Conservation of dishevelled structure and function between flies and mice: Isolation and characterization of Dvl2

Mechanisms of Development

Volumn 58, Issue 1-2, 1996, Pages 15-26

  Klingensmith, J ^a   Yang, Y ^b   Axelrod, J D ^c   Beier, D R ^d   Perrimon, N ^c   Sussman, D J ^b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Dishevelled; Drosophila; Dvl2; Mouse

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CHROMOSOME 11; DROSOPHILA; EMBRYO DEVELOPMENT; GENE; GENE ISOLATION; GENE STRUCTURE; IMAGINAL DISC; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030219387     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(96)00549-7     Document Type: Article

References (64)

1. Ausubel, F.M., Brent, R.E., Kingston, R.E., Moore, D.D., Siedman, J.G., Smith, J.A. and Struhl, K. (1987) Current Protocols in Molecular Biology, Wiley Interscience, New York.
2. Beier, D.R., Dushkin, H. and Sussraan, D.J. (1992) Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses. Proc. Natl. Acad. Sci. USA 89, 9102-9106.
3. Bryant, P.J., Watson, K,L., Justice, R. and Woods, D. (1993) Tumor suppressor genes encoding proteins required for cell interactions and signal transduction in Drosophila. Development (suppl.), 239-249.
4. Chakabarti, A., Matthew, G., Colman, A. and Dale, L. (1992) Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos. Development 115, 355-369.
5. Chirgwin, J.M., Przybyla, A.E., MacDonald, R.J. and Rutter, W.J. (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299.
6. Cho, K.-O., Hunt, C.A. and Kennedy, M.B. (1992) The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942.
7. Chou, T.B. and Perrimon, N. (1992) Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. Genetics 131, 643-653.
8. Conlon, R. and Rossant, J. (1992) Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development 116, 357-368.
9. Cui, Y., Brown, J.D., Moon, R.T. and Christian, J.L. (1995) Xwnt8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsalventral axis. Development 121, 2177-2186
10. DeMarais, A.A. and Moon, R.T. (1992) The armadillo homologs β-catenin and plakoglobin are differentially expressed during early development of Xenopus laevis. Dev. Biol. 153, 337-346.
11. Devereux, J., Haebreli, M. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12, 387-395.
12. Dominguez, I., Itoh, K. and Sokol, S.Y. (1995) Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos. PNAS 92, 8498-8502.
13. Driever, W., Siegel, V. and Nusslein-Volhard, C. (1990) Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen, Development 109, 811-820.
14. Gergen, P. and Wieschaus, E.H. (1986) Localized requirements for gene activity in segmentation of Drosophila embryos: analysis of armadillo, fused, giant and unpaired mutations in mosaic embryos. Roux's Arch. Dev. Biol. 195, 49-62.
15. Golic, K.G. and Lindquist, S. (1989) The FLP recombinase of yeast catalyzes site specific recombination in the Drosophila genome. Cell 59, 499-508.
16. Greco, T.L., Sussman, D.J. and Camper, S.A. (1996). Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11. Mamm. Genome, in press.
17. Haegel, H., Larue, L., Ohsugi, M., Federov, L., Herrenknecht, K. and Kemler, R. (1995) Lack of β-catenin affects mouse development at gastrulation. Development 121, 3529-3537.
18. Hanks, M., Wurst, W., Anson-Cartwright, L. Auerbach, A. and Joyner, A. (1995) Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269, 679-682.
19. He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E, and Dawid, I.B. (1995) Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374, 617-622.
