-
1
-
-
2342595765
-
Trends in antimicrobial drug development: implications for the future
-
Spellberg B., Powers J.H., Brass E.P., et al. Trends in antimicrobial drug development: implications for the future. Clin Infect Dis 2004, 28:1279-1286.
-
(2004)
Clin Infect Dis
, vol.28
, pp. 1279-1286
-
-
Spellberg, B.1
Powers, J.H.2
Brass, E.P.3
-
2
-
-
31044456290
-
Changes in the epidemiology of Staphylococcus aureus in intensive care units in US hospitals, 1992-2003
-
Klevens R.M., Edwards J.R., Tenover F.C., et al. Changes in the epidemiology of Staphylococcus aureus in intensive care units in US hospitals, 1992-2003. Clin Infect Dis 2006, 42:389-391.
-
(2006)
Clin Infect Dis
, vol.42
, pp. 389-391
-
-
Klevens, R.M.1
Edwards, J.R.2
Tenover, F.C.3
-
3
-
-
19344368919
-
Methicillin-resistant Staphylococcus aureus in community-acquired skin infections
-
Moran G.J., Amii R.N., Abrahamian F.M., Talan D.A. Methicillin-resistant Staphylococcus aureus in community-acquired skin infections. Emerg Infect Dis 2005, 11:928-930.
-
(2005)
Emerg Infect Dis
, vol.11
, pp. 928-930
-
-
Moran, G.J.1
Amii, R.N.2
Abrahamian, F.M.3
Talan, D.A.4
-
4
-
-
33747343208
-
Methicillin-resistant S. aureus infections among patients in the emergency department
-
Moran G.J., Krishnadasan A., Gorwitz R.J., et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N Engl J Med 2006, 355:666-674.
-
(2006)
N Engl J Med
, vol.355
, pp. 666-674
-
-
Moran, G.J.1
Krishnadasan, A.2
Gorwitz, R.J.3
-
5
-
-
35349019173
-
Invasive methicillin-resistant Staphylococcus aureus infections in the Unites States
-
Klevens R.M., Morrison M.A., Nadle J., et al. Invasive methicillin-resistant Staphylococcus aureus infections in the Unites States. JAMA 2007, 298:1763-1771.
-
(2007)
JAMA
, vol.298
, pp. 1763-1771
-
-
Klevens, R.M.1
Morrison, M.A.2
Nadle, J.3
-
6
-
-
58749108809
-
Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005
-
Richter S.S., Heilmann K.P., Dohrn C.L., et al. Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004-2005. Clin Infect Dis 2009, 48:e23-e33.
-
(2009)
Clin Infect Dis
, vol.48
-
-
Richter, S.S.1
Heilmann, K.P.2
Dohrn, C.L.3
-
7
-
-
66949168809
-
Increasing burden of invasive Group B streptococcal disease in nonpregnant adults, 1990-2007
-
Skoff T.H., Farley M.M., Petit S., et al. Increasing burden of invasive Group B streptococcal disease in nonpregnant adults, 1990-2007. Clin Infect Dis 2009, 49:85-92.
-
(2009)
Clin Infect Dis
, vol.49
, pp. 85-92
-
-
Skoff, T.H.1
Farley, M.M.2
Petit, S.3
-
8
-
-
33750569117
-
Staphylococcus aureus-associated skin and soft tissue infections in ambulatory care
-
McCaig L.F., McDonald L.C., Mandal S., Jernigan D.B. Staphylococcus aureus-associated skin and soft tissue infections in ambulatory care. Emerg Infect Dis 2006, 12:1715-1723.
-
(2006)
Emerg Infect Dis
, vol.12
, pp. 1715-1723
-
-
McCaig, L.F.1
McDonald, L.C.2
Mandal, S.3
Jernigan, D.B.4
-
9
-
-
27744448866
-
Practice guidelines for the diagnosis and management of skin and soft-tissue infections
-
Stevens D.L., Bisno A.L., Chambers H.F., et al. Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis 2005, 41:1373-1406.
-
(2005)
Clin Infect Dis
, vol.41
, pp. 1373-1406
-
-
Stevens, D.L.1
Bisno, A.L.2
Chambers, H.F.3
-
10
-
-
77957174142
-
Deaths: preliminary data for 2009
-
National Center for Health Statistics, Hyattsville, Md
-
Kochanek K.D., Xu J.Q., Murphy S.L., et al. Deaths: preliminary data for 2009. National Vital Statistics Reports 2011, 59:41-69. National Center for Health Statistics, Hyattsville, Md.
