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Volumn 22, Issue 8, 2013, Pages 1177-1189

Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation

Author keywords

[No Author keywords available]

Indexed keywords

GEMININ; SHORT HAIRPIN RNA; UVOMORULIN; WNT PROTEIN;

EID: 84876146942     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0050     Document Type: Article
Times cited : (10)

References (78)
  • 1
    • 18344381110 scopus 로고    scopus 로고
    • Cell cycle in mouse development
    • Ciemerych MA and P Sicinski. (2005). Cell cycle in mouse development. Oncogene 24:2877-2898.
    • (2005) Oncogene , vol.24 , pp. 2877-2898
    • Ciemerych, M.A.1    Sicinski, P.2
  • 3
    • 0036709213 scopus 로고    scopus 로고
    • Signalling, cell cycle and pluripotency in embryonic stem cells
    • Burdon T, A Smith and P Savatier. (2002). Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 12:432-438.
    • (2002) Trends Cell Biol , vol.12 , pp. 432-438
    • Burdon, T.1    Smith, A.2    Savatier, P.3
  • 4
    • 16344375767 scopus 로고    scopus 로고
    • Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation
    • White J, E Stead, R Faast, S Conn, P Cartwright and S Dalton. (2005). Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell 16:2018-2027.
    • (2005) Mol Biol Cell , vol.16 , pp. 2018-2027
    • White, J.1    Stead, E.2    Faast, R.3    Conn, S.4    Cartwright, P.5    Dalton, S.6
  • 5
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ and MH Kaufman. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 6
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 78: 7634-7638.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 7
    • 0032511148 scopus 로고    scopus 로고
    • Geminin, an inhibitor of DNA replication, is degraded during mitosis
    • McGarry TJ and MW Kirschner. 1998. Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 93: 1043-1053.
    • (1998) Cell , vol.93 , pp. 1043-1053
    • McGarry, T.J.1    Kirschner, M.W.2
  • 9
    • 13244259164 scopus 로고    scopus 로고
    • Geminin coordinates cell cycle and developmental control
    • Luo L and M Kessel. (2004). Geminin coordinates cell cycle and developmental control. Cell Cycle 3:711-714.
    • (2004) Cell Cycle , vol.3 , pp. 711-714
    • Luo, L.1    Kessel, M.2
  • 10
    • 0036313608 scopus 로고    scopus 로고
    • Expression of geminin as a marker of cell proliferation in normal tissues and malignancies
    • Wohlschlegel JA, JL Kutok, AP Weng and A Dutta. (2002). Expression of geminin as a marker of cell proliferation in normal tissues and malignancies. Am J Pathol 161:267-273.
    • (2002) Am J Pathol , vol.161 , pp. 267-273
    • Wohlschlegel, J.A.1    Kutok, J.L.2    Weng, A.P.3    Dutta, A.4
  • 12
    • 33750142817 scopus 로고    scopus 로고
    • Geminin is essential for the development of preimplantation mouse embryos
    • Hara K, KI Nakayama and K Nakayama. (2006). Geminin is essential for the development of preimplantation mouse embryos. Genes Cells 11:1281-1293.
    • (2006) Genes Cells , vol.11 , pp. 1281-1293
    • Hara, K.1    Nakayama, K.I.2    Nakayama, K.3
  • 13
    • 30044450747 scopus 로고    scopus 로고
    • Tcf- and Ventbinding sites regulate neural-specific geminin expression in the gastrula embryo
    • Taylor JJ, T Wang and KL Kroll. (2006). Tcf- and Ventbinding sites regulate neural-specific geminin expression in the gastrula embryo. Dev Biol 289:494-506.
    • (2006) Dev Biol , vol.289 , pp. 494-506
    • Taylor, J.J.1    Wang, T.2    Kroll, K.L.3
  • 14
    • 78650744015 scopus 로고    scopus 로고
    • Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo
    • Lim JW, P Hummert, JC Mills and KL Kroll. (2011). Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo. Development 138:33-44.
