, Neraud B, Trabado S, et al. Endocrine effects of the tyrosine kinase inhibitor vandetanib in patients treated for thyroid cancer. J Clin Endocrinol Metab. 2011;96:2741-2749.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 2741-2749
    • Brassard, M.1    Neraud, B.2    Trabado, S.3
  • 48
    • 79958770455 scopus 로고    scopus 로고
    • The skeletal effects of the tyrosine kinase inhibitor nilotinib
    • O'Sullivan S, Lin JM, Watson M, et al. The skeletal effects of the tyrosine kinase inhibitor nilotinib. Bone. 2011;49:281-289.
    • (2011) Bone , vol.49 , pp. 281-289
    • O'Sullivan, S.1    Lin, J.M.2    Watson, M.3
  • 49
    • 33746895510 scopus 로고    scopus 로고
    • Imatinib and altered bone and mineral metabolism
    • author reply 628-629
    • Joensuu H, Reichardt P. Imatinib and altered bone and mineral metabolism. N Engl J Med. 2006;355:628; author reply 628-629.
    • (2006) N Engl J Med. , vol.355 , pp. 628
    • Joensuu, H.1    Reichardt, P.2
  • 50
    • 33746903194 scopus 로고    scopus 로고
    • Imatinib and altered bone and mineral metabolism
    • author reply 628-629
    • Owen S, Hatfield A, Letvak L. Imatinib and altered bone and mineral metabolism. N Engl J Med. 2006;355:627; author reply 628-629.
    • (2006) N Engl J Med. , vol.355 , pp. 627
    • Owen, S.1    Hatfield, A.2    Letvak, L.3
  • 51
    • 33746903194 scopus 로고    scopus 로고
    • Imatinib and altered bone and mineral metabolism
    • author reply 628-629
    • Tournis S, Lyritis GP. Imatinib and altered bone and mineral metabolism. N Engl J Med. 2006;355:627; author reply 628-629.
    • (2006) N Engl J Med. , vol.355 , pp. 627
    • Tournis, S.1    Lyritis, G.P.2
  • 52
    • 46849094125 scopus 로고    scopus 로고
    • Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia
    • Jonsson S, Olsson B, Ohlsson C, Lorentzon M, Mellstrom D, Wadenvik H. Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia. Haematologica. 2008;93:1101-1103.
    • (2008) Haematologica. , vol.93 , pp. 1101-1103
    • Jonsson, S.1    Olsson, B.2    Ohlsson, C.3    Lorentzon, M.4    Mellstrom, D.5    Wadenvik, H.6
  • 53
    • 65249162967 scopus 로고    scopus 로고
    • Decreased bone turnover despite persistent secondary hyperparathyroidism during prolonged treatment with imatinib
    • O'Sullivan S, Horne A, Wattie D, et al. Decreased bone turnover despite persistent secondary hyperparathyroidism during prolonged treatment with imatinib. J Clin Endocrinol Metab. 2009;94:1131-1136.
    • (2009) J Clin Endocrinol Metab. , vol.94 , pp. 1131-1136
    • O'Sullivan, S.1    Horne, A.2    Wattie, D.3
  • 54
    • 84859909310 scopus 로고    scopus 로고
    • Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib
    • Jonsson S, Standal T, Olsson B, Mellstrom D, Wadenvik H. Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib. Am J Hematol. 2012;87:550-552.
    • (2012) Am J Hematol. , vol.87 , pp. 550-552
    • Jonsson, S.1    Standal, T.2    Olsson, B.3    Mellstrom, D.4    Wadenvik, H.5
  • 55
    • 77955750697 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor dasatinib dysregulates bone remodeling through inhibition of osteoclasts in vivo
    • Vandyke K, Dewar AL, Diamond P, et al. The tyrosine kinase inhibitor dasatinib dysregulates bone remodeling through inhibition of osteoclasts in vivo. J Bone Miner Res. 2010;25:1759-1770.
    • (2010) J Bone Miner Res. , vol.25 , pp. 1759-1770
    • Vandyke, K.1    Dewar, A.L.2    Diamond, P.3
  • 56
    • 77953559069 scopus 로고    scopus 로고
    • The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts
    • Id Boufker H, Lagneaux L, Najar M, et al. The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts. BMC Cancer. 2010;10:298.
