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Volumn 43, Issue 3, 2007, Pages 624-631

Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: A potential role for dysregulation of the transforming growth factor-β pathway

Author keywords

Colorectal cancer; Intraepithelial lymphocytes; Mismatch repair; Transforming growth factor ; Tumour infiltrating lymphocytes

Indexed keywords

KI 67 ANTIGEN; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 33846577890     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2006.11.012     Document Type: Article
Times cited : (55)

References (30)
  • 2
    • 5544242524 scopus 로고    scopus 로고
    • Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
    • Guidoboni M., Gafa R., Viel A., et al. Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis. Am J Pathol 159 1 (2001) 297-304
    • (2001) Am J Pathol , vol.159 , Issue.1 , pp. 297-304
    • Guidoboni, M.1    Gafa, R.2    Viel, A.3
  • 3
    • 12244294056 scopus 로고    scopus 로고
    • CD103+ intraepithelial lymphocytes - a unique population in microsatellite unstable sporadic colorectal cancer
    • Quinn E., Hawkins N., Yip Y.L., Suter C., and Ward R. CD103+ intraepithelial lymphocytes - a unique population in microsatellite unstable sporadic colorectal cancer. Eur J Cancer 39 4 (2003) 469-475
    • (2003) Eur J Cancer , vol.39 , Issue.4 , pp. 469-475
    • Quinn, E.1    Hawkins, N.2    Yip, Y.L.3    Suter, C.4    Ward, R.5
  • 4
    • 0034869813 scopus 로고    scopus 로고
    • Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease
    • Di Sabatino A., Ciccocioppo R., D'Alo S., et al. Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease. Gut 49 3 (2001) 380-386
    • (2001) Gut , vol.49 , Issue.3 , pp. 380-386
    • Di Sabatino, A.1    Ciccocioppo, R.2    D'Alo, S.3
  • 5
    • 0027522465 scopus 로고
    • Lymphokine-activated killing by human intestinal lymphocytes
    • Ebert E.C., and Roberts A.I. Lymphokine-activated killing by human intestinal lymphocytes. Cell Immunol 146 1 (1993) 107-116
    • (1993) Cell Immunol , vol.146 , Issue.1 , pp. 107-116
    • Ebert, E.C.1    Roberts, A.I.2
  • 6
    • 2342649568 scopus 로고    scopus 로고
    • The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration
    • Takemoto N., Konishi F., Yamashita K., et al. The correlation of microsatellite instability and tumor-infiltrating lymphocytes in hereditary non-polyposis colorectal cancer (HNPCC) and sporadic colorectal cancers: the significance of different types of lymphocyte infiltration. Jpn J Clin Oncol 34 2 (2004) 90-98
    • (2004) Jpn J Clin Oncol , vol.34 , Issue.2 , pp. 90-98
    • Takemoto, N.1    Konishi, F.2    Yamashita, K.3
  • 7
    • 0033021439 scopus 로고    scopus 로고
    • High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
    • Dolcetti R., Viel A., Doglioni C., et al. High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. Am J Pathol 154 6 (1999) 1805-1813
    • (1999) Am J Pathol , vol.154 , Issue.6 , pp. 1805-1813
    • Dolcetti, R.1    Viel, A.2    Doglioni, C.3
  • 8
    • 0141815907 scopus 로고    scopus 로고
    • Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability
    • Ishikawa T., Fujita T., Suzuki Y., et al. Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability. Cancer Res 63 17 (2003) 5564-5572
    • (2003) Cancer Res , vol.63 , Issue.17 , pp. 5564-5572
    • Ishikawa, T.1    Fujita, T.2    Suzuki, Y.3
  • 9
    • 27444445519 scopus 로고    scopus 로고
    • The immunogenicity of colorectal cancers with high-degree microsatellite instability
    • Banerjea A., Bustin S.A., and Dorudi S. The immunogenicity of colorectal cancers with high-degree microsatellite instability. World J Surg Oncol 3 (2005) 26