    • (2011) Development , vol.138 , pp. 33-44
    • Lim, J.W.1    Hummert, P.2    Mills, J.C.3    Kroll, K.L.4
  • 15
    • 0035312290 scopus 로고    scopus 로고
    • All Tcf HMG box transcription factors interact with Groucho-related co-repressors
    • Brantjes H, J Roose, M van De Wetering and H Clevers. (2001). All Tcf HMG box transcription factors interact with Groucho-related co-repressors. Nucleic Acids Res 29:1410-1419.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1410-1419
    • Brantjes, H.1    Roose, J.2    Wetering De M.Van3    Clevers, H.4
  • 16
    • 33749509017 scopus 로고    scopus 로고
    • Transplacental RNAi: Deciphering gene function in the postimplantation-staged embryo
    • O'Shea KS, LS De Boer, NA Slawny and TE Gratsch. (2006). Transplacental RNAi: Deciphering gene function in the postimplantation-staged embryo. J Biomed Biotechnol 2006:18657.
    • (2006) J Biomed Biotechnol , vol.2006 , pp. 18657
    • O'Shea, K.S.1    De Boer, L.S.2    Slawny, N.A.3    Gratsch, T.E.4
  • 17
    • 26644472432 scopus 로고    scopus 로고
    • An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit
    • Masui S, D Shimosato, Y Toyooka, R Yagi, K Takahashi and H Niwa. (2005). An efficient system to establish multiple embryonic stem cell lines carrying an inducible expression unit. Nucleic Acids Res 33:e43.
    • (2005) Nucleic Acids Res , vol.33
    • Masui, S.1    Shimosato, D.2    Toyooka, Y.3    Yagi, R.4    Takahashi, K.5    Niwa, H.6
  • 18
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in realtime PCR
    • Pfaffl MW, GW Horgan and L Dempfle. (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in realtime PCR. Nucleic Acids Res 30:e36.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 19
    • 79251631666 scopus 로고    scopus 로고
    • Tetracycline compounds with non-antimicrobial organ protective properties: Possible mechanisms of action
    • Griffin MO, G Ceballos and FJ Villarreal. (2011). Tetracycline compounds with non-antimicrobial organ protective properties: Possible mechanisms of action. Pharmacol Res 63: 102-107.
    • (2011) Pharmacol Res , vol.63 , pp. 102-107
    • Griffin, M.O.1    Ceballos, G.2    Villarreal, F.J.3
  • 20
    • 84865724109 scopus 로고    scopus 로고
    • Geminin is required for epithelial to mesenchymal transition at gastrulation
    • Emmett LS and O'Shea KS. (2012). Geminin is required for epithelial to mesenchymal transition at gastrulation. Stem Cells Dev 21:2395-2409.
    • (2012) Stem Cells Dev , vol.21 , pp. 2395-2409
    • Emmett, L.S.1    O'Shea, K.S.2
  • 21
    • 26444491715 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thyminerich insulin response element
    • Finlay D, S Patel, LM Dickson, N Shpiro, R Marquez, CJ Rhodes and C Sutherland. (2004). Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thyminerich insulin response element. BMC Mol Biol 5:15.
    • (2004) BMC Mol Biol , vol.5 , pp. 15
    • Finlay, D.1    Patel, S.2    Dickson, L.M.3    Shpiro, N.4    Marquez, R.5    Rhodes, C.J.6    Sutherland, C.7
  • 22
    • 33644661116 scopus 로고    scopus 로고
    • Regulation of axin2 expression at the levels of transcription, translation and protein stability in lung and colon cancer
    • Hughes TA and HJ Brady. (2006). Regulation of axin2 expression at the levels of transcription, translation and protein stability in lung and colon cancer. Cancer Lett 233: 338-347.
