-
1
-
-
62849128369
-
Renal cell carcinoma
-
Rini, B.I.; Campbell, S.C.; Escudier, B. Renal cell carcinoma. Lancet, 2009, 373, 1119-1132.
-
(2009)
Lancet
, vol.373
, pp. 1119-1132
-
-
Rini, B.I.1
Campbell, S.C.2
Escudier, B.3
-
2
-
-
34247385434
-
Evolving principles of surgical management and prognostic factors for outcome in renal cell carcinoma
-
DOI 10.1200/JCO.2006.08.1794
-
Lam, J.S.; Breda, A.; Belldegrun, A.S.; Figlin, R.A. Evolving principles of surgical management and prognostic factors for outcome in renal cell carcinoma. J. Clin. Oncol. 2006, 35, 5565-5575. (Pubitemid 46631337)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.35
, pp. 5565-5575
-
-
Lam, J.S.1
Breda, A.2
Belldegrun, A.S.3
Figlin, R.A.4
-
3
-
-
0027273479
-
Cytotoxic chemotherapy for advanced renal cell carcinoma
-
Pagoda, A.; Petrylak, D.; Thompson, S. Cytotoxic chemotherapy for advanced renal cell carcinoma. Urol. Clin. North. Amer. 1993, 20, 303-321. (Pubitemid 23154480)
-
(1993)
Urologic Clinics of North America
, vol.20
, Issue.2
, pp. 303-321
-
-
Yagoda, A.1
Petrylak, D.2
Thompson, S.3
-
4
-
-
34247248911
-
Role of cytokine therapy in 2006 and beyond for metastatic renal cell cancer
-
DOI 10.1200/JCO.2006.08.1638
-
Parton, M.; Gore, M.; Eisen, T. Role of cytokine therapy in 2006 and beyond for metastatic renal cell cancer. J. Clin. Oncol. 2006, 24, 5584-5592. (Pubitemid 46631339)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.35
, pp. 5584-5592
-
-
Parton, M.1
Gore, M.2
Eisen, T.3
-
5
-
-
73349107447
-
Update on novel agents in renal cell carcinoma
-
Tamaskar, I.; Pili. R. Update on novel agents in renal cell carcinoma. Expert. Rev. Anticancer Ther. 2009, 9(12), 1817-1827.
-
(2009)
Expert. Rev. Anticancer Ther
, vol.9
, Issue.12
, pp. 1817-1827
-
-
Tamaskar, I.1
Pili, R.2
-
6
-
-
0034693799
-
The protein tyrosine kinase family f the human genome
-
Robinson, D.R.; Wu, Y.; Lin, S. The protein tyrosine kinase family f the human genome. Oncogene, 2000, 19, 5548-5557.
-
(2000)
Oncogene
, vol.19
, pp. 5548-5557
-
-
Robinson, D.R.1
Wu, Y.2
Lin, S.3
-
7
-
-
77953536522
-
Kinase targets in renal-cell carcinomas: Reassessing the old and discovering the new
-
April 8 [e-pub ahead of print]
-
Furge, K.A.; MacKeigan, J.P.; The, B.T. Kinase targets in renal-cell carcinomas: reassessing the old and discovering the new. Lancet Oncol. 2010, April 8 [e-pub ahead of print].
-
(2010)
Lancet Oncol.
-
-
Furge, K.A.1
MacKeigan, J.P.2
The, B.T.3
-
8
-
-
0042342564
-
The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer
-
DOI 10.1056/NEJMp030061
-
George, D.J.; Kaelin Jr, W.G. The von Hippel Lindau protein, vascular endothelial growth factor, and kidney cancer. N. Engl. J. Med. 2003, 349, 419-421. (Pubitemid 36910018)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 419-421
-
-
George, D.J.1
Kaelin Jr., W.G.2
-
9
-
-
77951258203
-
Bevacizumab as a treatment option in advanced renal cell carcinoma: An analysis and interpretation of clinical trial data
-
McDermott, D.F.; George, D.J. Bevacizumab as a treatment option in advanced renal cell carcinoma: an analysis and interpretation of clinical trial data. Cancer Treat. Rev. 2010, 36, 216-223.
