Thermal adaptability of Kluyveromyces marxianus in recombinant protein production

Microbial Cell Factories

Volumn 12, Issue 1, 2013, Pages

  Raimondi, Stefano ^a   Zanni, Elena ^b   Amaretti, Alberto ^a   Palleschi, Claudio ^b   Uccelletti, Daniela ^b   Rossi, Maddalena ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA FRUCTOFURANOSIDASE; GLUCAN 1,4 ALPHA GLUCOSIDASE; HUMAN SERUM ALBUMIN; RECOMBINANT PROTEIN;

ARTICLE; ARXULA; ARXULA ADENINIVORANS; BIOMASS; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL STRAIN; FUNGUS GROWTH; HEAT ACCLIMATIZATION; KLUYVEROMYCES MARXIANUS; NONHUMAN; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; TEMPERATURE; WILD TYPE; YEAST;

BETA-FRUCTOFURANOSIDASE; BIOMASS; GLUCAN 1,4-ALPHA-GLUCOSIDASE; HUMANS; KLUYVEROMYCES; RECOMBINANT PROTEINS; SERUM ALBUMIN; SUPEROXIDE DISMUTASE; TEMPERATURE;

EUKARYOTA; KLUYVEROMYCES MARXIANUS;

EID: 84876128647     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-12-34     Document Type: Article

References (42)