    • (2006) Cancer Lett , vol.233 , pp. 338-347
    • Hughes, T.A.1    Brady, H.J.2
  • 23
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, T Zhang, C Domon, CK Joo, JN Freund and F Costantini. (2002). Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 22:1172-1183.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 24
    • 0037077266 scopus 로고    scopus 로고
    • Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling
    • Leung JY, FT Kolligs, R Wu, Y Zhai, R Kuick, S Hanash, KR Cho and ER Fearon. (2002). Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. J Biol Chem 277:21657-21665.
    • (2002) J Biol Chem , vol.277 , pp. 21657-21665
    • Leung, J.Y.1    Kolligs, F.T.2    Wu, R.3    Zhai, Y.4    Kuick, R.5    Hanash, S.6    Cho, K.R.7    Fearon, E.R.8
  • 26
    • 0035887012 scopus 로고    scopus 로고
    • The Drosophila Geminin homolog: Roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis
    • Quinn LM, A Herr, TJ McGarry and H Richardson. (2001). The Drosophila Geminin homolog: Roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis. Genes Dev 15:2741-2754.
    • (2001) Genes Dev , vol.15 , pp. 2741-2754
    • Quinn, L.M.1    Herr, A.2    McGarry, T.J.3    Richardson, H.4
  • 27
    • 79955481540 scopus 로고    scopus 로고
    • Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog
    • Yang VS, SA Carter, SJ Hyland, K Tachibana-Konwalski, RA Laskey and MA Gonzalez. (2011). Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog. Curr Biol 21: 692-699.
    • (2011) Curr Biol , vol.21 , pp. 692-699
    • Yang, V.S.1    Carter, S.A.2    Hyland, S.J.3    Tachibana-Konwalski, K.4    Laskey, R.A.5    Gonzalez, M.A.6
  • 28
    • 79952768015 scopus 로고    scopus 로고
    • Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state
    • Yellajoshyula D, ES Patterson, MS Elitt and KL Kroll. (2011). Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state. Proc Natl Acad Sci U S A 108:3294-3299.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3294-3299
    • Yellajoshyula, D.1    Patterson, E.S.2    Elitt, M.S.3    Kroll, K.L.4
  • 32
  • 33
    • 1442305333 scopus 로고    scopus 로고
    • The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions
    • Luo L, X Yang, Y Takihara, H Knoetgen and M Kessel. (2004). The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions. Nature 427:749-753.
    • (2004) Nature , vol.427 , pp. 749-753
    • Luo, L.1    Yang, X.2    Takihara, Y.3    Knoetgen, H.4    Kessel, M.5
  • 34
    • 1442354189 scopus 로고    scopus 로고
    • Direct interaction of geminin and Six3 in eye development
    • Del Bene F, K Tessmar-Raible and J Wittbrodt. (2004). Direct interaction of geminin and Six3 in eye development. Nature 427:745-749.
    • (2004) Nature , vol.427 , pp. 745-749
    • Del Bene, F.1    Tessmar-Raible, K.2    Wittbrodt, J.3
  • 35
    • 21544432166 scopus 로고    scopus 로고
    • The regulation of embryonic patterning and DNA replication by geminin
    • Pitulescu M, M Kessel and L Luo. (2005). The regulation of embryonic patterning and DNA replication by geminin. Cell Mol Life Sci 62:1425-1433.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 1425-1433
    • Pitulescu, M.1    Kessel, M.2    Luo, L.3
  • 36
    • 18744400798 scopus 로고    scopus 로고
    • Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wntmediated transcription activation
    • Daniels DL and WI Weiss. (2005). Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wntmediated transcription activation. Nat Struct Mol Biol 12:364-371.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 364-371
    • Daniels, D.L.1    Weiss, W.I.2
  • 37
    • 44349150869 scopus 로고    scopus 로고
    • Novel TCF-binding sites specify transcriptional repression by Wnt signalling
    • Blauwkamp TA, MV Chang and KM Cadigan. (2008). Novel TCF-binding sites specify transcriptional repression by Wnt signalling. EMBO J 27:1436-1446.
