메뉴 건너뛰기




Volumn 125, Issue 2, 2013, Pages 273-280

High-mobility group box 1 from reactive astrocytes enhances the accumulation of endothelial progenitor cells in damaged white matter

Author keywords

endothelial progenitor cells (EPCs); high mobility group box 1 (HMGB1); neurovascular unit; reactive astrocytes; white matter injury; white matter remodeling

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CD34 ANTIGEN; FIBROBLAST GROWTH FACTOR 2; GLIAL FIBRILLARY ACIDIC PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; LYSOPHOSPHATIDYLCHOLINE; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; VASCULOTROPIN RECEPTOR 2;

EID: 84876108387     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12120     Document Type: Article
Times cited : (53)

References (58)
  • 1
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • Andersson U., Wang H., Palmblad K., et al,. (2000) High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J. Exp. Med. 192, 565-570.
    • (2000) J. Exp. Med. , vol.192 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3
  • 2
    • 65549151388 scopus 로고    scopus 로고
    • An oligovascular niche: Cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells
    • Arai K., and, Lo E., (2009a) An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells. J. Neurosci. 29, 4351-4356.
    • (2009) J. Neurosci. , vol.29 , pp. 4351-4356
    • Arai, K.1    Lo, E.2
  • 3
    • 70349954953 scopus 로고    scopus 로고
    • Oligovascular signaling in white matter stroke
    • Arai K., and, Lo E., (2009b) Oligovascular signaling in white matter stroke. Biol. Pharm. Bull. 32, 1639-1683.
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 1639-1683
    • Arai, K.1    Lo, E.2
  • 4
    • 33646337394 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of neural repair after stroke: Making waves
    • Carmichael S. T., (2006) Cellular and molecular mechanisms of neural repair after stroke: making waves. Ann. Neurol. 59, 735-742.
    • (2006) Ann. Neurol. , vol.59 , pp. 735-742
    • Carmichael, S.T.1
  • 5
    • 84865822723 scopus 로고    scopus 로고
    • Hypertension induces brain beta-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature
    • Carnevale D., Mascio G., D'Andrea I., et al,. (2012) Hypertension induces brain beta-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature. Hypertension 60, 188-197.
    • (2012) Hypertension , vol.60 , pp. 188-197
    • Carnevale, D.1    Mascio, G.2    D'Andrea, I.3
  • 6
    • 34247545017 scopus 로고    scopus 로고
    • Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke
    • Caso J. R., Pradillo J. M., Hurtado O., Lorenzo P., Moro M. A., and, Lizasoain I., (2007) Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 115, 1599-1608.
    • (2007) Circulation , vol.115 , pp. 1599-1608
    • Caso, J.R.1    Pradillo, J.M.2    Hurtado, O.3    Lorenzo, P.4    Moro, M.A.5    Lizasoain, I.6
  • 8
    • 77951190309 scopus 로고    scopus 로고
    • Extracellular high mobility group box-1 (HMGB1) inhibits enterocyte migration via activation of Toll-like receptor-4 and increased cell-matrix adhesiveness
    • Dai S., Sodhi C., Cetin S., et al,. (2010) Extracellular high mobility group box-1 (HMGB1) inhibits enterocyte migration via activation of Toll-like receptor-4 and increased cell-matrix adhesiveness. J. Biol. Chem. 285, 4995-5002.
    • (2010) J. Biol. Chem. , vol.285 , pp. 4995-5002
    • Dai, S.1    Sodhi, C.2    Cetin, S.3
  • 9
    • 84859723641 scopus 로고    scopus 로고
    • A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
    • Deane R., Singh I., Sagare A. P., et al,. (2012) A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. J. Clin. Invest. 122, 1377-1392.
    • (2012) J. Clin. Invest. , vol.122 , pp. 1377-1392
    • Deane, R.1    Singh, I.2    Sagare, A.P.3
  • 10
    • 77951758771 scopus 로고    scopus 로고
    • Endothelial progenitor cell transplantation improves long-term stroke outcome in mice
    • Fan Y., Shen F., Frenzel T., et al,. (2010) Endothelial progenitor cell transplantation improves long-term stroke outcome in mice. Ann. Neurol. 67, 488-497.