-
(2011)
National Vital Statistics Reports
, vol.59
, pp. 41-69
-
-
Kochanek, K.D.1
Xu, J.Q.2
Murphy, S.L.3
-
11
-
-
0036154233
-
Community-acquired pneumonia: management controversies, part 1; practical recommendations from the latest guidelines
-
Niederman M.S. Community-acquired pneumonia: management controversies, part 1; practical recommendations from the latest guidelines. J Respir Dis 2002, 23:10-17.
-
(2002)
J Respir Dis
, vol.23
, pp. 10-17
-
-
Niederman, M.S.1
-
12
-
-
30344451643
-
Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia
-
Kollef M.H., Shorr A., Tabak Y.P., et al. Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 2005, 128:3854-3862.
-
(2005)
Chest
, vol.128
, pp. 3854-3862
-
-
Kollef, M.H.1
Shorr, A.2
Tabak, Y.P.3
-
13
-
-
67349102069
-
Comparative evaluation of epidemiology and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) USA300 infections causing community- and healthcare-associated infections
-
Moore C.L., Hingwe A., Donabedian S.M., et al. Comparative evaluation of epidemiology and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) USA300 infections causing community- and healthcare-associated infections. Int J Antimicrob Agents 2009, 34:148-155.
-
(2009)
Int J Antimicrob Agents
, vol.34
, pp. 148-155
-
-
Moore, C.L.1
Hingwe, A.2
Donabedian, S.M.3
-
14
-
-
33847155159
-
Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults
-
Mandell L.A., Wunderink R.G., Anzueto A., et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007, 44(Suppl 2):S27-S72.
-
(2007)
Clin Infect Dis
, vol.44
, Issue.SUPPL. 2
-
-
Mandell, L.A.1
Wunderink, R.G.2
Anzueto, A.3
-
15
-
-
0036829003
-
Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus
-
Lim D., Strynadka N.C. Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat Struct Biol 2002, 9:870-876.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 870-876
-
-
Lim, D.1
Strynadka, N.C.2
-
16
-
-
34548737609
-
Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05
-
Steinkraus G., White R., Friedrich L. Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05. J Antimicrob Chemother 2007, 60:788-794.
-
(2007)
J Antimicrob Chemother
, vol.60
, pp. 788-794
-
-
Steinkraus, G.1
White, R.2
Friedrich, L.3
-
17
-
-
0030841073
-
Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility
-
Hiramatsu K., Hanaki H., Ino T., et al. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother 1997, 40:135-136.
-
(1997)
J Antimicrob Chemother
, vol.40
, pp. 135-136
-
-
Hiramatsu, K.1
Hanaki, H.2
Ino, T.3
-
18
-
-
0035495687
-
Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance
-
Hiramatsu K. Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance. Lancet Infect Dis 2001, 1:147-155.
-
(2001)
Lancet Infect Dis
, vol.1
, pp. 147-155
-
-
Hiramatsu, K.1
-
19
-
-
0035042571
-
Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus
-
Tenover F.C., Biddle J.W., Lancaster M.V. Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus. Emerg Infect Dis 2001, 7:327-332.
-
(2001)
Emerg Infect Dis
, vol.7
, pp. 327-332
-
-
Tenover, F.C.1
Biddle, J.W.2
Lancaster, M.V.3
-
20
-
-
0000214977
-
Vancomycin-resistant Staphylococcus aureus-Pennsylvania, 2002
-
Centers for Disease Control and Prevention
-
Vancomycin-resistant Staphylococcus aureus-Pennsylvania, 2002. MMWR Morb Mortal Wkly Rep 2002, 51:902. Centers for Disease Control and Prevention.
-
(2002)
MMWR Morb Mortal Wkly Rep
, vol.51
, pp. 902
-
-
-
21
-
-
33750950323
-
Increased vancomycin MICs for Staphylococcus aureus clinical isolates from a university hospital during a 5-year period
-
Wang G., Hindler J.F., Ward K.W., Bruckner D.A. Increased vancomycin MICs for Staphylococcus aureus clinical isolates from a university hospital during a 5-year period. J Clin Microbiol 2006, 44:3883-3886.
-
(2006)
J Clin Microbiol
, vol.44
, pp. 3883-3886
-
-
Wang, G.1
Hindler, J.F.2
Ward, K.W.3
Bruckner, D.A.4
-
22
-
-
84859582776
-
-
US Department of Health and Human Services, Accessed April 30, 2011
-
NDA 200327. NDA approval US Department of Health and Human Services, Accessed April 30, 2011. http://www.accessdata.fda.gov/drugsatfda_docs/appletter/2010/200327s000ltr.pdf.
-
NDA 200327. NDA approval
-
-
-
23
-
-
84859608904
-
-
Forest Laboratories, Inc, St Louis, Mo, Accessed April 30, 2011
-
Teflaro [package insert] 2011, Forest Laboratories, Inc, St Louis, Mo, Accessed April 30, 2011. http://www.frx.com/pi/teflaro_pi.pdf.
