메뉴 건너뛰기




Volumn 110, Issue 14, 2013, Pages 5606-5611

Preferential eradication of acute myelogenous leukemia stem cells by fenretinide

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CD38 ANTIGEN; FENRETINIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYLCELLULOSE; REACTIVE OXYGEN METABOLITE;

EID: 84875854934     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302352110     Document Type: Article
Times cited : (45)

References (44)
  • 1
    • 23644455476 scopus 로고    scopus 로고
    • Drug therapy for acute myeloid leukemia
    • Tallman MS, Gilliland DG, Rowe JM (2005) Drug therapy for acute myeloid leukemia. Blood 106(4):1154-1163.
    • (2005) Blood , vol.106 , Issue.4 , pp. 1154-1163
    • Tallman, M.S.1    Gilliland, D.G.2    Rowe, J.M.3
  • 2
    • 85047690508 scopus 로고    scopus 로고
    • Opinion: The origin of the cancer stem cell: Current controversies and new insights
    • Bjerkvig R, Tysnes BB, Aboody KS, Najbauer J, Terzis AJ (2005) Opinion: The origin of the cancer stem cell: Current controversies and new insights. Nat Rev Cancer 5(11): 899-904.
    • (2005) Nat Rev Cancer , vol.5 , Issue.11 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.5
  • 3
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414(6859):105-111.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 4
    • 80052468964 scopus 로고    scopus 로고
    • Stem cell gene expression programs influence clinical outcome in human leukemia
    • Eppert K, et al. (2011) Stem cell gene expression programs influence clinical outcome in human leukemia. Nat Med 17(9):1086-1093.
    • (2011) Nat Med , vol.17 , Issue.9 , pp. 1086-1093
    • Eppert, K.1
  • 5
    • 78650444882 scopus 로고    scopus 로고
    • Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia
    • Gentles AJ, Plevritis SK, Majeti R, Alizadeh AA (2010) Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA 304(24):2706-2715.
    • (2010) JAMA , vol.304 , Issue.24 , pp. 2706-2715
    • Gentles, A.J.1    Plevritis, S.K.2    Majeti, R.3    Alizadeh, A.A.4
  • 6
    • 31544436322 scopus 로고    scopus 로고
    • AML engraftment in the NOD/SCID assay reflects the outcome of AML: Implications for our understanding of the heterogeneity of AML
    • Pearce DJ, et al. (2006) AML engraftment in the NOD/SCID assay reflects the outcome of AML: Implications for our understanding of the heterogeneity of AML. Blood 107(3):1166-1173.
    • (2006) Blood , vol.107 , Issue.3 , pp. 1166-1173
    • Pearce, D.J.1
  • 7
    • 25144433295 scopus 로고    scopus 로고
    • High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
    • van Rhenen A, et al. (2005) High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival. Clin Cancer Res 11(18):6520-6527.
    • (2005) Clin Cancer Res , vol.11 , Issue.18 , pp. 6520-6527
    • Van Rhenen, A.1
  • 8
    • 0035886024 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
    • Guzman ML, et al. (2001) Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 98(8):2301-2307.
    • (2001) Blood , vol.98 , Issue.8 , pp. 2301-2307
    • Guzman, M.L.1
  • 9
    • 0035313467 scopus 로고    scopus 로고
    • Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells
    • Guzman ML, et al. (2001) Expression of tumor-suppressor genes interferon regulatory factor 1 and death-associated protein kinase in primitive acute myelogenous leukemia cells. Blood 97(7):2177-2179.
    • (2001) Blood , vol.97 , Issue.7 , pp. 2177-2179
    • Guzman, M.L.1
  • 10
    • 77953005040 scopus 로고    scopus 로고
    • Targeting myeloid leukemia stem cells
    • Jordan CT (2010) Targeting myeloid leukemia stem cells. Sci Transl Med 2(31):31ps21.
    • (2010) Sci Transl Med , vol.2 , Issue.31
    • Jordan, C.T.1
  • 12
    • 77950287628 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML
    • Wang Y, et al. (2010) The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science 327(5973):1650-1653.
    • (2010) Science , vol.327 , Issue.5973 , pp. 1650-1653
    • Wang, Y.1
  • 13
    • 77951040369 scopus 로고    scopus 로고
    • Metabolism and the leukemic stem cell
    • Abdel-Wahab O, Levine RL (2010) Metabolism and the leukemic stem cell. J Exp Med 207(4):677-680.
    • (2010) J Exp Med , vol.207 , Issue.4 , pp. 677-680
    • Abdel-Wahab, O.1    Levine, R.L.2
  • 14
    • 34547660196 scopus 로고    scopus 로고
    • FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system
    • Tothova Z, Gilliland DG (2007) FoxO transcription factors and stem cell homeostasis: Insights from the hematopoietic system. Cell Stem Cell 1(2):140-152.
    • (2007) Cell Stem Cell , vol.1 , Issue.2 , pp. 140-152
    • Tothova, Z.1    Gilliland, D.G.2
  • 15
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham D, Alexandre J, Huang P (2009) Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach? Nat Rev Drug Discov 8(7):579-591.