    • (2008) EMBO J , vol.27 , pp. 1436-1446
    • Blauwkamp, T.A.1    Chang, M.V.2    Cadigan, K.M.3
  • 38
    • 2342441840 scopus 로고    scopus 로고
    • The Wnt coreceptors Lrp5 and Lrp6 are essential for gastrulation in mice
    • Kelly OG, KI Pinson and WC Skarnes. (2004). The Wnt coreceptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development 131:2803-2815.
    • (2004) Development , vol.131 , pp. 2803-2815
    • Kelly, O.G.1    Pinson, K.I.2    Skarnes, W.C.3
  • 40
    • 64049103079 scopus 로고    scopus 로고
    • NFkappaB and Snail1a coordinate the cell cycle with gastrulation
    • Liu X, S Huang, J Ma, C Li, Y Zhang and L Luo. (2009). NFkappaB and Snail1a coordinate the cell cycle with gastrulation. J Cell Biol 184:805-815.
    • (2009) J Cell Biol , vol.184 , pp. 805-815
    • Liu, X.1    Huang, S.2    Ma., J.3    Li., C.4    Zhang, Y.5    Luo, L.6
  • 42
    • 4544308625 scopus 로고    scopus 로고
    • Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo
    • Mohamed OA, HJ Clarke and D Dufort. (2004). Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo. Dev Dyn 231:416-424.
    • (2004) Dev Dyn , vol.231 , pp. 416-424
    • Mohamed, O.A.1    Clarke, H.J.2    Dufort, D.3
  • 43
    • 29044447949 scopus 로고    scopus 로고
    • Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3
    • Rivera-Perez JA and T Magnuson. (2005). Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3. Dev Biol 288:363-371.
    • (2005) Dev Biol , vol.288 , pp. 363-371
    • Rivera-Perez, J.A.1    Magnuson, T.2
  • 44
    • 0035167812 scopus 로고    scopus 로고
    • The mouse snail gene encodes a key regulator of the epithelial- mesenchymal transition
    • Carver EA, R Jiang, Y Lan, KF Oram and T Gridley. (2001). The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol 21:8184-8188.
    • (2001) Mol Cell Biol , vol.21 , pp. 8184-8188
    • Carver, E.A.1    Jiang, R.2    Lan, Y.3    Oram, K.F.4    Gridley, T.5
  • 45
    • 0028318730 scopus 로고
    • Control of cell behavior during vertebrate development by Slug, a zinc finger gene
    • Nieto MA, MG Sargent, DG Wilkinson and J Cooke. (1994). Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264:835-839.
    • (1994) Science , vol.264 , pp. 835-839
    • Nieto, M.A.1    Sargent, M.G.2    Wilkinson, D.G.3    Cooke, J.4
  • 46
    • 58149316623 scopus 로고    scopus 로고
    • Snail and Slug promote epithelial-mesenchymal transition through betacatenin-T-cell factor-4-dependent expression of transforming growth factor-beta3
    • Medici D, ED Hay and BR Olsen. (2008). Snail and Slug promote epithelial-mesenchymal transition through betacatenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell 19:4875-4887.
    • (2008) Mol Biol Cell , vol.19 , pp. 4875-4887
    • Medici, D.1    Hay, E.D.2    Olsen, B.R.3
  • 47
    • 50649103964 scopus 로고    scopus 로고
    • Snail promotes Wnt target gene expression and interacts with beta-catenin
    • Stemmer V, B de Craene, G Berx and J Behrens. (2008). Snail promotes Wnt target gene expression and interacts with beta-catenin. Oncogene 27:5075-5080.
