-
1
-
-
29144514645
-
Effector memory T cells, early metastasis, and survival in colorectal cancer
-
Pages F, Berger A, Camus M, Sanchez-Cabo F, Costes A, et al. (2005) Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 22: 2654-66.
-
(2005)
N Engl J Med
, vol.22
, pp. 2654-2666
-
-
Pages, F.1
Berger, A.2
Camus, M.3
Sanchez-Cabo, F.4
Costes, A.5
-
2
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, et al. (2006) Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313: 1960-4.
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
Kirilovsky, A.4
Mlecnik, B.5
-
3
-
-
79952093380
-
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction
-
Mlecnik B, Tosolini M, Kirilovsky A, Berger A, Bindea G, et al. (2011) Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction. J Clin Oncol 29: 610-8.
-
(2011)
J Clin Oncol
, vol.29
, pp. 610-618
-
-
Mlecnik, B.1
Tosolini, M.2
Kirilovsky, A.3
Berger, A.4
Bindea, G.5
-
4
-
-
70349423483
-
Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma
-
Sinicrope FA, Rego RL, Ansell SM, Knutson KL, Foster NR, et al. (2009) Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinoma. Gastroenterology 137: 1270-9.
-
(2009)
Gastroenterology
, vol.137
, pp. 1270-1279
-
-
Sinicrope, F.A.1
Rego, R.L.2
Ansell, S.M.3
Knutson, K.L.4
Foster, N.R.5
-
5
-
-
79951815749
-
Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer
-
Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, et al. (2011) Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res 71: 1263-71.
-
(2011)
Cancer Res
, vol.71
, pp. 1263-1271
-
-
Tosolini, M.1
Kirilovsky, A.2
Mlecnik, B.3
Fredriksen, T.4
Mauger, S.5
-
6
-
-
59149107058
-
Pathologic predictors of microsatellite instability in colorectal cancer
-
Greenson JK, Huang SC, Herron C, Moreno V, Bonner JD, et al. (2009) Pathologic predictors of microsatellite instability in colorectal cancer. Am J Surg Pathol 33: 126-33.
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 126-133
-
-
Greenson, J.K.1
Huang, S.C.2
Herron, C.3
Moreno, V.4
Bonner, J.D.5
-
7
-
-
0035875903
-
Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma
-
Smyrk TC, Watson P, Kaul K, Lynch HT, (2001) Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma. Cancer 91: 2417-22.
-
(2001)
Cancer
, vol.91
, pp. 2417-2422
-
-
Smyrk, T.C.1
Watson, P.2
Kaul, K.3
Lynch, H.T.4
-
8
-
-
0035060624
-
Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status
-
Michael-Robinson JM, Biemer-Huttmann A, Purdie DM, Walsh MD, Simms LA, et al. (2001) Tumour infiltrating lymphocytes and apoptosis are independent features in colorectal cancer stratified according to microsatellite instability status. Gut 48: 360-6.
-
(2001)
Gut
, vol.48
, pp. 360-366
-
-
Michael-Robinson, J.M.1
Biemer-Huttmann, A.2
Purdie, D.M.3
Walsh, M.D.4
Simms, L.A.5
-
9
-
-
0034642605
-
Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
-
Gryfe R, Kim H, Hsieh ET, Aronson MD, Holowaty EJ, et al. (2000) Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. N Engl J Med 342: 69-77.
-
(2000)
N Engl J Med
, vol.342
, pp. 69-77
-
-
Gryfe, R.1
Kim, H.2
Hsieh, E.T.3
Aronson, M.D.4
Holowaty, E.J.5
-
10
-
-
28544446428
-
Microsatellite instability and colorectal cancer prognosis
-
Benatti P, Gafà R, Barana D, Marino M, Scarselli A, et al. (2005) Microsatellite instability and colorectal cancer prognosis. Clin Cancer Res 11: 8332-40.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8332-8340
-
-
Benatti, P.1
Gafà, R.2
Barana, D.3
Marino, M.4
Scarselli, A.5
-
11
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
Aaltonen LA, Salovaara R, Kristo P, Canzian F, Hemminki A, et al. (1998) Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med 338: 1481-7.
