Integrin and chemokine receptor gene expression in implant-adherent cells during early osseointegration

Journal of Materials Science: Materials in Medicine

Volumn 21, Issue 3, 2010, Pages 969-980

  Omar, Omar ^a,e   Lennerås, Maria ^b,e   Svensson, Sara ^a,e   Suska, Felicia ^a,e   Emanuelsson, Lena ^a,e   Hall, Jan ^c   Nannmark, Ulf ^d   Thomsen, Peter ^a,e  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b TATAA Biocenter AB   (Sweden)

^c Nobel Biocare AB   (Sweden)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

^e BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADHERENT CELLS; CELL TYPES; CHEMOKINE RECEPTORS; CHEMOKINES; IMMUNOHISTOCHEMISTRY; IMPLANT SURFACE; IN-VIVO; INFLAMMATORY CYTOKINES; INTEGRINS; INTERLEUKIN-1; MACHINED SURFACE; MATERIAL SURFACE; OSSEOINTEGRATION; OXIDIZED SURFACES; QUANTITATIVE POLYMERASE CHAIN REACTION; RAT TIBIA; REGENERATIVE PROCESS; RIBOSOMAL RNA; SMALL SUBUNITS; TITANIUM IMPLANTS; TUMOR NECROSIS FACTORS;

ADHESION; EMPLOYMENT; GLYCOPROTEINS; POLYMERASE CHAIN REACTION; RNA; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTIES; TITANIUM;

GENE EXPRESSION;

ALPHA5 INTEGRIN; BETA1 INTEGRIN; BETA2 INTEGRIN; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; INTEGRIN; INTERLEUKIN 1BETA; RNA 18S; TITANIUM; TUMOR NECROSIS FACTOR ALPHA; CXCR4 PROTEIN, RAT;

ADHESION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BONE REGENERATION; CELL ADHESION; CELL TYPE; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMPLANT; IN VIVO STUDY; INFLAMMATION; MORPHOLOGY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR GENE; REGENERATION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TIBIA; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; PROCEDURES; PROSTHESES AND ORTHOSES; SPRAGUE DAWLEY RAT;

ANIMALS; CELL ADHESION; CHEMOKINES; FEMALE; GENE EXPRESSION REGULATION; INTEGRINS; MICROSCOPY, ELECTRON, SCANNING; OSSEOINTEGRATION; PROSTHESES AND IMPLANTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; TIBIA; TITANIUM; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 77951255060     PISSN: 09574530     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10856-009-3915-x     Document Type: Conference Paper

References (75)