-
(2010)
Cancer Treat. Rev.
, vol.36
, pp. 216-223
-
-
McDermott, D.F.1
George, D.J.2
-
10
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer, R.J.; Hutson, T.E.; Tomczak, P.; Michaelson, M.D.; Bukowski, R.M.; Rixe, O.; Oudard, S.; Negrier, S.; Szczylik, C.; Kim, S.T.; Chen, I.; Bycott, P.W.; Baum, C.M.; Figlin, R.A. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N. Engl. J. Med. 2007,356, 115-124. (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
11
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier, B.; Eisen, T.; Stadler, W.M.; Szczylik, C.; Oudard, S.; Siebels, M.; Negrier, S.; Chevreau, C.; Solska, E.; Desai, A.A.; Rolland, F.; Demkow, T.; Hutson, T.E.; Gore, M.; Freeman, S.; Schwartz, B.; Shan, M.; Simantov, R.; Bukowski, R.M. Sorafenib in advanced clear-cell renal cell carcinoma. N. Engl. J. Med. 2007, 356, 125-134. (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
12
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier, B.; Pluzanska, A.; Koralewski, P.; Ravaud, A.; Bracarda, S.; Szczylik, C.; Chevreau, C.; Filipek, M.; Melichar, B.; Bajetta, E.; Gorbunova, V.; Bay, J.O.; Bodrogi, I.; Jagiello-Gruszfeld, A.; Moore, N. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma : a randomised, double-blind phase III trial. Lancet, 2007, 370, 2103-2111. (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
13
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
DOI 10.1056/NEJMoa021491
-
Yang, J.C.; Howort, L.; Sherry, R.; et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N. Engl. J. Med. 2003,349, 427-434. (Pubitemid 36910021)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
14
-
-
14144252047
-
Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.05.179
-
Mekhail, T.M.; Abou-Jawde, R.M.; Bou-Merhi, G.; et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastitic renal cell carcinoma. J. Clin. Oncol. 2005, 23, 832-841. (Pubitemid 46224183)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.4
, pp. 832-841
-
-
Mekhail, T.M.1
Abou-Jawde, R.M.2
BouMerhi, G.3
Malhi, S.4
Wood, L.5
Elson, P.6
Bukowski, R.7
-
15
-
-
65449145132
-
Recent advances in molecular targeted therapy for metastatic renal cell carcinoma
-
Mizutani, Y. Recent advances in molecular targeted therapy for metastatic renal cell carcinoma. Int. J. Urol. 2009, 16, 444-448.
-
(2009)
Int. J. Urol
, vol.16
, pp. 444-448
-
-
Mizutani, Y.1
-
16
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
Escudier, B.; Bellmunt, J.; Negrier, S.; Bajetta, E.; Melichar, B.; Bracarda, S.; Ravaud, A.; Golding, S.; Jethwa, S.; Sneller, V. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J. Clin. Oncol. 2010, 28, 2137-2143.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2137-2143
-
-
Escudier, B.1
Bellmunt, J.2
Negrier, S.3
Bajetta, E.4
Melichar, B.5
Bracarda, S.6
Ravaud, A.7
Golding, S.8
Jethwa, S.9
Sneller, V.10
-
17
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
