Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells

Archives of Pharmacal Research

Volumn 34, Issue 8, 2011, Pages 1363-1372

  Kim, Kyung Hun ^a   Seo, Hye Sook ^a   Choi, Han Seok ^a   Choi, In Hwa ^a   Shin, Yong Cheol ^a   Ko, Seong Gyu ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Bax; Bcl 2; Caspases; Fas; Ursolic acid

Indexed keywords

CASPASE 3; CASPASE 8; CYTOCHROME C; DEATH RECEPTOR; FAS RECEPTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG; URSOLIC ACID;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN MDA MB 231; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROMES C; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; TRITERPENES; UP-REGULATION;

EID: 80855124898     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-011-0817-5     Document Type: Article

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