P53-independent early and late apoptosis is mediated by ceramide after exposure of tumor cells to photon or carbon ion irradiation

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Alphonse, Gersende ^a,b,c   Maalouf, Mira ^a,b   Battiston Montagne, Priscillia ^a,b   Ardail, Dominique ^a,b,d   Beuve, Michaël ^a,b,e   Rousson, Robert ^d   Taucher Scholz, Gisela ^f   Fournier, Claudia ^f   Rodriguez Lafrasse, Claire ^a,b,c  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

^c CENTRE HOSPITALIER LYON SUD   (France)

^d HOSPICES CIVILS DE LYON   (France)

^e CENTRE DE CALCUL DE L INSTITUT NATIONAL DE PHYSIQUE NUCLEAIRE ET DE PHYSIQUE DES PARTICULES   (France)

^f GSI HELMHOLTZZENTRUM FÜR SCHWERIONENFORSCHUNG GMBH   (Germany)

Author keywords

Carbon ion irradiation; Ceramide; Early and late apoptosis; High and low LET irradiation; p53 independent apoptosis

Indexed keywords

CASPASE; CERAMIDE; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GLIOMA; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ION THERAPY; LIPOGENESIS; PHOTON THERAPY; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY;

APOPTOSIS; CARBON; CASPASES; CELL LINE, TUMOR; CERAMIDES; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; KINETICS; MITOCHONDRIA; PHOTONS; RADIATION, IONIZING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84876144534     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-151     Document Type: Article

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