-
1
-
-
80051580618
-
Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011;61:212-36.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
2
-
-
15944403227
-
The skin immune system and the challenge of tumour immunosurveillance
-
Woods GM, Malley RC, Muller HK. The skin immune system and the challenge of tumour immunosurveillance. Eur J Dermatol 2005;15: 63-9.
-
(2005)
Eur J Dermatol
, vol.15
, pp. 63-69
-
-
Woods, G.M.1
Malley, R.C.2
Muller, H.K.3
-
3
-
-
0016763636
-
Spontaneous regression of melanoma
-
McGovern VJ. Spontaneous regression of melanoma. Pathology 1975;7:91-9.
-
(1975)
Pathology
, vol.7
, pp. 91-99
-
-
McGovern, V.J.1
-
6
-
-
35748932684
-
Harnessing autoimmunity (vitiligo) to treat melanoma: A myth or reality?
-
Ram M, Shoenfeld Y. Harnessing autoimmunity (vitiligo) to treat melanoma: a myth or reality? Ann N Y Acad Sci 2007;1110:410-25.
-
(2007)
Ann N y Acad Sci
, vol.1110
, pp. 410-425
-
-
Ram, M.1
Shoenfeld, Y.2
-
7
-
-
32944469022
-
Well-defined melanoma antigens as progression markers for melanoma: Insights into differential expression and host response based on stage
-
Hodi FS. Well-defined melanoma antigens as progression markers for melanoma: insights into differential expression and host response based on stage. Clin Cancer Res 2006;12:673-8.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 673-678
-
-
Hodi, F.S.1
-
8
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
Gogas H, Ioannovich J, Dafni U, Stavropoulou-Giokas C, Frangia K, Tsoutsos D, et al. Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 2006;354: 709-18.
-
(2006)
N Engl J Med
, vol.354
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
Stavropoulou-Giokas, C.4
Frangia, K.5
Tsoutsos, D.6
-
9
-
-
0025295238
-
Clinical variation of autoimmune polyendocrinopathy-candidiasis- ectodermal dystrophy (APECED) in a series of 68 patients
-
Ahonen P, Myllarniemi S, Sipila I, Perheentupa J. Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients. N Engl J Med 1990;322:1829-36.
-
(1990)
N Engl J Med
, vol.322
, pp. 1829-1836
-
-
Ahonen, P.1
Myllarniemi, S.2
Sipila, I.3
Perheentupa, J.4
-
10
-
-
49749101709
-
The autoimmune regulator gene (AIRE) is strongly associated with vitiligo
-
Tazi-Ahnini R, McDonagh AJ, Wengraf DA, Lovewell TR, Vasilopoulos Y, Messenger AG, et al. The autoimmune regulator gene (AIRE) is strongly associated with vitiligo. Br J Dermatol 2008;159:591-6.
-
(2008)
Br J Dermatol
, vol.159
, pp. 591-596
-
-
Tazi-Ahnini, R.1
McDonagh, A.J.2
Wengraf, D.A.3
Lovewell, T.R.4
Vasilopoulos, Y.5
Messenger, A.G.6
-
11
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski J, Schulte A, Kyewski B, Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001;2:1032-9.
-
(2001)
Nat Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
12
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002;298:1395-401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
Chen, Z.4
Berzins, S.P.5
Turley, S.J.6
-
13
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nat Immunol 2003;4:350-4.
-
(2003)
Nat Immunol
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
14
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity 2005;23:227-39.
-
(2005)
Immunity
, vol.23
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
15
-
-
67650507153
-
The thymic medulla: A unique microenvironment for intercellular self-antigen transfer
-
Koble C, Kyewski B. The thymic medulla: a unique microenvironment for intercellular self-antigen transfer. J Exp Med 2009;206:1505-13.
-
(2009)
J Exp Med
, vol.206
, pp. 1505-1513
-
-
Koble, C.1
Kyewski, B.2
-
16
-
-
79951715831
-
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
-
Lei Y, Ripen AM, Ishimaru N, Ohigashi I, Nagasawa T, Jeker LT, et al. Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development. J Exp Med 2011;208:383-94.
-
(2011)
J Exp Med
, vol.208
, pp. 383-394
-
-
Lei, Y.1
Ripen, A.M.2
Ishimaru, N.3
Ohigashi, I.4
Nagasawa, T.5
Jeker, L.T.6
-
18
-
-
77953019686
-
The role of AIRE polymorphisms in melanoma
-
Conteduca G, Ferrera F, Pastorino L, Fenoglio D, Negrini S, Sormani MP, et al. The role of AIRE polymorphisms in melanoma. Clin Immunol 2010;136:96-104.