    • (2008) Oncogene , vol.27 , pp. 5075-5080
    • Stemmer, V.1    De Craene, B.2    Berx, G.3    Behrens, J.4
  • 48
    • 12144266241 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: Implications for the epithelial-mesenchymal transition
    • Bachelder RE, SO Yoon, C Franci, AG de Herreros and AM Mercurio. (2005). Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: Implications for the epithelial-mesenchymal transition. J Cell Biol 168: 29-33.
    • (2005) J Cell Biol , vol.168 , pp. 29-33
    • Bachelder, R.E.1    Yoon, S.O.2    Franci, C.3    De Herreros, A.G.4    Mercurio, A.M.5
  • 49
    • 33751248737 scopus 로고    scopus 로고
    • Snail1 gene function during early embryo patterning in mice
    • Murray SA and T Gridley. (2006). Snail1 gene function during early embryo patterning in mice. Cell Cycle 5:2566-2570.
    • (2006) Cell Cycle , vol.5 , pp. 2566-2570
    • Murray, S.A.1    Gridley, T.2
  • 50
    • 27744550696 scopus 로고    scopus 로고
    • Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling
    • Sakai D, Y Tanaka, Y Endo, N Osumi, H Okamoto and Y Wakamatsu. (2005). Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling. Dev Growth Differ 47:471-482.
    • (2005) Dev Growth Differ , vol.47 , pp. 471-482
    • Sakai, D.1    Tanaka, Y.2    Endo, Y.3    Osumi, N.4    Okamoto, H.5    Wakamatsu, Y.6
  • 52
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou BP, J Deng, W Xia, J Xu, YM Li, M Gunduz and MC Hung. (2004). Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6:931-940.
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 53
    • 4644360723 scopus 로고    scopus 로고
    • Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity
    • Chesnutt C, LW Burrus, AM Brown and L Niswander. (2004). Coordinate regulation of neural tube patterning and proliferation by TGFbeta and WNT activity. Dev Biol 274: 334-347.
    • (2004) Dev Biol , vol.274 , pp. 334-347
    • Chesnutt, C.1    Burrus, L.W.2    Brown, A.M.3    Niswander, L.4
  • 54
    • 1642377931 scopus 로고    scopus 로고
    • The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells
    • Israsena N, M Hu, W Fu, L Kan and JA Kessler. (2004). The presence of FGF2 signaling determines whether beta-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. Dev Biol 268:220-231.
    • (2004) Dev Biol , vol.268 , pp. 220-231
    • Israsena, N.1    Hu., M.2    Fu, W.3    Kan, L.4    Kessler, J.A.5
  • 56
    • 0038517899 scopus 로고    scopus 로고
    • Beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system
    • Zechner D, Y Fujita, J Hulsken, T Muller, I Walther, MM Taketo, EB Crenshaw, 3rd, W Birchmeier and C Birchmeier. (2003). beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol 258:406-418.
    • (2003) Dev Biol , vol.258 , pp. 406-418
    • Zechner, D.1    Fujita, Y.2    Hulsken, J.3    Muller, T.4    Walther, I.5    Taketo, M.M.6    Crenshaw, E.B.7    Birchmeier, W.8    Birchmeier, C.9
  • 57
    • 3242889925 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells
    • Hirabayashi Y, Y Itoh, H Tabata, K Nakajima, T Akiyama, N Masuyama and Y Gotoh. (2004). The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 131:2791-2801.
    • (2004) Development , vol.131 , pp. 2791-2801
    • Hirabayashi, Y.1    Itoh, Y.2    Tabata, H.3    Nakajima, K.4    Akiyama, T.5    Masuyama, N.6    Gotoh, Y.7
  • 58
    • 0036499974 scopus 로고    scopus 로고
    • Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord
    • Muroyama Y, M Fujihara, M Ikeya, H Kondoh and S Takada. (2002). Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev 16:548-553.
