Spatial Pattern Dynamics of 3D Stem Cell Loss of Pluripotency via Rules-Based Computational Modeling

PLoS Computational Biology

Volumn 9, Issue 3, 2013, Pages

  White, Douglas E ^a   Kinney, Melissa A ^a   McDevitt, Todd C ^a   Kemp, Melissa L ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATES; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; PROCESS CONTROL;

CELL-FATE; EMBRYOID BODY; EMBRYONIC STEM CELLS; MULTICELLULAR AGGREGATES; PATTERN DYNAMICS; PLURIPOTENCY; RULE BASED; SPATIAL PATTERNS; STEM CELL DIFFERENTIATION; STEM-CELL;

STEM CELLS;

OCTAMER TRANSCRIPTION FACTOR 4;

ANIMAL CELL; ARTICLE; CALCULATION; CELL AGGREGATION; CELL FATE; CELL INTERACTION; CELL LOSS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; EMBRYOID BODY; IN VITRO STUDY; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MICROENVIRONMENT; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHASE TRANSITION; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIMULATION; SPATIOTEMPORAL ANALYSIS; STEM CELL NICHE; STRUCTURE ANALYSIS;

EID: 84875981227     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002952     Document Type: Article

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