Submicron scale-structured hydrophilic titanium surfaces promote early osteogenic gene response for cell adhesion and cell differentiation

Clinical Implant Dentistry and Related Research

Volumn 15, Issue 2, 2013, Pages 166-175

  Klein, Marcus Oliver ^a   Bijelic, Ana ^a   Ziebart, Thomas ^a   Koch, Felix ^a   Kämmerer, Peer W ^a   Wieland, Marco ^a   Konerding, Moritz A ^b   Al Nawas, Bilal ^c  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b MyoPowers Medical Technologies SA   (Switzerland)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Cell adhesion; Cell differentiation; Integrins; Osteocalcin; Osteogenic cell proliferation; Runx 2; Surface hydrophilicity; Titanium surface modifications

Indexed keywords

ALKALINE PHOSPHATASE; BETA1 INTEGRIN; CD51 ANTIGEN; COLLAGEN TYPE 1; DENTAL MATERIAL; OSTEOCALCIN; POLYSTYRENE DERIVATIVE; RUNX2 PROTEIN, HUMAN; TITANIUM; TITANIUM DIOXIDE; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; BONE DEVELOPMENT; CELL ADHESION; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CHEMICAL PHENOMENA; CHEMISTRY; CULTURE TECHNIQUE; DENTAL ACID ETCHING; DENTAL ETCHING; GENETICS; HUMAN; METHODOLOGY; OSTEOBLAST; PHENOTYPE; PHYSIOLOGY; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SURFACE PROPERTY; TIME;

ACID ETCHING, DENTAL; ALKALINE PHOSPHATASE; ANTIGENS, CD29; CELL ADHESION; CELL COUNT; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CELLS, CULTURED; COLLAGEN TYPE I; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DENTAL ETCHING; DENTAL MATERIALS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTEGRIN ALPHAV; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; PHENOTYPE; POLYSTYRENES; SURFACE PROPERTIES; TIME FACTORS; TITANIUM;

EID: 84875764585     PISSN: 15230899     EISSN: 17088208     Source Type: Journal    
DOI: 10.1111/j.1708-8208.2011.00339.x     Document Type: Article

References (44)

1. Boyan BD, Lossdorfer S, Wang L, Zhao G, Lohmann CH, Cochran DL, Schwartz Z. Osteoblasts generate an osteogenic microenvironment when grown on surfaces with rough microtopographies. Eur Cell Mater 2003; 6:22-27.
2. Puleo DA, Nanci A. Understanding and controlling the bone-implant interface. Biomaterials 1999; 20:2311-2321.
3. Zhao G, Raines AL, Wieland M, Schwartz Z, Boyan BD. Requirement for both micron- and submicron scale structure for synergistic responses of osteoblasts to substrate surface energy and topography. Biomaterials 2007; 28:2821-2829.
4. Schlegel KA, Thorwarth M, Plesinac A, Wiltfang J, Rupprecht S. Expression of bone matrix proteins during the osseus healing of topical conditioned implants: an experimental study. Clin Oral Implants Res 2006; 17:666-672.
5. Zhao G, Zinger O, Schwartz Z, Wieland M, Landolt D, Boyan BD. Osteoblast-like cells are sensitive to submicron-scale surface structure. Clin Oral Implants Res 2006; 17:258-264.
6. Zinger O, Zhao G, Schwartz Z, Simpson J, Wieland M, Landolt D, Boyan B. Differential regulation of osteoblasts by substrate microstructural features. Biomaterials 2005; 26:1837-1847.
7. Zhao G, Schwartz Z, Wieland M, Rupp F, Geis-Gerstorfer J, Cochran DL, Boyan BD. High surface energy enhances cell response to titanium substrate microstructure. J Biomed Mater Res A 2005; 74:49-58.
8. Scheideler L, Rupp F, Wieland M, Geis-Gerstorfer J. Storage conditions of titanium implants influence molecular and cellular interactions. Int Assoc Dent Res (IADR) 83rd General Session, Baltimore, MD, March 9-12, 2005. J Dent Res 2005; 84(Spec Iss A). Abstract 870.
9. Buser D, Broggini N, Wieland M, etal. Enhanced bone apposition to a chemically modified SLA titanium surface. J Dent Res 2004; 83:529-533.
10. Kaback LA, Soung Do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H. Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. J Cell Physiol 2008; 214:173-182.
11. Schwarz F, Herten M, Wieland M, Dard M, Becker J. [Chemically modified, ultra-hydrophilic titanium implant surfaces]. Mund Kiefer Gesichtschir 2007; 11:11-17.
12. Ferguson SJ, Broggini N, Wieland M, etal. Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface. J Biomed Mater Res A 2006; 78:291-297.
13. Oates TW, Valderrama P, Bischof M, etal. Enhanced implant stability with a chemically modified SLA surface: a randomized pilot study. Int J Oral Maxillofac Implants 2007; 22:755-760.
14. Keselowsky BG, Wang L, Schwartz Z, Garcia AJ, Boyan BD. Integrin alpha(5) controls osteoblastic proliferation and differentiation responses to titanium substrates presenting different roughness characteristics in a roughness independent manner. J Biomed Mater Res A 2007; 80:700-710.
15. Anselme K. Osteoblast adhesion on biomaterials. Biomaterials 2000; 21:667-681.
16. El-Ghannam AR, Ducheyne P, Risbud M, etal. Model surfaces engineered with nanoscale roughness and RGD tripeptides promote osteoblast activity. J Biomed Mater Res A 2004; 68:615-627.
17. Aubin JE. Advances in the osteoblast lineage. Biochem Cell Biol 1998; 76:899-910.
18. Malaval L, Liu F, Roche P, Aubin JE. Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro. J Cell Biochem 1999; 74:616-627.
19. Liu F, Malaval L, Aubin JE. Global amplification polymerase chain reaction reveals novel transitional stages during osteoprogenitor differentiation. J Cell Sci 2003; 116(Pt 9): 1787-1796.
20. Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997; 89:747-754.
21. Qi H, Aguiar DJ, Williams SM, La Pean A, Pan W, Verfaillie CM. Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells. Proc Natl Acad Sci U S A 2003; 100:3305-3310.
22. Stein GS, Lian JB, Van Wijnen AJ, etal. Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression. Oncogene 2004; 23:4315-4329.
23. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29:e45.
24. Suzuki T, Higgins PJ, Crawford DR. Control selection for RNA quantitation. Biotechniques 2000; 29:332-337.
25. Thellin O, Zorzi W, Lakaye B, etal. Housekeeping genes as internal standards: use and limits. J Biotechnol 1999; 75:291-295.
26. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3:RESEARCH0034.
27. Reynolds ES. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J Cell Biol 1963; 17:208-212.
28. Jemt T, Chai J, Harnett J, etal. A 5-year prospective multicenter follow-up report on overdentures supported by osseointegrated implants. Int J Oral Maxillofac Implants 1996; 11:291-298.
29. Nkenke E, Fenner M. Indications for immediate loading of implants and implant success. Clin Oral Implants Res 2006; 17(Suppl 2):19-34.
30. De Rouck T, Collys K, Cosyn J. Single-tooth replacement in the anterior maxilla by means of immediate implantation and provisionalization: a review. Int J Oral Maxillofac Implants 2008; 23:897-904.
31. Aghaloo TL, Moy PK. Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement? Int J Oral Maxillofac Implants 2007; 22 (Suppl):49-70.
32. Simeone A, Acampora D, Pannese M, etal. Cloning and characterization of two members of the vertebrate Dlx gene family. Proc Natl Acad Sci U S A 1994; 91:2250-2254.
33. Klein MO, Grötz KA, Walter C, Wegener J, Wagner W, Al-Nawas B. Functional rehabilitation of mandibular continuity defects using autologous bone and dental implants - prognostic value of bone origin, radiation therapy and implant dimensions. Eur Surg Res 2009; 43:269-275.
34. Madrid C, Sanz M. What impact do systemically administrated bisphosphonates have on oral implant therapy? A systematic review. Clin Oral Implants Res 2009; 20:87-95.
35. Laize V, Martel P, Viegas CS, Price PA, Cancela ML. Evolution of matrix and bone gamma-carboxyglutamic acid proteins in vertebrates. J Biol Chem 2005; 280:26659-26668.
36. Kinoshita S, Finnegan M, Bucholz RW, Mizuno K. Three-dimensional collagen gel culture promotes osteoblastic phenotype in bone marrow derived cells. Kobe J Med Sci 1999; 45:201-211.
37. Anderson HC, Sipe JB, Hessle L, Dhanyamraju R, Atti E, Camacho NP, Millan JL. Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice. Am J Pathol 2004; 164:841-847.
38. Hessle L, Johnson KA, Anderson HC, etal. Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci U S A 2002; 99:9445-9449.
39. Lian JB, Stein GS, Stein JL, van Wijnen AJ. Osteocalcin gene promoter: unlocking the secrets for regulation of osteoblast growth and differentiation. J Cell Biochem Suppl 1998; 30-31:62-72.
40. Lian JB, Javed A, Zaidi SK, etal. Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors. Crit Rev Eukaryot Gene Expr 2004; 14:1-41.
41. Knabe C, Howlett CR, Klar F, Zreiqat H. The effect of different titanium and hydroxyapatite-coated dental implant surfaces on phenotypic expression of human bone-derived cells. J Biomed Mater Res A 2004; 71:98-107.
42. Omar O, Lenneras M, Svensson S, etal. Integrin and chemokine receptor gene expression in implant-adherent cells during early osseointegration. J Mater Sci Mater Med 2010; 21:969-980.
43. Omar O, Svensson S, Zoric N, etal. In vivo gene expression in response to anodically oxidized versus machined titanium implants. J Biomed Mater Res A 2010; 92:1552-1566.
44. Aubin JE. Regulation of osteoblast formation and function. Rev Endocr Metab Disord 2001; 2:81-94.