-
(2010)
Clin Immunol
, vol.136
, pp. 96-104
-
-
Conteduca, G.1
Ferrera, F.2
Pastorino, L.3
Fenoglio, D.4
Negrini, S.5
Sormani, M.P.6
-
19
-
-
84859589258
-
The immune response to melanoma is limited by thymic selection of self-antigens
-
Trager U, Sierro S, Djordjevic G, Bouzo B, Khandwala S, Meloni A, et al. The immune response to melanoma is limited by thymic selection of self-antigens. PLoS ONE 2012;7:e35005.
-
(2012)
PLoS ONE
, vol.7
-
-
Trager, U.1
Sierro, S.2
Djordjevic, G.3
Bouzo, B.4
Khandwala, S.5
Meloni, A.6
-
20
-
-
84855370170
-
Minimal tolerance to a tumor antigen encoded by a cancer-germline gene
-
Huijbers IJ, Soudja SM, Uyttenhove C, Buferne M, Inderberg-Suso EM, Colau D, et al. Minimal tolerance to a tumor antigen encoded by a cancer-germline gene. J Immunol 2012;188:111-21.
-
(2012)
J Immunol
, vol.188
, pp. 111-121
-
-
Huijbers, I.J.1
Soudja, S.M.2
Uyttenhove, C.3
Buferne, M.4
Inderberg-Suso, E.M.5
Colau, D.6
-
21
-
-
34548779835
-
Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes
-
Nichols LA, Chen Y, Colella TA, Bennett CL, Clausen BE, Engelhard VH. Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes. J Immunol 2007;179:993-1003.
-
(2007)
J Immunol
, vol.179
, pp. 993-1003
-
-
Nichols, L.A.1
Chen, Y.2
Colella, T.A.3
Bennett, C.L.4
Clausen, B.E.5
Engelhard, V.H.6
-
22
-
-
43049128502
-
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
-
Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, et al. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. J Clin Invest 2008;118:1712-26.
-
(2008)
J Clin Invest
, vol.118
, pp. 1712-1726
-
-
Su, M.A.1
Giang, K.2
Zumer, K.3
Jiang, H.4
Oven, I.5
Rinn, J.L.6
-
23
-
-
84857386356
-
Classic in vivo cancer models: Three examples of mouse models used in experimental therapeutics
-
Chapter 5:Unit5.24
-
Kruczynski A, Hill BT. Classic in vivo cancer models: three examples of mouse models used in experimental therapeutics. Curr Protoc Pharmacol 2002;Chapter 5:Unit5.24.
-
(2002)
Curr Protoc Pharmacol
-
-
Kruczynski, A.1
Hill, B.T.2
-
24
-
-
34250304705
-
Defective antitumor responses in CX3CR1-deficient mice
-
Yu YR, Fong AM, Combadiere C, Gao JL, Murphy PM, Patel DD. Defective antitumor responses in CX3CR1-deficient mice. Int J Cancer 2007;121:316-22.
-
(2007)
Int J Cancer
, vol.121
, pp. 316-322
-
-
Yu, Y.R.1
Fong, A.M.2
Combadiere, C.3
Gao, J.L.4
Murphy, P.M.5
Patel, D.D.6
-
25
-
-
33751513054
-
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
-
De Voss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, et al. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med 2006;203:2727-35.
-
(2006)
J Exp Med
, vol.203
, pp. 2727-2735
-
-
De Voss, J.1
Hou, Y.2
Johannes, K.3
Lu, W.4
Liou, G.I.5
Rinn, J.6
-
26
-
-
80051738735
-
Vitiligo: A comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up
-
Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: a comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up. J Am Acad Dermatol 2011;65:473-91.
-
(2011)
J Am Acad Dermatol
, vol.65
, pp. 473-491
-
-
Alikhan, A.1
Felsten, L.M.2
Daly, M.3
Petronic-Rosic, V.4
-
28
-
-
83455173552
-
IL-10 elicits IFNgamma-dependent tumor immune surveillance
-
Mumm JB, Emmerich J, Zhang X, Chan I, Wu L, Mauze S, et al. IL-10 elicits IFNgamma-dependent tumor immune surveillance. Cancer Cell 2011;20:781-96.
-
(2011)
Cancer Cell
, vol.20
, pp. 781-796
-
-
Mumm, J.B.1
Emmerich, J.2
Zhang, X.3
Chan, I.4
Wu, L.5
Mauze, S.6
-
29
-
-
84863337726
-
+ T cells persist, mediate tumor regression, and acquire central memory phenotype
-
+ T cells persist, mediate tumor regression, and acquire central memory phenotype. Proc Natl Acad Sci U S A 2012;109:4592-7.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 4592-4597
-
-
Chapuis, A.G.1
Thompson, J.A.2
Margolin, K.A.3
Rodmyre, R.4
Lai, I.P.5
Dowdy, K.6
-
30
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, et al. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008;321:843-7.