Rini, B.I.; Halabi, S.; Rosenberg, J.E.; Stadler, W.M.; Vaena, D.A.; Archer, L.; Atkins, J.N.; Picus, J.; Czaykowski, P.; Dutcher,J.; Small, E.J. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J. Clin. Oncol., 2010, 28, 2137-2143.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
Stadler, W.M.4
Vaena, D.A.5
Archer, L.6
Atkins, J.N.7
Picus, J.8
Czaykowski, P.9
Dutcherj10
Small, E.J.11
-
18
-
-
0036401042
-
Design and discovery of small molecules targeting Raf-1 kinase
-
DOI 10.2174/1381612023393125
-
Lowinger, T.B.; Riedl, B.; Dumas, J.; Smith, R.A. Design and discovery of small molecules targeting raf-1 kinase. Curr. Pharm. Des. 2002, 8, 2269-2278. (Pubitemid 35189900)
-
(2002)
Current Pharmaceutical Design
, vol.8
, Issue.25
, pp. 2269-2278
-
-
Lowinger, T.B.1
Riedl, B.2
Dumas, J.3
Smith, R.A.4
-
19
-
-
0036401105
-
BAY 43-9006: Preclinical data
-
DOI 10.2174/1381612023393026
-
Wilhelm, S.; Chien, D.S. BAY 43-9006: preclinical data. Curr. Pharm. Des. 2002, 8, 2255-2257. (Pubitemid 35189898)
-
(2002)
Current Pharmaceutical Design
, vol.8
, Issue.25
, pp. 2255-2257
-
-
Wilhelm, S.1
Chien, D.-S.2
-
20
-
-
34447120142
-
Sorafenib and sunitinib in renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-2844
-
Stein, M.N.; Flaherty, K.T. Sorafenib and sunitinib in renal cell carcinoma. Clin. Cancer Res. 2007, 13, 3765-3770. (Pubitemid 47037579)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.13
, pp. 3765-3770
-
-
Stein, M.N.1
Flaherty, K.T.2
-
21
-
-
62449186539
-
Randomized phase II trial of first-line treatment with sorafenib versus interferon alfa-2a in patients with metastatic renal cell carcinoma
-
Escudier, B.; Szczylik, C.; Hutson, T.E.; Demkow, T.; Staehler, M.; Rolland, F.; Negrier, S.; Laferriere, N.; Scheuring, U.J.; Cella, D.; Shah, S.; Bukowski, R.M. Randomized phase II trial of first-line treatment with sorafenib versus interferon alfa-2a in patients with metastatic renal cell carcinoma. J. Clin. Oncol. 2009, 27, 1280-1289.
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 1280-1289
-
-
Escudier, B.1
Szczylik, C.2
Hutson, T.E.3
Demkow, T.4
Staehler, M.5
Rolland, F.6
Negrier, S.7
Laferriere, N.8
Scheuring, U.J.9
Cella, D.10
Shah, S.11
Bukowski, R.M.12
-
22
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel, D.B.; Laird, A.D.; Xin, X.; Louie, S.G.; Christensen, J.G.; Li, G.; Schreck, R.E.; Abrams, T.J.; Ngai, T.J.; Lee, L.B.; Murray, L.J.; Carver, J.; Chan, E.; Moss, K.G.; Haznedar, J.O.; Sukbuntherng, J.; Blake, R.A.; Sun, L.; Tang, C.; Miller, T.; Shirazian, S.; McMahon, G.; Cherrington, J.M. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting VEGF and PDGF receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin. Cancer Res. 2003, 9, 327-337. (Pubitemid 36109749)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1 I
, pp. 327-337
-
-
Mendel, D.B.1
Douglas Laird, A.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
23
-
-
36049006487
-
New challenges in kidney cancer therapy: Sunitinib
-
Izzedine, H.; Billemont, B.; Thibault, F.; Rixe, O. New challenges in kidney cancer therapy: sunitinib. Annals of Oncol. 2007, 18, ix83-6.
-
(2007)
Annals of Oncol
, vol.18
-
-
Izzedine, H.1
Billemont, B.2
Thibault, F.3
Rixe, O.4
-
24
-
-
33644847440
-
Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
-
DOI 10.1200/JCO.2005.02.2194
-
Faivre, S.; Delbaldo, C.; Vera, K.; Robert, C.; Lozahic, S.; Lassau, N.; Bello, C.; Deprimo, S.; Brega, N.; Massimini, G.; Armand, J.P.; Scigalla, P.; Raymond, E. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patirnts with cancer. J. Clin. Oncol., 2006, 24, 25-35. (Pubitemid 46630490)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 25-35
-
-
Faivre, S.1
Delbaldo, C.2
Vera, K.3
Robert, C.4
Lozahic, S.5
Lassau, N.6
Bello, C.7
Deprimo, S.8
Brega, N.9
Massimini, G.10
Armand, J.-P.11
Scigalla, P.12
Raymond, E.13
-
25
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
DOI 10.1001/jama.295.21.2516
-
Motzer, R.J.; Rini, B.I.; Bukowski, R.M.; Curti, B.D.; George, D.J.; Hudes, G.R.; redman, B.G.; Margolin, K.A.; Merchan, J.R.; Wilding, G.; Ginsberg, M.S.; Bacik, J.; Kim, S.T.; Baum, C.M.; Michaelson, M.D. Sunitinib in patients with metastatic renal cell carcinoma. JAMA, 2006, 295, 2516-2524. (Pubitemid 43854967)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.21
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
Curti, B.D.4
George, D.J.5
Hudes, G.R.6
Redman, B.G.7
Margolin, K.A.8
Merchan, J.R.9
Wilding, G.10
Ginsberg, M.S.11
Bacik, J.12
Kim, S.T.13
Baum, C.M.14
Michaelson, M.D.15
-
26
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.02.2574
-
Motzer, R.J.; Michaelson, M.D.; Redman, B.G.; Hudes, G.R.; Wilding, G.; Figlin, R.A.; Ginsberg, M.S.; Kim, S.T.; Baum, C.M.; DePrimo, S.E.; Li, J.Z.; Bello, C.L.; Theuer, C.P.; George, D.J.; Rini, B.I. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet derived growth factor receptor, in patients with metastatic renal cell carcinoma. J. Clin. Oncol., 2006, 24, 16-24. (Pubitemid 46630489)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
Hudes, G.R.4
Wilding, G.5
Figlin, R.A.6
Ginsberg, M.S.7
Kim, S.T.8
Baum, C.M.9
DePrimo, S.E.10
Li, J.Z.11
Bello, C.L.12
Theuer, C.P.13
George, D.J.14
Rini, B.I.15
-
27
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer, R.J.; Hutson, T.E.; Tomczak, P.; Michaelson, M.D.; Bukowski, R.M.; Rixe, O.; Oudard, S.; Negrier, S.; Szczylik, C.; Kim, S.T.; Chen, I.; Bycott, P.W.; Baum, P.W.; Figlin, R.A. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N. Engl. J. Med., 2007, 356, 115-124. (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
28
-
-
48649094719
-
Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment ofmetastatic renal cell carcinoma (mRCC)
-
May 20 suppl; abstr 5024)
-
Figlin, R.A.; Hutson, T.E.; Tomczak, P.; Michaelson, R.M.; Bukowski, R.M.; Nègrier, S.; Huang, X.; Kim, S.T.; Chen, I.; Motzer, R.J. Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment ofmetastatic renal cell carcinoma (mRCC). J. Clin. Oncol., 2008, 26, May 20 suppl; abstr 5024).
-
(2008)
J. Clin. Oncol
, vol.26
-
-
Figlin, R.A.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, R.M.4
Bukowski, R.M.5
Nègrier, S.6
Huang, X.7
Kim, S.T.8
Chen, I.9
Motzer, R.J.10
-
29
-
-
67651201656
-
Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: An expanded-access trial
-
Gore, M.E.; Szczylik, C.; Porta, C.; Bracarda, S.; Bjarnason, G.A.; Oudard, S.; Hariharan, S.; Lee, S.H.; Haanen, J.; Castellano, D.; Vrdoljak, E.; Schoffski, P.; Mainwaring, P.; Nieto, A.; Yuan, J.; Bukowski, R. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Lancet Oncol., 2009, 10, 757-763.
