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Volumn 366, Issue 1575, 2011, Pages 2238-2246

Mapping the networks for pluripotency

Author keywords

Embryonic stem cell; Mouse embryonic stem cell like interconversion; Pluripotency; Signalling pathways; Transcriptional network

Indexed keywords

HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR;

EID: 79960071635     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2011.0005     Document Type: Article
Times cited : (14)

References (66)
  • 1
    • 33645113300 scopus 로고    scopus 로고
    • From teratocarcinomas to embryonic stem cells and beyond: A history of embryonic stem cell research
    • (doi:10.1038/nrg1827)
    • Solter, D. 2006 From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research. Nat. Rev. Genet. 7, 319-327. (doi:10.1038/nrg1827)
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 319-327
    • Solter, D.1
  • 2
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • (doi:10.1038/292154a0)
    • Evans, M. J. & Kaufman, M. H. 1981 Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156. (doi:10.1038/292154a0)
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 3
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • (doi:10.1073/pnas.78.12.7634)
    • Martin, G. R. 1981 Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl Acad. Sci. USA 78, 7634-7638. (doi:10.1073/pnas.78.12.7634)
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 6
    • 69649084228 scopus 로고    scopus 로고
    • The transcriptional foundation of pluripotency
    • (doi:10.1242/dev.024398)
    • Chambers, I. & Tomlinson, S. R. 2009 The transcriptional foundation of pluripotency. Development 136, 2311-2322. (doi:10.1242/dev.024398)
    • (2009) Development , vol.136 , pp. 2311-2322
    • Chambers, I.1    Tomlinson, S.R.2
  • 7
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • (doi:10.1016/S0092-8674(03)00847-X)
    • Ying, Q. L., Nichols, J., Chambers, I. & Smith, A. 2003 BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115, 281-292. (doi:10.1016/S0092-8674(03)00847-X)
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 10
    • 34447527158 scopus 로고    scopus 로고
    • Derivation of pluripotent epiblast stem cells from mammalian embryos
    • (doi:10.1038/nature05950)
    • Brons, I. G. et al. 2007 Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448, 191-195. (doi:10.1038/nature05950)
    • (2007) Nature , vol.448 , pp. 191-195
    • Brons, I.G.1
  • 11
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • (doi:10.1038/nature05972)
    • Tesar, P. J., Chenoweth, J. G., Brook, F. A., Davies, T. J., Evans, E. P., Mack, D. L., Gardner, R. L. & McKay, R.D. 2007 New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199. (doi:10.1038/nature05972)
    • (2007) Nature , vol.448 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3    Davies, T.J.4    Evans, E.P.5    Mack, D.L.6    Gardner, R.L.7    McKay, R.D.8
  • 12
    • 16244400050 scopus 로고    scopus 로고
    • TGFb/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • (doi:10.1242/dev.01706)
    • James, D., Levine, A. J., Besser, D. & Hemmati-Brivanlou, A. 2005 TGFb/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132, 1273-1282. (doi:10.1242/dev.01706)
    • (2005) Development , vol.132 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 13
    • 77956199358 scopus 로고    scopus 로고
    • Stat3 activation is limiting for reprogramming to ground state pluripotency
    • (doi:10.1016/j.stem.2010.06.022)