1. Anderson J. Inflammation, wound healing and the foreign body response. In: Ratner B, Hoffman A, Schoen F, Lemons J, editors. Biomaterials science, an introduction to materials in medicine. San Diego: Academic Press; 1996. p. 165-73.
2. Thomsen P, Ericson L. Inflammatory cell response to bone implant surfaces. In: Davies JE, editor. The bone-biomaterial interface. Toronto: University of Toronto Press; 1991. p. 153-69.
3. A Abron M Hopfensperger J Thompson LF Cooper 2001 Evaluation of a predictive model for implant surface topography effects on early osseointegration in the rat tibia model J Prosthet Dent 85 40 46 10.1067/mpr.2001.112415 1:STN:280:DC%2BD3M3jsVChtw%3D%3D 11174677 (Pubitemid 33660928)
4. CM Clokie H Warshawsky 1995 Morphologic and radioautographic studies of bone formation in relation to titanium implants using the rat tibia as a model Int J Oral Maxillofac Implants 10 155 165 1:STN:280:DyaK2M3mtlSqtw%3D%3D 7744434
5. T Masuda GE Salvi S Offenbacher DA Felton LF Cooper 1997 Cell and matrix reactions at titanium implants in surgically prepared rat tibiae Int J Oral Maxillofac Implants 12 472 485 1:STN:280:DyaK2svhvFGluw%3D%3D 9274076 (Pubitemid 127500400)
6. Omar O, Svensson S, Zoric N, Lennerås M, Suska F, Wigren S, et al. In vivo gene expression in response to anodically oxidized versus machined titanium implants. J Biomed Mater Res A. 2009. [Epub ahead of print]. doi: 10.1002/jbm.a.32475.
7. DJ Campbell CH Kim EC Butcher 2003 Chemokines in the systemic organization of immunity Immunol Rev 195 58 71 10.1034/j.1600-065X.2003.00067.x 1:CAS:528:DC%2BD3sXotFyrt7s%3D 12969310 (Pubitemid 37153453)
8. H Amano K Morimoto M Senba H Wang Y Ishida A Kumatori, et al. 2004 Essential contribution of monocyte chemoattractant protein-1/C-C chemokine ligand-2 to resolution and repair processes in acute bacterial pneumonia J Immunol 172 398 409 1:CAS:528:DC%2BD3sXpvFehurk%3D 14688348 (Pubitemid 38020494)
9. J Ringe S Strassburg K Neumann M Endres M Notter GR Burmester, et al. 2007 Towards in situ tissue repair: human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2 J Cell Biochem 101 135 146 10.1002/jcb.21172 1:CAS:528:DC%2BD2sXkvFeku78%3D 17295203 (Pubitemid 46652579)
10. MR Hoenig C Bianchi FW Sellke 2008 Hypoxia inducible factor-1 alpha, endothelial progenitor cells, monocytes, cardiovascular risk, wound healing, cobalt and hydralazine: a unifying hypothesis Curr Drug Targets 9 422 435 10.2174/138945008784221215 1:CAS:528:DC%2BD1cXkvFelsbo%3D 18473772 (Pubitemid 352025218)
11. TS Liao MB Yurgelun SS Chang HZ Zhang K Murakami TA Blaine, et al. 2005 Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone J Orthop Res 23 203 209 10.1016/j.orthres.2004.06.018 15607894 (Pubitemid 40045096)
12. SC Pitchford RC Furze CP Jones AM Wengner SM Rankin 2009 Differential mobilization of subsets of progenitor cells from the bone marrow Cell Stem Cell 4 62 72 10.1016/j.stem.2008.10.017 1:CAS:528:DC%2BD1MXhtVSks70%3D 19128793
13. A Dar P Goichberg V Shinder A Kalinkovich O Kollet N Netzer, et al. 2005 Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells Nat Immunol 6 1038 1046 10.1038/ni1251 1:CAS:528:DC%2BD2MXhtVajsL7P 16170318 (Pubitemid 41486189)
14. JF Ji BP He ST Dheen SS Tay 2004 Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury Stem Cells 22 415 427 10.1634/stemcells.22-3-415 1:CAS:528:DC%2BD2cXlsFCnsr0%3D 15153618
15. T Kitaori H Ito EM Schwarz R Tsutsumi H Yoshitomi S Oishi, et al. 2009 Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model Arthritis Rheum 60 813 823 10.1002/art.24330 1:CAS:528: DC%2BD1MXktVGmsb0%3D 19248097