-
(2009)
Lancet Oncol
, vol.10
, pp. 757-763
-
-
Gore, M.E.1
Szczylik, C.2
Porta, C.3
Bracarda, S.4
Bjarnason, G.A.5
Oudard, S.6
Hariharan, S.7
Lee, S.H.8
Haanen, J.9
Castellano, D.10
Vrdoljak, E.11
Schoffski, P.12
Mainwaring, P.13
Nieto, A.14
Yuan, J.15
Bukowski, R.16
-
30
-
-
35549008792
-
Sequential use of sorafenib and sunitinib: Retrospective analysis in 90 patients
-
Sablin, M.P.; Bouaita, L.; Balleyguier, C.; et al. Sequential use of sorafenib and sunitinib: retrospective analysis in 90 patients. J. Clin. Oncol., 2007, 25, S244.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Sablin, M.P.1
Bouaita, L.2
Balleyguier, C.3
-
31
-
-
36549059204
-
Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
-
Dham, A.; Dudek, A.Z. Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. J. Clin. Oncol., 2007, 25, S261.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Dham, A.1
Dudek, A.Z.2
-
32
-
-
35448934762
-
Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study
-
DOI 10.1016/S1470-2045(07)70285-1, PII S1470204507702851
-
Rixe, O.; Bukowski, R.M.; Michaelson, M.D.; Wilding, G.; Hudes, G.R.; Bolte, O.; Motzer, R.J.; Bycott, P.; Liau, K.F.; Freddo, J.; Trask, P.C.; Kim, S.; Rini, B.I. Axitinib treatment in patients with cytokine-refractory metastatic renal cell cancer: a phase II study. Lancet Oncol., 2007, 8, 975-984. (Pubitemid 47629888)
-
(2007)
Lancet Oncology
, vol.8
, Issue.11
, pp. 975-984
-
-
Rixe, O.1
Bukowski, R.M.2
Michaelson, M.D.3
Wilding, G.4
Hudes, G.R.5
Bolte, O.6
Motzer, R.J.7
Bycott, P.8
Liau, K.F.9
Freddo, J.10
Trask, P.C.11
Kim, S.12
Rini, B.I.13
-
33
-
-
35549007093
-
Axitinib (AG-013736; AG) in patients with metastatic renal cell cancer (RCC) refractory to sorafenib
-
Rini, B.I.; Widing, G.T.; Hudes, W.M.; et al. Axitinib (AG-013736; AG) in patients with metastatic renal cell cancer (RCC) refractory to sorafenib. J. Clin. Oncol., 2007, 25, S242.
-
(2007)
J. Clin. Oncol
, vol.25
-
-
Rini, B.I.1
Widing, G.T.2
Hudes, W.M.3
-
34
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg, C.N.; Davis, I.D.; Mardiak, J.; Szczylik, C.; Lee, E.; Wagstaff, J.; Barrios, C.H.; Salman, P.; Gladkov, O.A.; Kavina, A.; Zarbà, J.J.; Chen, M.; McCann, L.; Pandite, L.; Roychowdhury, D.F.; Hawkins, R.E. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J. Clin. Oncol., 2010, 28, 1061-1068.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
Szczylik, C.4
Lee, E.5
Wagstaff, J.6
Barrios, C.H.7
Salman, P.8
Gladkov, O.A.9
Kavina, A.10
Zarbà, J.J.11
Chen, M.12
McCann, L.13
Pandite, L.14
Roychowdhury, D.F.15
Hawkins, R.E.16
-
35
-
-
77952928989
-
Pazopanib: An oral multitargeted tyrosine kinase inhibitor for use in renal cell carcinoma
-
LaPlant, K.D.; Louzon, P.D. Pazopanib: an oral multitargeted tyrosine kinase inhibitor for use in renal cell carcinoma. Ann. Pharmacother., 2010, 44, 1054-1060.
-
(2010)
Ann. Pharmacother.
, vol.44
, pp. 1054-1060
-
-
Laplant, K.D.1
Louzon, P.D.2
-
36
-
-
36048984061
-
Temsirolimus in the treatment of advanced renal cell carcinoma
-
Gore, M.E. Temsirolimus in the treatment of advanced renal cell carcinoma. Ann. Oncol., 2007, 18 (Suppl. 9), ix87-88.
-
(2007)
Ann. Oncol
, vol.18
, Issue.SUPPL. 9
-
-
Gore, M.E.1
-
37
-
-
65949091346
-
Targeting mTOR in renal cell carcinoma
-
Hudes, G.R. Targeting mTOR in renal cell carcinoma. Cancer, 2009, 115, 2313-2320.