    • Yang, J., van Oosten, A. L., Theunissen, T. W., Guo, G., Silva, J. C. & Smith, A. 2010 Stat3 activation is limiting for reprogramming to ground state pluripotency. Cell Stem Cell 7, 319-328. (doi:10.1016/j.stem.2010.06.022)
    • (2010) Cell Stem Cell , vol.7 , pp. 319-328
    • Yang, J.1    van Oosten, A.L.2    Theunissen, T.W.3    Guo, G.4    Silva, J.C.5    Smith, A.6
  • 14
    • 66049136895 scopus 로고    scopus 로고
    • Klf4 reverts developmentally programmed restriction of ground state pluripotency
    • (doi:10.1242/dev.030957)
    • Guo, G., Yang, J., Nichols, J., Hall, J. S., Eyres, I., Mansfield, W. & Smith, A. 2009 Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 136, 1063-1069. (doi:10.1242/dev.030957)
    • (2009) Development , vol.136 , pp. 1063-1069
    • Guo, G.1    Yang, J.2    Nichols, J.3    Hall, J.S.4    Eyres, I.5    Mansfield, W.6    Smith, A.7
  • 15
    • 70350627509 scopus 로고    scopus 로고
    • Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
    • (doi:10.1038/nature08534)
    • Bao, S., Tang, F., Li X., Hayashi, K., Gillich, A., Lao, K. & Surani,M.A. 2009 Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461, 1292-1295. (doi:10.1038/nature08534)
    • (2009) Nature , vol.461 , pp. 1292-1295
    • Bao, S.1    Tang, F.2    Li, X.3    Hayashi, K.4    Gillich, A.5    Lao, K.6    Surani, M.A.7
  • 16
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • doi:10.1016/S0092-8674(00)81769-9
    • Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Scholer, H. & Smith, A. 1998 Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391. (doi:10.1016/S0092-8674(00)81769-9)
    • (1998) Cell , vol.95 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5    Chambers, I.6    Scholer, H.7    Smith, A.8
  • 17
    • 68749110887 scopus 로고    scopus 로고
    • Nanog is the gateway to the pluripotent ground state
    • (doi:10.1016/j.cell.2009.07.039)
    • Silva, J. et al. 2009 Nanog is the gateway to the pluripotent ground state. Cell 138, 722-737. (doi:10.1016/j.cell.2009.07.039)
    • (2009) Cell , vol.138 , pp. 722-737
    • Silva, J.1
  • 18
    • 0037227099 scopus 로고    scopus 로고
    • Multipotent cell lineages in early mouse development depend on SOX2 function
    • (doi:10.1101/gad.224503)
    • Avilion, A. A., Nicolis, S. K., Pevny, L. H., Perez, L., Vivian, N. & Lovell-Badge, R. 2003 Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 17, 126-140. (doi:10.1101/gad.224503)
    • (2003) Genes Dev , vol.17 , pp. 126-140
    • Avilion, A.A.1    Nicolis, S.K.2    Pevny, L.H.3    Perez, L.4    Vivian, N.5    Lovell-Badge, R.6
  • 19
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • (doi:10.1016/j.cell.2005.08.020)
    • Boyer, L. A. et al. 2005 Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122, 947-956. (doi:10.1016/j.cell.2005.08.020)
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1
  • 20
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • (doi:10.1038/ng1760)
    • Loh, Y. H. et al. 2006 The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38, 431-440. (doi:10.1038/ng1760)
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1
  • 21
    • 21744444920 scopus 로고    scopus 로고
    • Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells
    • (doi:10.1128/MCB.25.14.6031-6046.2005)
    • Chew, J. L. et al. 2005 Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol. Cell Biol. 25, 6031-6046. (doi:10.1128/MCB.25.14.6031-6046.2005)
    • (2005) Mol Cell Biol , vol.25 , pp. 6031-6046
    • Chew, J.L.1
  • 22
    • 14844359620 scopus 로고    scopus 로고
    • Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression
    • (doi:10.1128/MCB.25.6.2475-2485.2005)