    • (2005) World J Surg Oncol , vol.3 , pp. 26
    • Banerjea, A.1    Bustin, S.A.2    Dorudi, S.3
  • 10
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz S., Wang J., Myeroff L., et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 268 5215 (1995) 1336-1338
    • (1995) Science , vol.268 , Issue.5215 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3
  • 11
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R., and Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425 6958 (2003) 577-584
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 12
    • 0034023127 scopus 로고    scopus 로고
    • Role of Ras and Mapks in TGFbeta signaling
    • Mulder K.M. Role of Ras and Mapks in TGFbeta signaling. Cytokine Growth Factor Rev 11 1-2 (2000) 23-35
    • (2000) Cytokine Growth Factor Rev , vol.11 , Issue.1-2 , pp. 23-35
    • Mulder, K.M.1
  • 13
    • 33748754842 scopus 로고    scopus 로고
    • Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes
    • Baker K., Chong G., Foulkes W.D., and Jass J.R. Transforming growth factor-beta pathway disruption and infiltration of colorectal cancers by intraepithelial lymphocytes. Histopathology 49 4 (2006) 371-380
    • (2006) Histopathology , vol.49 , Issue.4 , pp. 371-380
    • Baker, K.1    Chong, G.2    Foulkes, W.D.3    Jass, J.R.4
  • 14
    • 0346958238 scopus 로고    scopus 로고
    • Tissue microarrays in drug discovery
    • Sauter G., Simon R., and Hillan K. Tissue microarrays in drug discovery. Nat Rev Drug Discov 2 12 (2003) 962-972
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.12 , pp. 962-972
    • Sauter, G.1    Simon, R.2    Hillan, K.3
  • 15
    • 33748846786 scopus 로고    scopus 로고
    • Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer
    • Lugli A., Zlobec I., Gunthert U., et al. Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancer. Mod Pathol 19 10 (2006) 1302-1309
    • (2006) Mod Pathol , vol.19 , Issue.10 , pp. 1302-1309
    • Lugli, A.1    Zlobec, I.2    Gunthert, U.3
  • 16
    • 33746073328 scopus 로고    scopus 로고
    • Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer - a tissue microarray-based approach
    • Lugli A., Zlobec I., Minoo P., et al. Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer - a tissue microarray-based approach. Hum Pathol 37 8 (2006) 1022-1031
    • (2006) Hum Pathol , vol.37 , Issue.8 , pp. 1022-1031
    • Lugli, A.1    Zlobec, I.2    Minoo, P.3
  • 17
    • 23244443650 scopus 로고    scopus 로고
    • Cancer risk in hereditary nonpolyposis colorectal cancer syndrome: later age of onset
    • Hampel H., Stephens J.A. Pukkala E., et al. Cancer risk in hereditary nonpolyposis colorectal cancer syndrome: later age of onset. Gastroenterology 129 2 (2005) 415-421
    • (2005) Gastroenterology , vol.129 , Issue.2 , pp. 415-421
    • Hampel, H.1    Stephens, J.A.2    Pukkala, E.3
  • 18
    • 0024443297 scopus 로고
    • Receiver operating characteristic (ROC) methodology: the state of the art
    • Hanley J.A. Receiver operating characteristic (ROC) methodology: the state of the art. Crit Rev Diagn Imaging 29 3 (1989) 307-335
    • (1989) Crit Rev Diagn Imaging , vol.29 , Issue.3 , pp. 307-335
    • Hanley, J.A.1
  • 20
    • 29144514645 scopus 로고    scopus 로고
    • Effector memory T cells, early metastasis, and survival in colorectal cancer
    • Pages F., Berger A., Camus M., et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. New Engl J Med 353 25 (2005) 2654-2666
    • (2005) New Engl J Med , vol.353 , Issue.25 , pp. 2654-2666
    • Pages, F.1    Berger, A.2    Camus, M.3
  • 21