-
(1998)
N Engl J Med
, vol.338
, pp. 1481-1487
-
-
Aaltonen, L.A.1
Salovaara, R.2
Kristo, P.3
Canzian, F.4
Hemminki, A.5
-
12
-
-
41349097776
-
Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers
-
Schwitalle Y, Kloor M, Eiermann S, Linnebacher M, Kienle P, et al. (2008) Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers. Gastroenterology 134: 988-97.
-
(2008)
Gastroenterology
, vol.134
, pp. 988-997
-
-
Schwitalle, Y.1
Kloor, M.2
Eiermann, S.3
Linnebacher, M.4
Kienle, P.5
-
13
-
-
69549111048
-
Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations
-
Tougeron D, Fauquembergue E, Rouquette A, Le Pessot F, Sesboüé R, et al. (2009) Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations. Mod Pathol 22: 1186-95.
-
(2009)
Mod Pathol
, vol.22
, pp. 1186-1195
-
-
Tougeron, D.1
Fauquembergue, E.2
Rouquette, A.3
Le Pessot, F.4
Sesboüé, R.5
-
14
-
-
5544242524
-
Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
-
Guidoboni M, Gafà R, Viel A, Doglioni C, Russo A, et al. (2001) Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis. Am J Pathol 159: 297-304.
-
(2001)
Am J Pathol
, vol.159
, pp. 297-304
-
-
Guidoboni, M.1
Gafà, R.2
Viel, A.3
Doglioni, C.4
Russo, A.5
-
15
-
-
0033021439
-
High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
-
Dolcetti R, Viel A, Doglioni C, Russo A, Guidoboni M, et al. (1999) High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. Am J Pathol 154: 1805-1813.
-
(1999)
Am J Pathol
, vol.154
, pp. 1805-1813
-
-
Dolcetti, R.1
Viel, A.2
Doglioni, C.3
Russo, A.4
Guidoboni, M.5
-
16
-
-
68449099031
-
Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer
-
Drescher KM, Sharma P, Watson P, Gatalica Z, Thibodeau SN, et al. (2009) Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer. Fam Cancer 8: 231-9.
-
(2009)
Fam Cancer
, vol.8
, pp. 231-239
-
-
Drescher, K.M.1
Sharma, P.2
Watson, P.3
Gatalica, Z.4
Thibodeau, S.N.5
-
17
-
-
1842867040
-
Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic
-
Phillips SM, Banerjea A, Feakins R, Li SR, Bustin SA, et al. (2004) Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic. Br J Surg 91: 469-75.
-
(2004)
Br J Surg
, vol.91
, pp. 469-475
-
-
Phillips, S.M.1
Banerjea, A.2
Feakins, R.3
Li, S.R.4
Bustin, S.A.5
-
18
-
-
44149100809
-
High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas
-
Le Gouvello S, Bastuji-Garin S, Aloulou N, Mansour H, Chaumette MT, et al. (2008) High prevalence of Foxp3 and IL17 in MMR-proficient colorectal carcinomas. Gut 57: 772-9.
-
(2008)
Gut
, vol.57
, pp. 772-779
-
-
Le Gouvello, S.1
Bastuji-Garin, S.2
Aloulou, N.3
Mansour, H.4
Chaumette, M.T.5
-
19
-
-
33846577890
-
Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: a potential role for dysregulation of the transforming growth factor-beta pathway
-
Baker K, Zlobec I, Tornillo L, Terracciano L, Jass JR, et al. (2007) Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: a potential role for dysregulation of the transforming growth factor-beta pathway. Eur J Cancer 43: 624-31.
-
(2007)
Eur J Cancer
, vol.43
, pp. 624-631
-
-
Baker, K.1
Zlobec, I.2
Tornillo, L.3
Terracciano, L.4
Jass, J.R.5
-
20
-
-
33644819186
-
Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors
-
Buhard O, Cattaneo F, Wong YF, Yim SF, Friedman E, et al. (2006) Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors. J Clin Oncol 24: 241-51.
-
(2006)
J Clin Oncol
, vol.24
, pp. 241-251
-
-
Buhard, O.1
Cattaneo, F.2
Wong, Y.F.3
Yim, S.F.4
Friedman, E.5
-
21
-
-
70349968210
-
CD8+ lymphocytes/tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer
-
Lugli A, Karamitopoulou E, Panayiotides I, Karakitsos P, Rallis G, et al. (2009) CD8+ lymphocytes/tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer. Br J Cancer 101: 1382-92.