    • Kuroda, T., Tada, M., Kubota, H., Kimura, H., Hatano, S. Y., Suemori, H., Nakatsuji, N. & Tada, T. 2005 Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol. Cell Biol. 25, 2475-2485. (doi:10.1128/MCB.25.6.2475-2485.2005)
    • (2005) Mol Cell Biol , vol.25 , pp. 2475-2485
    • Kuroda, T.1    Tada, M.2    Kubota, H.3    Kimura, H.4    Hatano, S.Y.5    Suemori, H.6    Nakatsuji, N.7    Tada, T.8
  • 23
    • 14044275706 scopus 로고    scopus 로고
    • Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells
    • (doi:10.1074/jbc.M410015200)
    • Okumura-Nakanishi, S., Saito, M., Niwa, H. & Ishikawa, F. 2005 Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J. Biol. Chem. 280, 5307-5317. (doi:10.1074/jbc.M410015200)
    • (2005) J. Biol. Chem , vol.280 , pp. 5307-5317
    • Okumura-Nakanishi, S.1    Saito, M.2    Niwa, H.3    Ishikawa, F.4
  • 24
    • 21644434480 scopus 로고    scopus 로고
    • Transcriptional regulation of nanog by OCT4 and SOX2
    • (doi:10.1074/jbc.M502573200)
    • Rodda, D. J., Chew, J. L., Lim, L. H., Loh, Y. H., Wang, B., Ng, H. H. & Robson, P. 2005 Transcriptional regulation of nanog by OCT4 and SOX2. J. Biol. Chem. 280, 24731-24737. (doi:10.1074/jbc.M502573200)
    • (2005) J. Biol. Chem , vol.280 , pp. 24731-24737
    • Rodda, D.J.1    Chew, J.L.2    Lim, L.H.3    Loh, Y.H.4    Wang, B.5    Ng, H.H.6    Robson, P.7
  • 25
    • 33751092246 scopus 로고    scopus 로고
    • A protein interaction network for pluripotency of embryonic stem cells
    • (doi:10.1038/nature05284)
    • Wang, J., Rao, S., Chu, J., Shen, X., Levasseur, D. N., Theunissen, T. W. & Orkin, S. H. 2006 A protein interaction network for pluripotency of embryonic stem cells. Nature 444, 364-368. (doi:10.1038/nature05284)
    • (2006) Nature , vol.444 , pp. 364-368
    • Wang, J.1    Rao, S.2    Chu, J.3    Shen, X.4    Levasseur, D.N.5    Theunissen, T.W.6    Orkin, S.H.7
  • 27
    • 77949881949 scopus 로고    scopus 로고
    • An expanded Oct4 interaction network: Implications for stem cell biology, development, and disease
    • (doi:10.1016/j.stem.2010.03.004)
    • Pardo, M., Lang, B., Yu, L., Prosser, H., Bradley, A., Babu, M. M. & Choudhary, J. 2010 An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell 6, 382-395. (doi:10.1016/j.stem.2010.03.004)
    • (2010) Cell Stem Cell , vol.6 , pp. 382-395
    • Pardo, M.1    Lang, B.2    Yu, L.3    Prosser, H.4    Bradley, A.5    Babu, M.M.6    Choudhary, J.7
  • 28
    • 44649086468 scopus 로고    scopus 로고
    • Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells
    • (doi:10.1038/ncb1736)
    • Liang, J. et al. 2008 Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat. Cell Biol. 10, 731-739. (doi:10.1038/ncb1736)
    • (2008) Nat Cell Biol , vol.10 , pp. 731-739
    • Liang, J.1
  • 29
    • 65249173999 scopus 로고    scopus 로고
    • An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network
    • (doi:10.1073/pnas.0812888106)
    • Ho, L., Jothi, R., Ronan, J. L., Cui, K., Zhao, K. & Crabtree, G. R. 2009 An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proc. Natl Acad. Sci. USA 106, 5187-5191. (doi:10.1073/pnas.0812888106)
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 5187-5191
    • Ho, L.1    Jothi, R.2    Ronan, J.L.3    Cui, K.4    Zhao, K.5    Crabtree, G.R.6
  • 30
    • 62549095522 scopus 로고    scopus 로고
    • SWI/SNFBrg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells
    • (doi:10.1634/stemcells.2008-0710)
    • Kidder, B. L., Palmer, S. & Knott, J. G. 2009 SWI/SNFBrg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. Stem Cells 27, 317-328. (doi:10.1634/stemcells.2008-0710)