1. Iborra F. High efficiency transformation of Kluyveromyces marxianus by a replicative plasmid. Curr Genet 1993, 24:181-183. 10.1007/BF00324685, 8358827.
2. Fonseca GG, Heinzle E, Wittmann C, Gombert AK. The yeast Kluyveromyces marxianus and its biotechnological potential. Appl Microbiol Biotechnol 2008, 79:339-354. 10.1007/s00253-008-1458-6, 18427804.
3. Diniz RH, Silveira WB, Fietto LG, Passos FM. The high fermentative metabolism of Kluyveromyces marxianus UFV-3 relies on the increased expression of key lactose metabolic enzymes. Antonie Van Leeuwenhoek 2012, 101:541-550. 10.1007/s10482-011-9668-9, 22068918.
4. Dos Santos VC, Bragança CR, Passos FJ, Passos FM. Kinetics of growth and ethanol formation from a mix of glucose/xylose substrate by Kluyveromyces marxianus UFV-3. Antonie Van Leeuwenhoek 2013, 103:153-161. 10.1007/s10482-012-9794-z, 22965752.
5. López-Alvarez A, Díaz-Pérez AL, Sosa-Aguirre C, Macías-Rodríguez L, Campos-García J. Ethanol yield and volatile compound content in fermentation of agave must by Kluyveromyces marxianus UMPe-1 comparing with Saccharomyces cerevisiae baker's yeast used in tequila production. J Biosci Bioeng 2012, 113(5):614-618. 10.1016/j.jbiosc.2011.12.015, 22280963.
6. Lee KS, Kim JS, Heo P, Yang TJ, Sung YJ, Cheon Y, Koo HM, Yu BJ, Seo JH, Jin YS, Park JC, Kweon DH. Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus. Appl Microbiol Biotechnol 2012, Epub ahead of print.
7. Jeong H, Lee DH, Kim SH, Kim HJ, Lee K, Song JY, Kim BK, Sung BH, Park JC, Sohn JH, Koo HM, Kim JF. Genome sequence of the thermotolerant yeast Kluyveromyces marxianus var. marxianus KCTC 17555. Eukaryot Cell 2012, 11(12):1584-1585. 10.1128/EC.00260-12, 23193140.
8. Rocha SN, Abrahão-Neto J, Cerdán ME, Gombert AK, González-Siso MI. Heterologous expression of a thermophilic esterase in Kluyveromyces yeasts. Appl Microbiol Biotechnol 2011, 89:375-385. 10.1007/s00253-010-2869-8, 20862582.
9. Rocha SN, Abrahão-Neto J, Cerdán ME, González-Siso MI, Gombert AK. Heterologous expression of glucose oxidase in the yeast Kluyveromyces marxianus. Microb Cell Fact 2010, 9:4. 10.1186/1475-2859-9-4, 2817671, 20092622.
10. Raimondi S, Uccelletti D, Amaretti A, Leonardi A, Palleschi C, Rossi M. Secretion of Kluyveromyces lactis Cu/Zn SOD: strategies for enhanced production. Appl Microbiol Biotechnol 2010, 86:871-878. 10.1007/s00253-009-2353-5, 20012282.
11. Foukis A, Stergiou PY, Theodorou LG, Papagianni M, Papamichael EM. Purification, kinetic characterization and properties of a novel thermo-tolerant extracellular protease from Kluyveromyces marxianus IFO 0288 with potential biotechnological interest. Bioresour Technol 2012, 123:214-220.
12. Rossi M, Buzzini P, Cordisco L, Amaretti A, Sala M, Raimondi S, Ponzoni C, Pagnoni UM, Matteuzzi D. Growth, lipid accumulation, and fatty acid composition in obligate psychrophilic, facultative psychrophilic, and mesophilic yeasts. FEMS Microbiol Ecol 2009, 69:363-372. 10.1111/j.1574-6941.2009.00727.x, 19624740.
13. García-Fruitós E, Vazquez E, Gonzalez-Montalbán N, Ferrer-Miralles N, Villaverde A. Analytical approaches for assessing aggregation of protein biopharmaceuticals. Curr Pharm Biotechnol 2011, 12:1530-1536. 10.2174/138920111798357339, 21542795.
14. Maldonado LMTP, Hernández VEB, Rivero EM, de la Rosa AP B, Flores JLF, Acevedo LGO, De León Rodríguez A. Optimization of culture conditions for a synthetic gene expression in Escherichia coli using response surface methodology: the case of human interferon beta. Biomol Eng 2007, 24:217-222. 10.1016/j.bioeng.2006.10.001, 17126075.
15. Noguère C, Larsson AM, Guyot JC, Bignon C. Fractional factorial approach combining 4 Escherichia coli strains, 3 culture media, 3 expression temperatures and 5 N-terminal fusion tags for screening the soluble expression of recombinant proteins. Protein Expr Purif 2012, 84:204-213. 10.1016/j.pep.2012.05.011, 22705765.
16. Baneyx F, Mujacic M. Recombinant protein folding and misfolding in Escherichia coli. Nat Biotechnol 2004, 22:1399-1408. 10.1038/nbt1029, 15529165.
17. Dragosits M, Stadlmann J, Albiol J, Baumann K, Maurer M, Gasser B, Sauer M, Altmann F, Ferrer P, Mattanovich D. The effect of temperature on the proteome of recombinant Pichia pastoris. J Proteome Res 2009, 8:1380-1392. 10.1021/pr8007623, 19216534.
18. Li Z, Xiong F, Lin Q, D'Anjou M, Daugulis AJ, Yang DS, Hew CL. Low-temperature increases the yield of biologically active herring antifreeze protein in Pichia pastoris. Protein Expr Purif 2001, 21:438-445. 10.1006/prep.2001.1395, 11281719.
19. Gasser B, Maurer M, Rautio J, Sauer M, Bhattacharyya A, Saloheimo M, Penttilä M, Mattanovich D. Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions. BMC Genomics 2007, 8:179. 10.1186/1471-2164-8-179, 1919374, 17578563.
