Quantitative chimeric analysis of six specificity determinants that differentiate Escherichia coli aspartate from tyrosine aminotransferase

Protein Science

Volumn 11, Issue 12, 2002, Pages 2848-2859

  Shaffer, Wendy A ^a   Luong, Tinh N ^a   Rothman, Steven C ^a   Kirsch, Jack F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aminotransferase; Chimera; Context dependence; Protein genetic engineering; Pyridoxal phosphate; Substrate specificity

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BACTERIAL ENZYME; CHIMERIC PROTEIN; DIMER; IMINE; PYRIDOXAL 5 PHOSPHATE; TYROSINE AMINOTRANSFERASE; ASPARTIC ACID; HYBRID PROTEIN; PHENYLALANINE;

ARTICLE; CHEMICAL REACTION KINETICS; CHIMERA; ELECTRICITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE MUTATION; MOLECULAR STABILITY; PKA; PRIORITY JOURNAL; PROTEIN ENGINEERING; QUANTITATIVE ANALYSIS; SPECTROPHOTOMETRY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MUTATION; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

ASPARTATE AMINOTRANSFERASES; ASPARTIC ACID; ESCHERICHIA COLI; KINETICS; MOLECULAR STRUCTURE; MUTATION; PHENYLALANINE; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TYROSINE TRANSAMINASE;

EID: 0036892433     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0221902     Document Type: Article

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