16. RF Wynn CA Hart C Corradi-Perini L O'Neill CA Evans JE Wraith, et al. 2004 A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow Blood 104 2643 2645 10.1182/blood-2004-02-0526 1:CAS:528:DC%2BD2cXpslKjs7o%3D 15251986 (Pubitemid 39434942)
17. DJ Ceradini AR Kulkarni MJ Callaghan OM Tepper N Bastidas ME Kleinman, et al. 2004 Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1 Nat Med 10 858 864 10.1038/nm1075 1:CAS:528: DC%2BD2cXmtFWrtr0%3D 15235597 (Pubitemid 39070860)
18. M Baggiolini B Dewald B Moser 1997 Human chemokines: an update Annu Rev Immunol 15 675 705 10.1146/annurev.immunol.15.1.675 1:CAS:528:DyaK2sXisVCmtLY%3D 9143704 (Pubitemid 27169296)
19. DT Graves Y Jiang 1995 Chemokines, a family of chemotactic cytokines Crit Rev Oral Biol Med 6 109 118 10.1177/10454411950060020101 1:STN:280: DyaK28%2FlsF2htg%3D%3D 7548618
20. DT Graves Y Jiang AJ Valente 1999 The expression of monocyte chemoattractant protein-1 and other chemokines by osteoblasts Front Biosci 4 D571 D580 10.2741/Graves 1:CAS:528:DyaK1MXltFKlsbs%3D 10393126
21. P Rahimi CY Wang P Stashenko SK Lee JA Lorenzo DT Graves 1995 Monocyte chemoattractant protein-1 expression and monocyte recruitment in osseous inflammation in the mouse Endocrinology 136 2752 2759 10.1210/en.136.6.2752 1:CAS:528:DyaK2MXlslGgurc%3D 7750500
22. Y Nakashima DH Sun MC Trindade LE Chun Y Song SB Goodman, et al. 1999 Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles J Bone Joint Surg Br 81 155 162 10.1302/0301-620X.81B1.8884 1:STN:280:DyaK1M7msFektw%3D%3D 10068024 (Pubitemid 29043430)
23. EA Fritz TT Glant C Vermes JJ Jacobs KA Roebuck 2002 Titanium particles induce the immediate early stress responsive chemokines IL-8 and MCP-1 in osteoblasts J Orthop Res 20 490 498 10.1016/S0736-0266(01)00154-1 1:CAS:528:DC%2BD38XksVCru7w%3D 12038622 (Pubitemid 34461007)
24. V Videm E Strand 2004 Changes in neutrophil surface-receptor expression after stimulation with FMLP, endotoxin, interleukin-8 and activated complement compared to degranulation Scand J Immunol 59 25 33 10.1111/j.0300-9475.2004. 01351.x 1:CAS:528:DC%2BD2cXhvFajsL8%3D 14723618 (Pubitemid 38186836)
25. PM Murphy M Baggiolini IF Charo CA Hebert R Horuk K Matsushima, et al. 2000 International union of pharmacology. XXII. Nomenclature for chemokine receptors Pharmacol Rev 52 145 176 1:CAS:528:DC%2BD3cXjvVWgtbs%3D 10699158 (Pubitemid 30127598)
26. Boyan B, Dean D, Lohmann C, Cochran D, Sylvia V, Schwartz Z. The titanium-bone cell interface in vitro: the role of the surface in promoting osteointegration. In: Brunette DM, Tengvall P, Textor M, Thomsen P, editors. Titanium in medicine. New York: Springer; 2001. p. 561-85.
27. RK Sinha RS Tuan 1996 Regulation of human osteoblast integrin expression by orthopedic implant materials Bone 18 451 457 10.1016/8756-3282(96)00044-0 1:STN:280:DyaK28zhvFWrtw%3D%3D 8739903 (Pubitemid 26152308)
28. A Diener B Nebe F Luthen P Becker U Beck HG Neumann, et al. 2005 Control of focal adhesion dynamics by material surface characteristics Biomaterials 26 383 392 10.1016/j.biomaterials.2004.02.038 1:CAS:528:DC%2BD2cXlvFarsrw%3D 15275812 (Pubitemid 38951105)
29. M Stewart M Thiel N Hogg 1995 Leukocyte integrins Curr Opin Cell Biol 7 690 696 10.1016/0955-0674(95)80111-1 1:CAS:528:DyaK2MXosVKns74%3D 8573344
30. MA Arnaout 1990 Leukocyte adhesion molecules deficiency: its structural basis, pathophysiology and implications for modulating the inflammatory response Immunol Rev 114 145 180 10.1111/j.1600-065X.1990.tb00564.x 1:CAS:528: DyaK3cXltFehurs%3D 1973407