-
(2011)
Teflaro [package insert]
-
-
-
24
-
-
23044471735
-
Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains
-
Sader H.S., Fritsche T.R., Kaniga K., et al. Antimicrobial activity and spectrum of PPI-0903M (T-91825), a novel cephalosporin, tested against a worldwide collection of clinical strains. Antimicrob Agents Chemother 2005, 49:3501-3512.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3501-3512
-
-
Sader, H.S.1
Fritsche, T.R.2
Kaniga, K.3
-
25
-
-
77953797825
-
In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates
-
Saravolatz L., Pawlak J., Johnson L. In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates. Antimicrob Agents Chemother 2010, 54:3027-3030.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3027-3030
-
-
Saravolatz, L.1
Pawlak, J.2
Johnson, L.3
-
26
-
-
12444281009
-
TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties
-
Ishikawa T., Matsunaga N., Tawada H., et al. TAK-599, a novel N-phosphono type prodrug of anti-MRSA cephalosporin T-91825: synthesis, physicochemical and pharmacological properties. Bioorg Med Chem 2003, 11:2427-2437.
-
(2003)
Bioorg Med Chem
, vol.11
, pp. 2427-2437
-
-
Ishikawa, T.1
Matsunaga, N.2
Tawada, H.3
-
27
-
-
47749154496
-
Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics
-
Villegas-Estrada A., Lee M., Hesek D., et al. Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics. J Am Chem Soc 2008, 130:9212-9213.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 9212-9213
-
-
Villegas-Estrada, A.1
Lee, M.2
Hesek, D.3
-
28
-
-
77952578858
-
Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae
-
Moisan H., Pruneau M., Malouin F. Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae. J Antimicrob Chemother 2010, 65:713-716.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 713-716
-
-
Moisan, H.1
Pruneau, M.2
Malouin, F.3
-
29
-
-
79956304769
-
In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients attending Canadian hospitals in 2009
-
Karlowsky J.A., Adam H.J., Decorby M.R., et al. In vitro activity of ceftaroline against gram-positive and gram-negative pathogens isolated from patients attending Canadian hospitals in 2009. Antimicrob Agents Chemother 2011, 55:2837-2846.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2837-2846
-
-
Karlowsky, J.A.1
Adam, H.J.2
Decorby, M.R.3
-
30
-
-
50949105050
-
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States
-
Ge Y., Biek D., Talbot G.H., Sahm D.F. In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. Antimicrob Agents Chemother 2008, 52:3398-3407.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 3398-3407
-
-
Ge, Y.1
Biek, D.2
Talbot, G.H.3
Sahm, D.F.4
-
31
-
-
64549135399
-
Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia
-
Morrissey I., Ge Y., Janes R. Activity of the new cephalosporin ceftaroline against bacteraemia isolates from patients with community-acquired pneumonia. Int J Antimicrob Agents 2009, 33:515-519.
-
(2009)
Int J Antimicrob Agents
, vol.33
, pp. 515-519
-
-
Morrissey, I.1
Ge, Y.2
Janes, R.3
-
32
-
-
62949159531
-
In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing
-
Brown S.D., Traczewski M.M. In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing. Antimicrob Agents Chemother 2009, 53:1271-1274.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1271-1274
-
-
Brown, S.D.1
Traczewski, M.M.2
-
33
-
-
78649453268
-
Ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study
-
Jones R.N., Mendes R.E., Sader H.S. Ceftaroline activity against pathogens associated with complicated skin and skin structure infections: results from an international surveillance study. J Antimicrob Chemother 2010, 65:iv17-iv31.
