-
1
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in thailand
-
MOPH-TAVEG Investigators
-
Rerks-Ngarm, S., P. Pitisuttithum, S. Nitayaphan, J. Kaewkungwal, J. Chiu, R. Paris, N. Premsri, C. Namwat, M. de Souza, E. Adams, et al; MOPH-TAVEG Investigators. 2009. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361: 2209-2220.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
Kaewkungwal, J.4
Chiu, J.5
Paris, R.6
Premsri, N.7
Namwat, C.8
De Souza, M.9
Adams, E.10
-
2
-
-
84856482137
-
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys
-
Barouch, D. H., J. Liu, H. Li, L. F. Maxfield, P. Abbink, D. M. Lynch, M. J. Iampietro, A. SanMiguel, M. S. Seaman, G. Ferrari, et al. 2012. Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys. Nature 482: 89-93.
-
(2012)
Nature
, vol.482
, pp. 89-93
-
-
Barouch, D.H.1
Liu, J.2
Li, H.3
Maxfield, L.F.4
Abbink, P.5
Lynch, D.M.6
Iampietro, M.J.7
SanMiguel, A.8
Seaman, M.S.9
Ferrari, G.10
-
3
-
-
79957618772
-
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
-
Hansen, S. G., J. C. Ford, M. S. Lewis, A. B. Ventura, C. M. Hughes, L. Coyne-Johnson, N. Whizin, K. Oswald, R. Shoemaker, T. Swanson, et al. 2011. Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine. Nature 473: 523-527.
-
(2011)
Nature
, vol.473
, pp. 523-527
-
-
Hansen, S.G.1
Ford, J.C.2
Lewis, M.S.3
Ventura, A.B.4
Hughes, C.M.5
Coyne-Johnson, L.6
Whizin, N.7
Oswald, K.8
Shoemaker, R.9
Swanson, T.10
-
4
-
-
79960565908
-
Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: Efficacy against repeated mucosal R5 clade C SHIV challenges
-
Lakhashe, S. K., V. Velu, G. Sciaranghella, N. B. Siddappa, J. M. Dipasquale, G. Hemashettar, J. K. Yoon, R. A. Rasmussen, F. Yang, S. J. Lee, et al. 2011. Prime-boost vaccination with heterologous live vectors encoding SIV gag and multimeric HIV-1 gp160 protein: efficacy against repeated mucosal R5 clade C SHIV challenges. Vaccine 29: 5611-5622.
-
(2011)
Vaccine
, vol.29
, pp. 5611-5622
-
-
Lakhashe, S.K.1
Velu, V.2
Sciaranghella, G.3
Siddappa, N.B.4
Dipasquale, J.M.5
Hemashettar, G.6
Yoon, J.K.7
Rasmussen, R.A.8
Yang, F.9
Lee, S.J.10
-
5
-
-
67049086871
-
Heterologous prime-boost vaccination
-
Lu, S. 2009. Heterologous prime-boost vaccination. Curr. Opin. Immunol. 21: 346-351.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 346-351
-
-
Lu, S.1
-
6
-
-
69549119958
-
Novel adjuvants for B cell immune responses
-
Loré, K., and G. B. Karlsson Hedestam. 2009. Novel adjuvants for B cell immune responses. Curr Opin HIV AIDS 4: 441-446.
-
(2009)
Curr Opin HIV AIDS
, vol.4
, pp. 441-446
-
-
Loré, K.1
Karlsson Hedestam, G.B.2
-
7
-
-
77958498224
-
Vaccine adjuvants: Putting innate immunity to work
-
Coffman, R. L., A. Sher, and R. A. Seder. 2010. Vaccine adjuvants: putting innate immunity to work. Immunity 33: 492-503.
-
(2010)
Immunity
, vol.33
, pp. 492-503
-
-
Coffman, R.L.1
Sher, A.2
Seder, R.A.3
-
8
-
-
80052422744
-
Subunit vaccines of the future: The need for safe, customized and optimized particulate delivery systems
-
Foged, C. 2011. Subunit vaccines of the future: the need for safe, customized and optimized particulate delivery systems. Ther. Deliv. 2: 1057-1077.
-
(2011)
Ther. Deliv.