    • (2009) Stem Cells , vol.27 , pp. 317-328
    • Kidder, B.L.1    Palmer, S.2    Knott, J.G.3
  • 32
    • 64349096829 scopus 로고    scopus 로고
    • A genome-wide RNAi screen identifies a new transcriptional module required for selfrenewal
    • (doi:10.1101/gad.1769609)
    • Hu, G., Kim, J., Xu, Q., Leng, Y., Orkin, S. H. & Elledge, S. J. 2009 A genome-wide RNAi screen identifies a new transcriptional module required for selfrenewal. Genes Dev. 23, 837-848. (doi:10.1101/gad.1769609)
    • (2009) Genes Dev , vol.23 , pp. 837-848
    • Hu, G.1    Kim, J.2    Xu, Q.3    Leng, Y.4    Orkin, S.H.5    Elledge, S.J.6
  • 33
    • 65349123354 scopus 로고    scopus 로고
    • A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity
    • (doi:10.1016/j.stem.2009.03.009)
    • Ding, L. et al. 2009 A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 4, 403-415. (doi:10.1016/j.stem.2009.03.009)
    • (2009) Cell Stem Cell , vol.4 , pp. 403-415
    • Ding, L.1
  • 34
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • (doi:10.1016/j.cell.2008.04.043)
    • Chen, X. et al. 2008 Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133, 1106-1117. (doi:10.1016/j.cell.2008.04.043)
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1
  • 35
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • (doi:10.1016/j.cell.2008.02.039)
    • Kim, J., Chu, J., Shen, X., Wang, J. & Orkin, S. H. 2008 An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132, 1049-1061. (doi:10.1016/j.cell.2008.02.039)
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 36
    • 78149465975 scopus 로고    scopus 로고
    • A genome-wide RNAi screen reveals determinants of human ES cell identity
    • (doi:10.1038/nature09531)
    • Chia, N. Y. et al. 2010 A genome-wide RNAi screen reveals determinants of human ES cell identity. Nature 468, 316-320. (doi:10.1038/nature09531)
    • (2010) Nature , vol.468 , pp. 316-320
    • Chia, N.Y.1
  • 37
    • 70450160004 scopus 로고    scopus 로고
    • Systems-level dynamic analyses of fate change in murine embryonic stem cells
    • (doi:10.1038/nature08575)
    • Lu, R. et al. 2009 Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature 462, 358-362. (doi:10.1038/nature08575)
    • (2009) Nature , vol.462 , pp. 358-362
    • Lu, R.1
  • 38
    • 70349325798 scopus 로고    scopus 로고
    • Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
    • (doi:10.1016/j.stem.2009.07.012)
    • Nishiyama, A. et al. 2009 Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5, 420-433. (doi:10.1016/j.stem.2009.07.012)
    • (2009) Cell Stem Cell , vol.5 , pp. 420-433
    • Nishiyama, A.1
  • 39
    • 77954100084 scopus 로고    scopus 로고
    • Transposable elements have rewired the core regulatory network of human embryonic stem cells
    • (doi:10.1038/ng.600)
    • Kunarso, G., Chia, N. Y., Jeyakani, J., Hwang, C., Lu, X., Chan, Y. S., Ng, H. H. & Bourque, G. 2010 Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat. Genet. 42, 631-634. (doi:10.1038/ng.600)
    • (2010) Nat cGenet , vol.42 , pp. 631-634
    • Kunarso, G.1    Chia, N.Y.2    Jeyakani, J.3    Hwang, C.4    Lu, X.5    Chan, Y.S.6    Ng, H.H.7    Bourque, G.8
  • 40
    • 70349865017 scopus 로고    scopus 로고
    • KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells
    • (doi:10.1002/stem.143)
    • Chan, K. K., Zhang, J., Chia, N. Y., Chan, Y. S., Sim, H. S., Tan, K. S., Oh, S. K., Ng, H. H. & Choo, A. B. 2009 KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells. Stem Cells 27, 2114-2125. (doi:10.1002/stem.143)
    • (2009) Stem Cells , vol.27 , pp. 2114-2125