-
(2010)
J Antimicrob Chemother
, vol.65
-
-
Jones, R.N.1
Mendes, R.E.2
Sader, H.S.3
-
34
-
-
40549135961
-
Antimicrobial activities of ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus
-
Sader H.S., Fritsche T.R., Jones R.N. Antimicrobial activities of ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2008, 52:1153-1155.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1153-1155
-
-
Sader, H.S.1
Fritsche, T.R.2
Jones, R.N.3
-
35
-
-
79955988800
-
Ceftaroline pharmacodynamics activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model
-
Zhanel G.G., Rossnagel E., Nichol K., et al. Ceftaroline pharmacodynamics activity versus community-associated and healthcare-associated methicillin-resistant Staphylococcus aureus, heteroresistant vancomycin-intermediate S. aureus, vancomycin-intermediate S. aureus and vancomycin-resistant S. aureus using an in vitro model. J Antimicrob Chemother 2011, 66:1301-1305.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 1301-1305
-
-
Zhanel, G.G.1
Rossnagel, E.2
Nichol, K.3
-
36
-
-
77952634376
-
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States
-
Jacobs M.R., Good C.E., Windau A.R., et al. Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States. Antimicrob Agents Chemother 2010, 54:2716-2719.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2716-2719
-
-
Jacobs, M.R.1
Good, C.E.2
Windau, A.R.3
-
37
-
-
59749096800
-
In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae
-
McGee L., Biek D., Ge Y., et al. In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 2009, 53:552-556.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 552-556
-
-
McGee, L.1
Biek, D.2
Ge, Y.3
-
38
-
-
67049086953
-
In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including beta-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa
-
Vidaillac C., Leonard S.N., Sader H.S., et al. In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including beta-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother 2009, 53:2360-2366.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2360-2366
-
-
Vidaillac, C.1
Leonard, S.N.2
Sader, H.S.3
-
40
-
-
78650647462
-
In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates
-
Snydman D.R., Jacobus N.V., McDermott L.A. In vitro activity of ceftaroline against a broad spectrum of recent clinical anaerobic isolates. Antimicrob Agents Chemother 2011, 55:421-425.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 421-425
-
-
Snydman, D.R.1
Jacobus, N.V.2
McDermott, L.A.3
-
41
-
-
77950161157
-
In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria
-
Citron D.M., Tyrrell K.L., Merriam C.V., Goldstein E.J. In vitro activity of ceftaroline against 623 diverse strains of anaerobic bacteria. Antimicrob Agents Chemother 2010, 54:1627-1632.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1627-1632
-
-
Citron, D.M.1
Tyrrell, K.L.2
Merriam, C.V.3
Goldstein, E.J.4
-
42
-
-
0035038293
-
Current issues in gram-negative resistance: extended-spectrum beta-lactamases and inducible beta-lactamases
-
Fung H.B., Kuczynski S., Finch D.A., Ramos L. Current issues in gram-negative resistance: extended-spectrum beta-lactamases and inducible beta-lactamases. J Pharm Pract 2001, 14:6-17.
-
(2001)
J Pharm Pract
, vol.14
, pp. 6-17
-
-
Fung, H.B.1
Kuczynski, S.2
Finch, D.A.3
Ramos, L.4
-
43
-
-
84859582775
-
Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract Athomampersa
-
Jacqueline C, Caillon J, Miegeville AF, et al. Penetration of ceftaroline (PPI-0903), a new cephalosporin, into lung tissues: measurement of plasma and lung tissue concentrations after a short IV infusion in the rabbit. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1938.
-
(2006)
-
-
Jacqueline, C.1
Caillon, J.2
Miegeville, A.F.3
-
44
-
-
84859619204
-
Efficacy of ceftaroline fosamil against penicillin-sensitive and -resistant Streptococcus pneumoniae in an experimental rabbit meningitis model
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 13-14; Boston, Mass. Abstract B-702
-
Cottagnoud P, Acosta F, Biek D, et al. Efficacy of ceftaroline fosamil against penicillin-sensitive and -resistant Streptococcus pneumoniae in an experimental rabbit meningitis model. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 13-14, 2010; Boston, Mass. Abstract B-702.
-
(2010)
-
-
Cottagnoud, P.1
Acosta, F.2
Biek, D.3
-
45
-
-
84859619203
-
Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract A-1936.
-
Ge Y, Redman R, Floren L, et al. Single-dose pharmacokinetics (PK) of ceftaroline (PPI-0903) in healthy subjects. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1936.
-
(2006)
-
-
Ge, Y.1
Redman, R.2
Floren, L.3
-
46
-
-
84859582774
-
The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1937.
-
Ge Y, Redman R, Floren L, et al. The pharmacokinetics (PK) and safety of ceftaroline (PPI-0903) in healthy subjects receiving multiple-dose intravenous (IV) infusions. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1937.
-
(2006)
-
-
Ge, Y.1
Redman, R.2
Floren, L.3
-
47
-
-
84859619202
-
Population pharmacokinetics of ceftaroline in healthy and renally impaired subjects
-
Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, San Francisco, Calif. Abstract A1-004
-
Van Wart SA, Forrest A, Bhavnani SM, et al. Population pharmacokinetics of ceftaroline in healthy and renally impaired subjects. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1-004.
-
(2009)
-
-
Van Wart, S.A.1
Forrest, A.2
Bhavnani, S.M.3
-
48
-
-
84859579341
-
In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903M)
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1935.
-
Ge Y, Hubbel A. In vitro evaluation of plasma protein binding and metabolic stability of ceftaroline (PPI-0903M). Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1935.