20. Heasman, J., Crawford, A., Goldstone, K., Garner-Hamrick, P., Gumbiner, B., McCrea, P., Kintner, C., Yoshida Nora, C. and Wylie, C. (1994) Overexpression of cadherins and underexpression of β-catenin inhibit dorsal mesoderm formation in early Xenopus embryos. Cell 79, 791-803.
21. Huebner, K., Isobe, M., Croce, C.M., Golde, D.W., Kaufman, S.E. and Gasson, J.C. (1985) The human gene encoding GM-CSF is at 5q21-q32, the chromosome region deleted in the 5q-anomaly. Science 230, 1282-1285.
22. Joyner, A.L., Herrup, K., Auerbach, B.A., Davis, C.A. and Rossant, J. (1991) Subtle cerebellar phenotype in mice homozygous for a targeted deletion of the En-2 homeobox. Science 251, 1239-1243.
23. + channels by interaction with a family of membrane-associated guanylate kinases. Nature 378, 85-88.
24. Klingensmith, J. (1993) Genetic Dissection of an Intercellular Signaling Pathway in Drosophila Pattern Formation, Harvard University Press, Cambridge, MA.
25. Klingensmith, J. and Nusse, R. (1994) The wingless signalling system in Drosophila. Dev. Biol. 166, 396-414.
26. Klingensmith, J. and Perrimon, N. (1991) Segment polarity genes and intercellular communication in Drosophila. In Mond, J.J., Cambier, J.C. and Weiss, A. (eds.), Advances in Regulation of Cell Growth, Vol. 2; Cell Activation: Genetic Approaches, Raven Press, New York, 251-274.
27. Klingensmith, J., Nusse, R. and Perrimon, N. (1994) dishevelled encodes a novel protein required for response of target cells to the wingless signal in Drosophila embryos. Genes Dev. 8, 113-130.
28. Kornau, H.-C., Schenker, L.T., Kennedy, M.B. and Seeburg, P.H. (1995) Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269, 1737-1740.
29. Kozak, M. (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44, 283-292.
30. Ku, M. and Melton, D.A. (1993) Xwnt11: a maternally expressed Xenopus wnt gene. Development 119, 1161-1173.
31. Manley, K.F. (1993) A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm. Genome 4, 303-313.
32. McCrea, P., Bieher, W.M. and Gumbiner, B. (1993) Induction of a secondary body axis in Xenopus by antibodies to β-catenin. J. Cell Biol. 123, 477-484.
33. Melton, D.A., Krieg, P.A., Rebagliati, M.R., Maniatis, T., Zinn, K. and Green, M.R. (1984) Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12, 7035-7056.
34. Moon, R.T., Christian, J.L., Campbell, R., McGrew, L.L., DeMarais, A., Torres, M., Lai, C., Olson, D.J. and Kelly, G.M. (1993) Dissecting Wnt signaling pathways and Wnt-sensitive developmental processes through transient misexpression analysis in embryos of Xenopus laevis. Development (suppl.), 85-94.
35. Morris, C., Heisterkamp, N., Hao, Q.L., Testa, J.R., and Groffen, J. (1990) The human tyrosine kinase gene (FER) maps to chromosome 5 and is deleted in myeloid leukemias with a del(5q). Cytogenet. Cell Genet. 53, 196-200.
36. Noordermeer, J., Johnston, P., Rijsewijk, F., Nusse, R. and Lawrence, P. (1992) The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116, 711-719.
37. Noordermeer, J., Klingensmith, J., Perrimon, N. and Nusse, R. (1994) dishevelled and armadillo act in the Wingless signalling pathway in Drosophila, Nature 367, 80-83.
38. Nusse, R. and Varmus, H.E. (1992) Wnt genes. Cell 69, 1073-1087.
39. Parr, B. A. and McMahon, A.P. (1994) Wnt genes and vertebrate development. Curr. Opin. Genet. Dev. 4, 523-528.
40. Parr, B.A. and McMahon, A.P. (1995) Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limbs. Nature 374, 350-353.
41. Perrimon, N. (1994) The genetic basis of patterned baldness in Drosophila. Cell 76, 781-784.
42. Perrimon, N. and Mahowald, A.P. (1987) Multiple functions of the segment polarity genes in Drosophila, Dev. Biol. 119, 587-600.