    • (2010) Ann. Neurol. , vol.67 , pp. 488-497
    • Fan, Y.1    Shen, F.2    Frenzel, T.3
  • 11
    • 34848917621 scopus 로고    scopus 로고
    • High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo
    • Faraco G., Fossati S., Bianchi M. E., Patrone M., Pedrazzi M., Sparatore B., Moroni F., and, Chiarugi A., (2007) High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo. J. Neurochem. 103, 590-603.
    • (2007) J. Neurochem. , vol.103 , pp. 590-603
    • Faraco, G.1    Fossati, S.2    Bianchi, M.E.3    Patrone, M.4    Pedrazzi, M.5    Sparatore, B.6    Moroni, F.7    Chiarugi, A.8
  • 12
    • 20444422592 scopus 로고    scopus 로고
    • Extent of white matter lesions is related to acute subcortical infarcts and predicts further stroke risk in patients with first ever ischaemic stroke
    • Fu J. H., Lu C. Z., Hong Z., Dong Q., Luo Y., and, Wong K. S., (2005) Extent of white matter lesions is related to acute subcortical infarcts and predicts further stroke risk in patients with first ever ischaemic stroke. J. Neurol. Neurosurg. Psychiatry 76, 793-796.
    • (2005) J. Neurol. Neurosurg. Psychiatry , vol.76 , pp. 793-796
    • Fu, J.H.1    Lu, C.Z.2    Hong, Z.3    Dong, Q.4    Luo, Y.5    Wong, K.S.6
  • 13
    • 33745628553 scopus 로고    scopus 로고
    • Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia
    • Goldstein R. S., Gallowitsch-Puerta M., Yang L., et al,. (2006) Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia. Shock 25, 571-574.
    • (2006) Shock , vol.25 , pp. 571-574
    • Goldstein, R.S.1    Gallowitsch-Puerta, M.2    Yang, L.3
  • 14
    • 22944483792 scopus 로고    scopus 로고
    • The blood-brain barrier/neurovascular unit in health and disease
    • Hawkins B. T., and, Davis T. P., (2005) The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57, 173-185.
    • (2005) Pharmacol. Rev. , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 15
    • 84860794215 scopus 로고    scopus 로고
    • Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery
    • Hayakawa K., Pham L. D., Katusic Z. S., Arai K., and, Lo E. H., (2012a) Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery. Proc. Natl Acad. Sci. USA 109, 7505-7510.
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 7505-7510
    • Hayakawa, K.1    Pham, L.D.2    Katusic, Z.S.3    Arai, K.4    Lo, E.H.5
  • 16
    • 84862830743 scopus 로고    scopus 로고
    • Cerebral endothelial derived vascular endothelial growth factor promotes the migration but not the proliferation of oligodendrocyte precursor cells in vitro
    • Hayakawa K., Seo J., Pham L.-D., Miyamoto N., Som A., Guo S., Kim K.-W., Lo E., and, Arai K., (2012b) Cerebral endothelial derived vascular endothelial growth factor promotes the migration but not the proliferation of oligodendrocyte precursor cells in vitro. Neurosci. Lett. 513, 42-48.
    • (2012) Neurosci. Lett. , vol.513 , pp. 42-48
    • Hayakawa, K.1    Seo, J.2    Pham, L.-D.3    Miyamoto, N.4    Som, A.5    Guo, S.6    Kim, K.-W.7    Lo, E.8    Arai, K.9
  • 17
    • 35448993875 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion
    • Hua F., Ma J., Ha T., et al,. (2007) Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion. J. Neuroimmunol. 190, 101-111.
    • (2007) J. Neuroimmunol. , vol.190 , pp. 101-111
    • Hua, F.1    Ma, J.2    Ha, T.3
  • 18
    • 0034704068 scopus 로고    scopus 로고
    • Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation
    • Huttunen H. J., Kuja-Panula J., Sorci G., Agneletti A. L., Donato R., and, Rauvala H., (2000) Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. J. Biol. Chem. 275, 40096-40105.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40096-40105
    • Huttunen, H.J.1    Kuja-Panula, J.2    Sorci, G.3    Agneletti, A.L.4    Donato, R.5    Rauvala, H.6
  • 19
    • 0037064124 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation
    • Huttunen H. J., Kuja-Panula J., and, Rauvala H., (2002) Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation. J. Biol. Chem. 277, 38635-38646.