-
(2006)
-
-
Ge, Y.1
Hubbel, A.2
-
49
-
-
84859619205
-
Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI)
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, San Francisco, Calif. Abstract A-1939.
-
Ge Y, Thye D, Liao S, Talbot GH. Pharmacokinetics (PK) of ceftaroline (PPI-0903) in subjects with mild or moderate renal impairment (RI). Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract A-1939.
-
(2006)
-
-
Ge, Y.1
Thye, D.2
Liao, S.3
Talbot, G.H.4
-
50
-
-
84859619206
-
An open-label pharmacokinetic (PK), safety, and tolerability study of single intravenous (IV) doses of ceftaroline (CPT) in subjects with normal renal function or severe renal impairment
-
Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1thomampersand
-
Riccobene T, Fang E, Thye D. An open-label pharmacokinetic (PK), safety, and tolerability study of single intravenous (IV) doses of ceftaroline (CPT) in subjects with normal renal function or severe renal impairment. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract A1-003.
-
-
-
Riccobene, T.1
Fang, E.2
Thye, D.3
-
51
-
-
79954568823
-
An open-label pharmacokinetic, safety and tolerability study of single-dose intravenous ceftaroline in subjects with end-stage renal disease on intermittent haemodialysis
-
Riccobene T., Jakate A., Rank D., Thye D. An open-label pharmacokinetic, safety and tolerability study of single-dose intravenous ceftaroline in subjects with end-stage renal disease on intermittent haemodialysis. Clin Microbiol Infect 2009, 15(Suppl s4):S407.
-
(2009)
Clin Microbiol Infect
, vol.15
, Issue.SUPPL. S4
-
-
Riccobene, T.1
Jakate, A.2
Rank, D.3
Thye, D.4
-
53
-
-
84859574080
-
Open-label pharmacokinetic, safety, and tolerability study of single intravenous doses of ceftaroline in healthy elderly and healthy young adult subjects
-
Abstract presented at: 2009 Midyear Clinical Meeting of the American Society of Health-System Pharmacists; December 6-10; Las Vegas, NV. Abstract 3-161.
-
Riccobene T, Jakate A, Rank D, Thye D. Open-label pharmacokinetic, safety, and tolerability study of single intravenous doses of ceftaroline in healthy elderly and healthy young adult subjects. Abstract presented at: 2009 Midyear Clinical Meeting of the American Society of Health-System Pharmacists; December 6-10, 2009; Las Vegas, NV. Abstract 3-161.
-
(2009)
-
-
Riccobene, T.1
Jakate, A.2
Rank, D.3
Thye, D.4
-
54
-
-
84859562509
-
A single- and multiple-dose study to determine the safety, tolerability, and pharmacokinetics (PK) of ceftaroline (CPT) administered by intramuscular (IM) injection to healthy subjects
-
Abstract presented at: 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/46th Annual Meeting of the Infectious Diseases Society of America; October 25-28; Washington, DC. Abstract A-1888.
-
Riccobene T, Fang E, Thye D. A single- and multiple-dose study to determine the safety, tolerability, and pharmacokinetics (PK) of ceftaroline (CPT) administered by intramuscular (IM) injection to healthy subjects. Abstract presented at: 48th Interscience Conference on Antimicrobial Agents and Chemotherapy/46th Annual Meeting of the Infectious Diseases Society of America; October 25-28, 2008; Washington, DC. Abstract A-1888.
-
(2008)
-
-
Riccobene, T.1
Fang, E.2
Thye, D.3
-
56
-
-
29444443515
-
Evaluation of PPI-090M (T91825)., a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests
-
Jones R.N., Fritsche T.R., Ge Y., et al. Evaluation of PPI-090M (T91825)., a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests. J Antimicrob Chemother 2005, 56:1047-1052.
-
(2005)
J Antimicrob Chemother
, vol.56
, pp. 1047-1052
-
-
Jones, R.N.1
Fritsche, T.R.2
Ge, Y.3
-
57
-
-
70350326281
-
In vitro activity of ceftaroline against methicillin-resistant Staphylococcus aureus and heterogeneous vancomycin-intermediate S. aureus in a hollow fiber model
-
Vidaillac C., Leonard S.N., Rybak M.J. In vitro activity of ceftaroline against methicillin-resistant Staphylococcus aureus and heterogeneous vancomycin-intermediate S. aureus in a hollow fiber model. Antimicrob Agents Chemother 2009, 53(11):4712-4717.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, Issue.11
, pp. 4712-4717
-
-
Vidaillac, C.1
Leonard, S.N.2
Rybak, M.J.3
-
58
-
-
3843081646
-
In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599
-
Iizawa Y., Nagai J., Ishikawa T., et al. In vitro antimicrobial activity of T-91825, a novel anti-MRSA cephalosporin, and in vivo anti-MRSA activity of its prodrug, TAK-599. J Infect Chemother 2004, 10:146-156.