    • (2010) BMC Cancer , vol.10 , pp. 298
    • Id Boufker, H.1    Lagneaux, L.2    Najar, M.3
  • 57
    • 84857546448 scopus 로고    scopus 로고
    • Phase II study of singleagent bosutinib, a Src/Abl tyrosine kinase inhibitor, in patients with locally advanced or metastatic breast cancer pretreated with chemotherapy
    • Campone M, Bondarenko I, Brincat S, et al. Phase II study of singleagent bosutinib, a Src/Abl tyrosine kinase inhibitor, in patients with locally advanced or metastatic breast cancer pretreated with chemotherapy. Ann Oncol. 2012;23:610-617.
    • (2012) Ann Oncol. , vol.23 , pp. 610-617
    • Campone, M.1    Bondarenko, I.2    Brincat, S.3
  • 58
    • 83855162892 scopus 로고    scopus 로고
    • Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a phase 1-2 study
    • Araujo JC, Mathew P, Armstrong AJ, et al. Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study. Cancer. 2012;118:63-71.
    • (2012) Cancer , vol.118 , pp. 63-71
    • Araujo, J.C.1    Mathew, P.2    Armstrong, A.J.3
  • 59
    • 77957111700 scopus 로고    scopus 로고
    • Sunitinib may raise the risk of bisphosphonate-related osteonecrosis of the jaw: Presentation of three cases
    • Hoefert S, Eufinger H. Sunitinib may raise the risk of bisphosphonate-related osteonecrosis of the jaw: presentation of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110: 463-469.
    • (2010) Oral Surg Oral Med Oral Pathol Oral Radiol Endod. , vol.110 , pp. 463-469
    • Hoefert, S.1    Eufinger, H.2
  • 63
    • 59749100961 scopus 로고    scopus 로고
    • Combination of bisphosphonates and antiangiogenic factors induces osteonecrosis of the jaw more frequently than bisphosphonates alone
    • Christodoulou C, Pervena A, Klouvas G, et al. Combination of bisphosphonates and antiangiogenic factors induces osteonecrosis of the jaw more frequently than bisphosphonates alone. Oncology. 2009;76:209-211.
    • (2009) Oncology , vol.76 , pp. 209-211
    • Christodoulou, C.1    Pervena, A.2    Klouvas, G.3
  • 64
    • 80052746518 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw: Dental outcomes in meta-static breast cancer patients treated with bisphosphonates with/without bevacizumab
    • Ngamphaiboon N, Frustino JL, Kossoff EB, Sullivan MA, O'Connor TL. Osteonecrosis of the jaw: dental outcomes in meta-static breast cancer patients treated with bisphosphonates with/without bevacizumab. Clin Breast Cancer. 2011;11:252-257.
    • (2011) Clin Breast Cancer , vol.11 , pp. 252-257
    • Ngamphaiboon, N.1    Frustino, J.L.2    Kossoff, E.B.3    Sullivan, M.A.4    O'Connor, T.L.5
  • 65
    • 84876258428 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw (ONJ) among intravenous (IV) bisphosphonate- and/or bevacizumab-treated patients (pts) at Memorial Sloan-Kettering Cancer Center (MSKCC)
    • May 30-June 3 Chicago, IL. Abstract 9588
    • McArthur HL, Estilo C, Huryn J, et al. Osteonecrosis of the jaw (ONJ) among intravenous (IV) bisphosphonate- and/or bevacizumab-treated patients (pts) at Memorial Sloan-Kettering Cancer Center (MSKCC). In: Proceedings from the American Society of Clinical Oncology; May 30-June 3, 2008; Chicago, IL. Abstract 9588.
    • (2008) Proceedings from the American Society of Clinical Oncology
    • McArthur, H.L.1    Estilo, C.2    Huryn, J.3
  • 66
    • 77953534421 scopus 로고    scopus 로고
    • Bevacizumab and osteonecrosis of the jaw: Incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer
    • Guarneri V, Miles D, Robert N, et al. Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer. Breast Cancer Res Treat. 2010;122:181-188.
