-
1
-
-
21644440395
-
Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells
-
Achiwa Y, Hasegawa K, Komiya T and Udagawa Y: Ursolic acid induces Bax-dependent apoptosis through the caspase-3 pathway in endometrial cancer SNG-II cells. Oncol Rep 13: 51-57, 2005.
-
(2005)
Oncol Rep
, vol.13
, pp. 51-57
-
-
Achiwa, Y.1
Hasegawa, K.2
Komiya, T.3
Udagawa, Y.4
-
2
-
-
80855124898
-
Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells
-
Kim KH, Seo HS, Choi HS, Choi I, Shin YC and Ko SG: Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells. Arch Pharm Res 34: 1363-1372, 2011.
-
(2011)
Arch Pharm Res
, vol.34
, pp. 1363-1372
-
-
Kim, K.H.1
Seo, H.S.2
Choi, H.S.3
Choi, I.4
Shin, Y.C.5
Ko, S.G.6
-
3
-
-
43449137552
-
Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells
-
Manu KA and Kuttan G: Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-kappaB mediated activation of bcl-2 in B16F-10 melanoma cells. Int Immunopharmacol 8: 974-981, 2008.
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 974-981
-
-
Manu, K.A.1
Kuttan, G.2
-
4
-
-
77956975737
-
Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro
-
Liu JJ, Liu WD, Yang HZ, Zhang Y, Fang ZG, Liu PQ, Lin DJ, Xiao RZ, Hu Y, Wang CZ, Li XD, He Y and Huang RW: Inactivation of PI3k/Akt signaling pathway and activation of caspase-3 are involved in tanshinone I-induced apoptosis in myeloid leukemia cells in vitro. Ann Hematol 89: 1089-1097, 2010.
-
(2010)
Ann Hematol
, vol.89
, pp. 1089-1097
-
-
Liu, J.J.1
Liu, W.D.2
Yang, H.Z.3
Zhang, Y.4
Fang, Z.G.5
Liu, P.Q.6
Lin, D.J.7
Xiao, R.Z.8
Hu, Y.9
Wang, C.Z.10
Li, X.D.11
He, Y.12
Huang, R.W.13
-
5
-
-
84863432050
-
Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways
-
Li J, Liang X and Yang X: Ursolic acid inhibits growth and induces apoptosis in gemcitabine-resistant human pancreatic cancer via the JNK and PI3K/Akt/NF-κB pathways. Oncol Rep 28: 501-510, 2012.
-
(2012)
Oncol Rep
, vol.28
, pp. 501-510
-
-
Li, J.1
Liang, X.2
Yang, X.3
-
6
-
-
0042090509
-
Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
-
Shishodia S, Majumdar S, Banerjee S and Aggarwal BB: Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Res 63: 4375-4383, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 4375-4383
-
-
Shishodia, S.1
Majumdar, S.2
Banerjee, S.3
Aggarwal, B.B.4
-
7
-
-
63449089496
-
Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis
-
Tang C, Lu YH, Xie JH, Wang F, Zou JN, Yang JS, Xing YY and Xi T: Downregulation of survivin and activation of caspase-3 through the PI3K/Akt pathway in ursolic acid-induced HepG2 cell apoptosis. Anticancer Drugs 20: 249-258, 2009.
-
(2009)
Anticancer Drugs
, vol.20
, pp. 249-258
-
-
Tang, C.1
Lu, Y.H.2
Xie, J.H.3
Wang, F.4
Zou, J.N.5
Yang, J.S.6
Xing, Y.Y.7
Xi, T.8
-
8
-
-
84862846116
-
Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway
-
Wu B, Wang X, Chi ZF, Hu R, Zhang R, Yang W and Liu ZG: Ursolic acid-induced apoptosis in K562 cells involving upregulation of PTEN gene expression and inactivation of the PI3K/Akt pathway. Arch Pharm Res 35: 543-548, 2012.