-
(2004)
J Infect Chemother
, vol.10
, pp. 146-156
-
-
Iizawa, Y.1
Nagai, J.2
Ishikawa, T.3
-
59
-
-
84859619209
-
Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae
-
Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30; San Francisco, Calif. Abstract E-0121
-
Sader HS, Moet G, Fritsche TR, Jones RN. Evaluation of the bactericidal activity of the novel cephalosporin ceftaroline (PPI-0903M) compared to ceftriaxone against Streptococcus pneumoniae. Abstract presented at: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 27-30, 2006; San Francisco, Calif. Abstract E-0121.
-
(2006)
-
-
Sader, H.S.1
Moet, G.2
Fritsche, T.R.3
Jones, R.N.4
-
60
-
-
35948962693
-
In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model
-
Jacqueline C., Caillon J., Le Mabecque V., et al. In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model. Antimicrob Agents Chemother 2007, 51:3397-3400.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3397-3400
-
-
Jacqueline, C.1
Caillon, J.2
Le Mabecque, V.3
-
61
-
-
70349349051
-
Postantibiotic effect of ceftaroline against gram-positive organisms
-
Pankuch G.A., Appelbaum P.C. Postantibiotic effect of ceftaroline against gram-positive organisms. Antimicrob Agents Chemother 2009, 53:4537-4539.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4537-4539
-
-
Pankuch, G.A.1
Appelbaum, P.C.2
-
62
-
-
33645766499
-
Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target
-
Andes D., Craig W.A. Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target. Antimicrob Agents Chemother 2006, 50:1376-1383.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1376-1383
-
-
Andes, D.1
Craig, W.A.2
-
63
-
-
77951764966
-
In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates
-
Vidaillac C., Leonard S.N., Rybak M.J. In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates. Int J Antimicrob Agents 2010, 35:527-530.
-
(2010)
Int J Antimicrob Agents
, vol.35
, pp. 527-530
-
-
Vidaillac, C.1
Leonard, S.N.2
Rybak, M.J.3
-
64
-
-
4444347175
-
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor
-
Bonnefoy A., Dupuis-Hamelin C., Steier V., et al. In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor. J Antimicrob Chemother 2004, 54:410-417.
-
(2004)
J Antimicrob Chemother
, vol.54
, pp. 410-417
-
-
Bonnefoy, A.1
Dupuis-Hamelin, C.2
Steier, V.3
-
65
-
-
84859619208
-
Comparison of the antibacterial effects of two dosing regimens of ceftaroline in combination with NXL104 against Enterobacteriaceae
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-1377
-
Bowker K, Noel A, Elliott H, et al. Comparison of the antibacterial effects of two dosing regimens of ceftaroline in combination with NXL104 against Enterobacteriaceae. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1377.
-
(2010)
-
-
Bowker, K.1
Noel, A.2
Elliott, H.3
-
66
-
-
84859579343
-
Pharmacodynamics (PD) of ceftaroline (CPT) fosamil plus 1:1 and 2:1 ratios of NXL104 (NXL) against Enterobacteriaceae (ENT) containing ESBLs and carbapenemases (KPCs) in neutropenic mouse thighs
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-138
-
Craig WA, Andes DR. Pharmacodynamics (PD) of ceftaroline (CPT) fosamil plus 1:1 and 2:1 ratios of NXL104 (NXL) against Enterobacteriaceae (ENT) containing ESBLs and carbapenemases (KPCs) in neutropenic mouse thighs. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1387.
-
(2010)
-
-
Craig, W.A.1
Andes, D.R.2
-
67
-
-
84859579342
-
In vivo antibacterial efficacy of ceftaroline (CPT) combined with the beta-lactamase inhibitor NXL104 in a murine septicemia model
-
Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; San Francisco, Calif. Abstract B-1339a.
-
Levasseur P, Girard A-M, Williams G, et al. In vivo antibacterial efficacy of ceftaroline (CPT) combined with the beta-lactamase inhibitor NXL104 in a murine septicemia model. Abstract presented at: 49th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2009; San Francisco, Calif. Abstract B-1339a.