, vol.2
, pp. 1057-1077
-
-
Foged, C.1
-
9
-
-
77955597687
-
Unmet needs in modern vaccinology: Adjuvants to improve the immune response
-
Leroux-Roels, G. 2010. Unmet needs in modern vaccinology: adjuvants to improve the immune response. Vaccine 28(Suppl 3): C25-C36.
-
(2010)
Vaccine
, vol.28
, Issue.SUPPL. 3
-
-
Leroux-Roels, G.1
-
10
-
-
78650576197
-
Use of defined TLR ligands as adjuvants within human vaccines
-
Duthie, M. S., H. P. Windish, C. B. Fox, and S. G. Reed. 2011. Use of defined TLR ligands as adjuvants within human vaccines. Immunol. Rev. 239: 178-196.
-
(2011)
Immunol. Rev.
, vol.239
, pp. 178-196
-
-
Duthie, M.S.1
Windish, H.P.2
Fox, C.B.3
Reed, S.G.4
-
11
-
-
78651410969
-
Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine
-
Luke, J. M., G. G. Simon, J. Söderholm, J. S. Errett, J. T. August, M. Gale, Jr., C. P. Hodgson, and J. A. Williams. 2011. Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine. J. Virol. 85: 1370-1383.
-
(2011)
J. Virol.
, vol.85
, pp. 1370-1383
-
-
Luke, J.M.1
Simon, G.G.2
Söderholm, J.3
Errett, J.S.4
August, J.T.5
Gale Jr., M.6
Hodgson, C.P.7
Williams, J.A.8
-
12
-
-
39149125164
-
Type I interferon as a stimulus for cross-priming
-
Le Bon, A., and D. F. Tough. 2008. Type I interferon as a stimulus for cross-priming. Cytokine Growth Factor Rev. 19: 33-40.
-
(2008)
Cytokine Growth Factor Rev.
, vol.19
, pp. 33-40
-
-
Le Bon, A.1
Tough, D.F.2
-
13
-
-
79955505656
-
Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets
-
Kastenmüller, K., U. Wille-Reece, R. W. Lindsay, L. R. Trager, P. A. Darrah, B. J. Flynn, M. R. Becker, M. C. Udey, B. E. Clausen, B. Z. Igyarto, et al. 2011. Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets. J. Clin. Invest. 121: 1782-1796.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1782-1796
-
-
Kastenmüller, K.1
Wille-Reece, U.2
Lindsay, R.W.3
Trager, L.R.4
Darrah, P.A.5
Flynn, B.J.6
Becker, M.R.7
Udey, M.C.8
Clausen, B.E.9
Igyarto, B.Z.10
-
14
-
-
84864020108
-
Signal 3 cytokines as modulators of primary immune responses during infections: The interplay of type I IFN and IL-12 in CD8 T cell responses
-
Keppler, S. J., K. Rosenits, T. Koegl, S. Vucikuja, and P. Aichele. 2012. Signal 3 cytokines as modulators of primary immune responses during infections: the interplay of type I IFN and IL-12 in CD8 T cell responses. PLoS ONE 7: e40865.
-
(2012)
PLoS ONE
, vol.7
-
-
Keppler, S.J.1
Rosenits, K.2
Koegl, T.3
Vucikuja, S.4
Aichele, P.5
-
15
-
-
23944489407
-
Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani, G., A. Rinaldi, F. Bertoni, F. Sallusto, and A. Lanzavecchia. 2005. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6: 769-776.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
16
-
-
79952173864
-
Programming the magnitude and persistence of antibody responses with innate immunity
-
Kasturi, S. P., I. Skountzou, R. A. Albrecht, D. Koutsonanos, T. Hua, H. I. Nakaya, R. Ravindran, S. Stewart, M. Alam, M. Kwissa, et al. 2011. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 470: 543-547.