-
(2012)
Arch Pharm Res
, vol.35
, pp. 543-548
-
-
Wu, B.1
Wang, X.2
Chi, Z.F.3
Hu, R.4
Zhang, R.5
Yang, W.6
Liu, Z.G.7
-
9
-
-
84864005483
-
Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway
-
Wang J, Li Y, Wang X and Jiang C: Ursolic acid inhibits proliferation and induces apoptosis in human glioblastoma cell lines U251 by suppressing TGF-β1/miR-21/PDCD4 pathway. Basic Clin Pharmacol Toxicol 111: 106-112, 2012.
-
(2012)
Basic Clin Pharmacol Toxicol
, vol.111
, pp. 106-112
-
-
Wang, J.1
Li, Y.2
Wang, X.3
Jiang, C.4
-
10
-
-
84863463970
-
Ursolic acid induces apoptosis by suppressing the expression of FoxM1 in MCF-7 human breast cancer cells
-
Wang JS, Ren TN and Xi T: Ursolic acid induces apoptosis by suppressing the expression of FoxM1 in MCF-7 human breast cancer cells. Med Oncol 29: 10-15, 2012.
-
(2012)
Med Oncol
, vol.29
, pp. 10-15
-
-
Wang, J.S.1
Ren, T.N.2
Xi, T.3
-
11
-
-
34249067695
-
Manoussakis M and Moutsatsou P: Ursolic acid, a naturally occurring triterpenoid, demonstrates anticancer activity on human prostate cancer cells
-
Kassi E, Papoutsi Z, Pratsinis H, Aligiannis N, Manoussakis M and Moutsatsou P: Ursolic acid, a naturally occurring triterpenoid, demonstrates anticancer activity on human prostate cancer cells. J Cancer Res Clin Oncol 133: 493-500, 2007.
-
(2007)
J Cancer Res Clin Oncol
, vol.133
, pp. 493-500
-
-
Kassi, E.1
Papoutsi, Z.2
Pratsinis, H.3
Aligiannis, N.4
-
12
-
-
77951660302
-
Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro
-
Zhang Y, Kong C, Zeng Y, Wang L, Li Z, Wang H, Xu C and Sun Y: Ursolic acid induces PC-3 cell apoptosis via activation of JNK and inhibition of Akt pathways in vitro. Mol Carcinog 49: 374-385, 2010.
-
(2010)
Mol Carcinog
, vol.49
, pp. 374-385
-
-
Zhang, Y.1
Kong, C.2
Zeng, Y.3
Wang, L.4
Li, Z.5
Wang, H.6
Xu, C.7
Sun, Y.8
-
13
-
-
79960009770
-
Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice
-
(Berl)
-
Shanmugam MK, Rajendran P, Li F, Nema T, Vali S, Abbasi T, Kapoor S, Sharma A, Kumar AP, Ho PC, Hui KM and Sethi G: Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice. J Mol Med (Berl) 89: 713-727, 2011.
-
(2011)
J Mol Med
, vol.89
, pp. 713-727
-
-
Shanmugam, M.K.1
Rajendran, P.2
Li, F.3
Nema, T.4
Vali, S.5
Abbasi, T.6
Kapoor, S.7
Sharma, A.8
Kumar, A.P.9
Ho, P.C.10
Hui, K.M.11
Sethi, G.12
-
14
-
-
84862839832
-
The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells
-
Limami Y, Pinon A, Leger DY, Pinault E, Delage C, Beneytout JL, Simon A and Liagre B: The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells. Biochimie 94: 1754-1763, 2012.
-
(2012)
Biochimie
, vol.94
, pp. 1754-1763
-
-
Limami, Y.1
Pinon, A.2
Leger, D.Y.3
Pinault, E.4
Delage, C.5
Beneytout, J.L.6
Simon, A.7
Liagre, B.8
-
15
-
-
71749115319
-
Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species
-
Tu HY, Huang AM, Wei BL, Gan KH, Hour TC, Yang SC, Pu YS and Lin CN: Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species. Bioorg Med Chem 17: 7265-7274, 2009.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 7265-7274
-
-
Tu, H.Y.1
Huang, A.M.2
Wei, B.L.3
Gan, K.H.4
Hour, T.C.5
Yang, S.C.6
Pu, Y.S.7
Lin, C.N.8
-
16
-
-
84862777956
-
Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells
-
Zheng QY, Jin FS, Yao C, Zhang T, Zhang GH and Ai X: Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells. Biochem Biophys Res Commun 419: 741-747, 2012.
