Interference in DNA Replication Can Cause Mitotic Chromosomal Breakage Unassociated with Double-Strand Breaks

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Fujita, Mari ^a   Sasanuma, Hiroyuki ^a   Yamamoto, Kimiyo N ^a   Harada, Hiroshi ^a   Kurosawa, Aya ^b   Adachi, Noritaka ^b   Omura, Masato ^a   Hiraoka, Masahiro ^c   Takeda, Shunichi ^a   Hirota, Kouji ^a  

^a KYOTO UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APHIDICOLIN; ATR PROTEIN; CELL PROTEIN; DNA; DOUBLE STRANDED DNA; FLUOROURACIL; HYDROXYUREA; PROTEIN ATRIP; PROTEIN PIF1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL COUNT; CELL CYCLE; CELL LINE; CHICKEN; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; ENZYME ACTIVITY; GENETIC ANALYSIS; GENETIC REGULATION; HUMAN; HUMAN CELL; MITOSIS; MOLECULAR MECHANICS; NONHUMAN; SINGLE STRANDED DNA BREAK;

ANIMALS; ANTIGENS, NUCLEAR; APHIDICOLIN; APOPTOSIS; CELL LINE, TUMOR; CHICKENS; CHROMOSOME BREAKAGE; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA REPAIR; DNA REPAIR ENZYMES; DNA REPLICATION; DNA-BINDING PROTEINS; FLUOROURACIL; GENE KNOCKOUT TECHNIQUES; HUMANS; HYDROXYUREA; MITOSIS;

EID: 84875702315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060043     Document Type: Article

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