Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 20, 2009, Pages 7265-7274

  Tu, Huang Yao ^a   Huang, A Mei ^b   Wei, Bai Luh ^c   Gan, Kim Hong ^a   Hour, Tzyh Chyuan ^b   Yang, Shyh Chyun ^a   Pu, Yeong Shiau ^d   Lin, Chun Nan ^a,c  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAITUNG UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Anticancer; Cell cycle; Cytotoxicity; NTUB1; ROS; SAR; Seco compound; Synthesis; Ursolic acid derivatives

Indexed keywords

ISOPROPYL 3BETA HYDROXYURS 12 EN 28 OATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; URSOLIC ACID; URSOLIC ACID DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; REACTIVE OXYGEN SPECIES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, INFRARED; TRITERPENES;

EID: 71749115319     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.08.046     Document Type: Article

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