    • (2002) Genes Dev , vol.16 , pp. 548-553
    • Muroyama, Y.1    Fujihara, M.2    Ikeya, M.3    Kondoh, H.4    Takada, S.5
  • 59
    • 17844366846 scopus 로고    scopus 로고
    • WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
    • Ciani L and PC Salinas. (2005). WNTs in the vertebrate nervous system: From patterning to neuronal connectivity. Nat Rev Neurosci 6:351-362.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 351-362
    • Ciani, L.1    Salinas, P.C.2
  • 60
    • 0036274515 scopus 로고    scopus 로고
    • Progressive induction of caudal neural character by graded Wnt signaling
    • Nordstrom U, TM Jessell and T Edlund. (2002). Progressive induction of caudal neural character by graded Wnt signaling. Nat Neurosci 5:525-532.
    • (2002) Nat Neurosci , vol.5 , pp. 525-532
    • Nordstrom, U.1    Jessell, T.M.2    Edlund, T.3
  • 62
    • 80053384049 scopus 로고    scopus 로고
    • Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells
    • Slawny NA and KS O'Shea. (2011). Dynamic changes in Wnt signaling are required for neuronal differentiation of mouse embryonic stem cells. Mol Cell Neurosci 48:205-216.
    • (2011) Mol Cell Neurosci , vol.48 , pp. 205-216
    • Slawny, N.A.1    O'Shea, K.S.2
  • 63
    • 33750936779 scopus 로고    scopus 로고
    • Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
    • Gadue P, TL Huber, PJ Paddison and GM Keller. (2006). Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc Natl Acad Sci U S A 103:16806-16811.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 16806-16811
    • Gadue, P.1    Huber, T.L.2    Paddison, P.J.3    Keller, G.M.4
  • 64
    • 33750442483 scopus 로고    scopus 로고
    • Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm
    • Lindsley RC, JG Gill, M Kyba, TL Murphy and KM Murphy. (2006). Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development 133:3787-3796.
    • (2006) Development , vol.133 , pp. 3787-3796
    • Lindsley, R.C.1    Gill, J.G.2    Kyba, M.3    Murphy, T.L.4    Murphy, K.M.5
  • 65
    • 58249095955 scopus 로고    scopus 로고
    • Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium
    • Nakanishi M, A Kurisaki, Y Hayashi, M Warashina, S Ishiura, M Kusuda-Furue and M Asashima. (2009). Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum-free medium. FASEB J 23:114-122.
    • (2009) FASEB J , vol.23 , pp. 114-122
    • Nakanishi, M.1    Kurisaki, A.2    Hayashi, Y.3    Warashina, M.4    Ishiura, S.5    Kusuda-Furue, M.6    Asashima, M.7
  • 66
    • 41149174852 scopus 로고    scopus 로고
    • Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
    • Cole MF, SE Johnstone, JJ Newman, MH Kagey and RA Young. (2008). Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev 22: 746-755.
    • (2008) Genes Dev , vol.22 , pp. 746-755
    • Cole, M.F.1    Johnstone, S.E.2    Newman, J.J.3    Kagey, M.H.4    Young, R.A.5
  • 67
    • 33749645068 scopus 로고    scopus 로고
    • Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell selfrenewal
    • Pereira L, F Yi and BJ Merrill. (2006). Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell selfrenewal. Mol Cell Biol 26:7479-7491.
    • (2006) Mol Cell Biol , vol.26 , pp. 7479-7491
    • Pereira, L.1    Yi, F.2    Merrill, B.J.3
  • 68
    • 54849408417 scopus 로고    scopus 로고
    • T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways
    • Tam WL, CY Lim, J Han, J Zhang, YS Ang, HH Ng, H Yang and B Lim. (2008). T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways. Stem Cells 26:2019-2031.
    • (2008) Stem Cells , vol.26 , pp. 2019-2031
    • Tam, W.L.1    Lim, C.Y.2    Han, J.3    Zhang, J.4    Ang, Y.S.5    Ng., H.H.6    Yang, H.7    Lim, B.8
  • 69
    • 0034716888 scopus 로고    scopus 로고
    • A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
    • Grosshans J and E Wieschaus. (2000). A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell 101:523-531.