-
(2009)
-
-
Levasseur, P.1
Girard, A.-M.2
Williams, G.3
-
68
-
-
79959280244
-
In vivo efficacy of a human-simulated regimen of ceftaroline fosamil combined with NXL104 (CXL) against ESBL- and non-ESBL-producing Enterobacteriaceae
-
Wiskirchen D.E., Crandon J.L., Furtado G.H., et al. In vivo efficacy of a human-simulated regimen of ceftaroline fosamil combined with NXL104 (CXL) against ESBL- and non-ESBL-producing Enterobacteriaceae. Antimicrob Agents Chemother 2011, 55:3220-3225.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 3220-3225
-
-
Wiskirchen, D.E.1
Crandon, J.L.2
Furtado, G.H.3
-
69
-
-
84859562510
-
Comparative time-kill analysis of ceftaroline (CPT) with and without NXL104 (NXL) against anaerobes
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract A1-1396
-
Credito K, Ednie LM, Appelbaum PC. Comparative time-kill analysis of ceftaroline (CPT) with and without NXL104 (NXL) against anaerobes. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract A1-1396.
-
(2010)
-
-
Credito, K.1
Ednie, L.M.2
Appelbaum, P.C.3
-
70
-
-
79954622500
-
FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
-
Low D.E., File T.M., Eckburg P.B., et al. FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii33-iii44.
-
(2011)
J Antimicrob Chemother
, vol.66
-
-
Low, D.E.1
File, T.M.2
Eckburg, P.B.3
-
72
-
-
84859582777
-
Multistep resistance development studies of ceftaroline (CPT) with Streptococcus pneumoniae, Streptococcus pyogenes, staphylococci, and enterococci
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, Boston MA. Abstract E-813
-
Clark C, Kosowska-Shick K, McGhee P, Appelbaum P. Multistep resistance development studies of ceftaroline (CPT) with Streptococcus pneumoniae, Streptococcus pyogenes, staphylococci, and enterococci. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston MA. Abstract E-813.
-
(2010)
-
-
Clark, C.1
Kosowska-Shick, K.2
McGhee, P.3
Appelbaum, P.4
-
73
-
-
84859619207
-
Multistep resistance development studies of ceftaroline (CPT) with Haemophilus influenzae and Moraxella catarrhalis
-
Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15; Boston, MA. Abstract E-814
-
Clark C, Kosowska-Shick K, McGhee P, Appelbaum P. Multistep resistance development studies of ceftaroline (CPT) with Haemophilus influenzae and Moraxella catarrhalis. Abstract presented at: 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 12-15, 2010; Boston, MA. Abstract E-814.
-
(2010)
-
-
Clark, C.1
Kosowska-Shick, K.2
McGhee, P.3
Appelbaum, P.4
-
74
-
-
84859577671
-
Ceftaroline vs ceftriaxone in a highly penicillin-resistant pneumococcal pneumonia model
-
Croisier-Bertin D., Piroth L., Charles P.E., et al. Ceftaroline vs ceftriaxone in a highly penicillin-resistant pneumococcal pneumonia model. Clin Microbiol Infect 2009, 15(Suppl s4):S81.
-
(2009)
Clin Microbiol Infect
, vol.15
, Issue.SUPPL. S4
-
-
Croisier-Bertin, D.1
Piroth, L.2
Charles, P.E.3
-
75
-
-
84859579344
-
Ceftaroline is superior to cefepime against a Klebsiella pneumoniae strain an experimental rabbit meningitis model
-
Cottagnoud P., Stucki A., Accosta F., et al. Ceftaroline is superior to cefepime against a Klebsiella pneumoniae strain an experimental rabbit meningitis model. Clin Microbiol Infect 2010, 16(Suppl s2):S4565.
-
(2010)
Clin Microbiol Infect
, vol.16
, Issue.SUPPL. S2
-
-
Cottagnoud, P.1
Stucki, A.2
Accosta, F.3
-
76
-
-
79952781069
-
Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus
-
Jacqueline C., Amador G., Batard E., et al. Comparison of ceftaroline fosamil, daptomycin and tigecycline in an experimental rabbit endocarditis model caused by methicillin-susceptible, methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus. J Antimicrob Chemother 2011, 66:863-866.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 863-866
-
-
Jacqueline, C.1
Amador, G.2
Batard, E.3
-
77
-
-
77957241721
-
Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model
-
Jacqueline C., Caillon J., Batard E., et al. Evaluation of the in vivo efficacy of intramuscularly administered ceftaroline fosamil, a novel cephalosporin, against a methicillin-resistant Staphylococcus aureus strain in a rabbit endocarditis model. J Antimicrob Chemother 2010, 65:2264-2265.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 2264-2265
-
-
Jacqueline, C.1
Caillon, J.2
Batard, E.3
-
78
-
-
77954724135
-
Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis
-
Jacqueline C., Amador G., Caillon J., et al. Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis. J Antimicrob Chemother 2010, 65:1749-1752.