-
(2012)
Biochem Biophys Res Commun
, vol.419
, pp. 741-747
-
-
Zheng, Q.Y.1
Jin, F.S.2
Yao, C.3
Zhang, T.4
Zhang, G.H.5
Ai, X.6
-
17
-
-
79959758262
-
Activation of the PI3K/Akt/mTOR pathway correlates with tumour progression and reduced survival in patients with urothelial carcinoma of the urinary bladder
-
Sun CH, Chang YH and Pan CC: Activation of the PI3K/Akt/mTOR pathway correlates with tumour progression and reduced survival in patients with urothelial carcinoma of the urinary bladder. Histopathology 58: 1054-1063, 2011.
-
(2011)
Histopathology
, vol.58
, pp. 1054-1063
-
-
Sun, C.H.1
Chang, Y.H.2
Pan, C.C.3
-
18
-
-
83255185628
-
The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL
-
Plissonnier ML, Fauconnet S, Bittard H and Lascombe I: The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL. PLoS One 6: e28354, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Plissonnier, M.L.1
Fauconnet, S.2
Bittard, H.3
Lascombe, I.4
-
19
-
-
84855733505
-
Methanol extract of Hydroclathrus clathratus suppresses matrix metalloproteinase-9 in T24 bladder carcinoma cells by suppressing the NF-κB and MAPK pathways
-
Jayasooriya RG, Choi YH, Moon SK, Kim WJ and Kim GY: Methanol extract of Hydroclathrus clathratus suppresses matrix metalloproteinase-9 in T24 bladder carcinoma cells by suppressing the NF-κB and MAPK pathways. Oncol Rep 27: 541-546, 2012.
-
(2012)
Oncol Rep
, vol.27
, pp. 541-546
-
-
Jayasooriya, R.G.1
Choi, Y.H.2
Moon, S.K.3
Kim, W.J.4
Kim, G.Y.5
-
20
-
-
84866484345
-
Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells
-
Jul 6, (Epub ahead of print). doi: 10.3892/ijo.2012.1549).
-
Kunze D, Kraemer K, Erdmann K, Froehner M, Wirth MP and Fuessel S: Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells. Int J Oncol: Jul 6, 2012 (Epub ahead of print). doi: 10.3892/ijo.2012.1549).
-
(2012)
Int J Oncol
-
-
Kunze, D.1
Kraemer, K.2
Erdmann, K.3
Froehner, M.4
Wirth, M.P.5
Fuessel, S.6
-
21
-
-
84863354167
-
Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line
-
Chen CC, Cheng YY, Chen SC, Tuan YF, Chen YJ, Chen CY and Chen LC: Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line. Chem Res Toxicol 25: 695-705, 2012.
-
(2012)
Chem Res Toxicol
, vol.25
, pp. 695-705
-
-
Chen, C.C.1
Cheng, Y.Y.2
Chen, S.C.3
Tuan, Y.F.4
Chen, Y.J.5
Chen, C.Y.6
Chen, L.C.7
-
22
-
-
84865025621
-
Norcantharidin triggers cell death and DNA damage through S-phase arrest and ROS-modulated apoptotic pathways in TSGH 8301 human urinary bladder carcinoma cells
-
Yu CC, Ko FY, Yu CS, Lin CC, Huang YP, Yang JS, Lin JP and Chung JG: Norcantharidin triggers cell death and DNA damage through S-phase arrest and ROS-modulated apoptotic pathways in TSGH 8301 human urinary bladder carcinoma cells. Int J Oncol 41: 1050-1060, 2012.