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.7 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 16
    • 39649085170 scopus 로고    scopus 로고
    • Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl,1,2,4-thiadiazolidine, 3, 5 dione (TDZD-8)
    • Guzman ML, et al. (2007) Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1, 2, 4-thiadiazolidine, 3, 5 dione (TDZD-8). Blood 110(13):4436-4444.
    • (2007) Blood , vol.110 , Issue.13 , pp. 4436-4444
    • Guzman, M.L.1
  • 17
    • 16844363378 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
    • Guzman ML, et al. (2005) The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105(11): 4163-4169.
    • (2005) Blood , vol.105 , Issue.11 , pp. 4163-4169
    • Guzman, M.L.1
  • 18
    • 39649125467 scopus 로고    scopus 로고
    • An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
    • Guzman ML, et al. (2007) An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. Blood 110(13): 4427-4435.
    • (2007) Blood , vol.110 , Issue.13 , pp. 4427-4435
    • Guzman, M.L.1
  • 19
    • 47049105891 scopus 로고    scopus 로고
    • Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data
    • Hassane DC, et al. (2008) Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data. Blood 111(12):5654-5662.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5654-5662
    • Hassane, D.C.1
  • 20
    • 0029816269 scopus 로고    scopus 로고
    • Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl beta-glucuronide
    • Formelli F, Barua AB, Olson JA (1996) Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl beta-glucuronide. FASEB J 10(9):1014-1024.
    • (1996) FASEB J , vol.10 , Issue.9 , pp. 1014-1024
    • Formelli, F.1    Barua, A.B.2    Olson, J.A.3
  • 21
    • 0034662651 scopus 로고    scopus 로고
    • Fenretinide-induced caspase 3 activity involves increased protein stability in a mechanism distinct from reactive oxygen species elevation
    • DiPietrantonio AM, et al. (2000) Fenretinide-induced caspase 3 activity involves increased protein stability in a mechanism distinct from reactive oxygen species elevation. Cancer Res 60(16):4331-4335.
    • (2000) Cancer Res , vol.60 , Issue.16 , pp. 4331-4335
    • Di Pietrantonio, A.M.1
  • 22
    • 0142057512 scopus 로고    scopus 로고
    • N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species
    • Goto H, Takahashi H, Fujii H, Ikuta K, Yokota S (2003) N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species. Int J Hematol 78(3):219-225.
    • (2003) Int J Hematol , vol.78 , Issue.3 , pp. 219-225
    • Goto, H.1    Takahashi, H.2    Fujii, H.3    Ikuta, K.4    Yokota, S.5
  • 23
    • 79651469605 scopus 로고    scopus 로고
    • Preferential involvement of both ROS and ceramide in fenretinide- induced apoptosis of HL60 rather than NB4 and U937 cells
    • Jiang L, et al. (2011) Preferential involvement of both ROS and ceramide in fenretinide- induced apoptosis of HL60 rather than NB4 and U937 cells. Biochem Biophys Res Commun 405(2):314-318.
    • (2011) Biochem Biophys Res Commun , vol.405 , Issue.2 , pp. 314-318
    • Jiang, L.1
  • 24
    • 0030744057 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells
    • Oridate N, et al. (1997) Involvement of reactive oxygen species in N-(4-hydroxyphenyl) retinamide-induced apoptosis in cervical carcinoma cells. J Natl Cancer Inst 89(16): 1191-1198.
    • (1997) J Natl Cancer Inst , vol.89 , Issue.16 , pp. 1191-1198
    • Oridate, N.1
  • 25
    • 0034807456 scopus 로고    scopus 로고
    • Mechanism of fenretinide (4-HPR)- induced cell death
    • Wu JM, DiPietrantonio AM, Hsieh TC (2001) Mechanism of fenretinide (4-HPR)- induced cell death. Apoptosis 6(5):377-388.
    • (2001) Apoptosis , vol.6 , Issue.5 , pp. 377-388
    • Wu, J.M.1    Di Pietrantonio, A.M.2    Hsieh, T.C.3
  • 26
    • 0036842110 scopus 로고    scopus 로고
    • Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells
    • Shimada K, et al. (2002) Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells. Mol Carcinog 35(3):127-137.
    • (2002) Mol Carcinog , vol.35 , Issue.3 , pp. 127-137
    • Shimada, K.1
  • 28
    • 70450241084 scopus 로고    scopus 로고
    • Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer
    • Schneider BJ, et al. (2009) Phase II trial of fenretinide (NSC 374551) in patients with recurrent small cell lung cancer. Invest New Drugs 27(6):571-578.
    • (2009) Invest New Drugs , vol.27 , Issue.6 , pp. 571-578
    • Schneider, B.J.1
  • 29
    • 33745613818 scopus 로고    scopus 로고
    • Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer
    • Veronesi U, et al. (2006) Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer. Ann Oncol 17(7):1065-1071.
    • (2006) Ann Oncol , vol.17 , Issue.7 , pp. 1065-1071
    • Veronesi, U.1
  • 30
    • 0038176443 scopus 로고    scopus 로고