    • Chan, K.K.1    Zhang, J.2    Chia, N.Y.3    Chan, Y.S.4    Sim, H.S.5    Tan, K.S.6    Oh, S.K.7    Ng, H.H.8    Choo, A.B.9
  • 41
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • (doi:10.1101/gad.12.13.2048)
    • Niwa, H., Burdon, T., Chambers, I. & Smith, A. 1998 Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 12, 2048-2060. (doi:10.1101/gad.12.13.2048)
    • (1998) Genes Dev , vol.12 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 42
    • 0033152966 scopus 로고    scopus 로고
    • Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
    • (doi:10.1006/dbio.1999.9265)
    • Burdon, T., Stracey, C., Chambers, I., Nichols, J. & Smith, A. 1999 Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev. Biol. 210, 30-43. (doi:10.1006/dbio.1999.9265)
    • (1999) Dev Biol , vol.210 , pp. 30-43
    • Burdon, T.1    Stracey, C.2    Chambers, I.3    Nichols, J.4    Smith, A.5
  • 43
    • 9144239955 scopus 로고    scopus 로고
    • Regulation of embryonic stem cell selfrenewal by phosphoinositide 3-kinase-dependent signaling
    • (doi:10.1074/jbc.M406467200)
    • Paling, N. R., Wheadon, H., Bone, H. K. & Welham, M. J. 2004 Regulation of embryonic stem cell selfrenewal by phosphoinositide 3-kinase-dependent signaling. J. Biol. Chem. 279, 48063-48070. (doi:10.1074/jbc.M406467200)
    • (2004) J. Biol. Chem , vol.279 , pp. 48063-48070
    • Paling, N.R.1    Wheadon, H.2    Bone, H.K.3    Welham, M.J.4
  • 44
    • 34548587064 scopus 로고    scopus 로고
    • FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
    • (doi:10.1242/dev.02880)
    • Kunath, T., Saba-El-Leil, M. K., Almousailleakh, M., Wray, J., Meloche, S. & Smith, A. 2007 FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 134, 2895-2902. (doi:10.1242/dev.02880)
    • (2007) Development , vol.134 , pp. 2895-2902
    • Kunath, T.1    Saba-El-Leil, M.K.2    Almousailleakh, M.3    Wray, J.4    Meloche, S.5    Smith, A.6
  • 45
    • 0033517123 scopus 로고    scopus 로고
    • STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
    • (doi:10.1093/emboj/18.15.4261)
    • Matsuda, T., Nakamura, T., Nakao, K., Arai, T., Katsuki, M., Heike, T. & Yokota, T. 1999 STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J. 18, 4261-4269. (doi:10.1093/emboj/18.15.4261)
    • (1999) EMBO J , vol.18 , pp. 4261-4269
    • Matsuda, T.1    Nakamura, T.2    Nakao, K.3    Arai, T.4    Katsuki, M.5    Heike, T.6    Yokota, T.7
  • 46
    • 69249107379 scopus 로고    scopus 로고
    • Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog
    • (doi:10.1002/stem.110)
    • Bourillot, P. Y., Aksoy, I., Schreiber, V., Wianny, F., Schulz, H., Hummel, O., Hubner, N. & Savatier, P. 2009 Novel STAT3 target genes exert distinct roles in the inhibition of mesoderm and endoderm differentiation in cooperation with Nanog. Stem Cells 27, 1760-1771. (doi:10.1002/stem.110)
    • (2009) Stem Cells , vol.27 , pp. 1760-1771
    • Bourillot, P.Y.1    Aksoy, I.2    Schreiber, V.3    Wianny, F.4    Schulz, H.5    Hummel, O.6    Hubner, N.7    Savatier, P.8
  • 47
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • (doi:10.1016/S0092-8674(03)00392-1
    • Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S. & Smith, A. 2003 Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655. (doi:10.1016/S0092-8674(03)00392-1)
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 48
    • 70450270857 scopus 로고    scopus 로고
    • Oct4 and LIF/Stat3 additively induce Kruppel factors to sustain embryonic stem cell selfrenewal
    • (doi:10.1016/j.stem.2009.11.003)