    • (2002) J. Biol. Chem. , vol.277 , pp. 38635-38646
    • Huttunen, H.J.1    Kuja-Panula, J.2    Rauvala, H.3
  • 20
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer's disease
    • Iadecola C., (2004) Neurovascular regulation in the normal brain and in Alzheimer's disease. Nat. Rev. Neurosci. 5, 347-360.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 347-360
    • Iadecola, C.1
  • 22
    • 0038744340 scopus 로고    scopus 로고
    • Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria
    • Laflamme N., Echchannaoui H., Landmann R., and, Rivest S., (2003) Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria. Eur. J. Immunol. 33, 1127-1138.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1127-1138
    • Laflamme, N.1    Echchannaoui, H.2    Landmann, R.3    Rivest, S.4
  • 23
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo E. H., Dalkara T., and, Moskowitz M. A., (2003) Mechanisms, challenges and opportunities in stroke. Nat. Rev. Neurosci. 4, 399-415.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 24
    • 0842289222 scopus 로고    scopus 로고
    • TPA and proteolysis in the neurovascular unit
    • Lo E. H., Broderick J. P., and, Moskowitz M. A., (2004) tPA and proteolysis in the neurovascular unit. Stroke 35, 354-356.
    • (2004) Stroke , vol.35 , pp. 354-356
    • Lo, E.H.1    Broderick, J.P.2    Moskowitz, M.A.3
  • 25
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze M. T., and, Tracey K. J., (2005) High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5, 331-342.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 26
    • 85028103629 scopus 로고    scopus 로고
    • Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice
    • Ma Q., Manaenko A., Khatibi N. H., Chen W., Zhang J. H., and, Tang J., (2010) Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice. J. Cereb. Blood Flow Metab. 31, 881-893.
    • (2010) J. Cereb. Blood Flow Metab. , vol.31 , pp. 881-893
    • Ma, Q.1    Manaenko, A.2    Khatibi, N.H.3    Chen, W.4    Zhang, J.H.5    Tang, J.6
  • 27
    • 79551657860 scopus 로고    scopus 로고
    • Critical questions for preclinical trials on safety and efficacy of vascular endothelial growth factor-based therapeutic angiogenesis for ischemic stroke
    • Manoonkitiwongsa P. S., (2011) Critical questions for preclinical trials on safety and efficacy of vascular endothelial growth factor-based therapeutic angiogenesis for ischemic stroke. CNS Neurol. Disord. Drug Targets 10, 215-234.
    • (2011) CNS Neurol. Disord. Drug Targets , vol.10 , pp. 215-234
    • Manoonkitiwongsa, P.S.1
  • 29
    • 34247468864 scopus 로고    scopus 로고
    • Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis
    • Mishra B. B., Mishra P. K., and, Teale J. M., (2006) Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis. J. Neuroimmunol. 181, 46-56.
    • (2006) J. Neuroimmunol. , vol.181 , pp. 46-56
    • Mishra, B.B.1    Mishra, P.K.2    Teale, J.M.3
  • 30
    • 0028858281 scopus 로고
    • Neurotrophic factors in central nervous system trauma
    • Mocchetti I., and, Wrathall J. R., (1995) Neurotrophic factors in central nervous system trauma. J. Neurotrauma 12, 853-870.
    • (1995) J. Neurotrauma , vol.12 , pp. 853-870
    • Mocchetti, I.1    Wrathall, J.R.2
  • 31
    • 77955487488 scopus 로고    scopus 로고
    • The science of stroke: Mechanisms in search of treatments
    • Moskowitz M. A., Lo E. H., and, Iadecola C., (2010) The science of stroke: mechanisms in search of treatments. Neuron 67, 181-198.
