Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line

Chemical Research in Toxicology

Volumn 25, Issue 3, 2012, Pages 695-705

  Chen, Chien Cheng ^a   Cheng, Yu Yang ^a   Chen, Ssu Ching ^b   Tuan, Yen Fan ^a   Chen, Yun Ju ^c   Chen, Chien Yen ^d   Chen, Lei Chin ^c  

^a NATIONAL KAOHSIUNG NORMAL UNIVERSITY   (Taiwan)

^b NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 AMINOBIPHENYL; AMINOBIPHENYL DERIVATIVE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOCYNIN; CYCLOOXYGENASE 2; DIPHENYLIODONIUM SALT; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C JUN; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUTANT; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPERMATOZOON MIDPIECE; TRANSCRIPTION REGULATION; UPREGULATION;

AMINOBIPHENYL COMPOUNDS; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HAIR DYES; HUMANS; MAP KINASE SIGNALING SYSTEM; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; TOBACCO SMOKE POLLUTION; UP-REGULATION; URINARY BLADDER NEOPLASMS;

EID: 84863354167     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx2004689     Document Type: Article

References (44)

1. Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., and Forman, D. (2011) Global cancer statistics. CA Cancer J. Clin. 61, 69-90.
2. Mitra, A. P., Datar, R. H., and Cote, R. J. (2006) Molecular pathways in invasive bladder cancer: New insights into mechanisms, progression, and target identification. J. Clin. Oncol. 24, 5552-5564. (Pubitemid 46631336)
3. Eissa, S., Swellam, M., Labib, R. A., El-Zayat, T., and El Ahmady, O. (2009) A panel of angiogenic factors for early bladder cancer detection: Enzyme immunoassay and Western blot. J. Urol. 181, 1353-1360.
4. Wadhwa, P., Goswami, A. K., Joshi, K., and Sharma, S. K. (2005) Cyclooxygenase-2 expression increases with the stage and grade in transitional cell carcinoma of the urinary bladder. Int. Urol. Nephrol. 37, 47-53. (Pubitemid 41236242)
5. Rizzo, M. T. (2011) Cyclooxygenase-2 in oncogenesis. Clin. Chim. Acta 412, 671-687.
6. Shirahama, T., Arima, J., Akiba, S., and Sakakura, C. (2001) Relation between cyclooxygenase-2 expression and tumor invasiveness and patient survival in transitional cell carcinoma of the urinary bladder. Cancer 92, 188-193. (Pubitemid 32623056)
7. Dhawan, D., Craig, B. A., Cheng, L., Snyder, P. W., Mohammed, S. I., Stewart, J. C., Zheng, R., Loman, R. A., Foster, R. S., and Knapp, D. W. (2010) Effects of short-term celecoxib treatment in patients with invasive transitional cell carcinoma of the urinary bladder. Mol. Cancer Ther. 9, 1371-1377.
8. Baan, R., Straif, K., Grosse, Y., Secretan, B., El Ghissassi, F., Bouvard, V., Benbrahim-Tallaa, L., and Cogliano, V. (2008) Carcinogenicity of some aromatic amines, organic dyes, and related exposures. Lancet Oncol. 9, 322-323.
9. Harling, M., Schablon, A., Schedlbauer, G., Dulon, M., and Nienhaus, A. (2010) Bladder cancer among hairdressers: A meta-analysis. Occup. Environ. Med. 67, 351-358.
10. Turesky, R. J., Freeman, J. P., Holland, R. D., Nestorick, D. M., Miller, D. W., Ratnasinghe, D. L., and Kadlubar, F. F. (2003) Identification of aminobiphenyl derivatives in commercial hair dyes. Chem. Res. Toxicol. 16, 1162-1173. (Pubitemid 37163223)
11. Luceri, F., Pieraccini, G., Moneti, G., and Dolara, P. (1993) Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air. Toxicol. Ind. Health 9, 405-413. (Pubitemid 23191584)