20. Morlino GB, Tizzani L, Bianchi MM, Frontali L. Inducible amplification of gene copy number and heterologous proten production in the yeast Kluyveromyces lactis. Appl Environ Microbiol 1999, 65:4808-4813. 91648, 10543790.
21. Saliola M, Mazzoni C, Solimando N, Crisà A, Falcone C, Jung G. FleerR: Use of the KlADH4 promoter for ethanol-dependent production of recombinant Human Serum Albumin in Kluyveromyces lactis. Appl Environ Microbiol 1999, 65:53-60. 90982, 9872759.
22. Raimondi S, Uccelletti D, Matteuzzi D, Pagnoni UM, Rossi M, Palleschi C. Characterization of the superoxide dismutase SOD1 gene of Kluyveromyces marxianus L3 and improved production of SOD activity. Appl Microbiol Biotechnol 2008, 77:1269-1277. 10.1007/s00253-007-1270-8, 18040680.
23. Lane MM, Burke N, Karreman R, Wolfe KH, O'Byrne CP, Morrissey JP. Physiological and metabolic diversity in the yeast Kluyveromyces marxianus. Antonie Van Leeuwenhoek 2011, 100:507-519. 10.1007/s10482-011-9606-x, 21674230.
24. Fonseca GG, Gombert AK, Heinzle E, Wittmann C. Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source. FEMS Yeast Res 2007, 7:422-435. 10.1111/j.1567-1364.2006.00192.x, 17233766.
25. Masoud W, Jespersen L. Pectin degrading enzymes in yeasts involved in fermentation of Coffea arabica in East Africa. Int J Food Microbiol 2006, 110:291-296. 10.1016/j.ijfoodmicro.2006.04.030, 16784790.
26. Arrizon J, Morel S, Gschaedler A, Monsan P. Purification and substrate specificities of a fructanase from Kluyveromyces marxianus isolated from the fermentation process of Mezcal. Bioresour Technol 2011, 102:3298-3303. 10.1016/j.biortech.2010.10.071, 21067917.
27. Rouwenhorst RJ, Ritmeester WS, Scheffers WA, Van Dijken JP. Localization of inulinase and invertase in Kluyveromyces species. Appl Environ Microbiol 1990, 56:3329-3336. 184950, 2268150.
28. Dragosits M, Frascotti G, Bernard-Granger L, Vázquez F, Giuliani M, Baumann K, Rodríguez-Carmona E, Tokkanen J, Parrilli E, Wiebe MG, Kunert R, Maurer M, Gasser B, Sauer M, Branduardi P, Pakula T, Saloheimo M, Penttilä M, Ferrer P, Luisa Tutino M, Villaverde A, Porro D, Mattanovich D. Influence of growth temperature on the production of antibody Fab fragments in different microbes: a host comparative analysis. Biotechnol Prog 2011, 27:38-46. 10.1002/btpr.524, 21312353.
29. Zhang Y, Li T, Liu J. Low temperature and glucose enhanced T7 RNA polymerase-based plasmid stability for increasing expression of glucagons-like peptide-2 in Escherichia coli. Protein Expr Purif 2003, 29:132-139. 10.1016/S1046-5928(03)00002-0, 12729734.
30. Zhang Z, Moo-Young M, Chisti Y. Plasmid stability in recombinant Saccharomyces cerevisiae. Biotechnol Adv 1996, 14:401-435. 10.1016/S0734-9750(96)00033-X, 14540156.
31. Glick BR. Metabolic load and heterologous gene expression. Biotechnol Adv 1995, 13:247-261. 10.1016/0734-9750(95)00004-A, 14537822.
32. Neubauer P, Lin HY, Mathiszik B. Metabolic load of recombinant protein production: inhibition of cellular capacities for glucose uptake and respiration after induction of a heterologous gene in Escherichia coli. Biotechnol Bioeng 2003, 83:53-64. 10.1002/bit.10645, 12740933.
33. Mazzoni C, Santori F, Saliola M, Falcone C. Molecular analysis of UAS(E), a cis element containing stress response elements responsible for ethanol induction of the KlADH4 gene of Kluyveromyces lactis. Res Microbiol 2000, 151:19-28. 10.1016/S0923-2508(00)00131-5, 10724480.
34. Davidson JF, Whyte B, Bissinger PH, Schiestl RH. Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. PNAS 1996, 93:5116-5121. 10.1073/pnas.93.10.5116, 39416, 8643537.
35. Dellomonaco C, Amaretti A, Zanoni S, Pompei A, Matteuzzi D, Rossi M. Fermentative production of superoxide dismutase with Kluyveromyces marxianus. J Ind Microbiol Biotechnol 2007, 34:27-34.
36. Burkert JFM, Kalil SJ, Maugeri Filho F, Rodrigues MI. Parameters optimization for enzymatic assays using experimental design. Braz J ChemEng 2006, 23:163-170.
37. Miller GL. Use of dinitrosalisylic acid reagent for determination of reducing sugar. Anal Chem 1959, 31:426-428.
38. Laemmli UK. Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4. Nature 1970, 227:680-685. 10.1038/227680a0, 5432063.
39. Schmitt ME, Brown TA, Trumpower BL. A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res 1990, 18:3091-3092. 10.1093/nar/18.10.3091, 330876, 2190191.
40. McCord JM, Keele BB, Fridovich I. An enzyme-based theory of obligate anaerobiosis: the physiological function of superoxide dismutase. Proc Natl Acad Sci 1971, 68:1024-1027. 10.1073/pnas.68.5.1024, 389105, 4995818.
41. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Current protocols in molecular biology 1994, New York: Greene Publishing Associates and Wiley-Interscience.
42. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual 2001, New York, NY: Cold Spring Harbor Laboratory Press, 2.