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Volumn 34, Issue 4, 2012, Pages 743-765

Ceftaroline Fosamil: A Cephalosporin With Activity Against Methicillin-Resistant Staphylococcus Aureus

Author keywords

Ceftaroline; Cephalosporin; Community acquired pneumonia; Methicillin resistant Staphylococcus aureus; Skin and skin structure infections

Indexed keywords

ALANINE AMINOTRANSFERASE; AMIKACIN; ASPARTATE AMINOTRANSFERASE; AVIBACTAM; AZTREONAM; CEFEPIME; CEFTAROLINE FOSAMIL; CEFTRIAXONE; CLOXACILLIN; CREATININE; DAPTOMYCIN; LEVOFLOXACIN; LINEZOLID; MEROPENEM; MOXIFLOXACIN; PLACEBO; TAZOBACTAM; TELAVANCIN; TIGECYCLINE; VANCOMYCIN;

EID: 84859625801     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2012.02.025     Document Type: Review
Times cited : (32)

References (92)
  • 1
    • 2342595765 scopus 로고    scopus 로고
    • Trends in antimicrobial drug development: implications for the future
    • Spellberg B., Powers J.H., Brass E.P., et al. Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 2004, 28:1279-1286.
    • (2004) Clin Infect Dis , vol.28 , pp. 1279-1286
    • Spellberg, B.1    Powers, J.H.2    Brass, E.P.3
  • 2
    • 31044456290 scopus 로고    scopus 로고
    • Changes in the epidemiology of Staphylococcus aureus in intensive care units in US hospitals, 1992-2003
    • Klevens R.M., Edwards J.R., Tenover F.C., et al. Changes in the epidemiology of Staphylococcus aureus in intensive care units in US hospitals, 1992-2003. Clin Infect Dis 2006, 42:389-391.
    • (2006) Clin Infect Dis , vol.42 , pp. 389-391
    • Klevens, R.M.1    Edwards, J.R.2    Tenover, F.C.3
  • 3
    • 19344368919 scopus 로고    scopus 로고
    • Methicillin-resistant Staphylococcus aureus in community-acquired skin infections
    • Moran G.J., Amii R.N., Abrahamian F.M., Talan D.A. Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. Emerg Infect Dis 2005, 11:928-930.
    • (2005) Emerg Infect Dis , vol.11 , pp. 928-930
    • Moran, G.J.1    Amii, R.N.2    Abrahamian, F.M.3    Talan, D.A.4
  • 4
    • 33747343208 scopus 로고    scopus 로고
    • Methicillin-resistant S. aureus infections among patients in the emergency department
    • Moran G.J., Krishnadasan A., Gorwitz R.J., et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med 2006, 355:666-674.
    • (2006) N Engl J Med , vol.355 , pp. 666-674
    • Moran, G.J.1    Krishnadasan, A.2    Gorwitz, R.J.3
  • 5
    • 35349019173 scopus 로고    scopus 로고
    • Invasive methicillin-resistant Staphylococcus aureus infections in the Unites States
    • Klevens R.M., Morrison M.A., Nadle J., et al. Invasive methicillin-resistant Staphylococcus aureus infections in the Unites States. JAMA 2007, 298:1763-1771.
    • (2007) JAMA , vol.298 , pp. 1763-1771
    • Klevens, R.M.1    Morrison, M.A.2    Nadle, J.3
  • 6
    • 58749108809 scopus 로고    scopus 로고
    • Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005
    • Richter S.S., Heilmann K.P., Dohrn C.L., et al. Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005. Clin Infect Dis 2009, 48:e23-e33.
    • (2009) Clin Infect Dis , vol.48
    • Richter, S.S.1    Heilmann, K.P.2    Dohrn, C.L.3
  • 7
    • 66949168809 scopus 로고    scopus 로고
    • Increasing burden of invasive Group B streptococcal disease in nonpregnant adults, 1990-2007
    • Skoff T.H., Farley M.M., Petit S., et al. Increasing burden of invasive Group B streptococcal disease in nonpregnant adults, 1990-2007. Clin Infect Dis 2009, 49:85-92.
    • (2009) Clin Infect Dis , vol.49 , pp. 85-92
    • Skoff, T.H.1    Farley, M.M.2    Petit, S.3
  • 8
    • 33750569117 scopus 로고    scopus 로고
    • Staphylococcus aureus-associated skin and soft tissue infections in ambulatory care
    • McCaig L.F., McDonald L.C., Mandal S., Jernigan D.B. Staphylococcus aureus-associated skin and soft tissue infections in ambulatory care. Emerg Infect Dis 2006, 12:1715-1723.
    • (2006) Emerg Infect Dis , vol.12 , pp. 1715-1723
    • McCaig, L.F.1    McDonald, L.C.2    Mandal, S.3    Jernigan, D.B.4
  • 9
    • 27744448866 scopus 로고    scopus 로고
    • Practice guidelines for the diagnosis and management of skin and soft-tissue infections
    • Stevens D.L., Bisno A.L., Chambers H.F., et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005, 41:1373-1406.
    • (2005) Clin Infect Dis , vol.41 , pp. 1373-1406
    • Stevens, D.L.1    Bisno, A.L.2    Chambers, H.F.3
  • 10
    • 77957174142 scopus 로고    scopus 로고
    • Deaths: preliminary data for 2009
    • National Center for Health Statistics, Hyattsville, Md
    • Kochanek K.D., Xu J.Q., Murphy S.L., et al. Deaths: preliminary data for 2009. National Vital Statistics Reports 2011, 59:41-69. National Center for Health Statistics, Hyattsville, Md.
    • (2011) National Vital Statistics Reports , vol.59 , pp. 41-69
    • Kochanek, K.D.1    Xu, J.Q.2    Murphy, S.L.3
  • 11
    • 0036154233 scopus 로고    scopus 로고
    • Community-acquired pneumonia: management controversies, part 1; practical recommendations from the latest guidelines
    • Niederman M.S. Community-acquired pneumonia: management controversies, part 1; practical recommendations from the latest guidelines. J Respir Dis 2002, 23:10-17.
    • (2002) J Respir Dis , vol.23 , pp. 10-17
    • Niederman, M.S.1
  • 12
    • 30344451643 scopus 로고    scopus 로고
    • Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia
    • Kollef M.H., Shorr A., Tabak Y.P., et al. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 2005, 128:3854-3862.
    • (2005) Chest , vol.128 , pp. 3854-3862
    • Kollef, M.H.1    Shorr, A.2    Tabak, Y.P.3
  • 13
    • 67349102069 scopus 로고    scopus 로고
    • Comparative evaluation of epidemiology and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) USA300 infections causing community- and healthcare-associated infections
    • Moore C.L., Hingwe A., Donabedian S.M., et al. Comparative evaluation of epidemiology and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) USA300 infections causing community- and healthcare-associated infections. Int J Antimicrob Agents 2009, 34:148-155.
    • (2009) Int J Antimicrob Agents , vol.34 , pp. 148-155
    • Moore, C.L.1    Hingwe, A.2    Donabedian, S.M.3
  • 14
    • 33847155159 scopus 로고    scopus 로고
    • Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
    • Mandell L.A., Wunderink R.G., Anzueto A., et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007, 44(Suppl 2):S27-S72.
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 2
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 15
    • 0036829003 scopus 로고    scopus 로고
    • Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus
    • Lim D., Strynadka N.C. Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat Struct Biol 2002, 9:870-876.
    • (2002) Nat Struct Biol , vol.9 , pp. 870-876
    • Lim, D.1    Strynadka, N.C.2
  • 16
    • 34548737609 scopus 로고    scopus 로고
    • Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05
    • Steinkraus G., White R., Friedrich L. Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05. J Antimicrob Chemother 2007, 60:788-794.
    • (2007) J Antimicrob Chemother , vol.60 , pp. 788-794
    • Steinkraus, G.1    White, R.2    Friedrich, L.3
  • 17
    • 0030841073 scopus 로고    scopus 로고
    • Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility
    • Hiramatsu K., Hanaki H., Ino T., et al. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother 1997, 40:135-136.
    • (1997) J Antimicrob Chemother , vol.40 , pp. 135-136
    • Hiramatsu, K.1    Hanaki, H.2    Ino, T.3
  • 18
    • 0035495687 scopus 로고    scopus 로고
    • Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance
    • Hiramatsu K. Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance. Lancet Infect Dis 2001, 1:147-155.
    • (2001) Lancet Infect Dis , vol.1 , pp. 147-155
    • Hiramatsu, K.1
  • 19
    • 0035042571 scopus 로고    scopus 로고
    • Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus
    • Tenover F.C., Biddle J.W., Lancaster M.V. Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus. Emerg Infect Dis 2001, 7:327-332.
    • (2001) Emerg Infect Dis , vol.7 , pp. 327-332
    • Tenover, F.C.1    Biddle, J.W.2    Lancaster, M.V.3
  • 20
    • 0000214977 scopus 로고    scopus 로고
    • Vancomycin-resistant Staphylococcus aureus-Pennsylvania, 2002
    • Centers for Disease Control and Prevention
    • Vancomycin-resistant Staphylococcus aureus-Pennsylvania, 2002. MMWR Morb Mortal Wkly Rep 2002, 51:902. Centers for Disease Control and Prevention.
    • (2002) MMWR Morb Mortal Wkly Rep , vol.51 , pp. 902
  • 21
    • 33750950323 scopus 로고    scopus 로고
    • Increased vancomycin MICs for Staphylococcus aureus clinical isolates from a university hospital during a 5-year period
    • Wang G., Hindler J.F., Ward K.W., Bruckner D.A. Increased vancomycin MICs for Staphylococcus aureus clinical isolates from a university hospital during a 5-year period. J Clin Microbiol 2006, 44:3883-3886.
    • (2006) J Clin Microbiol , vol.44 , pp. 3883-3886
    • Wang, G.1    Hindler, J.F.2    Ward, K.W.3    Bruckner, D.A.4
  • 22
    • 84859582776 scopus 로고    scopus 로고
    • US Department of Health and Human Services, Accessed April 30, 2011
    • NDA 200327. NDA approval US Department of Health and Human Services, Accessed April 30, 2011. http://www.accessdata.fda.gov/drugsatfda_docs/appletter/2010/200327s000ltr.pdf.
    • NDA 200327. NDA approval
  • 23
    • 84859608904 scopus 로고    scopus 로고
    • Forest Laboratories, Inc, St Louis, Mo, Accessed April 30, 2011
    • Teflaro [package insert] 2011, Forest Laboratories, Inc, St Louis, Mo, Accessed April 30, 2011. http://www.frx.com/pi/teflaro_pi.pdf.
    • (2011) Teflaro [package insert]
  • 24
    • 23044471735 scopus 로고    scopus 로고
    • Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains
    • Sader H.S., Fritsche T.R., Kaniga K., et al. Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains. Antimicrob Agents Chemother 2005, 49:3501-3512.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3501-3512
    • Sader, H.S.1    Fritsche, T.R.2    Kaniga, K.3
  • 25
    • 77953797825 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates
    • Saravolatz L., Pawlak J., Johnson L. In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. Antimicrob Agents Chemother 2010, 54:3027-3030.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 3027-3030
    • Saravolatz, L.1    Pawlak, J.2    Johnson, L.3
  • 26
    • 12444281009 scopus 로고    scopus 로고
    • TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties
    • Ishikawa T., Matsunaga N., Tawada H., et al. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties. Bioorg Med Chem 2003, 11:2427-2437.
    • (2003) Bioorg Med Chem , vol.11 , pp. 2427-2437
    • Ishikawa, T.1    Matsunaga, N.2    Tawada, H.3
  • 27
    • 47749154496 scopus 로고    scopus 로고
    • Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics
    • Villegas-Estrada A., Lee M., Hesek D., et al. Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics. J Am Chem Soc 2008, 130:9212-9213.
    • (2008) J Am Chem Soc , vol.130 , pp. 9212-9213
    • Villegas-Estrada, A.1    Lee, M.2    Hesek, D.3
  • 28
    • 77952578858 scopus 로고    scopus 로고
    • Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae
    • Moisan H., Pruneau M., Malouin F. Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae. J Antimicrob Chemother 2010, 65:713-716.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 713-716
    • Moisan, H.1    Pruneau, M.2    Malouin, F.3
  • 29
    • 79956304769 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients attending Canadian hospitals in 2009
    • Karlowsky J.A., Adam H.J., Decorby M.R., et al. In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients attending Canadian hospitals in 2009. Antimicrob Agents Chemother 2011, 55:2837-2846.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2837-2846
    • Karlowsky, J.A.1    Adam, H.J.2    Decorby, M.R.3
  • 30
    • 50949105050 scopus 로고    scopus 로고
    • In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States
    • Ge Y., Biek D., Talbot G.H., Sahm D.F. In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. Antimicrob Agents Chemother 2008, 52:3398-3407.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3398-3407
    • Ge, Y.1    Biek, D.2    Talbot, G.H.3    Sahm, D.F.4
  • 31
    • 64549135399 scopus 로고    scopus 로고
    • Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia
    • Morrissey I., Ge Y., Janes R. Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia. Int J Antimicrob Agents 2009, 33:515-519.
    • (2009) Int J Antimicrob Agents , vol.33 , pp. 515-519
    • Morrissey, I.1    Ge, Y.2    Janes, R.3
  • 32
    • 62949159531 scopus 로고    scopus 로고
    • In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing
    • Brown S.D., Traczewski M.M. In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing. Antimicrob Agents Chemother 2009, 53:1271-1274.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1271-1274
    • Brown, S.D.1    Traczewski, M.M.2
  • 33
    • 78649453268 scopus 로고    scopus 로고
    • Ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study
    • Jones R.N., Mendes R.E., Sader H.S. Ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study. J Antimicrob Chemother 2010, 65:iv17-iv31.
    • (2010) J Antimicrob Chemother , vol.65
    • Jones, R.N.1    Mendes, R.E.2    Sader, H.S.3
  • 34
    • 40549135961 scopus 로고    scopus 로고
    • Antimicrobial activities of ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus
    • Sader H.S., Fritsche T.R., Jones R.N. Antimicrobial activities of ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2008, 52:1153-1155.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1153-1155
    • Sader, H.S.1    Fritsche, T.R.2    Jones, R.N.3
  • 35
    • 79955988800 scopus 로고    scopus 로고
    • Ceftaroline pharmacodynamics activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model
    • Zhanel G.G., Rossnagel E., Nichol K., et al. Ceftaroline pharmacodynamics activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model. J Antimicrob Chemother 2011, 66:1301-1305.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1301-1305
    • Zhanel, G.G.1    Rossnagel, E.2    Nichol, K.3
  • 36
    • 77952634376 scopus 로고    scopus 로고
    • Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States
    • Jacobs M.R., Good C.E., Windau A.R., et al. Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. Antimicrob Agents Chemother 2010, 54:2716-2719.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2716-2719
    • Jacobs, M.R.1    Good, C.E.2    Windau, A.R.3
  • 37
    • 59749096800 scopus 로고    scopus 로고
    • In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae
    • McGee L., Biek D., Ge Y., et al. In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 2009, 53:552-556.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 552-556
    • McGee, L.1    Biek, D.2    Ge, Y.3
  • 38
    • 67049086953 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including beta-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa
    • Vidaillac C., Leonard S.N., Sader H.S., et al. In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including beta-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2009, 53:2360-2366.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2360-2366
    • Vidaillac, C.1    Leonard, S.N.2    Sader, H.S.3
  • 40
    • 78650647462 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates
    • Snydman D.R., Jacobus N.V., McDermott L.A. In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates. Antimicrob Agents Chemother 2011, 55:421-425.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 421-425
    • Snydman, D.R.1    Jacobus, N.V.2    McDermott, L.A.3
  • 42
    • 0035038293 scopus 로고    scopus 로고
    • Current issues in gram-negative resistance: extended-spectrum beta-lactamases and inducible beta-lactamases
    • Fung H.B., Kuczynski S., Finch D.A., Ramos L. Current issues in gram-negative resistance: extended-spectrum beta-lactamases and inducible beta-lactamases. J Pharm Pract 2001, 14:6-17.
    • (2001) J Pharm Pract , vol.14 , pp. 6-17
    • Fung, H.B.1    Kuczynski, S.2    Finch, D.A.3    Ramos, L.4
  • 43
    • 84859582775 scopus 로고    scopus 로고
    • Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract Athomampersa
    • Jacqueline C, Caillon J, Miegeville AF, et al. Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1938.
    • (2006)
    • Jacqueline, C.1    Caillon, J.2    Miegeville, A.F.3
  • 44
    • 84859619204 scopus 로고    scopus 로고
    • Efficacy of ceftaroline fosamil against penicillin-sensitive and -resistant Streptococcus pneumoniae in an experimental rabbit meningitis model
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 13-14; Boston, Mass. Abstract B-702
    • Cottagnoud P, Acosta F, Biek D, et al. Efficacy of ceftaroline fosamil against penicillin-sensitive and -resistant Streptococcus pneumoniae in an experimental rabbit meningitis model. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 13-14, 2010; Boston, Mass. Abstract B-702.
    • (2010)
    • Cottagnoud, P.1    Acosta, F.2    Biek, D.3
  • 45
    • 84859619203 scopus 로고    scopus 로고
    • Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract A-1936.
    • Ge Y, Redman R, Floren L, et al. Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1936.
    • (2006)
    • Ge, Y.1    Redman, R.2    Floren, L.3
  • 46
    • 84859582774 scopus 로고    scopus 로고
    • The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1937.
    • Ge Y, Redman R, Floren L, et al. The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1937.
    • (2006)
    • Ge, Y.1    Redman, R.2    Floren, L.3
  • 47
    • 84859619202 scopus 로고    scopus 로고
    • Population pharmacokinetics of ceftaroline in healthy and renally impaired subjects
    • Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, San Francisco, Calif. Abstract A1-004
    • Van Wart SA, Forrest A, Bhavnani SM, et al. Population pharmacokinetics of ceftaroline in healthy and renally impaired subjects. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1-004.
    • (2009)
    • Van Wart, S.A.1    Forrest, A.2    Bhavnani, S.M.3
  • 48
    • 84859579341 scopus 로고    scopus 로고
    • In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903M)
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1935.
    • Ge Y, Hubbel A. In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903M). Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1935.
    • (2006)
    • Ge, Y.1    Hubbel, A.2
  • 49
    • 84859619205 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI)
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1939.
    • Ge Y, Thye D, Liao S, Talbot GH. Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI). Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1939.
    • (2006)
    • Ge, Y.1    Thye, D.2    Liao, S.3    Talbot, G.H.4
  • 50
    • 84859619206 scopus 로고    scopus 로고
    • An open-label pharmacokinetic (PK), safety, and tolerability study of single intravenous (IV) doses of ceftaroline (CPT) in subjects with normal renal function or severe renal impairment
    • Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1thomampersand
    • Riccobene T, Fang E, Thye D. An open-label pharmacokinetic (PK), safety, and tolerability study of single intravenous (IV) doses of ceftaroline (CPT) in subjects with normal renal function or severe renal impairment. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1-003.
    • Riccobene, T.1    Fang, E.2    Thye, D.3
  • 51
    • 79954568823 scopus 로고    scopus 로고
    • An open-label pharmacokinetic, safety and tolerability study of single-dose intravenous ceftaroline in subjects with end-stage renal disease on intermittent haemodialysis
    • Riccobene T., Jakate A., Rank D., Thye D. An open-label pharmacokinetic, safety and tolerability study of single-dose intravenous ceftaroline in subjects with end-stage renal disease on intermittent haemodialysis. Clin Microbiol Infect 2009, 15(Suppl s4):S407.
    • (2009) Clin Microbiol Infect , vol.15 , Issue.SUPPL. S4
    • Riccobene, T.1    Jakate, A.2    Rank, D.3    Thye, D.4
  • 53
    • 84859574080 scopus 로고    scopus 로고
    • Open-label pharmacokinetic, safety, and tolerability study of single intravenous doses of ceftaroline in healthy elderly and healthy young adult subjects
    • Abstract presented at: 2009 Midyear Clinical Meeting of the American Society of Health-System Pharmacists; December 6-10; Las Vegas, NV. Abstract 3-161.
    • Riccobene T, Jakate A, Rank D, Thye D. Open-label pharmacokinetic, safety, and tolerability study of single intravenous doses of ceftaroline in healthy elderly and healthy young adult subjects. Abstract presented at: 2009 Midyear Clinical Meeting of the American Society of Health-System Pharmacists; December 6-10, 2009; Las Vegas, NV. Abstract 3-161.
    • (2009)
    • Riccobene, T.1    Jakate, A.2    Rank, D.3    Thye, D.4
  • 54
    • 84859562509 scopus 로고    scopus 로고
    • A single- and multiple-dose study to determine the safety, tolerability, and pharmacokinetics (PK) of ceftaroline (CPT) administered by intramuscular (IM) injection to healthy subjects
    • Abstract presented at: 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/46th Annual Meeting of the Infectious Diseases Society of America; October 25-28; Washington, DC. Abstract A-1888.
    • Riccobene T, Fang E, Thye D. A single- and multiple-dose study to determine the safety, tolerability, and pharmacokinetics (PK) of ceftaroline (CPT) administered by intramuscular (IM) injection to healthy subjects. Abstract presented at: 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/46th Annual Meeting of the Infectious Diseases Society of America; October 25-28, 2008; Washington, DC. Abstract A-1888.
    • (2008)
    • Riccobene, T.1    Fang, E.2    Thye, D.3
  • 56
    • 29444443515 scopus 로고    scopus 로고
    • Evaluation of PPI-090M (T91825)., a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests
    • Jones R.N., Fritsche T.R., Ge Y., et al. Evaluation of PPI-090M (T91825)., a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests. J Antimicrob Chemother 2005, 56:1047-1052.
    • (2005) J Antimicrob Chemother , vol.56 , pp. 1047-1052
    • Jones, R.N.1    Fritsche, T.R.2    Ge, Y.3
  • 57
    • 70350326281 scopus 로고    scopus 로고
    • In vitro activity of ceftaroline against methicillin-resistant Staphylococcus aureus and heterogeneous vancomycin-intermediate S. aureus in a hollow fiber model
    • Vidaillac C., Leonard S.N., Rybak M.J. In vitro activity of ceftaroline against methicillin-resistant Staphylococcus aureus and heterogeneous vancomycin-intermediate S. aureus in a hollow fiber model. Antimicrob Agents Chemother 2009, 53(11):4712-4717.
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.11 , pp. 4712-4717
    • Vidaillac, C.1    Leonard, S.N.2    Rybak, M.J.3
  • 58
    • 3843081646 scopus 로고    scopus 로고
    • In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599
    • Iizawa Y., Nagai J., Ishikawa T., et al. In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599. J Infect Chemother 2004, 10:146-156.
    • (2004) J Infect Chemother , vol.10 , pp. 146-156
    • Iizawa, Y.1    Nagai, J.2    Ishikawa, T.3
  • 59
    • 84859619209 scopus 로고    scopus 로고
    • Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae
    • Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract E-0121
    • Sader HS, Moet G, Fritsche TR, Jones RN. Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract E-0121.
    • (2006)
    • Sader, H.S.1    Moet, G.2    Fritsche, T.R.3    Jones, R.N.4
  • 60
    • 35948962693 scopus 로고    scopus 로고
    • In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model
    • Jacqueline C., Caillon J., Le Mabecque V., et al. In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model. Antimicrob Agents Chemother 2007, 51:3397-3400.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3397-3400
    • Jacqueline, C.1    Caillon, J.2    Le Mabecque, V.3
  • 61
    • 70349349051 scopus 로고    scopus 로고
    • Postantibiotic effect of ceftaroline against gram-positive organisms
    • Pankuch G.A., Appelbaum P.C. Postantibiotic effect of ceftaroline against gram-positive organisms. Antimicrob Agents Chemother 2009, 53:4537-4539.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4537-4539
    • Pankuch, G.A.1    Appelbaum, P.C.2
  • 62
    • 33645766499 scopus 로고    scopus 로고
    • Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target
    • Andes D., Craig W.A. Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target. Antimicrob Agents Chemother 2006, 50:1376-1383.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1376-1383
    • Andes, D.1    Craig, W.A.2
  • 63
    • 77951764966 scopus 로고    scopus 로고
    • In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates
    • Vidaillac C., Leonard S.N., Rybak M.J. In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates. Int J Antimicrob Agents 2010, 35:527-530.
    • (2010) Int J Antimicrob Agents , vol.35 , pp. 527-530
    • Vidaillac, C.1    Leonard, S.N.2    Rybak, M.J.3
  • 64
    • 4444347175 scopus 로고    scopus 로고
    • In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor
    • Bonnefoy A., Dupuis-Hamelin C., Steier V., et al. In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor. J Antimicrob Chemother 2004, 54:410-417.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 410-417
    • Bonnefoy, A.1    Dupuis-Hamelin, C.2    Steier, V.3
  • 65
    • 84859619208 scopus 로고    scopus 로고
    • Comparison of the antibacterial effects of two dosing regimens of ceftaroline in combination with NXL104 against Enterobacteriaceae
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-1377
    • Bowker K, Noel A, Elliott H, et al. Comparison of the antibacterial effects of two dosing regimens of ceftaroline in combination with NXL104 against Enterobacteriaceae. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1377.
    • (2010)
    • Bowker, K.1    Noel, A.2    Elliott, H.3
  • 66
    • 84859579343 scopus 로고    scopus 로고
    • Pharmacodynamics (PD) of ceftaroline (CPT) fosamil plus 1:1 and 2:1 ratios of NXL104 (NXL) against Enterobacteriaceae (ENT) containing ESBLs and carbapenemases (KPCs) in neutropenic mouse thighs
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-138
    • Craig WA, Andes DR. Pharmacodynamics (PD) of ceftaroline (CPT) fosamil plus 1:1 and 2:1 ratios of NXL104 (NXL) against Enterobacteriaceae (ENT) containing ESBLs and carbapenemases (KPCs) in neutropenic mouse thighs. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1387.
    • (2010)
    • Craig, W.A.1    Andes, D.R.2
  • 67
    • 84859579342 scopus 로고    scopus 로고
    • In vivo antibacterial efficacy of ceftaroline (CPT) combined with the beta-lactamase inhibitor NXL104 in a murine septicemia model
    • Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; San Francisco, Calif. Abstract B-1339a.
    • Levasseur P, Girard A-M, Williams G, et al. In vivo antibacterial efficacy of ceftaroline (CPT) combined with the beta-lactamase inhibitor NXL104 in a murine septicemia model. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract B-1339a.
    • (2009)
    • Levasseur, P.1    Girard, A.-M.2    Williams, G.3
  • 68
    • 79959280244 scopus 로고    scopus 로고
    • In vivo efficacy of a human-simulated regimen of ceftaroline fosamil combined with NXL104 (CXL) against ESBL- and non-ESBL-producing Enterobacteriaceae
    • Wiskirchen D.E., Crandon J.L., Furtado G.H., et al. In vivo efficacy of a human-simulated regimen of ceftaroline fosamil combined with NXL104 (CXL) against ESBL- and non-ESBL-producing Enterobacteriaceae. Antimicrob Agents Chemother 2011, 55:3220-3225.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3220-3225
    • Wiskirchen, D.E.1    Crandon, J.L.2    Furtado, G.H.3
  • 69
    • 84859562510 scopus 로고    scopus 로고
    • Comparative time-kill analysis of ceftaroline (CPT) with and without NXL104 (NXL) against anaerobes
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-1396
    • Credito K, Ednie LM, Appelbaum PC. Comparative time-kill analysis of ceftaroline (CPT) with and without NXL104 (NXL) against anaerobes. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1396.
    • (2010)
    • Credito, K.1    Ednie, L.M.2    Appelbaum, P.C.3
  • 70
    • 79954622500 scopus 로고    scopus 로고
    • FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
    • Low D.E., File T.M., Eckburg P.B., et al. FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii33-iii44.
    • (2011) J Antimicrob Chemother , vol.66
    • Low, D.E.1    File, T.M.2    Eckburg, P.B.3
  • 72
    • 84859582777 scopus 로고    scopus 로고
    • Multistep resistance development studies of ceftaroline (CPT) with Streptococcus pneumoniae, Streptococcus pyogenes, staphylococci, and enterococci
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, Boston MA. Abstract E-813
    • Clark C, Kosowska-Shick K, McGhee P, Appelbaum P. Multistep resistance development studies of ceftaroline (CPT) with Streptococcus pneumoniae, Streptococcus pyogenes, staphylococci, and enterococci. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston MA. Abstract E-813.
    • (2010)
    • Clark, C.1    Kosowska-Shick, K.2    McGhee, P.3    Appelbaum, P.4
  • 73
    • 84859619207 scopus 로고    scopus 로고
    • Multistep resistance development studies of ceftaroline (CPT) with Haemophilus influenzae and Moraxella catarrhalis
    • Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract E-814
    • Clark C, Kosowska-Shick K, McGhee P, Appelbaum P. Multistep resistance development studies of ceftaroline (CPT) with Haemophilus influenzae and Moraxella catarrhalis. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract E-814.
    • (2010)
    • Clark, C.1    Kosowska-Shick, K.2    McGhee, P.3    Appelbaum, P.4
  • 74
    • 84859577671 scopus 로고    scopus 로고
    • Ceftaroline vs ceftriaxone in a highly penicillin-resistant pneumococcal pneumonia model
    • Croisier-Bertin D., Piroth L., Charles P.E., et al. Ceftaroline vs ceftriaxone in a highly penicillin-resistant pneumococcal pneumonia model. Clin Microbiol Infect 2009, 15(Suppl s4):S81.
    • (2009) Clin Microbiol Infect , vol.15 , Issue.SUPPL. S4
    • Croisier-Bertin, D.1    Piroth, L.2    Charles, P.E.3
  • 75
    • 84859579344 scopus 로고    scopus 로고
    • Ceftaroline is superior to cefepime against a Klebsiella pneumoniae strain an experimental rabbit meningitis model
    • Cottagnoud P., Stucki A., Accosta F., et al. Ceftaroline is superior to cefepime against a Klebsiella pneumoniae strain an experimental rabbit meningitis model. Clin Microbiol Infect 2010, 16(Suppl s2):S4565.
    • (2010) Clin Microbiol Infect , vol.16 , Issue.SUPPL. S2
    • Cottagnoud, P.1    Stucki, A.2    Accosta, F.3
  • 76
    • 79952781069 scopus 로고    scopus 로고
    • Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus
    • Jacqueline C., Amador G., Batard E., et al. Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. J Antimicrob Chemother 2011, 66:863-866.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 863-866
    • Jacqueline, C.1    Amador, G.2    Batard, E.3
  • 77
    • 77957241721 scopus 로고    scopus 로고
    • Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model
    • Jacqueline C., Caillon J., Batard E., et al. Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model. J Antimicrob Chemother 2010, 65:2264-2265.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 2264-2265
    • Jacqueline, C.1    Caillon, J.2    Batard, E.3
  • 78
    • 77954724135 scopus 로고    scopus 로고
    • Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis
    • Jacqueline C., Amador G., Caillon J., et al. Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis. J Antimicrob Chemother 2010, 65:1749-1752.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1749-1752
    • Jacqueline, C.1    Amador, G.2    Caillon, J.3
  • 79
    • 34948854764 scopus 로고    scopus 로고
    • Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections
    • Talbot G.H., Thye D., Das A., Ge Y. Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections. Antimicrob Agents Chemother 2007, 51:3612-3616.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3612-3616
    • Talbot, G.H.1    Thye, D.2    Das, A.3    Ge, Y.4
  • 80
    • 78649485323 scopus 로고    scopus 로고
    • CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
    • Corey G.R., Wilcox M.H., Talbot G.H., et al. CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv41-iv51.
    • (2010) J Antimicrob Chemother , vol.65
    • Corey, G.R.1    Wilcox, M.H.2    Talbot, G.H.3
  • 81
    • 78649489951 scopus 로고    scopus 로고
    • CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
    • Wilcox M.H., Corey G.R., Talbot G.H., et al. CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv53-iv 65.
    • (2010) J Antimicrob Chemother , vol.65
    • Wilcox, M.H.1    Corey, G.R.2    Talbot, G.H.3
  • 82
    • 79954622500 scopus 로고    scopus 로고
    • FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
    • File T.M., Low D.E., Eckburg P.B., et al. FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii19-iii32.
    • (2011) J Antimicrob Chemother , vol.66
    • File, T.M.1    Low, D.E.2    Eckburg, P.B.3
  • 83
    • 77955957827 scopus 로고    scopus 로고
    • Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection
    • Corey G.R., Wilcox M., Talbot G.H., et al. Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. Clin Infect Dis 2010, 51:641-650.
    • (2010) Clin Infect Dis , vol.51 , pp. 641-650
    • Corey, G.R.1    Wilcox, M.2    Talbot, G.H.3
  • 84
    • 78649873377 scopus 로고    scopus 로고
    • Integrated analysis of FOCUS 1 and FOCUS 2: randomized, double-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia
    • File T.M., Low D.E., Eckburg P.B., et al. Integrated analysis of FOCUS 1 and FOCUS 2: randomized, double-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia. Clin Infect Dis 2010, 51:1395-1405.
    • (2010) Clin Infect Dis , vol.51 , pp. 1395-1405
    • File, T.M.1    Low, D.E.2    Eckburg, P.B.3
  • 88
    • 79954622204 scopus 로고    scopus 로고
    • Review of ceftaroline fosamil microbiology: integrated FOCUS studies
    • Critchley I.A., Eckburg P.B., Jandourek A., et al. Review of ceftaroline fosamil microbiology: integrated FOCUS studies. J Antimicrob Chemother 2011, 66:iii45-iii51.
    • (2011) J Antimicrob Chemother , vol.66
    • Critchley, I.A.1    Eckburg, P.B.2    Jandourek, A.3
  • 89
    • 78649453055 scopus 로고    scopus 로고
    • Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
    • Corrado M.L. Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv67-iv 71.
    • (2010) J Antimicrob Chemother , vol.65
    • Corrado, M.L.1
  • 90
    • 79954568574 scopus 로고    scopus 로고
    • Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia
    • Rank D.R., Friedland H.D., Laudano J.B. Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii53-iii59.
    • (2011) J Antimicrob Chemother , vol.66
    • Rank, D.R.1    Friedland, H.D.2    Laudano, J.B.3
  • 91
    • 84859564541 scopus 로고    scopus 로고
    • Thomson Medical Economics, Montvale, NJ
    • 2011 Drug Topics Red Book 2011, Thomson Medical Economics, Montvale, NJ.
    • (2011) 2011 Drug Topics Red Book
  • 92
    • 62449183879 scopus 로고    scopus 로고
    • Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists
    • Rybak M., Lomaestro B., Rotschafer J.C., et al. Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm 2009, 66:82-98.
    • (2009) Am J Health Syst Pharm , vol.66 , pp. 82-98
    • Rybak, M.1    Lomaestro, B.2    Rotschafer, J.C.3


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