-
(2009)
Br J Cancer
, vol.101
, pp. 1382-1392
-
-
Lugli, A.1
Karamitopoulou, E.2
Panayiotides, I.3
Karakitsos, P.4
Rallis, G.5
-
22
-
-
0032529466
-
CD8+ T-cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
-
Naito Y, Saito K, Shiiba K, Ohuchi A, Saigenji K, et al. (1998) CD8+ T-cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res 58: 3491-3494.
-
(1998)
Cancer Res
, vol.58
, pp. 3491-3494
-
-
Naito, Y.1
Saito, K.2
Shiiba, K.3
Ohuchi, A.4
Saigenji, K.5
-
23
-
-
3142604756
-
Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability
-
Prall F, Duhrkop T, Weirich V, Ostwald C, Lenz P, et al. (2004) Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability. Hum Pathol 35: 808-16.
-
(2004)
Hum Pathol
, vol.35
, pp. 808-816
-
-
Prall, F.1
Duhrkop, T.2
Weirich, V.3
Ostwald, C.4
Lenz, P.5
-
24
-
-
2342649568
-
The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration
-
Takemoto N, Konishi F, Yamashita K, Kojima M, Furukawa T, et al. (2004) The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration. Jpn J Clin Oncol 34: 90-8.
-
(2004)
Jpn J Clin Oncol
, vol.34
, pp. 90-98
-
-
Takemoto, N.1
Konishi, F.2
Yamashita, K.3
Kojima, M.4
Furukawa, T.5
-
25
-
-
0035500642
-
CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis
-
Radoja S, Saio M, Schaer D, Koneru M, Vukmanovic S, et al. (2001) CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis. J Immunol 167: 5042-51.
-
(2001)
J Immunol
, vol.167
, pp. 5042-5051
-
-
Radoja, S.1
Saio, M.2
Schaer, D.3
Koneru, M.4
Vukmanovic, S.5
-
26
-
-
33748967590
-
Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content
-
Ye SW, Wang Y, Valmori D, Ayyoub M, Han Y, et al. (2006) Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content. J Clin Immunol 26: 447-56.
-
(2006)
J Clin Immunol
, vol.26
, pp. 447-456
-
-
Ye, S.W.1
Wang, Y.2
Valmori, D.3
Ayyoub, M.4
Han, Y.5
-
27
-
-
33751339780
-
Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ
-
Koch M, Beckhove P, Op den Winkel J, Autenrieth D, Wagner P, et al. (2006) Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ. Ann Surg 244: 986-92.
-
(2006)
Ann Surg
, vol.244
, pp. 986-992
-
-
Koch, M.1
Beckhove, P.2
Op den Winkel, J.3
Autenrieth, D.4
Wagner, P.5
-
28
-
-
0038236541
-
Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells
-
Diederichsen AC, Hjelmborg JB, Christensen PB, Zeuthen J, Fenger C, (2003) Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells. Cancer Immunol Immunother 52: 423-8.
-
(2003)
Cancer Immunol Immunother
, vol.52
, pp. 423-428
-
-
Diederichsen, A.C.1
Hjelmborg, J.B.2
Christensen, P.B.3
Zeuthen, J.4
Fenger, C.5
-
29
-
-
68949204170
-
T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases
-
Katz SC, Pillarisetty V, Bamboat ZM, Shia J, Hedvat C, et al. (2009) T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases. Ann Surg Oncol 16: 2524-30.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2524-2530
-
-
Katz, S.C.1
Pillarisetty, V.2
Bamboat, Z.M.3
Shia, J.4
Hedvat, C.5
-
30
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
von Boehmer H, (2005) Mechanisms of suppression by suppressor T cells. Nat Immunol 6: 338-44.
-
(2005)
Nat Immunol
, vol.6
, pp. 338-344
-
-
von Boehmer, H.1
-
31
-
-
54949139152
-
CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer
-
Clarke SL, Betts GJ, Plant A, Wright KL, El-Shanawany TM, et al. (2006) CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer. PLoS One 1: e129.
-
(2006)
PLoS One
, vol.1
-
-
Clarke, S.L.1
Betts, G.J.2
Plant, A.3
Wright, K.L.4
El-Shanawany, T.M.5
-
32
-
-
85044706836
-
Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients
-
Ling KL, Pratap SE, Bates GJ, Singh B, Mortensen NJ, et al. (2007) Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients. Cancer Immun 28: 7.
-
(2007)
Cancer Immun
, vol.28
, pp. 7
-
-
Ling, K.L.1
Pratap, S.E.2
Bates, G.J.3
Singh, B.4
Mortensen, N.J.5
-
33
-
-
38849156068
-
In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer
-
Loddenkemper C, Schernus M, Noutsias M, Stein H, Thiel E, et al. (2006) In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer. J Transl Med 4: 52.
-
(2006)
J Transl Med
, vol.4
, pp. 52
-
-
Loddenkemper, C.1
Schernus, M.2
Noutsias, M.3
Stein, H.4
Thiel, E.5
-
34
-
-
63849224217
-
Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue
-
Chaput N, Louafi S, Bardier A, Charlotte F, Vaillant JC, et al. (2009) Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue. Gut 58: 520-9.
-
(2009)
Gut
, vol.58
, pp. 520-529
-
-
Chaput, N.1
Louafi, S.2
Bardier, A.3
Charlotte, F.4
Vaillant, J.C.5
-
35
-
-
58249089749
-
Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
-
Salama P, Phillips M, Grieu F, Morris M, Zeps N, et al. (2009) Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 27: 186-92.
-
(2009)
J Clin Oncol
, vol.27
, pp. 186-192
-
-
Salama, P.1
Phillips, M.2
Grieu, F.3
Morris, M.4
Zeps, N.5
-
36
-
-
77951217044
-
High frequency of tumor infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients
-
Frey DM, Droeser RA, Viehl CT, Zlobec I, Lugli A, et al. (2009) High frequency of tumor infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients. Int J Cancer 126: 2635-2643.
-
(2009)
Int J Cancer
, vol.126
, pp. 2635-2643
-
-
Frey, D.M.1
Droeser, R.A.2
Viehl, C.T.3
Zlobec, I.4
Lugli, A.5
-
37
-
-
78349277576
-
Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review
-
Nosho K, Baba Y, Tanaka N, Shima K, Hayashi M, et al. (2010) Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review. J Pathol 222: 350-66.
-
(2010)
J Pathol
, vol.222
, pp. 350-366
-
-
Nosho, K.1
Baba, Y.2
Tanaka, N.3
Shima, K.4
Hayashi, M.5
-
38
-
-
77954753615
-
Lack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes
-
Michel S, Linnebacher M, Alcaniz J, Voss M, Wagner R, et al. (2010) Lack of HLA class II antigen expression in microsatellite unstable colorectal carcinomas is caused by mutations in HLA class II regulatory genes. Int J Cancer 127: 889-98.
-
(2010)
Int J Cancer
, vol.127
, pp. 889-898
-
-
Michel, S.1
Linnebacher, M.2
Alcaniz, J.3
Voss, M.4
Wagner, R.5
-
39
-
-
77950825019
-
Molecular pathways and targets in cancer-related inflammation
-
Mantovani A, Garlanda C, Allavena P, (2010) Molecular pathways and targets in cancer-related inflammation. Ann Med 42: 161-70.
-
(2010)
Ann Med
, vol.42
, pp. 161-170
-
-
Mantovani, A.1
Garlanda, C.2
Allavena, P.3
-
40
-
-
84879401216
-
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer
-
Blatner NR, Mulcahy MF, Dennis KL, Scholtens D, Bentrem DJ, et al. (2012) Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer. Sci Transl Med 4: 164-159.
-
(2012)
Sci Transl Med
, vol.4
, pp. 159-164
-
-
Blatner, N.R.1
Mulcahy, M.F.2
Dennis, K.L.3
Scholtens, D.4
Bentrem, D.J.5
-
41
-
-
0034611854
-
Comparison on fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial
-
QUASAR Collaborative Group
-
QUASAR Collaborative Group (2000) Comparison on fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial. Lancet 355: 1588-1596.
-
(2000)
Lancet
, vol.355
, pp. 1588-1596
-
-
|