Expression of geminin as a marker of cell proliferation in normal tissues and malignancies

American Journal of Pathology

Volumn 161, Issue 1, 2002, Pages 267-273

  Wohlschlegel, J A ^b   Kutok, J L ^b   Weng, A P ^b   Dutta, A ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GEMININ; KI 67 ANTIGEN; PROTEIN P21; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; CANCER; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DNA REPLICATION; EPITHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE PROLIFERATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; XENOPUS;

EID: 0036313608     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64178-8     Document Type: Article

References (20)

1. Proliferation, cell cycle, and apoptosis in cancer
2. P27 in cell cycle control and cancer
3. Deregulation of the cell cycle in cancer
4. Cancer cell cycles
5. Initiation of DNA replication in eukaryotic cells
6. Regulation of chromosome replication
7. DNA replication: Building the perfect switch
8. Geminin, an inhibitor of DNA replication, is degraded during mitosis
9. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1
10. Repression of origin assembly in metaphase depends on inhibition of RLF- B/Cdt1 by geminin
11. Cell cycle. License withheld: Geminin blocks DNA replication
12. Expression of cell cycle-regulated proteins in prostate cancer
13. Cyclins as markers of tumor proliferation: Immunocytochemical studies in breast cancer
14. Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases
15. 1 and is destabilized after initiation of S-phase
16. Activity and nature of p21(WAF1) complexes during the cell cycle
17. Cyclin-binding motifs are essential for the function of p21CIP1
18. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
19. New functional activities for the p21 family of CDK inhibitors