-
(2009)
Cancer
, vol.115
, pp. 2313-2320
-
-
Hudes, G.R.1
-
38
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes, G.; Carducci, M.; Tomczak, P.; Dutcher, J.; Figlin, R.; Kapoor, A.; Staroslawska, E.; Sosman, J.; McDermott, D.; Bodrogi, I.; Kovacevic, Z.; Lesovoy, V.; Schmidt-Wolf, I.G.; Barbarash, O.; Gokmen, E.; O'Toole, T.; Lustgarten, S.; Moore, L.; Motzer, R.J. Temsirolimus, interferon alpha, or both for advanced renal-cell carcinoma. N. Engl. J. Med., 2007, 356, 2271-2281. (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
39
-
-
66649133114
-
A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer
-
Amato, R.J.; Jac, J.; Giessinger, S.; Saxena, S.; Willis, J.P. A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer. Cancer, 2009, 115, 2438-2446.
-
(2009)
Cancer
, vol.115
, pp. 2438-2446
-
-
Amato, R.J.1
Jac, J.2
Giessinger, S.3
Saxena, S.4
Willis, J.P.5
-
40
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma : a double-blind, randomised, placebocontrolled phase III trial
-
Motzer, R.J.; Escudier, B.; Oudard, S.; Hutson, T.E.; Porta, C.; Bracarda, S.; Grunwald, V.; Thompson, J.A.; Figlin, R.A.; Hollaender, N.; Urbanowitz, G.; Berg, W.J.; Kay, A.; Lebwohl, D.; Ravaud, A. Efficacy of everolimus in advanced renal cell carcinoma : a double-blind, randomised, placebocontrolled phase III trial. Lancet, 2008, 372, 449-456.
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
Grunwald, V.7
Thompson, J.A.8
Figlin, R.A.9
Hollaender, N.10
Urbanowitz, G.11
Berg, W.J.12
Kay, A.13
Lebwohl, D.14
Ravaud, A.15
-
41
-
-
77956227464
-
Phase III trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
-
Jun 14 [Epub ahead of print]
-
Motzer, R.J.; Escudier, B.; Oudard, S.; Hutson, T.E.; Porta, C.; Bracarda, S.; Grunwald, V.; Thompson, J.A.; Figlin, R.A.; Hollaender, N.; Kay, A.; Ravaud, A. Phase III trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors. Cancer, 2010, Jun 14 [Epub ahead of print].
-
(2010)
Cancer
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
Grunwald, V.7
Thompson, J.A.8
Figlin, R.A.9
Hollaender, N.10
Kay, A.11
Ravaud, A.12
-
42
-
-
79955686423
-
Sequential use of targeted agents in the treatment of renal cell carcinoma
-
Aug 11. [Epub ahead of print]
-
Hutson, T.E.; Bukowski, R.M.; Cowey, C.L.; Figlin, R.; Escudier, B.; Sternberg, C.N. Sequential use of targeted agents in the treatment of renal cell carcinoma. Crit. Rev. Oncol. Hematol., 2010, Aug 11. [Epub ahead of print].
-
(2010)
Crit. Rev. Oncol. Hematol.
-
-
Hutson, T.E.1
Bukowski, R.M.2
Cowey, C.L.3
Figlin, R.4
Escudier, B.5
Sternberg, C.N.6
-
43
-
-
65949118243
-
Combination targeted therapy in advanced renal cell carcinoma
-
Sosman, J.; Puzanov, I. Combination targeted therapy in advanced renal cell carcinoma. Cancer, 2009,115 (10 Suppl) , 2368-2375.
-
(2009)
Cancer
, vol.115
, Issue.10 SUPPL.
, pp. 2368-2375
-
-
Sosman, J.1
Puzanov, I.2
-
44
-
-
61449150659
-
Cytoreductive nephrectomy in metastatic clear-cell renal cell carcinoma: Perspectives in the tyrosine kinase inhibitor era
-
Biswas, S.; Kelly, J.; Eisen, T. Cytoreductive nephrectomy in metastatic clear-cell renal cell carcinoma: perspectives in the tyrosine kinase inhibitor era. The Oncologist, 2009, 14, 52-59.
-
(2009)
The Oncologist
, vol.14
, pp. 52-59
-
-
Biswas, S.1
Kelly, J.2
Eisen, T.3
|