-
(2011)
Nature
, vol.470
, pp. 543-547
-
-
Kasturi, S.P.1
Skountzou, I.2
Albrecht, R.A.3
Koutsonanos, D.4
Hua, T.5
Nakaya, H.I.6
Ravindran, R.7
Stewart, S.8
Alam, M.9
Kwissa, M.10
-
17
-
-
33646697743
-
Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates
-
Wille-Reece, U., B. J. Flynn, K. Loré, R. A. Koup, A. P. Miles, A. Saul, R. M. Kedl, J. J. Mattapallil, W. R. Weiss, M. Roederer, and R. A. Seder. 2006. Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates. J. Exp. Med. 203: 1249-1258.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1249-1258
-
-
Wille-Reece, U.1
Flynn, B.J.2
Loré, K.3
Koup, R.A.4
Miles, A.P.5
Saul, A.6
Kedl, R.M.7
Mattapallil, J.J.8
Weiss, W.R.9
Roederer, M.10
Seder, R.A.11
-
18
-
-
79955551576
-
Immunization with HIV gag targeted to dendritic cells followed by recombinant new york vaccinia virus induces robust T-cell immunity in nonhuman primates
-
Flynn, B. J., K. Kastenmüller, U. Wille-Reece, G. D. Tomaras, M. Alam, R. W. Lindsay, A. M. Salazar, B. Perdiguero, C. E. Gomez, R. Wagner, et al. 2011. Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc. Natl. Acad. Sci. USA 108: 7131-7136.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7131-7136
-
-
Flynn, B.J.1
Kastenmüller, K.2
Wille-Reece, U.3
Tomaras, G.D.4
Alam, M.5
Lindsay, R.W.6
Salazar, A.M.7
Perdiguero, B.8
Gomez, C.E.9
Wagner, R.10
-
19
-
-
77956020496
-
Immunization with wild-type or CD4-binding-defective HIV-1 env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus
-
Sundling, C., S. O'Dell, I. Douagi, M. N. Forsell, A. Mörner, K. Loré, J. R. Mascola, R. T. Wyatt, and G. B. Karlsson Hedestam. 2010. Immunization with wild-type or CD4-binding-defective HIV-1 Env trimers reduces viremia equivalently following heterologous challenge with simian-human immunodeficiency virus. J. Virol. 84: 9086-9095.
-
(2010)
J. Virol.
, vol.84
, pp. 9086-9095
-
-
Sundling, C.1
O'Dell, S.2
Douagi, I.3
Forsell, M.N.4
Mörner, A.5
Loré, K.6
Mascola, J.R.7
Wyatt, R.T.8
Karlsson Hedestam, G.B.9
-
20
-
-
84859818500
-
Evaluation of immune responses to a plasmodium vivax CSP-based recombinant protein vaccine candidate in combination with second-generation adjuvants in mice
-
Lumsden, J. M., S. Nurmukhambetova, J. H. Klein, J. Sattabongkot, J. W. Bennett, S. Bertholet, C. B. Fox, S. G. Reed, C. F. Ockenhouse, R. F. Howard, et al. 2012. Evaluation of immune responses to a Plasmodium vivax CSP-based recombinant protein vaccine candidate in combination with second-generation adjuvants in mice. Vaccine 30: 3311-3319.
-
(2012)
Vaccine
, vol.30
, pp. 3311-3319
-
-
Lumsden, J.M.1
Nurmukhambetova, S.2
Klein, J.H.3
Sattabongkot, J.4
Bennett, J.W.5
Bertholet, S.6
Fox, C.B.7
Reed, S.G.8
Ockenhouse, C.F.9
Howard, R.F.10
-
21
-
-
0141923686
-
Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
-
Loré, K., M. R. Betts, J. M. Brenchley, J. Kuruppu, S. Khojasteh, S. Perfetto, M. Roederer, R. A. Seder, and R. A. Koup. 2003. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses. J. Immunol. 171: 4320-4328.
-
(2003)
J. Immunol.
, vol.171
, pp. 4320-4328
-
-
Loré, K.1
Betts, M.R.2
Brenchley, J.M.3
Kuruppu, J.4
Khojasteh, S.5
Perfetto, S.6
Roederer, M.7
Seder, R.A.8
Koup, R.A.9
-
22
-
-
33644752743
-
Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells
-
Ito, T., H. Kanzler, O. Duramad, W. Cao, and Y. J. Liu. 2006. Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells. Blood 107: 2423-2431.