    • (2010) Breast Cancer Res Treat. , vol.122 , pp. 181-188
    • Guarneri, V.1    Miles, D.2    Robert, N.3
  • 67
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber HP, Vu TH, Ryan AM, Kowalski J, Werb Z, Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med. 1999; 5:623-628.
    • (1999) Nat Med. , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3    Kowalski, J.4    Werb, Z.5    Ferrara, N.6
  • 68
    • 70450277310 scopus 로고    scopus 로고
    • Imatinib mesylate causes growth plate closure in vivo
    • Vandyke K, Dewar AL, Fitter S, et al. Imatinib mesylate causes growth plate closure in vivo. Leukemia. 2009;23:2155-2159.
    • (2009) Leukemia , vol.23 , pp. 2155-2159
    • Vandyke, K.1    Dewar, A.L.2    Fitter, S.3
  • 70
    • 67349264054 scopus 로고    scopus 로고
    • Growth deceleration in a girl treated with imatinib
    • Kimoto T, Inoue M, Kawa K. Growth deceleration in a girl treated with imatinib. Int J Hematol. 2009;89:251-252.
    • (2009) Int J Hematol. , vol.89 , pp. 251-252
    • Kimoto, T.1    Inoue, M.2    Kawa, K.3
  • 71
    • 46949090042 scopus 로고    scopus 로고
    • Low bone density and decreased inhibin-B/FSH ratio in a boy treated with imatinib during puberty
    • Mariani S, Giona F, Basciani S, Brama M, Gnessi L. Low bone density and decreased inhibin-B/FSH ratio in a boy treated with imatinib during puberty. Lancet. 2008;372:111-112.
    • (2008) Lancet. , vol.372 , pp. 111-112
    • Mariani, S.1    Giona, F.2    Basciani, S.3    Brama, M.4    Gnessi, L.5
  • 72
    • 68049137764 scopus 로고    scopus 로고
    • Longitudinal growth retardation in a prepubertal girl with chronic myeloid leukemia on long-term treatment with imatinib
    • Schmid H, Jaeger BA, Lohse J, Suttorp M. Longitudinal growth retardation in a prepubertal girl with chronic myeloid leukemia on long-term treatment with imatinib. Haematologica. 2009;94:1177-1179.
    • (2009) Haematologica. , vol.94 , pp. 1177-1179
    • Schmid, H.1    Jaeger, B.A.2    Lohse, J.3    Suttorp, M.4
  • 73
    • 79551622697 scopus 로고    scopus 로고
    • Acquired growth hormone deficiency in a girl with chronic myelogenous leukemia treated with tyrosine kinase inhibitor therapy
    • Hobernicht SL, Schweiger B, Zeitler P, Wang M, Hunger SP. Acquired growth hormone deficiency in a girl with chronic myelogenous leukemia treated with tyrosine kinase inhibitor therapy. Pediatr Blood Cancer. 2011;56:671-673.
    • (2011) Pediatr Blood Cancer , vol.56 , pp. 671-673
    • Hobernicht, S.L.1    Schweiger, B.2    Zeitler, P.3    Wang, M.4    Hunger, S.P.5
  • 74
    • 84863865642 scopus 로고    scopus 로고
    • Imatinib has adverse effect on growth in children with chronic myeloid leukemia
    • Bansal D, Shava U, Varma N, Trehan A, Marwaha RK. Imatinib has adverse effect on growth in children with chronic myeloid leukemia. Pediatr Blood Cancer. 2012;59:481-484.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 481-484
    • Bansal, D.1    Shava, U.2    Varma, N.3    Trehan, A.4    Marwaha, R.K.5
  • 75
    • 80052790433 scopus 로고    scopus 로고
    • Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia
    • Shima H, Tokuyama M, Tanizawa A, et al. Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia. J Pediatr. 2011;159:676-681.