    • (2010) Neuron , vol.67 , pp. 181-198
    • Moskowitz, M.A.1    Lo, E.H.2    Iadecola, C.3
  • 35
    • 59349116941 scopus 로고    scopus 로고
    • Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression
    • Offner H., Vandenbark A. A., and, Hurn P. D., (2009) Effect of experimental stroke on peripheral immunity: CNS ischemia induces profound immunosuppression. Neuroscience 158, 1098-1111.
    • (2009) Neuroscience , vol.158 , pp. 1098-1111
    • Offner, H.1    Vandenbark, A.A.2    Hurn, P.D.3
  • 36
    • 0037376222 scopus 로고    scopus 로고
    • Activation of gene expression in human neutrophils by high mobility group box 1 protein
    • Park J. S., Arcaroli J., Yum H. K., et al,. (2003) Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am. J. Physiol. Cell Physiol. 284, C870-C879.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.284
    • Park, J.S.1    Arcaroli, J.2    Yum, H.K.3
  • 37
    • 0342894664 scopus 로고    scopus 로고
    • Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation
    • Passalacqua M., Patrone M., Picotti G. B., Del Rio M., Sparatore B., Melloni E., and, Pontremoli S., (1998) Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation. Neuroscience 82, 1021-1028.
    • (1998) Neuroscience , vol.82 , pp. 1021-1028
    • Passalacqua, M.1    Patrone, M.2    Picotti, G.B.3    Del Rio, M.4    Sparatore, B.5    Melloni, E.6    Pontremoli, S.7
  • 38
    • 84862777693 scopus 로고    scopus 로고
    • Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury
    • Pham L. D., Hayakawa K., Seo J. H., et al,. (2012) Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury. Glia 60, 875-881.
    • (2012) Glia , vol.60 , pp. 875-881
    • Pham, L.D.1    Hayakawa, K.2    Seo, J.H.3
  • 41
    • 7644244605 scopus 로고    scopus 로고
    • White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion
    • Shibata M., Ohtani R., Ihara M., and, Tomimoto H., (2004) White matter lesions and glial activation in a novel mouse model of chronic cerebral hypoperfusion. Stroke 35, 2598-2603.
    • (2004) Stroke , vol.35 , pp. 2598-2603
    • Shibata, M.1    Ohtani, R.2    Ihara, M.3    Tomimoto, H.4
  • 42
    • 0742288565 scopus 로고    scopus 로고
    • Regeneration beyond the glial scar
    • Silver J., and, Miller J. H., (2004) Regeneration beyond the glial scar. Nat. Rev. Neurosci. 5, 146-156.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 146-156
    • Silver, J.1    Miller, J.H.2
  • 43
    • 65649106234 scopus 로고    scopus 로고
    • A white matter stroke model in the mouse: Axonal damage, progenitor responses and MRI correlates
    • Sozmen E. G., Kolekar A., Havton L. A., and, Carmichael S. T., (2009) A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates. J. Neurosci. Methods 180, 261-272.
    • (2009) J. Neurosci. Methods , vol.180 , pp. 261-272
    • Sozmen, E.G.1    Kolekar, A.2    Havton, L.A.3    Carmichael, S.T.4
  • 44
    • 0028354917 scopus 로고
    • Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum
    • Strauss S., Otten U., Joggerst B., Pluss K., and, Volk B., (1994) Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum. Neurosci. Lett. 168, 193-196.
    • (1994) Neurosci. Lett. , vol.168 , pp. 193-196
    • Strauss, S.1    Otten, U.2    Joggerst, B.3    Pluss, K.4    Volk, B.5
  • 45
    • 4043052443 scopus 로고    scopus 로고
    • Administration of CD34 + cells after stroke enhances neurogenesis via angiogenesis in a mouse model
    • Taguchi A., Soma T., Tanaka H., et al,. (2004) Administration of CD34 + cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J. Clin. Invest. 114, 330-338.
