A Non-Synonymous Coding Variant (L616F) in the TLR5 Gene Is Potentially Associated with Crohn's Disease and Influences Responses to Bacterial Flagellin

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Sheridan, Jared ^a   Mack, David R ^b   Amre, Devendra K ^c,d   Israel, David M ^e   Cherkasov, Artem ^f   Li, Huifang ^f   Grimard, Guy ^c,d   Steiner, Theodore S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^c UNIVERSITY OF MONTREAL   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e BC CHILDREN S HOSPITAL   (Canada)

^f VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; TOLL LIKE RECEPTOR 5;

ALLELE; ARTICLE; CANADIAN; CELL STRAIN HEK293; CHILD; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; ETHNIC GROUP; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; TOLL LIKE RECEPTOR 5 GENE;

CANADA; CASE-CONTROL STUDIES; CHEMOKINE CCL20; CROHN DISEASE; FLAGELLIN; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HEK293 CELLS; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 5;

BACTERIA (MICROORGANISMS);

EID: 84876098777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0061326     Document Type: Article

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