    • (2011) J Pediatr. , vol.159 , pp. 676-681
    • Shima, H.1    Tokuyama, M.2    Tanizawa, A.3
  • 76
    • 84876221518 scopus 로고    scopus 로고
    • Imatinib is efficient but has a negative impact on growth in children with previously untreated chronic myelogenous leukaemia (CML) in early chronic phase (CP): Results of the French National Phase IV Trial
    • December 5-9 New Orleans, LA. Abstract 863
    • Millot F, Baruchel A, Guilhot J, et al. Imatinib is efficient but has a negative impact on growth in children with previously untreated chronic myelogenous leukaemia (CML) in early chronic phase (CP): results of the French National Phase IV Trial. In: Proceedings from the American Society of Hematology Annual Meeting; December 5-9, 2009; New Orleans, LA. Abstract 863.
    • (2009) Proceedings from the American Society of Hematology Annual Meeting
    • Millot, F.1    Baruchel, A.2    Guilhot, J.3
  • 77
    • 33645014406 scopus 로고    scopus 로고
    • Review of the effects of anti-angiogenic compoundsonthe epiphyseal growth plate
    • Hall AP, Westwood FR, Wadsworth PF. Review of the effects of anti-angiogenic compoundsonthe epiphyseal growth plate. Toxicol Pathol. 2006;34:131-147.
    • (2006) Toxicol Pathol. , vol.34 , pp. 131-147
    • Hall, A.P.1    Westwood, F.R.2    Wadsworth, P.F.3
  • 78
    • 68249146142 scopus 로고    scopus 로고
    • Does imatinib mesylate therapy cause growth hormone deficiency?
    • Kebapcilar L, Bilgir O, Alacacioglu I, et al. Does imatinib mesylate therapy cause growth hormone deficiency? Med Princ Pract. 2009; 18:360-363.
    • (2009) Med Princ Pract. , vol.18 , pp. 360-363
    • Kebapcilar, L.1    Bilgir, O.2    Alacacioglu, I.3
  • 80
    • 84871734237 scopus 로고    scopus 로고
    • Imatinib-associated bilateral gynecomastia and unilateral testicular hydrocele in male patient with metastatic gastrointestinal stromal tumor: A literature review
    • Tanriverdi O, Unubol M, Taskin F, et al. Imatinib-associated bilateral gynecomastia and unilateral testicular hydrocele in male patient with metastatic gastrointestinal stromal tumor: a literature review. J Oncol Pharm Pract. 2012;18:303-310.
    • (2012) J Oncol Pharm Pract. , vol.18 , pp. 303-310
    • Tanriverdi, O.1    Unubol, M.2    Taskin, F.3
  • 81
    • 56249093801 scopus 로고    scopus 로고
    • Gynecomastia in a male after dasatinib treatment for chronic myeloid leukemia
    • Caocci G, Atzeni S, Orru N, et al. Gynecomastia in a male after dasatinib treatment for chronic myeloid leukemia. Leukemia. 2008; 22:2127-2128.
    • (2008) Leukemia , vol.22 , pp. 2127-2128
    • Caocci, G.1    Atzeni, S.2    Orru, N.3
  • 82
    • 67650312348 scopus 로고    scopus 로고
    • Onset of male gynaecomastia in a patient treated with sunitinib for metastatic renal cell carcinoma
    • Ballardini P, Margutti G, Aliberti C, Manfredini R. Onset of male gynaecomastia in a patient treated with sunitinib for metastatic renal cell carcinoma. Clin Drug Investig. 2009;29:487-490.
    • (2009) Clin Drug Investig , vol.29 , pp. 487-490
    • Ballardini, P.1    Margutti, G.2    Aliberti, C.3    Manfredini, R.4
  • 83
    • 21344448848 scopus 로고    scopus 로고
    • Concurrent male gynecomastia and testicular hydrocele after imatinib mesylate treatment of a gastrointestinal stromal tumor
    • Kim H, Chang HM, Ryu MH, et al. Concurrent male gynecomastia and testicular hydrocele after imatinib mesylate treatment of a gastrointestinal stromal tumor. J Korean Med Sci. 2005;20:512-515.
    • (2005) J Korean Med Sci. , vol.20 , pp. 512-515
    • Kim, H.1    Chang, H.M.2    Ryu, M.H.3
  • 84
    • 10744230733 scopus 로고    scopus 로고
    • Gynaecomastia in men with chronic myeloid leukaemia after imatinib
    • Gambacorti-Passerini C, Tornaghi L, Cavagnini F, et al. Gynaecomastia in men with chronic myeloid leukaemia after imatinib. Lancet. 2003;361:1954-1956.
    • (2003) Lancet. , vol.361 , pp. 1954-1956
    • Gambacorti-Passerini, C.1    Tornaghi, L.2    Cavagnini, F.3
  • 85
    • 18344362452 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor - A (PDGF-A), PDGF-B, and PDGF receptor-α and -β during human testicular development and disease
    • Basciani S, Mariani S, Arizzi M, et al. Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-α and -β during human testicular development and disease. J Clin Endocrinol Metab. 2002;87:2310-2319.
    • (2002) J Clin Endocrinol Metab. , vol.87 , pp. 2310-2319
    • Basciani, S.1    Mariani, S.2    Arizzi, M.3
  • 86
    • 0142243109 scopus 로고    scopus 로고
    • Roles of PDGF in animal development
    • Hoch RV, Soriano P. Roles of PDGF in animal development. Development. 2003;130:4769-4784.
    • (2003) Development , vol.130 , pp. 4769-4784
    • Hoch, R.V.1    Soriano, P.2
  • 87
    • 84876207201 scopus 로고    scopus 로고
    • Genetech Corporation Updated October 2012. Accessed December 3, 2012
    • Genetech Corporation. Avastatin (bevacizumab): highlights of prescribing information. http://www.gene.com/gene/products/information/pdf/avastin- prescribing.pdf Updated October 2012. Accessed December 3, 2012.
    • Avastatin (bevacizumab): Highlights of Prescribing Information
  • 88
    • 79951952200 scopus 로고    scopus 로고
    • Severe oligozoospermia in a young man with chronic myeloid leukemia on long-term treatment with imatinib started before puberty
    • Mariani S, Basciani S, Fabbri A, et al. Severe oligozoospermia in a young man with chronic myeloid leukemia on long-term treatment with imatinib started before puberty. Fertil Steril. 2011;95: 1120.e15-e17.
    • (2011) Fertil Steril. , vol.95
    • Mariani, S.1    Basciani, S.2    Fabbri, A.3
  • 89
    • 40449095966 scopus 로고    scopus 로고
    • Primary ovarian insufficiency associated with imatinib therapy
    • Christopoulos C, Dimakopoulou V, Rotas E. Primary ovarian insufficiency associated with imatinib therapy. N Engl J Med. 2008; 358:1079-1080.
    • (2008) N Engl J Med. , vol.358 , pp. 1079-1080
    • Christopoulos, C.1    Dimakopoulou, V.2    Rotas, E.3
  • 90
    • 80054795412 scopus 로고    scopus 로고
    • Will imatinib compromise reproductive capacity?
    • Zamah AM, Mauro MJ, Druker BJ, et al. Will imatinib compromise reproductive capacity? Oncologist. 2011;16:1422-1427.
    • (2011) Oncologist. , vol.16 , pp. 1422-1427
    • Zamah, A.M.1    Mauro, M.J.2    Druker, B.J.3
  • 91
    • 84855941960 scopus 로고    scopus 로고
    • Imatinib mesylate at therapeutic doses has no impact on folliculogenesis or spermatogenesis in a leukaemic mouse model
    • Schultheis B, Nijmeijer BA, Yin H, Gosden RG, Melo JV. Imatinib mesylate at therapeutic doses has no impact on folliculogenesis or spermatogenesis in a leukaemic mouse model. Leuk Res. 2012;36: 271-274.
    • (2012) Leuk Res. , vol.36 , pp. 271-274
    • Schultheis, B.1    Nijmeijer, B.A.2    Yin, H.3    Gosden, R.G.4    Melo, J.V.5
  • 92
    • 0037497262 scopus 로고    scopus 로고
    • Imatinib treatment: Specific issues related to safety, fertility, and pregnancy
    • Hensley ML, Ford JM. Imatinib treatment: specific issues related to safety, fertility, and pregnancy. Semin Hematol. 2003;40(2 suppl 2):21-25.
