Regulation of neuregulin expression in the injured rat brain and cultured astrocytes

Journal of Neuroscience

Volumn 21, Issue 4, 2001, Pages 1257-1264

  Tokita, Yoshihito ^a   Keino, Hiroomi ^a   Matsui, Fumiko ^a   Aono, Sachiko ^a   Ishiguro, Hiroshi ^b   Higashiyama, Shigeki ^c   Oohira, Atsuhiko ^a  

^a INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Astrocyte; ErbB2; ErbB3; Forskolin; Neuregulin; Protein kinase A; Trauma

Indexed keywords

CYCLIC AMP; FORSKOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; NEU DIFFERENTIATION FACTOR; PHORBOL ESTER DERIVATIVE; PROTEIN ANTIBODY; PROTEIN KINASE C; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN INJURY; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INACTIVATION; GENE EXPRESSION REGULATION; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 0035866071     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-04-01257.2001     Document Type: Article

References (52)

1. Effects of GGF/neuregulins on neuronal survival and neurite outgrowth correlate with erbB2/neu expression in developing rat retina
2. Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor
3. The neuregulin, glial growth factor 2, diminishes autoimmune demyelination and enhances remyelination in a chronic relapsing model for multiple sclerosis
4. GGF/neuregulin is a neuronal signal that promotes proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors
5. Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration
6. Expression of multiple neuregulin transcripts in postnatal rat brains
7. Expression of neurotrophins and their receptors in primary astroglial cultures: Induction by cyclic AMP-elevating agents
8. Differential expression of ARIA isoforms in the rat brain
9. Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain
10. ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family
11. Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds
12. Localization of basic fibroblast growth factor and its mRNA after CNS injury
13. The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading
14. Expression and characterization of transforming growth factor a precursor protein in transfected mammalian cells
15. A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4
16. Injury-induced regulation of CNTF mRNA in the adult rat brain
17. A metalloprotease-disintegrin, MDC9/meltrin-γ/ADAM9 and PKC δ are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor
18. Fluorescence measurement of changes in intracellular calcium induced by excitatory amino acids in cultured cortical astrocytes
19. Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression
20. Glial growth factor rescues Schwann cells of mechanoreceptors from denervation-induced apoptosis
21. Differences between phosphotyrosine accumulation and Neu/ErbB-2 receptor expression in astrocytic proliferative processes. Implications for glial oncogenesis
22. Transforming growth factor-β1 in the rat brain: Increase after injury and inhibition of astrocyte proliferation
23. The neuregulin precursor proARIA is processed to ARIA after expression on the cell surface by a protein kinase C-enhanced mechanism
24. Expression patterns of transmembrane and released forms of neuregulin during spinal cord and neuromuscular synapse development
25. Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
26. Neuregulins as potential drugs for neurological disorders
27. Receptor-mediated phosphorylation of astroglial intermediate filament proteins in cultured astroglia
28. Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development
29. Neurotrophin receptors in the somatosensory cortex of the mature rat: Co-localization of p75, trk, isoforms, and c-neu
30. Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytes
31. Recombinant human epidermal growth factor precursor is a glycosylated membrane protein with biological activity
32. Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells
33. Transient expression of the juvenile form of neurocan after brain injury of the adult rat
34. Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21
35. Neuregulin-β induces expression of an NMDA-receptor subunit
36. Cell-type specific interaction of Neu differentiation factor (NDF/ heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships
37. Brain neurons and glial cells express Neu differentiation factor/heregulin: A survival factor for astrocytes
38. The glial scar: Its bearing on axon elongation and transplantation approaches to CNS repair
39. Regulation of ciliary neurotrophic factor in cultured rat hippocampal astrocytes
40. Changes in neurotrophic factor expression and receptor activation following exposure of hippocampal neuron/astrocyte cocultures to kainic acid
41. ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses
42. Biochemical and ultrastructural studies of cultured rat astroglial cells: Effect of brain extract and dibutyryl cyclic AMP on glial fibrillary acidic protein and glial filaments
43. Alternative neural crest cell fates are instructively promoted by TGF-β superfamily members
44. Expression of adrenergic receptors in individual astrocytes and motor neurons isolated from rat brain
45. Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve
46. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro
47. Integral membrane glycoprotein properties of the prohormone pro-transforming growth factor-α
48. A role for the acetylcholine receptor-inducing protein ARIA in oligodendrocyte development
49. Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
50. Protein kinase C: Is its pivotal role in cellular activation over-stated?
51. A cysteine-rich isoform of neuregulin controls the level of expression of neuronal nicotinic receptor channels during synaptogenesis
52. Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury