A single intact ATPase site of the ABC transporter BtuCD drives 5% transport activity yet supports full in vivo vitamin B12 utilization

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 14, 2013, Pages 5434-5439

  Tal, Nir ^a   Ovcharenko, Elena ^a   Lewinson, Oded ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Cooperativity; Membrane permeation; Membrane proteins

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER BTUCD; ADENOSINE TRIPHOSPHATASE; CYANOCOBALAMIN; MALTOSE; MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE MUTATION; HYDROLYSIS; MEMBRANE PERMEABILITY; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL; VITAMIN INTAKE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CATALYTIC DOMAIN; CHROMATOGRAPHY, GEL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROLYSIS; MULTIPROTEIN COMPLEXES; MUTATION; VITAMIN B 12;

ESCHERICHIA COLI;

EID: 84875833653     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209644110     Document Type: Article

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