    • (2003) Semin Hematol. , vol.40 , Issue.2 SUPPL. 2 , pp. 21-25
    • Hensley, M.L.1    Ford, J.M.2
  • 93
    • 33644984830 scopus 로고    scopus 로고
    • Pregnancy among patients with chronic myeloid leukemia treated with imatinib
    • Ault P, Kantarjian H, O'Brien S, et al. Pregnancy among patients with chronic myeloid leukemia treated with imatinib. J Clin Oncol. 2006;24:1204-1208.
    • (2006) J Clin Oncol. , vol.24 , pp. 1204-1208
    • Ault, P.1    Kantarjian, H.2    O'Brien, S.3
  • 94
    • 34247524263 scopus 로고    scopus 로고
    • Successful pregnancies involving men with chronic myeloid leukaemia on imatinib therapy
    • Ramasamy K, Hayden J, Lim Z, Mufti GJ, Ho AY. Successful pregnancies involving men with chronic myeloid leukaemia on imatinib therapy. Br J Haematol. 2007;137:374-375.
    • (2007) Br J Haematol. , vol.137 , pp. 374-375
    • Ramasamy, K.1    Hayden, J.2    Lim, Z.3    Mufti, G.J.4    Ho, A.Y.5
  • 95
    • 39749089552 scopus 로고    scopus 로고
    • Male patients with chronic myeloid leukemia treated with imatinib involved in healthy pregnancies: Report of five cases
    • Breccia M, Cannella L, Montefusco E, Frustaci A, Pacilli M, Alimena G. Male patients with chronic myeloid leukemia treated with imatinib involved in healthy pregnancies: report of five cases. Leuk Res. 2008;32:519-520.
    • (2008) Leuk Res. , vol.32 , pp. 519-520
    • Breccia, M.1    Cannella, L.2    Montefusco, E.3    Frustaci, A.4    Pacilli, M.5    Alimena, G.6
  • 96
    • 74049088287 scopus 로고    scopus 로고
    • Issues of imatinib and pregnancy outcome
    • Apperley J. Issues of imatinib and pregnancy outcome. J Natl Compr Canc Netw. 2009;7:1050-1058.
    • (2009) J Natl Compr Canc Netw. , vol.7 , pp. 1050-1058
    • Apperley, J.1
  • 97
    • 47049124097 scopus 로고    scopus 로고
    • The effects of imatinib on pregnancy outcome
    • Pye SM, Cortes J, Ault P, et al. The effects of imatinib on pregnancy outcome. Blood. 2008;111:5505-5508.
    • (2008) Blood , vol.111 , pp. 5505-5508
    • Pye, S.M.1    Cortes, J.2    Ault, P.3
  • 98
    • 0030808324 scopus 로고    scopus 로고
    • The PDGF α receptor is required for neural crest cell development and for normal patterning of the somites
    • Soriano P. The PDGF α receptor is required for neural crest cell development and for normal patterning of the somites. Development. 1997;124:2691-2700.
    • (1997) Development , vol.124 , pp. 2691-2700
    • Soriano, P.1
  • 99
    • 84860330520 scopus 로고    scopus 로고
    • Pregnancy occurring during or following adjuvant trastuzumab in patients enrolled in the HERA trial (BIG 01-01)
    • Azim HA Jr, Metzger-Filho O, de Azambuja E, et al. Pregnancy occurring during or following adjuvant trastuzumab in patients enrolled in the HERA trial (BIG 01-01). Breast Cancer Res Treat. 2012;133:387-391.
    • (2012) Breast Cancer Res Treat. , vol.133 , pp. 387-391
    • Azim Jr., H.A.1    Metzger-Filho, O.2    De Azambuja, E.3
  • 100
    • 78049420497 scopus 로고    scopus 로고
    • Treatment of cancer during pregnancy with monoclonal antibodies: A real challenge
    • Azim HA Jr, Azim H, Peccatori FA. Treatment of cancer during pregnancy with monoclonal antibodies: a real challenge. Expert Rev Clin Immunol. 2010;6:821-826.