31. H Hayashi K Nakahama T Sato T Tuchiya Y Asakawa T Maemura, et al. 2008 The role of Mac-1 (CD11b/CD18) in osteoclast differentiation induced by receptor activator of nuclear factor-kappaB ligand FEBS Lett 582 3243 3248 10.1016/j.febslet.2008.08.023 1:CAS:528:DC%2BD1cXhtFart7nF 18775427
32. A Krause EA Cowles G Gronowicz 2000 Integrin-mediated signaling in osteoblasts on titanium implant materials J Biomed Mater Res 52 738 747 10.1002/1097-4636(20001215)52:4<738::AID-JBM19>3.0.CO;2-F 1:CAS:528:DC%2BD3cXnt1Clurs%3D 11033557
33. M Rouahi E Champion P Hardouin K Anselme 2006 Quantitative kinetic analysis of gene expression during human osteoblastic adhesion on orthopaedic materials Biomaterials 27 2829 2844 10.1016/j.biomaterials.2006.01.001 1:CAS:528:DC%2BD28XhtVans7Y%3D 16427124 (Pubitemid 43165752)
34. PJ ter Brugge JA Jansen 2002 Initial interaction of rat bone marrow cells with non-coated and calcium phosphate coated titanium substrates Biomaterials 23 3269 3277 10.1016/S0142-9612(02)00085-6 12102198 (Pubitemid 34522139)
35. MA Woodruff P Jones D Farrar DM Grant CA Scotchford 2007 Human osteoblast cell spreading and vinculin expression upon biomaterial surfaces J Mol Histol 38 491 499 10.1007/s10735-007-9142-1 1:CAS:528:DC%2BD2sXht1Glu7nI 17849222 (Pubitemid 350056781)
36. Omar O, Suska F, Lenneras M, Zoric N, Svensson S, Hall J, et al. The influence of bone type on the gene expression in normal bone and at the bone-implant interface: experiments in animal model. Clin Implant Dent Relat Res. 2009.
37. S Rozen H Skaletsky 2000 Primer3 on the WWW for general users and for biologist programmers Methods Mol Biol 132 365 386 1:CAS:528:DyaK1MXmslKqsbo%3D 10547847
38. MW Pfaffl 2001 A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 e45 10.1093/nar/29.9.e45 1:STN:280:DC%2BD38nis12jtw%3D%3D 11328886
39. DL Coutu JH Wu A Monette GE Rivard MD Blostein J Galipeau 2008 Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells J Biol Chem 283 17991 18001 10.1074/jbc.M708029200 1:CAS:528:DC%2BD1cXnsVCgt7g%3D 18450759
40. MJ Flick X Du DP Witte M Jirouskova DA Soloviev SJ Busuttil, et al. 2004 Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo J Clin Invest 113 1596 1606 1:CAS:528:DC%2BD2cXkvVOqtr0%3D 15173886 (Pubitemid 39071683)
41. WJ Hu JW Eaton TP Ugarova L Tang 2001 Molecular basis of biomaterial-mediated foreign body reactions Blood 98 1231 1238 10.1182/blood.V98.4.1231 1:CAS:528:DC%2BD3MXmtFeit78%3D 11493475
42. L Tang JW Eaton 1993 Fibrin(ogen) mediates acute inflammatory responses to biomaterials J Exp Med 178 2147 2156 10.1084/jem.178.6.2147 1:CAS:528:DyaK3sXmtlequ7s%3D 8245787 (Pubitemid 23344872)
43. C Rubel S Gomez GC Fernandez MA Isturiz J Caamano MS Palermo 2003 Fibrinogen-CD11b/CD18 interaction activates the NF-kappa B pathway and delays apoptosis in human neutrophils Eur J Immunol 33 1429 1438 10.1002/eji.200323512 1:CAS:528:DC%2BD3sXjvFyjsLo%3D 12731070 (Pubitemid 36609162)
44. RG Sitrin PM Pan S Srikanth RF Todd III 1998 Fibrinogen activates NF-kappa B transcription factors in mononuclear phagocytes J Immunol 161 1462 1470 1:CAS:528:DyaK1cXltVeitbY%3D 9686612 (Pubitemid 28380578)
45. RR Cobb JL Molony 1996 Interleukin-1beta expression is induced by adherence and is enhanced by Fc-receptor binding to immune complex in THP-1 cells FEBS Lett 394 241 246 10.1016/0014-5793(96)00960-X 1:CAS:528: DyaK28XmtV2isLw%3D 8830651 (Pubitemid 26341451)
46. H Nagao 1998 Fibrinogen affects blood and bone marrow cell functions on titanium in vitro Kokubyo Gakkai Zasshi 65 53 63 1:CAS:528:DyaK1cXit12htb0%3D 9584421