-
(2012)
Int J Oncol
, vol.41
, pp. 1050-1060
-
-
Yu, C.C.1
Ko, F.Y.2
Yu, C.S.3
Lin, C.C.4
Huang, Y.P.5
Yang, J.S.6
Lin, J.P.7
Chung, J.G.8
-
23
-
-
84862697481
-
Interleukin-28A triggers wound healing migration of bladder cancer cells via NF-κB-mediated MMP-9 expression inducing the MAPK pathway
-
Lee SJ, Lim JH, Choi YH, Kim WJ and Moon SK: Interleukin-28A triggers wound healing migration of bladder cancer cells via NF-κB-mediated MMP-9 expression inducing the MAPK pathway. Cell Signal 24: 1734-1742, 2012.
-
(2012)
Cell Signal
, vol.24
, pp. 1734-1742
-
-
Lee, S.J.1
Lim, J.H.2
Choi, Y.H.3
Kim, W.J.4
Moon, S.K.5
-
24
-
-
84860279279
-
Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation
-
Takeuchi A, Eto M, Shiota M, Tatsugami K, Yokomizo A, Kuroiwa K, Itsumi M and Naito S: Sunitinib enhances antitumor effects against chemotherapy- resistant bladder cancer through suppression of ERK1/2 phosphorylation. Int J Oncol 40: 1691-1696, 2012.
-
(2012)
Int J Oncol
, vol.40
, pp. 1691-1696
-
-
Takeuchi, A.1
Eto, M.2
Shiota, M.3
Tatsugami, K.4
Yokomizo, A.5
Kuroiwa, K.6
Itsumi, M.7
Naito, S.8
-
25
-
-
84862797137
-
Bufalin induces G(0)/G(1) phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells
-
Huang WW, Yang JS, Pai SJ, Wu PP, Chang SJ, Chueh FS, Fan MJ, Chiou SM, Kuo HM, Yeh CC, Chen PY, Tsuzuki M and Chung JG: Bufalin induces G(0)/G(1) phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells. Mutat Res 732: 26-33, 2012.
-
(2012)
Mutat Res
, vol.732
, pp. 26-33
-
-
Huang, W.W.1
Yang, J.S.2
Pai, S.J.3
Wu, P.P.4
Chang, S.J.5
Chueh, F.S.6
Fan, M.J.7
Chiou, S.M.8
Kuo, H.M.9
Yeh, C.C.10
Chen, P.Y.11
Tsuzuki, M.12
Chung, J.G.13
-
26
-
-
79961073150
-
Inhibition of cytohesin-1 by siRNA leads to reduced IGFR signaling in prostate cancer
-
Weizhong Z, Shuohui G, Hanjiao Q, Yuhong M, Xiaohua Y, Jian C and Lisen L: Inhibition of cytohesin-1 by siRNA leads to reduced IGFR signaling in prostate cancer. Braz J Med Biol Res 44: 642-646, 2011.
-
(2011)
Braz J Med Biol Res
, vol.44
, pp. 642-646
-
-
Weizhong, Z.1
Shuohui, G.2
Hanjiao, Q.3
Yuhong, M.4
Xiaohua, Y.5
Jian, C.6
Lisen, L.7
-
27
-
-
0033596127
-
Control of apoptosis by Rel/NF-κB transcription factors
-
Barkett M and Gilmore TD: Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 18: 6910-6924, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
28
-
-
0035930326
-
Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis
-
Tang G, Yang J, Minemoto Y and Lin A: Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis. Mol Cell 8: 1005-1016, 2001.
-
(2001)
Mol Cell
, vol.8
, pp. 1005-1016
-
-
Tang, G.1
Yang, J.2
Minemoto, Y.3
Lin, A.4
-
29
-
-
0032532070
-
P53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300
-
Ravi R, Mookerjee B, van Hensbergen Y, Bedi GC, Giordano A, El-Deiry WS, Fuchs EJ and Bedi A: p53-mediated repression of nuclear factor-kappaB RelA via the transcriptional integrator p300. Cancer Res 58: 4531-4536, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 4531-4536
-
-
Ravi, R.1
Mookerjee, B.2
Van Hensbergen, Y.3
Bedi, G.C.4
Giordano, A.5
El-Deiry, W.S.6
Fuchs, E.J.7
Bedi, A.8
|