    • Hall, J. et al. 2009 Oct4 and LIF/Stat3 additively induce Kruppel factors to sustain embryonic stem cell selfrenewal. Cell Stem Cell 5, 597-609. (doi:10.1016/j.stem.2009.11.003)
    • (2009) Cell Stem Cell , vol.5 , pp. 597-609
    • Hall, J.1
  • 49
    • 67650032868 scopus 로고    scopus 로고
    • A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
    • (doi:10.1038/nature08113)
    • Niwa, H., Ogawa, K., Shimosato, D. & Adachi, K. 2009 A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells. Nature 460, 118-122. (doi:10.1038/nature08113)
    • (2009) Nature , vol.460 , pp. 118-122
    • Niwa, H.1    Ogawa, K.2    Shimosato, D.3    Adachi, K.4
  • 50
    • 77449161605 scopus 로고    scopus 로고
    • Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells
    • (doi:10.1016/j.stem.2010.01.003)
    • Greber, B. et al. 2010 Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell 6, 215-226. (doi:10.1016/j.stem.2010.01.003)
    • (2010) Cell Stem Cell , vol.6 , pp. 215-226
    • Greber, B.1
  • 51
    • 57449090247 scopus 로고    scopus 로고
    • Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity
    • (doi:10.1089/scd.2008.0035)
    • Greber, B., Lehrach, H. & Adjaye, J. 2008 Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity. Stem Cells Dev 17, 1065-1077. (doi:10.1089/scd.2008.0035)
    • (2008) Stem Cells Dev , vol.17 , pp. 1065-1077
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 52
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • (doi:10.1038/sj.onc.1208927)
    • Zavadil, J. & Bottinger, E. P. 2005 TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 24, 5764-5774. (doi:10.1038/sj.onc.1208927)
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 53
    • 77952360137 scopus 로고    scopus 로고
    • Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and selfrenewal by small molecules
    • (doi:10.1073/pnas.1002024107)
    • Xu, Y., Zhu, X., Hahm, H. S., Wei, W., Hao, E., Hayek, A. & Ding, S. 2010 Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and selfrenewal by small molecules. Proc. Natl Acad. Sci. USA 107, 8129-8134. (doi:10.1073/pnas.1002024107)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 8129-8134
    • Xu, Y.1    Zhu, X.2    Hahm, H.S.3    Wei, W.4    Hao, E.5    Hayek, A.6    Ding, S.7
  • 54
    • 66049117813 scopus 로고    scopus 로고
    • Naive and primed pluripotent states
    • (doi:10.1016/j.stem.2009.05.015)
    • Nichols, J. & Smith, A. 2009 Naive and primed pluripotent states. Cell Stem Cell 4, 487-492. (doi:10.1016/j.stem.2009.05.015)
    • (2009) Cell Stem Cell , vol.4 , pp. 487-492
    • Nichols, J.1    Smith, A.2
  • 55
    • 67349183976 scopus 로고    scopus 로고
    • Metastable pluripotent states in NOD-mouse-derived ESCs
    • (doi:10.1016/j.stem.2009.04.015)
    • Hanna, J. et al. 2009 Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell 4, 513-524. (doi:10.1016/j.stem.2009.04.015)
    • (2009) Cell Stem Cell , vol.4 , pp. 513-524
    • Hanna, J.1
  • 56
    • 57649245579 scopus 로고    scopus 로고
    • Germline competent embryonic stem cells derived from rat blastocysts
    • (doi:10.1016/j.cell.2008.12.006)
    • Li, P. et al. 2008 Germline competent embryonic stem cells derived from rat blastocysts. Cell 135, 1299-1310. (doi:10.1016/j.cell.2008.12.006)
    • (2008) Cell , vol.135 , pp. 1299-1310
    • Li, P.1
  • 57
    • 57649181379 scopus 로고    scopus 로고
    • Capture of authentic embryonic stem cells from rat blastocysts
    • (doi:10.1016/j.cell.2008.12.007)
    • Buehr, M. et al. 2008 Capture of authentic embryonic stem cells from rat blastocysts. Cell 135, 1287-1298. (doi:10.1016/j.cell.2008.12.007)
    • (2008) Cell , vol.135 , pp. 1287-1298