    • (2010) Expert Rev Clin Immunol. , vol.6 , pp. 821-826
    • Azim Jr., H.A.1    Azim, H.2    Peccatori, F.A.3
  • 101
    • 33644552719 scopus 로고    scopus 로고
    • G-Protein-coupled receptors and tyrosine kinases: Crossroads in cell signaling and regulation
    • Gavi S, Shumay E, Wang HY, Malbon CC. G-Protein-coupled receptors and tyrosine kinases: crossroads in cell signaling and regulation. Trends Endocrinol Metab. 2006;17:48-54.
    • (2006) Trends Endocrinol Metab. , vol.17 , pp. 48-54
    • Gavi, S.1    Shumay, E.2    Wang, H.Y.3    Malbon, C.C.4
  • 102
    • 34547483563 scopus 로고    scopus 로고
    • Targeted treatment using monoclonal antibodies and tyrosine-kinase inhibitors in pregnancy
    • Robinson AA, Watson WJ, Leslie KK. Targeted treatment using monoclonal antibodies and tyrosine-kinase inhibitors in pregnancy. Lancet Oncol. 2007;8:738-743.
    • (2007) Lancet Oncol. , vol.8 , pp. 738-743
    • Robinson, A.A.1    Watson, W.J.2    Leslie, K.K.3
  • 103
    • 84855748821 scopus 로고    scopus 로고
    • Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer
    • Gucalp A, Sparano JA, Caravelli J, et al. Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. Clin Breast Cancer. 2011;11:306-311.
    • (2011) Clin Breast Cancer , vol.11 , pp. 306-311
    • Gucalp, A.1    Sparano, J.A.2    Caravelli, J.3
  • 104
    • 72449203226 scopus 로고    scopus 로고
    • Is there any relationship between imatinib mesylate medication and hypothalamic-pituitary-adrenal axis dysfunction?
    • Bilgir O, Kebapcilar L, Bilgir F, et al. Is there any relationship between imatinib mesylate medication and hypothalamic-pituitary-adrenal axis dysfunction? Int J Clin Pract. 2010;64:45-50.
    • (2010) Int J Clin Pract. , vol.64 , pp. 45-50
    • Bilgir, O.1    Kebapcilar, L.2    Bilgir, F.3
  • 105
    • 33846440150 scopus 로고    scopus 로고
    • Food and Drug Administration drug approval summary: Sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma
    • Rock EP, Goodman V, Jiang JX, et al. Food and Drug Administration drug approval summary: sunitinib malate for the treatment of gastrointestinal stromal tumor and advanced renal cell carcinoma. Oncologist. 2007;12:107-113.
    • (2007) Oncologist. , vol.12 , pp. 107-113
    • Rock, E.P.1    Goodman, V.2    Jiang, J.X.3
  • 106
    • 55249116969 scopus 로고    scopus 로고
    • Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
    • Billemont B, Medioni J, Taillade L, et al. Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib. Br J Cancer. 2008;99:1380-1382.
    • (2008) Br J Cancer , vol.99 , pp. 1380-1382
    • Billemont, B.1    Medioni, J.2    Taillade, L.3
  • 107
    • 14744281398 scopus 로고    scopus 로고
    • Imatinib and regression of type 2 diabetes
    • Veneri D, Franchini M, Bonora E. Imatinib and regression of type 2 diabetes. N Engl J Med. 2005;352:1049-1050.
    • (2005) N Engl J Med. , vol.352 , pp. 1049-1050
    • Veneri, D.1    Franchini, M.2    Bonora, E.3
  • 108
    • 16544383592 scopus 로고    scopus 로고
    • Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment
    • Breccia M, Muscaritoli M, Aversa Z, Mandelli F, Alimena G Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment. J Clin Oncol. 2004;22:4653-4655.
    • (2004) J Clin Oncol. , vol.22 , pp. 4653-4655
    • Breccia, M.1    Muscaritoli, M.2    Aversa, Z.3    Mandelli, F.4    Alimena, G.5
  • 109
    • 44749094403 scopus 로고    scopus 로고
    • Fasting glucose improvement under dasatinib treatment in an accelerated phase chronic myeloid leukemia patient unresponsive to imatinib and nilotinib
    • Breccia M, Muscaritoli M, Cannella L, Stefanizzi C, Frustaci A, Alimena G. Fasting glucose improvement under dasatinib treatment in an accelerated phase chronic myeloid leukemia patient unresponsive to imatinib and nilotinib. Leuk Res. 2008;32:1626-1628.