12. Wang, S. C., Chung, J. G., Chen, C. H., and Chen, S. C. (2006) 2- and 4-Aminobiphenyls induce oxidative DNA damage in human hepatoma (Hep G2) cells via different mechanisms. Mutat. Res. 593, 9-21. (Pubitemid 43113358)
13. Abdo, K. M., Murthy, A. S., Haseman, J. K., Dieter, M. P., Hildebrandt, P., and Huff, J. E. (1982) Carcinogenesis bioassay in rats and mice fed diets containing 2-biphenylamine hydrochloride. Fundam. Appl. Toxicol. 2, 201-210. (Pubitemid 13096034)
14. O'Connor, P. M., Lapointe, T. K., Beck, P. L., and Buret, A. G. (2010) Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease. Inflamm. Bowel Dis. 16, 1411-1420.
15. Ozkan, A., and Fiskin, K. (2006) Protective effect of antioxidant enzymes against drug cytotoxicity in MCF-7 cells. Exp. Oncol. 28, 86-88.
16. Yang, M. Y., Lau, S. S., and Monks, T. J. (2005) 2,3,5-tris- (Glutathion-S-yl)hydroquinone (TGHQ)-mediated apoptosis of human promyelocytic leukemia cells is preceded by mitochondrial cytochrome c release in the absence of a decrease in the mitochondrial membrane potential. Toxicol. Sci. 86, 92-100. (Pubitemid 41511354)
17. Makena, P. S., and Chung, K.-T. (2007) Evidence that 4-aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species. Environ. Mol. Mutagen. 48, 404-413. (Pubitemid 47011770)
18. Kim, E. H., Na, H. K., Kim, D. H., Park, S. A., Kim, H. N., Song, N. Y., and Surh, Y. J. (2008) 15-Deoxy-Δ12,14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: A potential role of ROS. Carcinogenesis 29, 688-695.
19. Leto, T. L., Morand, S., Hurt, D., and Ueyama, T. (2009) Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. Antioxid. Redox Signal. 11, 2607-2619.
20. Edderkaoui, M., Nitsche, C., Zheng, L., Pandol, S. J., Gukovsky, I., and Gukovskaya, A. S. (2011) NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox. J. Biol. Chem. 286, 7779-7787.
21. Sumimoto, H. (2008) Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS J. 275, 3249-3277.
22. Bedard, K., and Krause, K.-H. (2007) The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol. Rev. 87, 245-313. (Pubitemid 46209993)
23. Kitz, K., Windischhofer, W., Leis, H. J., Huber, E., Kollroser, M., and Malle, E. (2011) 15-Deoxy-[Delta]12,14-prostaglandin J2 induces Cox-2 expression in human osteosarcoma cells through MAPK and EGFR activation involving reactive oxygen species. Free Radical Biol. Med. 50, 854-865.
24. Chen, L. C., Chen, B. K., Chang, J. M., and Chang, W. C. (2004) Essential role of c-Jun induction and coactivator p300 in epidermal growth factor-induced gene expression of cyclooxygenase-2 in human epidermoid carcinoma A431 cells. Biophys. Biochem. Acta 1683, 38-48.
25. Guo, Y. S., Hellmich, M. R., Wen, X. D., and Townsend, C. M. (2001) Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in Intestinal epithelial cells. J. Biol. Chem. 276, 22941-22947.
26. Chen, B.-K., and Chang, W.-C. (2000) Functional interaction between c-Jun and promoter factor Sp1 in epidermal growth factor-induced gene expression of human 12(S)-lipoxygenase. Proc. Natl. Acad. Sci. U.S.A. 97, 10406-10411.
27. Ghosh, N., Chaki, R., Mandal, V., and Mandal, S. C. (2010) COX-2 as a target for cancer chemotherapy. Pharmacol. Rep. 62, 233-244.
28. Lin, W. N., Lin, C. C., Cheng, H. Y., and Yang, C. M. (2011) Regulation of COX-2 and cPLA2 gene expression by LPS through the RNA-binding protein HuR: Involvement of NADPH oxidase, ROS and MAPKs. Br. J. Pharmacol. 163, 1691-1706.