-
(2006)
Blood
, vol.107
, pp. 2423-2431
-
-
Ito, T.1
Kanzler, H.2
Duramad, O.3
Cao, W.4
Liu, Y.J.5
-
23
-
-
0037013830
-
Interferon-alpha and interleukin-12 are induced differentially by toll-like receptor 7 ligands in human blood dendritic cell subsets
-
Ito, T., R. Amakawa, T. Kaisho, H. Hemmi, K. Tajima, K. Uehira, Y. Ozaki, H. Tomizawa, S. Akira, and S. Fukuhara. 2002. Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J. Exp. Med. 195: 1507-1512.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1507-1512
-
-
Ito, T.1
Amakawa, R.2
Kaisho, T.3
Hemmi, H.4
Tajima, K.5
Uehira, K.6
Ozaki, Y.7
Tomizawa, H.8
Akira, S.9
Fukuhara, S.10
-
24
-
-
0033041954
-
Efficient generation of recombinant adenoviral vectors by cre-lox recombination in vitro
-
Aoki, K., C. Barker, X. Danthinne, M. J. Imperiale, and G. J. Nabel. 1999. Efficient generation of recombinant adenoviral vectors by Cre-lox recombination in vitro. Mol. Med. 5: 224-231.
-
(1999)
Mol. Med.
, vol.5
, pp. 224-231
-
-
Aoki, K.1
Barker, C.2
Danthinne, X.3
Imperiale, M.J.4
Nabel, G.J.5
-
25
-
-
79956107362
-
Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses
-
Asmal, M., Y. Sun, S. Lane, W. Yeh, S. D. Schmidt, J. R. Mascola, and N. L. Letvin. 2011. Antibody-dependent cell-mediated viral inhibition emerges after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys coincident with gp140-binding antibodies and is effective against neutralization-resistant viruses. J. Virol. 85: 5465-5475.
-
(2011)
J. Virol.
, vol.85
, pp. 5465-5475
-
-
Asmal, M.1
Sun, Y.2
Lane, S.3
Yeh, W.4
Schmidt, S.D.5
Mascola, J.R.6
Letvin, N.L.7
-
26
-
-
16644389382
-
Multicolor flow cytometric analysis in SIV-infected rhesus macaque
-
Walker, J. M., H. T. Maecker, V. C. Maino, and L. J. Picker. 2004. Multicolor flow cytometric analysis in SIV-infected rhesus macaque. Methods Cell Biol. 75: 535-557.
-
(2004)
Methods Cell Biol.
, vol.75
, pp. 535-557
-
-
Walker, J.M.1
Maecker, H.T.2
Maino, V.C.3
Picker, L.J.4
-
27
-
-
23844524271
-
Highly sensitive SIV plasma viral load assay: Practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS
-
Cline, A. N., J. W. Bess, M. Piatak, Jr., and J. D. Lifson. 2005. Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS. J. Med. Primatol. 34: 303-312.
-
(2005)
J. Med. Primatol.
, vol.34
, pp. 303-312
-
-
Cline, A.N.1
Bess, J.W.2
Piatak Jr., M.3
Lifson, J.D.4
-
28
-
-
34247585475
-
Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D
-
Abbink, P., A. A. Lemckert, B. A. Ewald, D. M. Lynch, M. Denholtz, S. Smits, L. Holterman, I. Damen, R. Vogels, A. R. Thorner, et al. 2007. Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. J. Virol. 81: 4654-4663.
-
(2007)
J. Virol.
, vol.81
, pp. 4654-4663
-
-
Abbink, P.1
Lemckert, A.A.2
Ewald, B.A.3
Lynch, D.M.4
Denholtz, M.5
Smits, S.6
Holterman, L.7
Damen, I.8
Vogels, R.9
Thorner, A.R.10
-
29
-
-
15444357765
-
*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus
-
*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus. J. Immunol. 160: 6062-6071.
-
(1998)
J. Immunol.
, vol.160
, pp. 6062-6071
-
-
Allen, T.M.1
Sidney, J.2
Del Guercio, M.F.3
Glickman, R.L.4
Lensmeyer, G.L.5
Wiebe, D.A.6
DeMars, R.7
Pauza, C.D.8
Johnson, R.P.9
Sette, A.10
Watkins, D.I.11
-
30
-
-
33845595414
-
Alteration of epitope recognition pattern in ag85b and ESAT-6 has a profound influence on vaccine-induced protection against myco-bacterium tuberculosis
-
Bennekov, T., J. Dietrich, I. Rosenkrands, A. Stryhn, T. M. Doherty, and P. Andersen. 2006. Alteration of epitope recognition pattern in Ag85B and ESAT-6 has a profound influence on vaccine-induced protection against Myco-bacterium tuberculosis. Eur. J. Immunol. 36: 3346-3355.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 3346-3355
-
-
Bennekov, T.1
Dietrich, J.2
Rosenkrands, I.3
Stryhn, A.4
Doherty, T.M.5
Andersen, P.6
-
31
-
-
77957562384
-
Simian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV gag capsid
-
Giraldo-Vela, J. P., A. T. Bean, R. Rudersdorf, L. T. Wallace, J. T. Loffredo, P. Erickson, N. A. Wilson, and D. I. Watkins. 2010. Simian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV Gag capsid. Immunogenetics 62: 701-707.