    • (2008) Leuk Res. , vol.32 , pp. 1626-1628
    • Breccia, M.1    Muscaritoli, M.2    Cannella, L.3    Stefanizzi, C.4    Frustaci, A.5    Alimena, G.6
  • 110
    • 41549093594 scopus 로고    scopus 로고
    • Remission of diabetes while on sunitinib treatment for renal cell carcinoma
    • Templeton A, Brandle M, Cerny T, Gillessen S. Remission of diabetes while on sunitinib treatment for renal cell carcinoma. Ann Oncol. 2008;19:824-825.
    • (2008) Ann Oncol. , vol.19 , pp. 824-825
    • Templeton, A.1    Brandle, M.2    Cerny, T.3    Gillessen, S.4
  • 111
    • 33745525270 scopus 로고    scopus 로고
    • Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib
    • Hamberg P, de Jong FA, Boonstra JG, van Doorn J, Verweij J, Sleijfer S. Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib. J Clin Oncol. 2006;24:e30-e31.
    • (2006) J Clin Oncol. , vol.24
    • Hamberg, P.1    De Jong, F.A.2    Boonstra, J.G.3    Van Doorn, J.4    Verweij, J.5    Sleijfer, S.6
  • 112
    • 80051560915 scopus 로고    scopus 로고
    • Life-threatening hypoglycemia induced by a tyrosine kinase inhibitor in a patient with neuroendocrine tumor: A case report
    • Lee Y, Jung HS, Choi HJ, et al. Life-threatening hypoglycemia induced by a tyrosine kinase inhibitor in a patient with neuroendocrine tumor: a case report. Diabetes Res Clin Pract. 2011;93: e68-e70.
    • (2011) Diabetes Res Clin Pract. , vol.93
    • Lee, Y.1    Jung, H.S.2    Choi, H.J.3
  • 113
    • 35448996998 scopus 로고    scopus 로고
    • Symptomatic hypoglycemia during imatinib mesylate in a non-diabetic female patient with gastrointestinal stromal tumor
    • Haap M, Gallwitz B, Thamer C, et al. Symptomatic hypoglycemia during imatinib mesylate in a non-diabetic female patient with gastrointestinal stromal tumor. J Endocrinol Invest. 2007;30: 688-692.
    • (2007) J Endocrinol Invest. , vol.30 , pp. 688-692
    • Haap, M.1    Gallwitz, B.2    Thamer, C.3
  • 114
    • 80053339992 scopus 로고    scopus 로고
    • Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice
    • Agostino NM, Chinchilli VM, Lynch CJ, et al. Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice. J Oncol Pharm Pract. 2011;17:197-202.
    • (2011) J Oncol Pharm Pract. , vol.17 , pp. 197-202
    • Agostino, N.M.1    Chinchilli, V.M.2    Lynch, C.J.3
  • 115
    • 57749173855 scopus 로고    scopus 로고
    • Nilotinib: A second-generation tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia
    • Deremer DL, Ustun C, Natarajan K. Nilotinib: a second-generation tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia. Clin Ther. 2008;30:1956-1975.
    • (2008) Clin Ther. , vol.30 , pp. 1956-1975
    • Deremer, D.L.1    Ustun, C.2    Natarajan, K.3
  • 116
    • 84876231431 scopus 로고    scopus 로고
    • Efficacy and safety of nilotinib in chronic phase (CP) chrome myeloid leukemia (CML) patients (Pts) with type 2 diabetes in the ENESTnd Trial
    • December 4-7 Orlando, FL. Abstract 3430
    • Saglio G, Larson RA, Hughes TP, et al. Efficacy and safety of nilotinib in chronic phase (CP) chrome myeloid leukemia (CML) patients (Pts) with type 2 diabetes in the ENESTnd Trial. In: Proceedings from the American Society of Hematology Annual Meeting; December 4-7, 2010; Orlando, FL. Abstract 3430.
    • (2010) Proceedings from the American Society of Hematology Annual Meeting
    • Saglio, G.1    Larson, R.A.2    Hughes, T.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.