29. Xie, W., and Herschman, H. R. (1996) Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J. Biol. Chem. 271, 31742-31748. (Pubitemid 26408642)
30. Guan, Z., Buckman, S. Y., Miller, B. W., Springer, L. D., and Morrison, A. R. (1998) Interleukin-1β-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cells. J. Biol. Chem. 273, 28670-28676. (Pubitemid 28507552)
31. Yang, T., Huang, Y., Heasley, L. E., Berl, T., Schnermann, J. B., and Briggs, J. P. (2000) MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells. J. Biol. Chem. 275, 23281-23286. (Pubitemid 30646228)
32. Reddy, K. B., Nabha, S. M., and Atanaskova, N. (2003) Role of MAP kinase in tumor progression and invasion. Cancer Metastasis Rev. 22, 395-403. (Pubitemid 36791895)
33. Paik, J., Lee, J. Y., and Hwang, D. (2002) Signaling pathways for TNFα-induced COX-2 expression: Mediation through MAP kinases and NFκB, and inhibition by certain nonsteroidal anti-inflammatory drugs. Adv. Exp. Med. Biol. 507, 503-508. (Pubitemid 37330227)
34. Chang, Y. J., Wu, M. S., Lin, J. T., and Chen, C. C. (2005) Helicobacter pylori-induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase-2 induction through TLR2/TLR9 and promoter regulation. J. Immunol. 175, 8242-8252.
35. Huang, W. C., Chai, C. Y., Chen, W. C., Hou, M. F., Wang, Y. S., Chiu, Y. C., Lu, S. R., Chang, W. C., Juo, S. H. H., Wang, J. Y., and Chang, W. C. (2011) Histamine regulates cyclooxygenase 2 gene activation through Orai1-mediated NFκB activation in lung cancer cells. Cell Calcium 50, 27-35.
36. Wang, Y.-N., Chen, Y.-J., and Chang, W.-C. (2006) Activation of extracellular signal-regulated kinase signaling by epidermal growth factor mediates c-Jun activation and p300 recruitment in keratin 16 gene expression. Mol. Pharmacol. 69, 85-98. (Pubitemid 43048896)
37. Livingstone, C., Patel, G., and Jones, N. (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14, 1785-1797.
38. Lu, D. Y., Leung, Y. M., Huang, S. M., and Wong, K. L. (2010) Bradykinin-induced cell migration and COX-2 production mediated by the bradykinin B1 receptor in glioma cells. J. Cell. Biochem. 110, 141-150.
39. Looby, E., Abdel-Latif, M. M., Athie-Morales, V., Duggan, S., Long, A., and Kelleher, D. (2009) Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. BMC Cancer 9, 190.
40. Zhang, D., Li, J., Song, L., Ouyang, W., Gao, J., and Huang, C. (2008) A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol- 13-acetate-induced cell transformation through regulating cell cycle progression. Mol. Cancer Res. 6, 165-174. (Pubitemid 351378176)
41. Halliwell, B. (2007) Oxidative stress and cancer: Have we moved forward? Biochem. J. 401, 1-11.
42. Parinandi, N. L., Kleinberg, M. A., Usatyuk, P. V., Cummings, R. J., Pennathur, A., Cardounel, A. J., Zweier, J. L., Garcia, J. G. N., and Natarajan, V. (2003) Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 284, L26-L38. (Pubitemid 35471255)
43. Zhang, D. X., and Gutterman, D. D. (2007) Mitochondrial reactive oxygen species-mediated signaling in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 292, H2023-2031. (Pubitemid 47084583)
44. Block, K., Gorin, Y., New, D. D., Eid, A., Chelmicki, T., Reed, A., Choudhury, G. G., Parekh, D. J., and Abboud, H. E. (2010) The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin. Am. J. Pathol. 176, 2447-2455.