    • (2000) Cell , vol.101 , pp. 523-531
    • Grosshans, J.1    Wieschaus, E.2
  • 70
    • 0034213302 scopus 로고    scopus 로고
    • Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation
    • Seher TC and M Leptin. (2000). Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation. Curr Biol 10:623-629.
    • (2000) Curr Biol , vol.10 , pp. 623-629
    • Seher, T.C.1    Leptin, M.2
  • 71
    • 38549161152 scopus 로고    scopus 로고
    • Cell fate determination during G1 phase progression
    • Blomen VA and J Boonstra. (2007). Cell fate determination during G1 phase progression. Cell Mol Life Sci 64:3084-3104.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 3084-3104
    • Blomen, V.A.1    Boonstra, J.2
  • 73
    • 0033152966 scopus 로고    scopus 로고
    • Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
    • Burdon T, C Stracey, I Chambers, J Nichols and A Smith. (1999). Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev Biol 210: 30-43.
    • (1999) Dev Biol , vol.210 , pp. 30-43
    • Burdon, T.1    Stracey I, C.2    Chambers, J.3    Nichols And, A.S.4
  • 74
    • 38349132624 scopus 로고    scopus 로고
    • Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation
    • Orford KW and DT Scadden. (2008). Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation. Nat Rev Genet 9:115-128.
    • (2008) Nat Rev Genet , vol.9 , pp. 115-128
    • Orford, K.W.1    Scadden, D.T.2
  • 75
    • 67649380739 scopus 로고    scopus 로고
    • Immunohistochemical expression of geminin in colorectal cancer: Implication of prognostic significance
    • Nishihara K, K Shomori, T Tamura, S Fujioka, T Ogawa and H Ito. (2009). Immunohistochemical expression of geminin in colorectal cancer: Implication of prognostic significance. Oncol Rep 21:1189-1195.
    • (2009) Oncol Rep , vol.21 , pp. 1189-1195
    • Nishihara, K.1    Shomori, K.2    Tamura, T.3    Fujioka, S.4    Ogawa, T.5    Ito, H.6
  • 76
    • 4344710758 scopus 로고    scopus 로고
    • Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines
    • Xouri G, Z Lygerou, H Nishitani, V Pachnis, P Nurse and S Taraviras. (2004). Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines. Eur J Biochem 271:3368-3378.
    • (2004) Eur J Biochem , vol.271 , pp. 3368-3378
    • Xouri, G.1    Lygerou, Z.2    Nishitani, H.3    Pachnis, V.4    Nurse, P.5    Taraviras, S.6
  • 77
    • 10044298303 scopus 로고    scopus 로고
    • Increased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumors
    • Montanari M, A Boninsegna, B Faraglia, C Coco, A Giordano, A Cittadini and A Sgambato. (2005). Increased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumors. J Cell Physiol 202:215-222.
    • (2005) J Cell Physiol , vol.202 , pp. 215-222
    • Montanari, M.1    Boninsegna, A.2    Faraglia, B.3    Coco, C.4    Giordano, A.5    Cittadini, A.6    Sgambato, A.7
  • 78
    • 79551471984 scopus 로고    scopus 로고
    • Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation
    • Aokage K, G Ishii, Y Ohtaki, Y Yamaguchi, T Hishida, J Yoshida, M Nishimura, K Nagai and A Ochiai. (2011). Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation. Int J Cancer 128:1585-1595.
    • (2011) Int J Cancer , vol.128 , pp. 1585-1595
    • Aokage, K.1    Ishii, G.2    Ohtaki, Y.3    Yamaguchi, Y.4    Hishida, T.5    Yoshida, J.6    Nishimura, M.7    Nagai, K.8    Ochiai, A.9


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