    • Phase i trial and pharmacokinetics of fenretinide in children with neuroblastoma
    • Garaventa A, et al. (2003) Phase I trial and pharmacokinetics of fenretinide in children with neuroblastoma. Clin Cancer Res 9(6):2032-2039.
    • (2003) Clin Cancer Res , vol.9 , Issue.6 , pp. 2032-2039
    • Garaventa, A.1
  • 31
    • 33746799839 scopus 로고    scopus 로고
    • Phase i trial of oral fenretinide in children with high-risk solid tumors: A report from the Children's Oncology Group (CCG 09709)
    • Villablanca JG, et al. (2006) Phase I trial of oral fenretinide in children with high-risk solid tumors: A report from the Children's Oncology Group (CCG 09709). J Clin Oncol 24(21):3423-3430.
    • (2006) J Clin Oncol , vol.24 , Issue.21 , pp. 3423-3430
    • Villablanca, J.G.1
  • 32
    • 14944353655 scopus 로고    scopus 로고
    • Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study
    • Puduvalli VK, et al. (2004) Phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium study. J Clin Oncol 22(21):4282-4289.
    • (2004) J Clin Oncol , vol.22 , Issue.21 , pp. 4282-4289
    • Puduvalli, V.K.1
  • 33
    • 32644449422 scopus 로고    scopus 로고
    • Coordination of intrinsic, extrinsic, and endoplasmic reticulummediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia
    • Du Y, et al. (2006) Coordination of intrinsic, extrinsic, and endoplasmic reticulummediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia. Blood 107(4):1582-1590.
    • (2006) Blood , vol.107 , Issue.4 , pp. 1582-1590
    • Du, Y.1
  • 34
    • 79961238041 scopus 로고    scopus 로고
    • A topology-preserving selection and clustering approach to multidimensional biological data
    • Fang H, et al. (2011) A topology-preserving selection and clustering approach to multidimensional biological data. OMICS 15(7-8):483-494.
    • (2011) OMICS , vol.15 , Issue.7-8 , pp. 483-494
    • Fang, H.1
  • 35
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4(1):44-57.
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 36
    • 70449577142 scopus 로고    scopus 로고
    • Converting redox signaling to apoptotic activities by stress-responsive regulators HSF1 and NRF2 in fenretinide treated cancer cells
    • Wang K, et al. (2009) Converting redox signaling to apoptotic activities by stress-responsive regulators HSF1 and NRF2 in fenretinide treated cancer cells. PLoS One 4(10):e7538.
    • (2009) PLoS One , vol.4 , Issue.10
    • Wang, K.1
  • 37
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, et al. (2003) A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423(6938):409-414.
    • (2003) Nature , vol.423 , Issue.6938 , pp. 409-414
    • Reya, T.1
  • 38
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102(43):15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1
  • 39
    • 11144358111 scopus 로고    scopus 로고
    • Prognostically useful gene-expression profiles in acute myeloid leukemia
    • Valk PJ, et al. (2004) Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med 350(16):1617-1628.
    • (2004) N Engl J Med , vol.350 , Issue.16 , pp. 1617-1628
    • Valk, P.J.1
  • 40
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs
    • Nakanishi C, Toi M (2005) Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 5(4):297-309.
    • (2005) Nat Rev Cancer , vol.5 , Issue.4 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 41
    • 0028006612 scopus 로고
    • Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway
    • Anderson MT, Staal FJ, Gitler C, Herzenberg LA, Herzenberg LA (1994) Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway. Proc Natl Acad Sci USA 91(24):11527-11531.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.24 , pp. 11527-11531
    • Anderson, M.T.1    Staal, F.J.2    Gitler, C.3    Herzenberg, L.A.4    Herzenberg, L.A.5
  • 42
    • 77953715690 scopus 로고    scopus 로고
    • Targeting Wnt signaling: Can we safely eradicate cancer stem cells?
    • Takahashi-Yanaga F, Kahn M (2010) Targeting Wnt signaling: Can we safely eradicate cancer stem cells? Clin Cancer Res 16(12):3153-3162.
    • (2010) Clin Cancer Res , vol.16 , Issue.12 , pp. 3153-3162
    • Takahashi-Yanaga, F.1    Kahn, M.2
  • 43
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • Takebe N, Harris PJ, Warren RQ, Ivy SP (2011) Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 8(2):97-106.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.2 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 44
    • 84860606995 scopus 로고    scopus 로고
    • The significance of low PU.1 expression in patients with acute promyelocytic leukemia
    • Zhu X, et al. (2012) The significance of low PU.1 expression in patients with acute promyelocytic leukemia. J Hematol Oncol 5:22.
    • (2012) J Hematol Oncol , vol.5 , pp. 22
    • Zhu, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.