43. Pierce, S. and Kimelman, D. (1995) Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3. Development 121, 755-765.
44. Ramakrishna, N.R. and Brown, A.M.C. (1993) Wingless, the Drosophila homolog of the proto-oncogene WntI can transform mouse mammary epithelial cells. Development (suppl.), 95-103.
45. Ren, R., Mayer, B.J., Cicchetti, P. and Baltimore, D. (1993) Identification of a ten-amino acid proline-rich SH3 binding site. Science 259, 1157-1161.
46. Riggleman, B., Schedl, P. and Wieschaus, E. (1990) Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell 63, 549-560.
47. Rijsewijk, F., Schuermann, M., Wagenaar, E., Parren, P., Weigel, D. and Nusse, R. (1987) The Drosophila homolog of the mouse mammary oncogene int-I is identical to the segment polarity gene wingless. Cell 50, 649-657.
48. Rogers, S., Wells, R. and Rechsteiner, M. (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234, 364-368.
49. Rothbacher, U., Laurent, M., Blitz, I. Watabe, T., Marsh, J.L. and Cho, K.W.Y. (1995) Functional conservation of the Wnt signaling pathway revealed by ectopic expression of Drosophila dishevelled in Xenopus. Dev. Biol. 170, 717-721.
50. Rowe, L.B., Nadeau, J.H., Turner, R., Frankel, W.N., Letts, V.A., Eppig, J.T., Ko, M.S.H., Thurston, S.J. and Birkenmeir, E.H. (1994) Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm. Genome 5, 253-274.
51. Siegfried, E., Perkins, L.A., Capaci, T.M., and Perrimon, N. (1990) Putative protein kinase product of the Drosophila segment polarity gene zeste-white 3. Nature 345, 825-829.
52. Siegfried, E., Chou, T.B., and Perrimon, N. (1992) Wingless signaling acts through zeste-white 3, the Drosophila homolog of glycagen synthase kinase-3 to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
53. Siegfried, E., Wilder, E.L. and Perrimon, N. (1994) Components of wingless signaling in Drosophila. Nature 367, 76-80.
54. Sokol, S.Y., Christian, J.L., Moon, R.T. and Melton, D.A. (1991) Injected wnt RNA induces a complete body axis in Xenopus embryos. Cell 67, 741-752.
55. Sokol, S.Y., Klingensmith, J., Perrimon, N, and Itoh, K. (1995) Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development 121, 1637-1647.
56. Stark, K., Vainio, S., Vassilvere, G., and McMahon, A.P. (1994) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372, 679-683.
57. Sussman, D., Klingensmith, J., Salinas, P., Nusse, R., and Perrimon, N. (1994) Isolation and characterization of a murine homolog of the Drosophila segment polarity gene dishevelled. Dev. Biol. 166, 73-86.
58. Theisen, H., Purcell, J., Bennett, M., Kansagara, D., Syed, A. and Marsh, J.L. (1994) dishevelled is required during wingless signaling to establish both cell polarity and cell identity. Development 120, 347-360.
59. van den Heuvel, M., Nusse, R., Johnston, P. and Lawrence, P. (1989) Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-749.
60. van den Heuvel, M., Klingensmith, J., Perrimon, N. and Nusse, R. (1993) Cell patterning in the Drosophila embryo: distribution of wingless and engrailed proteins in segment polarity mutants. Development (suppl.), 105-114.
61. Wharton, K.A., Yedvobnick, B., Finnerty, V.G. and Artavanis-Tsakonas, S. (1985) opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in Drosophila melanogaster, Cell 43, 567-581.
62. Wieschaus, E., and Nusslein-Volhard, C.(1986) In Roberts, D.B. (ed.), Looking at Embryos: A Practical Approach. IRL Press, Oxford.
63. Wurst, W., Auerbach, A. and Joyner, A.L. (1994) Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.
64. Yanagawa, S., van Leeuwen, F., Wodarz, A., Klingensmith, J. and Nusse, R. (1995) The Dishevelled protein is modified by Wingless signaling in Drosophila. Genes Dev. 9, 1087-1097.