47. D Di Iorio T Traini M Degidi S Caputi J Neugebauer A Piattelli 2005 Quantitative evaluation of the fibrin clot extension on different implant surfaces: an in vitro study J Biomed Mater Res B Appl Biomater 74 636 642 15803487 (Pubitemid 40917735)
48. T Jarmar A Palmquist R Branemark L Hermansson H Engqvist P Thomsen 2008 Characterization of the surface properties of commercially available dental implants using scanning electron microscopy, focused ion beam, and high-resolution transmission electron microscopy Clin Implant Dent Relat Res 10 11 22 10.1111/j.1708-8208.2007.00056.x 18254738
49. BS Kang YT Sul SJ Oh HJ Lee T Albrektsson 2009 XPS, AES and SEM analysis of recent dental implants Acta Biomater 5 2222 2229 10.1016/j.actbio.2009.01.049 1:CAS:528:DC%2BD1MXosVagsro%3D 19261554
50. S Roessler R Zimmermann D Scharnweber C Werner H Worch 2002 Characterization of oxide layers on Ti6Al4V and titanium by streaming potential and streaming current measurements Colloids Surf B: Biointerfaces 26 387 395 10.1016/S0927-7765(02)00025-5 1:CAS:528:DC%2BD38XmtlGqsL8%3D (Pubitemid 34919413)
51. K Cai M Frant J Bossert G Hildebrand K Liefeith KD Jandt 2006 Surface functionalized titanium thin films: zeta-potential, protein adsorption and cell proliferation Colloids Surf B: Biointerfaces 50 1 8 10.1016/j.colsurfb.2006.03. 016 1:CAS:528:DC%2BD28XltlKjur8%3D (Pubitemid 44208834)
52. HM Kim T Himeno M Kawashita JH Lee T Kokubo T Nakamura 2003 Surface potential change in bioactive titanium metal during the process of apatite formation in simulated body fluid J Biomed Mater Res A 67 1305 1309 10.1002/jbm.a.20039 14624517 (Pubitemid 37522744)
53. DE MacDonald N Deo B Markovic M Stranick P Somasundaran 2002 Adsorption and dissolution behavior of human plasma fibronectin on thermally and chemically modified titanium dioxide particles Biomaterials 23 1269 1279 10.1016/S0142-9612(01)00317-9 1:CAS:528:DC%2BD3MXos1WqurY%3D 11791930 (Pubitemid 33109058)
54. IO Smith MJ Baumann LR McCabe 2004 Electrostatic interactions as a predictor for osteoblast attachment to biomaterials J Biomed Mater Res A 70 436 441 10.1002/jbm.a.30098 1:STN:280:DC%2BD2czovVCnsg%3D%3D 15293317
55. Cooper JJ, Hunt JA. The significance of zeta potential in osteogenesis. Society for Biomaterials Annual Meeting. Pennsylvania, USA; 2006.
56. B Nebe B Finke F Luthen C Bergemann K Schroder J Rychly, et al. 2007 Improved initial osteoblast functions on amino-functionalized titanium surfaces Biomol Eng 24 447 454 10.1016/j.bioeng.2007.07.004 1:CAS:528: DC%2BD2sXhtlGiu7%2FL 17825608 (Pubitemid 350123171)
57. Larsson C, Esposito M, Liao H, Thomsen P. Titanium-bone interface in vivo. In: Brunette DM, Tengvall P, Textor M, Thomsen P, editors. Titanium in medicine. New York: Springer; 2001. p. 587-648.
58. M Kalltorp S Oblogina S Jacobsson A Karlsson P Tengvall P Thomsen 1999 In vivo cell recruitment, cytokine release and chemiluminescence response at gold, and thiol functionalized surfaces Biomaterials 20 2123 2137 10.1016/S0142-9612(99)00115-5 1:CAS:528:DyaK1MXntFClsLo%3D 10555080 (Pubitemid 29488661)
59. E Jansson M Kalltorp P Thomsen P Tengvall 2002 Ex vivo PMA-induced respiratory burst and TNF-alpha secretion elicited from inflammatory cells on machined and porous blood plasma clot-coated titanium Biomaterials 23 2803 2815 10.1016/S0142-9612(02)00021-2 1:CAS:528:DC%2BD38XjsVSqtr0%3D 12059032 (Pubitemid 34465741)
60. F Suska M Esposito C Gretzer M Kalltorp P Tengvall P Thomsen 2003 IL-1alpha, IL-1beta and TNF-alpha secretion during in vivo/ex vivo cellular interactions with titanium and copper Biomaterials 24 461 468 10.1016/S0142-9612(02)00359-9 1:CAS:528:DC%2BD38XotlKgsbg%3D 12423601 (Pubitemid 35291199)
