KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia

Cell Death and Disease

Volumn 2, Issue 4, 2011, Pages

  Dolga, A M ^a   Terpolilli, N ^b,c   Kepura, F ^a   Nijholt, I M ^d   Knaus, H G ^e   D'Orsi, B ^f   Prehn, J H M ^f   Eisel, U L M ^d   Plant, T ^a   Plesnila, N ^c,f   Culmsee, C ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^f ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

Calcium homeostasis; Cerebral ischemia; Glutamate excitotoxicity; KCa2channels; Neuroprotection

Indexed keywords

APAMIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM ION; GLIBENCLAMIDE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; NS 309; NS 8593; UNCLASSIFIED DRUG; 6,7 DICHLORO 1H INDOLE 2,3 DIONE 3 OXIME; 6,7-DICHLORO-1H-INDOLE-2,3-DIONE 3-OXIME; AMINO ACID RECEPTOR STIMULATING AGENT; INDOLE DERIVATIVE; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT; OXIME; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; DEREGULATION; EXCITOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SINGLE DRUG DOSE; ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; CELL DEATH; CEREBRAL ARTERY DISEASE; CULTURE TECHNIQUE; DRUG EFFECT; DRUG POTENTIATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY;

ANIMALS; BRAIN ISCHEMIA; CALCIUM SIGNALING; CELL CULTURE TECHNIQUES; CELL DEATH; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; GLUTAMIC ACID; INDOLES; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; OXIMES; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; TRANSCRIPTION, GENETIC;

EID: 79960028257     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.30     Document Type: Article

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