Celecoxib attenuates systemic lipopolysaccharide-induced brain inflammation and white matter injury in the neonatal rats

Neuroscience

Volumn 240, Issue , 2013, Pages 27-38

  Fan, L W ^a   Kaizaki, A ^a,b   Tien, L T ^c   Pang, Y ^a   Tanaka, S ^b   Numazawa, S ^b   Bhatt, A J ^a   Cai, Z ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b SHOWA UNIVERSITY   (Japan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Astrocyte; Celecoxib; Cyclooxygenase 2; Lipopolysaccharide; Microglia; Oligodendrocyte

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BEHAVIOR DISORDER; BODY WEIGHT; BRAIN INJURY; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; CYTOKINE RESPONSE; DRUG MECHANISM; ENCEPHALITIS; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOREACTIVITY; MICROGLIA; NEUROPROTECTION; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; TASK PERFORMANCE; WHITE MATTER INJURY;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BRAIN; CALCIUM-BINDING PROTEINS; CELL DEATH; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; ENCEPHALITIS; FEMALE; FORELIMB; GLIAL FIBRILLARY ACIDIC PROTEIN; IN SITU NICK-END LABELING; INTERLEUKIN-1BETA; LEUKOENCEPHALOPATHIES; LIPOPOLYSACCHARIDES; MALE; MICROFILAMENT PROTEINS; MUSCLE STRENGTH; O ANTIGENS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PREGNANCY; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84875802587     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.02.041     Document Type: Article

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