61. J Ma J Ge S Zhang A Sun J Shen L Chen, et al. 2005 Time course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarction Basic Res Cardiol 100 217 223 10.1007/s00395-005-0521-z 1:CAS:528:DC%2BD2MXkslKls7w%3D 15754085 (Pubitemid 41348812)
62. Z Cheng X Liu L Ou X Zhou Y Liu X Jia, et al. 2008 Mobilization of mesenchymal stem cells by granulocyte colony-stimulating factor in rats with acute myocardial infarction Cardiovasc Drugs Ther 22 363 371 10.1007/s10557-008-6110-2 1:CAS:528:DC%2BD1cXhtVOntr3N 18461431
63. Y Wang Y Deng GQ Zhou 2008 SDF-1alpha/CXCR4-mediated migration of systemically transplanted bone marrow stromal cells towards ischemic brain lesion in a rat model Brain Res 1195 104 112 10.1016/j.brainres.2007.11.068 1:CAS:528:DC%2BD1cXitVehur4%3D 18206136
64. S Otsuru K Tamai T Yamazaki H Yoshikawa Y Kaneda 2008 Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway Stem Cells 26 223 234 10.1634/stemcells.2007-0515 1:CAS:528:DC%2BD1cXhvVCktbo%3D 17932420
65. BR Son LA Marquez-Curtis M Kucia M Wysoczynski AR Turner J Ratajczak, et al. 2006 Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases Stem Cells 24 1254 1264 10.1634/stemcells.2005-0271 1:CAS:528:DC%2BD28XhtFGhu7fM 16410389 (Pubitemid 44464694)
66. RC Furze SM Rankin 2008 Neutrophil mobilization and clearance in the bone marrow Immunology 125 281 288 10.1111/j.1365-2567.2008.02950.x 1:CAS:528:DC%2BD1cXhtlOgtLvF 19128361
67. H Nagase M Miyamasu M Yamaguchi M Imanishi NH Tsuno K Matsushima, et al. 2002 Cytokine-mediated regulation of CXCR4 expression in human neutrophils J Leukoc Biol 71 711 717 1:CAS:528:DC%2BD38XivFGkt7g%3D 11927659
68. C Martin PC Burdon G Bridger JC Gutierrez-Ramos TJ Williams M Rankin 2003 Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence Immunity 19 583 593 10.1016/S1074-7613(03)00263-2 1:CAS:528:DC%2BD3sXosF2rsrc%3D 14563322 (Pubitemid 37311439)
69. BD Boyan Z Schwartz 2006 Response of musculoskeletal cells to biomaterials J Am Acad Orthop Surg 14 S157 S162 17003190
70. S Gronthos PJ Simmons SE Graves PG Robey 2001 Integrin-mediated interactions between human bone marrow stromal precursor cells and the extracellular matrix Bone 28 174 181 10.1016/S8756-3282(00)00424-5 1:CAS:528:DC%2BD3MXhtFehu7s%3D 11182375 (Pubitemid 32140973)
71. G Gronowicz MB McCarthy 1996 Response of human osteoblasts to implant materials: integrin-mediated adhesion J Orthop Res 14 878 887 10.1002/jor.1100140606 1:CAS:528:DyaK2sXntFaktg%3D%3D 8982129 (Pubitemid 27044455)
72. B Setzer M Bachle MC Metzger R Kohal 2009 J. The gene-expression and phenotypic response of hFOB 1.19 osteoblasts to surface-modified titanium and zirconia Biomaterials 30 979 990 10.1016/j.biomaterials.2008.10.054 1:CAS:528:DC%2BD1cXhsFCisrfP 19027946
73. T Ogawa I Nishimura 2003 Different bone integration profiles of turned and acid etched implants associated with modulated expression of extracellular matrix genes Int J Oral Maxillofac Implants 18 200 210 12705297 (Pubitemid 37162402)
74. S Ozawa T Ogawa K Iida C Sukotjo H Hasegawa RD Nishimura, et al. 2002 Ovariectomy hinders the early stage of bone-implant integration: histomorphometric, biomechanical, and molecular analyses Bone 30 137 143 10.1016/S8756-3282(01)00646-9 1:CAS:528:DC%2BD38XktFCjtw%3D%3D 11792576 (Pubitemid 34044311)
75. DE Hughes DM Salter S Dedhar R Simpson 1993 Integrin expression in human bone J Bone Miner Res 8 527 533 10.1002/jbmr.5650080503 1:CAS:528: DyaK2cXivFCkt7s%3D 8511980 (Pubitemid 23127912)