    • (2004) J. Clin. Invest. , vol.114 , pp. 330-338
    • Taguchi, A.1    Soma, T.2    Tanaka, H.3
  • 46
    • 35348860696 scopus 로고    scopus 로고
    • Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
    • Tang S. C., Arumugam T. V., Xu X., et al,. (2007) Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc. Natl Acad. Sci. USA 104, 13798-13803.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 13798-13803
    • Tang, S.C.1    Arumugam, T.V.2    Xu, X.3
  • 48
  • 49
    • 0015838278 scopus 로고
    • The activities of butyrylcholinesterase and carbonic anhydrase, the rate of anaerobic glycolysis, and the question of a constant density of glial cells in cerebral cortices of various mammalian species from mouse to whale
    • Tower D. B., and, Young O. M., (1973) The activities of butyrylcholinesterase and carbonic anhydrase, the rate of anaerobic glycolysis, and the question of a constant density of glial cells in cerebral cortices of various mammalian species from mouse to whale. J. Neurochem. 20, 269-278.
    • (1973) J. Neurochem. , vol.20 , pp. 269-278
    • Tower, D.B.1    Young, O.M.2
  • 50
    • 0141750710 scopus 로고    scopus 로고
    • High mobility group 1 B-box mediates activation of human endothelium
    • Treutiger C. J., Mullins G. E., Johansson A. S., et al,. (2003) High mobility group 1 B-box mediates activation of human endothelium. J. Intern. Med. 254, 375-385.
    • (2003) J. Intern. Med. , vol.254 , pp. 375-385
    • Treutiger, C.J.1    Mullins, G.E.2    Johansson, A.S.3
  • 51
    • 26844525184 scopus 로고    scopus 로고
    • Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells
    • Urbich C., Aicher A., Heeschen C., Dernbach E., Hofmann W. K., Zeiher A. M., and, Dimmeler S., (2005) Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. J. Mol. Cell. Cardiol. 39, 733-742.
    • (2005) J. Mol. Cell. Cardiol. , vol.39 , pp. 733-742
    • Urbich, C.1    Aicher, A.2    Heeschen, C.3    Dernbach, E.4    Hofmann, W.K.5    Zeiher, A.M.6    Dimmeler, S.7
  • 52
    • 36849030286 scopus 로고    scopus 로고
    • Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study
    • Verdelho A., Madureira S., Ferro J. M., et al,. (2007) Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J. Neurol. Neurosurg. Psychiatry 78, 1325-1330.
    • (2007) J. Neurol. Neurosurg. Psychiatry , vol.78 , pp. 1325-1330
    • Verdelho, A.1    Madureira, S.2    Ferro, J.M.3
  • 53
    • 1542425338 scopus 로고    scopus 로고
    • Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination
    • Woodruff R. H., Fruttiger M., Richardson W. D., and, Franklin R. J., (2004) Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Mol. Cell. Neurosci. 25, 252-262.
    • (2004) Mol. Cell. Neurosci. , vol.25 , pp. 252-262
    • Woodruff, R.H.1    Fruttiger, M.2    Richardson, W.D.3    Franklin, R.J.4
  • 55
    • 39449111508 scopus 로고    scopus 로고
    • Neurovascular signalling defects in neurodegeneration
    • Zacchigna S., Lambrechts D., and, Carmeliet P., (2008) Neurovascular signalling defects in neurodegeneration. Nat. Rev. Neurosci. 9, 169-181.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 169-181
    • Zacchigna, S.1    Lambrechts, D.2    Carmeliet, P.3
  • 56
    • 64349107251 scopus 로고    scopus 로고
    • Neurorestorative therapies for stroke: Underlying mechanisms and translation to the clinic
    • Zhang Z. G., and, Chopp M., (2009) Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic. Lancet Neurol. 8, 491-500.
    • (2009) Lancet Neurol. , vol.8 , pp. 491-500
    • Zhang, Z.G.1    Chopp, M.2
  • 57
    • 38149090292 scopus 로고    scopus 로고
    • The blood-brain barrier in health and chronic neurodegenerative disorders
    • Zlokovic B. V., (2008) The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57, 178-201.
    • (2008) Neuron , vol.57 , pp. 178-201
    • Zlokovic, B.V.1
  • 58
    • 59349106603 scopus 로고    scopus 로고
    • Inflammation and the neurovascular unit in the setting of focal cerebral ischemia
    • del Zoppo G. J., (2009) Inflammation and the neurovascular unit in the setting of focal cerebral ischemia. Neuroscience 158, 972-982.
    • (2009) Neuroscience , vol.158 , pp. 972-982
    • Del Zoppo, G.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.