-
(2010)
Immunogenetics
, vol.62
, pp. 701-707
-
-
Giraldo-Vela, J.P.1
Bean, A.T.2
Rudersdorf, R.3
Wallace, L.T.4
Loffredo, J.T.5
Erickson, P.6
Wilson, N.A.7
Watkins, D.I.8
-
32
-
-
70350328590
-
*08-positive macaques
-
*08-positive macaques. J. Virol. 83: 11514-11527.
-
(2009)
J. Virol.
, vol.83
, pp. 11514-11527
-
-
Valentine, L.E.1
Loffredo, J.T.2
Bean, A.T.3
León, E.J.4
MacNair, C.E.5
Beal, D.R.6
Piaskowski, S.M.7
Klimentidis, Y.C.8
Lank, S.M.9
Wiseman, R.W.10
-
33
-
-
50949116449
-
Differential antigen presentation kinetics of CD8+ T-cell epitopes derived from the same viral protein
-
Sacha, J. B., M. R. Reynolds, M. B. Buechler, C. Chung, A. K. Jonas, L. T. Wallace, A. M. Weiler, W. Lee, S. M. Piaskowski, T. Soma, et al. 2008. Differential antigen presentation kinetics of CD8+ T-cell epitopes derived from the same viral protein. J. Virol. 82: 9293-9298.
-
(2008)
J. Virol.
, vol.82
, pp. 9293-9298
-
-
Sacha, J.B.1
Reynolds, M.R.2
Buechler, M.B.3
Chung, C.4
Jonas, A.K.5
Wallace, L.T.6
Weiler, A.M.7
Lee, W.8
Piaskowski, S.M.9
Soma, T.10
-
34
-
-
58149267963
-
Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
-
Liu, J., K. L. O'Brien, D. M. Lynch, N. L. Simmons, A. La Porte, A. M. Riggs, P. Abbink, R. T. Coffey, L. E. Grandpre, M. S. Seaman, et al. 2009. Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457: 87-91.
-
(2009)
Nature
, vol.457
, pp. 87-91
-
-
Liu, J.1
O'Brien, K.L.2
Lynch, D.M.3
Simmons, N.L.4
La Porte, A.5
Riggs, A.M.6
Abbink, P.7
Coffey, R.T.8
Grandpre, L.E.9
Seaman, M.S.10
-
35
-
-
84858419788
-
Beyond empiricism: Informing vaccine development through innate immunity research
-
Levitz, S. M., and D. T. Golenbock. 2012. Beyond empiricism: informing vaccine development through innate immunity research. Cell 148: 1284-1292.
-
(2012)
Cell
, vol.148
, pp. 1284-1292
-
-
Levitz, S.M.1
Golenbock, D.T.2
-
36
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil, F., H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer. 2004. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303: 1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
37
-
-
84868547474
-
Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques
-
Stahl-Hennig, C., M. Eisenblätter, E. Jasny, T. Rzehak, K. Tenner-Racz, C. Trumpfheller, A. M. Salazar, K. Uberla, K. Nieto, J. Kleinschmidt, et al. 2009. Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques. PLoS Pathog. 5: e1000373.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Stahl-Hennig, C.1
Eisenblätter, M.2
Jasny, E.3
Rzehak, T.4
Tenner-Racz, K.5
Trumpfheller, C.6
Salazar, A.M.7
Uberla, K.8
Nieto, K.9
Kleinschmidt, J.10
-
38
-
-
77957753966
-
Poly(I:C) Is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to plasmodium falciparum circumsporozoite protein (CSP) and aDEC-CSP in non human primates
-
Tewari, K., B. J. Flynn, S. B. Boscardin, K. Kastenmueller, A. M. Salazar, C. A. Anderson, V. Soundarapandian, A. Ahumada, T. Keler, S. L. Hoffman, et al. 2010. Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and aDEC-CSP in non human primates. Vaccine 28: 7256-7266.