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 1749-1752
-
-
Jacqueline, C.1
Amador, G.2
Caillon, J.3
-
79
-
-
34948854764
-
Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections
-
Talbot G.H., Thye D., Das A., Ge Y. Phase 2 study of ceftaroline versus standard therapy in treatment of complicated skin and skin structure infections. Antimicrob Agents Chemother 2007, 51:3612-3616.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3612-3616
-
-
Talbot, G.H.1
Thye, D.2
Das, A.3
Ge, Y.4
-
80
-
-
78649485323
-
CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
-
Corey G.R., Wilcox M.H., Talbot G.H., et al. CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv41-iv51.
-
(2010)
J Antimicrob Chemother
, vol.65
-
-
Corey, G.R.1
Wilcox, M.H.2
Talbot, G.H.3
-
81
-
-
78649489951
-
CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
-
Wilcox M.H., Corey G.R., Talbot G.H., et al. CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv53-iv 65.
-
(2010)
J Antimicrob Chemother
, vol.65
-
-
Wilcox, M.H.1
Corey, G.R.2
Talbot, G.H.3
-
82
-
-
79954622500
-
FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
-
File T.M., Low D.E., Eckburg P.B., et al. FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii19-iii32.
-
(2011)
J Antimicrob Chemother
, vol.66
-
-
File, T.M.1
Low, D.E.2
Eckburg, P.B.3
-
83
-
-
77955957827
-
Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection
-
Corey G.R., Wilcox M., Talbot G.H., et al. Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection. Clin Infect Dis 2010, 51:641-650.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 641-650
-
-
Corey, G.R.1
Wilcox, M.2
Talbot, G.H.3
-
84
-
-
78649873377
-
Integrated analysis of FOCUS 1 and FOCUS 2: randomized, double-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia
-
File T.M., Low D.E., Eckburg P.B., et al. Integrated analysis of FOCUS 1 and FOCUS 2: randomized, double-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia. Clin Infect Dis 2010, 51:1395-1405.
-
(2010)
Clin Infect Dis
, vol.51
, pp. 1395-1405
-
-
File, T.M.1
Low, D.E.2
Eckburg, P.B.3
-
86
-
-
84859582778
-
-
ClinicalTrials.gov, Accessed April 30, 2011
-
A single-centre, randomised, double-blind, placebo-controlled, four way crossover phase I study to investigate the effect on QT/QTc interval of ceftazidime NXL 104 or ceftaroline fosamil NXL104, compared with placebo, using moxifloxacin (Avelox®) as a positive control, in healthy male volunteers ClinicalTrials.gov, Accessed April 30, 2011. http://clinicaltrials.gov/ct2/show/NCT01290900?term=ceftaroline&rank=4.
-
A single-centre, randomised, double-blind, placebo-controlled, four way crossover phase I study to investigate the effect on QT/QTc interval of ceftazidime NXL 104 or ceftaroline fosamil NXL104, compared with placebo, using moxifloxacin (Avelox®) as a positive control, in healthy male volunteers
-
-
-
88
-
-
79954622204
-
Review of ceftaroline fosamil microbiology: integrated FOCUS studies
-
Critchley I.A., Eckburg P.B., Jandourek A., et al. Review of ceftaroline fosamil microbiology: integrated FOCUS studies. J Antimicrob Chemother 2011, 66:iii45-iii51.
-
(2011)
J Antimicrob Chemother
, vol.66
-
-
Critchley, I.A.1
Eckburg, P.B.2
Jandourek, A.3
-
89
-
-
78649453055
-
Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections
-
Corrado M.L. Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections. J Antimicrob Chemother 2010, 65:iv67-iv 71.
-
(2010)
J Antimicrob Chemother
, vol.65
-
-
Corrado, M.L.1
-
90
-
-
79954568574
-
Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia
-
Rank D.R., Friedland H.D., Laudano J.B. Integrated safety summary of FOCUS 1 and FOCUS 2 trials: Phase III randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with community-acquired pneumonia. J Antimicrob Chemother 2011, 66:iii53-iii59.
-
(2011)
J Antimicrob Chemother
, vol.66
-
-
Rank, D.R.1
Friedland, H.D.2
Laudano, J.B.3
-
91
-
-
84859564541
-
-
Thomson Medical Economics, Montvale, NJ
-
2011 Drug Topics Red Book 2011, Thomson Medical Economics, Montvale, NJ.
-
(2011)
2011 Drug Topics Red Book
-
-
-
92
-
-
62449183879
-
Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists
-
Rybak M., Lomaestro B., Rotschafer J.C., et al. Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm 2009, 66:82-98.
-
(2009)
Am J Health Syst Pharm
, vol.66
, pp. 82-98
-
-
Rybak, M.1
Lomaestro, B.2
Rotschafer, J.C.3
|