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
Devoss, J.J.2
Friedman, R.S.3
Wong, D.J.4
Tan, Y.X.5
Zhou, X.6
-
31
-
-
47649122633
-
Tumor-specific Th17-polarized cells eradicate large established melanoma
-
Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 2008;112:362-73.
-
(2008)
Blood
, vol.112
, pp. 362-373
-
-
Muranski, P.1
Boni, A.2
Antony, P.A.3
Cassard, L.4
Irvine, K.R.5
Kaiser, A.6
-
32
-
-
77949530108
-
Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma
-
Xie Y, Akpinarli A, Maris C, Hipkiss EL, Lane M, Kwon EK, et al. Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. J Exp Med 2010;207:651-67.
-
(2010)
J Exp Med
, vol.207
, pp. 651-667
-
-
Xie, Y.1
Akpinarli, A.2
Maris, C.3
Hipkiss, E.L.4
Lane, M.5
Kwon, E.K.6
-
33
-
-
34248550936
-
Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: Implications for selftolerance and tumor therapy
-
Cloosen S, Arnold J, Thio M, Bos GM, Kyewski B, Germeraad WT. Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for selftolerance and tumor therapy. Cancer Res 2007;67:3919-26.
-
(2007)
Cancer Res
, vol.67
, pp. 3919-3926
-
-
Cloosen, S.1
Arnold, J.2
Thio, M.3
Bos, G.M.4
Kyewski, B.5
Germeraad, W.T.6
-
34
-
-
33646165128
-
A central role for central tolerance
-
Kyewski B, Klein L. A central role for central tolerance. Annu Rev Immunol 2006;24:571-606.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 571-606
-
-
Kyewski, B.1
Klein, L.2
-
35
-
-
56149122264
-
Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1
-
Devoss JJ, Shum AK, Johannes KP, Lu W, Krawisz AK, Wang P, et al. Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1. J Immunol 2008;181:4072-9.
-
(2008)
J Immunol
, vol.181
, pp. 4072-4079
-
-
Devoss, J.J.1
Shum, A.K.2
Johannes, K.P.3
Lu, W.4
Krawisz, A.K.5
Wang, P.6
-
36
-
-
51349138423
-
B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients
-
Gavanescu I, Benoist C, Mathis D. B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: a therapeutic approach for APECED patients. Proc Natl Acad Sci U S A 2008;105:13009-14.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13009-13014
-
-
Gavanescu, I.1
Benoist, C.2
Mathis, D.3
-
37
-
-
84870292130
-
Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire)
-
Oliveira EH, Macedo C, Donate PB, Almeida RS, Pezzi N, Nguyen C, et al. Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire). Immunobiology 2013;218:96-104.
-
(2013)
Immunobiology
, vol.218
, pp. 96-104
-
-
Oliveira, E.H.1
Macedo, C.2
Donate, P.B.3
Almeida, R.S.4
Pezzi, N.5
Nguyen, C.6
-
39
-
-
77951069509
-
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
-
Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, et al. Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med 2010;207:681-8.
-
(2010)
J Exp Med
, vol.207
, pp. 681-688
-
-
Cohen, J.N.1
Guidi, C.J.2
Tewalt, E.F.3
Qiao, H.4
Rouhani, S.J.5
Ruddell, A.6
-
40
-
-
7244227646
-
Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
-
Liston A, Gray DH, Lesage S, Fletcher AL, Wilson J, Webster KE, et al. Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J Exp Med 2004;200: 1015-26.
-
(2004)
J Exp Med
, vol.200
, pp. 1015-1026
-
-
Liston, A.1
Gray, D.H.2
Lesage, S.3
Fletcher, A.L.4
Wilson, J.5
Webster, K.E.6
-
43
-
-
13544262691
-
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
-
Kuroda N, Mitani T, Takeda N, Ishimaru N, Arakaki R, Hayashi Y, et al. Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol 2005;174:1862-70.
-
(2005)
J Immunol
, vol.174
, pp. 1862-1870
-
-
Kuroda, N.1
Mitani, T.2
Takeda, N.3
Ishimaru, N.4
Arakaki, R.5
Hayashi, Y.6
-
44
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan YY, Flavell RA. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007;445: 766-70.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
45
-
-
0036812718
-
Antigens derived from melanocyte differentiation proteins: Self-tolerance, autoimmunity, and use for cancer immunotherapy
-
Engelhard VH, Bullock TN, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy. Immunol Rev 2002;188:136-46.
-
(2002)
Immunol Rev
, vol.188
, pp. 136-146
-
-
Engelhard, V.H.1
Bullock, T.N.2
Colella, T.A.3
Sheasley, S.L.4
Mullins, D.W.5
|