    • Buehr, M.1
  • 58
    • 77956524118 scopus 로고    scopus 로고
    • Production of p53 gene knockout rats by homologous recombination in embryonic stem cells
    • (doi:10.1038/nature09368)
    • Tong, C., Li, P., Wu, N. L., Yan, Y. & Ying, Q. L. 2010 Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature 467,211-213. (doi:10.1038/nature09368)
    • (2010) Nature , vol.467 , pp. 211-213
    • Tong, C.1    Li, P.2    Wu, N.L.3    Yan, Y.4    Ying, Q.L.5
  • 60
    • 77956902055 scopus 로고    scopus 로고
    • Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules
    • (doi:10.1074/jbc.c110.150599)
    • Zhou, H. et al. 2010 Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. J. Biol. Chem 285, 29676-29680. (doi:10.1074/jbc.c110.150599)
    • (2010) J. Biol. Chem , vol.285 , pp. 29676-29680
    • Zhou, H.1
  • 61
    • 33745187327 scopus 로고    scopus 로고
    • Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications
    • (doi:10.1016/j.chembiol.2006.05.004)
    • Lee, M. G., Wynder, C., Schmidt, D. M., McCafferty, D. G. & Shiekhattar, R. 2006 Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem. Biol. 13, 563-567. (doi:10.1016/j.chembiol.2006.05.004)
    • (2006) Chem. Biol , vol.13 , pp. 563-567
    • Lee, M.G.1    Wynder, C.2    Schmidt, D.M.3    McCafferty, D.G.4    Shiekhattar, R.5
  • 62
    • 54949141186 scopus 로고    scopus 로고
    • The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells
    • (doi:10.1016/j.cell.2008.08.035)
    • Chou, Y. F., Chen, H. H., Eijpe, M., Yabuuchi, A., Chenoweth, J.G.,Tesar, P., Lu, J.,McKay, R.D.&Geijsen, N. 2008 The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells. Cell 135, 449-461. (doi:10.1016/j.cell.2008.08.035)
    • (2008) Cell , vol.135 , pp. 449-461
    • Chou, Y.F.1    Chen, H.H.2    Eijpe, M.3    Yabuuchi, A.4    Chenoweth, J.G.5    Tesar, P.6    Lu, J.7    McKay, R.D.8    Geijsen, N.9
  • 63
    • 70349865021 scopus 로고    scopus 로고
    • Abrogation of E-cadherinmediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal
    • (doi:10.1002/stem.134)
    • Soncin, F. et al. 2009 Abrogation of E-cadherinmediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells 27, 2069-2080. (doi:10.1002/stem.134)
    • (2009) Stem Cells , vol.27 , pp. 2069-2080
    • Soncin, F.1
  • 64
    • 33947233409 scopus 로고    scopus 로고
    • MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal
    • (doi:10.1111/j.1432-0436.2006.00143.x)
    • Li, J.,Wang, G.,Wang, C., Zhao, Y., Zhang, H., Tan, Z., Song, Z., Ding, M. & Deng, H. 2007 MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal. Differentiation 75, 299-307. (doi:10.1111/j.1432-0436.2006.00143.x)
    • (2007) Differentiation , vol.75 , pp. 299-307
    • Li, J.1    Wang, G.2    Wang, C.3    Zhao, Y.4    Zhang, H.5    Tan, Z.6    Song, Z.7    Ding, M.8    Deng, H.9
  • 65
    • 77952699848 scopus 로고    scopus 로고
    • Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
    • (doi:10.1073/pnas.1004584107)
    • Hanna, J. et al. 2010 Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proc. Natl Acad. Sci. USA 107, 9222-9227. (doi:10.1073/pnas.1004584107)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 9222-9227
    • Hanna, J.1
  • 66
    • 77952732489 scopus 로고    scopus 로고
    • Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
    • (doi:10.1016/j.cell.2010.04.010)
    • Lengner, C. J. et al. 2010 Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141, 872-883. (doi:10.1016/j.cell.2010.04.010)
    • (2010) Cell , vol.141 , pp. 872-883
    • Lengner, C.J.1


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