-
(2010)
Vaccine
, vol.28
, pp. 7256-7266
-
-
Tewari, K.1
Flynn, B.J.2
Boscardin, S.B.3
Kastenmueller, K.4
Salazar, A.M.5
Anderson, C.A.6
Soundarapandian, V.7
Ahumada, A.8
Keler, T.9
Hoffman, S.L.10
-
39
-
-
27244443079
-
HIV gag protein conjugated to a toll-like receptor 7/8 agonist improves the magnitude and quality of th1 and CD8+ T cell responses in nonhuman primates
-
Wille-Reece, U., B. J. Flynn, K. Loré, R. A. Koup, R. M. Kedl, J. J. Mattapallil, W. R. Weiss, M. Roederer, and R. A. Seder. 2005. HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proc. Natl. Acad. Sci. USA 102: 15190-15194.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15190-15194
-
-
Wille-Reece, U.1
Flynn, B.J.2
Loré, K.3
Koup, R.A.4
Kedl, R.M.5
Mattapallil, J.J.6
Weiss, W.R.7
Roederer, M.8
Seder, R.A.9
-
40
-
-
67649216110
-
Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells
-
Lindenstrøm, T., E. M. Agger, K. S. Korsholm, P. A. Darrah, C. Aagaard, R. A. Seder, I. Rosenkrands, and P. Andersen. 2009. Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J. Immunol. 182: 8047-8055.
-
(2009)
J. Immunol.
, vol.182
, pp. 8047-8055
-
-
Lindenstrøm, T.1
Agger, E.M.2
Korsholm, K.S.3
Darrah, P.A.4
Aagaard, C.5
Seder, R.A.6
Rosenkrands, I.7
Andersen, P.8
-
41
-
-
34250303350
-
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against leishmania major
-
Darrah, P. A., D. T. Patel, P. M. De Luca, R. W. Lindsay, D. F. Davey, B. J. Flynn, S. T. Hoff, P. Andersen, S. G. Reed, S. L. Morris, et al. 2007. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat. Med. 13: 843-850.
-
(2007)
Nat. Med.
, vol.13
, pp. 843-850
-
-
Darrah, P.A.1
Patel, D.T.2
De Luca, P.M.3
Lindsay, R.W.4
Davey, D.F.5
Flynn, B.J.6
Hoff, S.T.7
Andersen, P.8
Reed, S.G.9
Morris, S.L.10
-
42
-
-
67650445798
-
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ th1 immunity with poly IC as adjuvant
-
Longhi, M. P., C. Trumpfheller, J. Idoyaga, M. Caskey, I. Matos, C. Kluger, A. M. Salazar, M. Colonna, and R. M. Steinman. 2009. Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206: 1589-1602.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1589-1602
-
-
Longhi, M.P.1
Trumpfheller, C.2
Idoyaga, J.3
Caskey, M.4
Matos, I.5
Kluger, C.6
Salazar, A.M.7
Colonna, M.8
Steinman, R.M.9
-
43
-
-
48749103238
-
Impact of MHC class I diversity on immune control of immunodeficiency virus replication
-
Goulder, P. J., and D. I. Watkins. 2008. Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat. Rev. Immunol. 8: 619-630.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 619-630
-
-
Goulder, P.J.1
Watkins, D.I.2
-
44
-
-
0036686398
-
CpG-DNA aided cross-presentation of soluble antigens by dendritic cells
-
Maurer, T., A. Heit, H. Hochrein, F. Ampenberger, M. O'Keeffe, S. Bauer, G. B. Lipford, R. M. Vabulas, and H. Wagner. 2002. CpG-DNA aided cross-presentation of soluble antigens by dendritic cells. Eur. J. Immunol. 32: 2356-2364.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2356-2364
-
-
Maurer, T.1
Heit, A.2
Hochrein, H.3
Ampenberger, F.4
O'Keeffe, M.5
Bauer, S.6
Lipford, G.B.7
Vabulas, R.M.8
Wagner, H.9
-
45
-
-
78049511069
-
The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity
-
Oh, J. Z., and R. M. Kedl. 2010. The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity. J. Immunol. 185: 4602-4608.