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J., Costes A., Sanchez-Cabo F., et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313 5795 (2006) 1960-1964
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 22
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn G.P., Old L.J., and Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21 2 (2004) 137-148
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 23
    • 0032547272 scopus 로고    scopus 로고
    • Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members
    • Afrakhte M., Moren A., Jossan S., et al. Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members. Biochem Biophys Res Commun 249 2 (1998) 505-511
    • (1998) Biochem Biophys Res Commun , vol.249 , Issue.2 , pp. 505-511
    • Afrakhte, M.1    Moren, A.2    Jossan, S.3
  • 24
    • 0344026339 scopus 로고    scopus 로고
    • M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1
    • Godar S., Horejsi V., Weidle U.H., et al. M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1. Eur J Immunol 29 3 (1999) 1004-1013
    • (1999) Eur J Immunol , vol.29 , Issue.3 , pp. 1004-1013
    • Godar, S.1    Horejsi, V.2    Weidle, U.H.3
  • 25
    • 0035006032 scopus 로고    scopus 로고
    • Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103)
    • Robinson P.W., Green S.J., Carter C., Coadwell J., and Kilshaw P.J. Studies on transcriptional regulation of the mucosal T-cell integrin alphaEbeta7 (CD103). Immunology 103 2 (2001) 146-154
    • (2001) Immunology , vol.103 , Issue.2 , pp. 146-154
    • Robinson, P.W.1    Green, S.J.2    Carter, C.3    Coadwell, J.4    Kilshaw, P.J.5
  • 26
    • 0029804205 scopus 로고    scopus 로고
    • Identification of a binding site for integrin alphaEbeta7 in the N-terminal domain of E-cadherin
    • Karecla P.I., Green S.J., Bowden S.J., Coadwell J., and Kilshaw P.J. Identification of a binding site for integrin alphaEbeta7 in the N-terminal domain of E-cadherin. J Biol Chem 271 48 (1996) 30909-30915
    • (1996) J Biol Chem , vol.271 , Issue.48 , pp. 30909-30915
    • Karecla, P.I.1    Green, S.J.2    Bowden, S.J.3    Coadwell, J.4    Kilshaw, P.J.5
  • 27
    • 0001360371 scopus 로고
    • Regulation of intestinal epithelial cell growth by transforming growth factor type beta
    • Barnard J.A., Beauchamp R.D., Coffey R.J., and Moses H.L. Regulation of intestinal epithelial cell growth by transforming growth factor type beta. Proc Natl Acad Sci USA 86 5 (1989) 1578-1582
    • (1989) Proc Natl Acad Sci USA , vol.86 , Issue.5 , pp. 1578-1582
    • Barnard, J.A.1    Beauchamp, R.D.2    Coffey, R.J.3    Moses, H.L.4
  • 28
    • 2442492933 scopus 로고    scopus 로고
    • Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1
    • Wan M., Tang Y., Tytler E.M., et al. Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1. J Biol Chem 279 15 (2004) 14484-14487
    • (2004) J Biol Chem , vol.279 , Issue.15 , pp. 14484-14487
    • Wan, M.1    Tang, Y.2    Tytler, E.M.3
  • 29
    • 0035861541 scopus 로고    scopus 로고
    • Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity
    • Bhowmick N.A., Zent R., Ghiassi M., McDonnell M., and Moses H.L. Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. J Biol Chem 276 50 (2001) 46707-46713
    • (2001) J Biol Chem , vol.276 , Issue.50 , pp. 46707-46713
    • Bhowmick, N.A.1    Zent, R.2    Ghiassi, M.3    McDonnell, M.4    Moses, H.L.5
  • 30
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R., Akhurst R.J., and Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 29 2 (2001) 117-129
    • (2001) Nat Genet , vol.29 , Issue.2 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.