Janus: Prediction and ranking of mutations required for functional interconversion of enzymes

Journal of Molecular Biology

Volumn 425, Issue 8, 2013, Pages 1378-1389

  Addington, Trevor A ^a   Mertz, Robert W ^a   Siegel, Justin B ^a,b   Thompson, James M ^c   Fisher, Andrew J ^a   Filkov, Vladimir ^d   Fleischman, Nicholas M ^a   Suen, Alisa A ^a   Zhang, Chensong ^a   Toney, Michael D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d University of California   (United States)

Author keywords

bioinformatics; computational modeling; directed evolution; enzymology; protein engineering

Indexed keywords

ASPARTATE AMINOTRANSFERASE; TYROSINE AMINOTRANSFERASE;

ACCURACY; ARTICLE; BIOINFORMATICS; CATALYSIS; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; JANUS; MUTATION; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; WILD TYPE;

EID: 84875734662     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.01.034     Document Type: Article

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