-
(2010)
J. Immunol.
, vol.185
, pp. 4602-4608
-
-
Oh, J.Z.1
Kedl, R.M.2
-
46
-
-
61749101016
-
The immunogenicity of CpG-antigen conjugates
-
Wagner, H. 2009. The immunogenicity of CpG-antigen conjugates. Adv. Drug Deliv. Rev. 61: 243-247.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 243-247
-
-
Wagner, H.1
-
47
-
-
84855913888
-
New paradigms for HIV/AIDS vaccine development
-
Picker, L. J., S. G. Hansen, and J. D. Lifson. 2012. New paradigms for HIV/AIDS vaccine development. Annu. Rev. Med. 63: 95-111.
-
(2012)
Annu. Rev. Med.
, vol.63
, pp. 95-111
-
-
Picker, L.J.1
Hansen, S.G.2
Lifson, J.D.3
-
48
-
-
4444316121
-
Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein
-
Staprans, S. I., A. P. Barry, G. Silvestri, J. T. Safrit, N. Kozyr, B. Sumpter, H. Nguyen, H. McClure, D. Montefiori, J. I. Cohen, and M. B. Feinberg. 2004. Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein. Proc. Natl. Acad. Sci. USA 101: 13026-13031.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13026-13031
-
-
Staprans, S.I.1
Barry, A.P.2
Silvestri, G.3
Safrit, J.T.4
Kozyr, N.5
Sumpter, B.6
Nguyen, H.7
McClure, H.8
Montefiori, D.9
Cohen, J.I.10
Feinberg, M.B.11
-
49
-
-
77950858633
-
Cytolytic CD4 cells: Direct mediators in infectious disease and malignancy
-
Brown, D. M. 2010. Cytolytic CD4 cells: Direct mediators in infectious disease and malignancy. Cell. Immunol. 262: 89-95.
-
(2010)
Cell. Immunol.
, vol.262
, pp. 89-95
-
-
Brown, D.M.1
-
50
-
-
84857751302
-
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
-
Soghoian, D. Z., H. Jessen, M. Flanders, K. Sierra-Davidson, S. Cutler, T. Pertel, S. Ranasinghe, M. Lindqvist, I. Davis, K. Lane, J. Rychert, E. S. Rosenberg, A. Piechocka-Trocha, A. L. Brass, J. M. Brenchley, B. D. Walker, and H. Streeck 2012. HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome. Sci. Transl. Med. 4: 123ra125.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Soghoian, D.Z.1
Jessen, H.2
Flanders, M.3
Sierra-Davidson, K.4
Cutler, S.5
Pertel, T.6
Ranasinghe, S.7
Lindqvist, M.8
Davis, I.9
Lane, K.10
Rychert, J.11
Rosenberg, E.S.12
Piechocka-Trocha, A.13
Brass, A.L.14
Brenchley, J.M.15
Walker, B.D.16
Streeck, H.17
-
51
-
-
67649849924
-
Gag-and nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection
-
Sacha, J. B., J. P. Giraldo-Vela, M. B. Buechler, M. A. Martins, N. J. Maness, C. Chung, L. T. Wallace, E. J. León, T. C. Friedrich, N. A. Wilson, et al. 2009. Gag-and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection. Proc. Natl. Acad. Sci. USA 106: 9791-9796.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9791-9796
-
-
Sacha, J.B.1
Giraldo-Vela, J.P.2
Buechler, M.B.3
Martins, M.A.4
Maness, N.J.5
Chung, C.6
Wallace, L.T.7
León, E.J.8
Friedrich, T.C.9
Wilson, N.A.10
-
52
-
-
0035030376
-
Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
-
Le Bon, A., G. Schiavoni, G. D'Agostino, I. Gresser, F. Belardelli, and D. F. Tough. 2001. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14: 461-470.
-
(2001)
Immunity
, vol.14
, pp. 461-470
-
-
Le Bon, A.1
Schiavoni, G.2
D'Agostino, G.3
Gresser, I.4
Belardelli, F.5
Tough, D.F.6
-
53
-
-
33645775256
-
Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming
-
Le Bon, A., V. Durand, E. Kamphuis, C. Thompson, S. Bulfone-Paus, C. Rossmann, U. Kalinke, and D. F. Tough. 2006. Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming. J. Immunol. 176: 4682-4689.
-
(2006)
J. Immunol.
, vol.176
, pp. 4682-4689
-
-
Le Bon, A.1
Durand, V.2
Kamphuis, E.3
Thompson, C.4
Bulfone-Paus, S.5
Rossmann, C.6
Kalinke, U.7
Tough, D.F.8
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