A zebrafish model of PINK1 deficiency reveals key pathway dysfunction including HIF signaling

Neurobiology of Disease

Volumn 54, Issue , 2013, Pages 127-138

  Priyadarshini, M ^a   Tuimala, J ^b,c   Chen, Y C ^a   Panula, P ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b IT Center for Science   (Finland)

^c Finnish Red Cross   (Finland)

Author keywords

HIF; Notch1a; Parkinson's disease; PINK1; ROS; Vegf

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE; RETINOIC ACID RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ANIMAL EXPERIMENT; ARTICLE; ATP1A2A GENE; BIOGENESIS; CATALASE GENE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; EMBRYO; ERYTHROPOIESIS; FECH GENE; GENE; GENE FUNCTION; GENE SILENCING; HEART DISEASE; HIGH THROUGHPUT SEQUENCING; HYPOXIA INDUCIBLE FACTOR 1ALPHA GENE; LARVA; MICROARRAY ANALYSIS; MITOCHONDRION; NONHUMAN; NOTCH1A GENE; PAX2A GENE; PINK1 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SOD3 GENE; UPREGULATION; WILD TYPE; ZEBRA FISH;

ANIMALS; DISEASE MODELS, ANIMAL; HYPOXIA-INDUCIBLE FACTOR 1; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARKINSONIAN DISORDERS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTOME; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84875769477     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.02.002     Document Type: Article

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