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Volumn 68, Issue 2, 2013, Pages 167-172

CTNNB1, AXIN1 and APC expression analysis of different medulloblastoma variants

Author keywords

catenin; Gene expression; Immunohistochemistry; Medulloblastoma; Wnt pathway

Indexed keywords

APC PROTEIN; AXIN; AXIN1 PROTEIN, HUMAN; BETA CATENIN; CTNNB1 PROTEIN, HUMAN;

EID: 84875652172     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.6061/clinics/2013(02)OA08     Document Type: Article
Times cited : (22)

References (49)
  • 1
    • 84973176275 scopus 로고    scopus 로고
    • In WHO classification of tumors of the central nervous system Eds DN Louis, H Ohgaki, OD Wiestler, WK Cavenee, IARC, France
    • Giangaspero F, Eberhart CG, Haapasala H, Pietsch T, Wiestler OD, Ellison DW. Medulloblastoma. In WHO classification of tumors of the central nervous system Eds DN Louis, H Ohgaki, OD Wiestler, WK Cavenee, IARC, France, 2007:132-40.
    • (2007) Medulloblastoma , pp. 132-140
    • Giangaspero, F.1    Eberhart, C.G.2    Haapasala, H.3    Pietsch, T.4    Wiestler, O.D.5    Ellison, D.W.6
  • 2
    • 0031846499 scopus 로고    scopus 로고
    • Prognostic factors in medulloblastoma
    • Giordana MT, Schiffer P, Schiffer D. Prognostic factors in medulloblastoma. Child9s Nerv Syst. 1998;14(6):256-62, http://dx.doi.org/10.1007/s003810050221.
    • (1998) Child9s Nerv Syst. , vol.14 , Issue.6 , pp. 256-262
    • Giordana, M.T.1    Schiffer, P.2    Schiffer, D.3
  • 3
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO Classification of tumors of the Central Nervous System
    • Louis ND, Ohgaki H, Wiestler DO, Cavenee KW, Burger CP, Jouvet A, et al. The 2007 WHO Classification of tumors of the Central Nervous System. Acta Neuropathol. 2007;114(2):97-109, http://dx.doi.org/10. 1007/s00401-007-0243-4.
    • (2007) Acta Neuropathol. , vol.114 , Issue.2 , pp. 97-109
    • Louis, N.D.1    Ohgaki, H.2    Wiestler, D.O.3    Cavenee, K.W.4    Burger, C.P.5    Jouvet, A.6
  • 4
    • 55749108014 scopus 로고    scopus 로고
    • Pathological and molecular heterogeneity of medulloblastoma
    • Gulino A, Arcella A, Giangaspero F. Pathological and molecular heterogeneity of medulloblastoma. Curr Opin Oncol. 2008;20(6):668-75, http://dx.doi.org/10.1097/CCO.0b013e32831369f4.
    • (2008) Curr Opin Oncol. , vol.20 , Issue.6 , pp. 668-675
    • Gulino, A.1    Arcella, A.2    Giangaspero, F.3
  • 5
    • 33646362581 scopus 로고    scopus 로고
    • Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations
    • Thompson MC, Fuller C, Hogg TL, Dalton J, Finkelstein D, Lau CC, et al. Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol. 2006;24(12):1924-31, http://dx. doi.org/10.1200/JCO.2005.04.4974.
    • (2006) J Clin Oncol. , vol.24 , Issue.12 , pp. 1924-1931
    • Thompson, M.C.1    Fuller, C.2    Hogg, T.L.3    Dalton, J.4    Finkelstein, D.5    Lau, C.C.6
  • 6
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • pone.0003088
    • Kool M, Koster J, Bunt J, Hasselt NE, Lakeman A, van Sluis P, et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One. 2008;3(8):e3088, http://dx.doi.org/10.1371/journal. pone.0003088.
    • (2008) PLoS One. , vol.3 , Issue.8
    • Kool, M.1    Koster, J.2    Bunt, J.3    Hasselt, N.E.4    Lakeman, A.5    van Sluis, P.6
  • 8
    • 79954991010 scopus 로고    scopus 로고
    • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
    • Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, et al. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol. 2011;29(11):1424-30, http://dx.doi.org/10.1200/JCO.2010.28.5148.
    • (2011) J Clin Oncol. , vol.29 , Issue.11 , pp. 1424-1430
    • Cho, Y.J.1    Tsherniak, A.2    Tamayo, P.3    Santagata, S.4    Ligon, A.5    Greulich, H.6
  • 9
    • 84863393028 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
    • Kool M, Korshunov A, Remke M, Jones DT, Schlanstein M, Northcott PA, et al. Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol. 2012;123(4):473-84, http://dx.doi.org/10.1007/s00401-012-0958-8.
    • (2012) Acta Neuropathol. , vol.123 , Issue.4 , pp. 473-484
    • Kool, M.1    Korshunov, A.2    Remke, M.3    Jones, D.T.4    Schlanstein, M.5    Northcott, P.A.6
  • 11
    • 33751234205 scopus 로고    scopus 로고
    • Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
    • Clifford SC, Lusher ME, Lindsey JC, Langdon JA, Gilbertson RJ, Straughton D, et al. Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle. 2006;5(22):2666-70, http://dx.doi.org/10.4161/cc.5.22.3446.
    • (2006) Cell Cycle. , vol.5 , Issue.22 , pp. 2666-2670
    • Clifford, S.C.1    Lusher, M.E.2    Lindsey, J.C.3    Langdon, J.A.4    Gilbertson, R.J.5    Straughton, D.6
  • 12
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodar, A & Nusse, R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev Biol. 1998;14:59-88, http://dx.doi.org/10.1146/annurev.cellbio.14.1.59.
    • (1998) Annu. Rev. Cell Dev Biol. , vol.14 , pp. 59-88
    • Wodar, A.1    Nusse, R.2
  • 13
    • 0038636318 scopus 로고    scopus 로고
    • Tumor formation by genetic mutations in the components of the Wnt signaling pathway
    • Kikuchi A. Tumor formation by genetic mutations in the components of the Wnt signaling pathway. Cancer Sci. 2003;94(3):225-9, http://dx.doi. org/10.1111/j.1349-7006.2003.tb01424.x.
    • (2003) Cancer Sci. , vol.94 , Issue.3 , pp. 225-229
    • Kikuchi, A.1
  • 14
    • 0033486152 scopus 로고    scopus 로고
    • Beta-catenin signaling and cancer
    • CO;2-P
    • Morin PJ. Beta-catenin signaling and cancer. Bioessays. 1999;21(12):1021-30, http://dx.doi.org/10.1002/(SICI)1521-1878(199912)22:1,1021::AIDBIES6.3.0. CO;2-P.
    • (1999) Bioessays. , vol.21 , Issue.12 , pp. 1021-1030
    • Morin, P.J.1
  • 15
    • 0035395236 scopus 로고    scopus 로고
    • Beta-catenin mutation and over expression in hepatocellular carcinoma
    • Wong CM, Fan ST, Ng IO. Beta-catenin mutation and over expression in hepatocellular carcinoma. Cancer. 2001;92(1):136-45, http://dx.doi.org/10.1002/1097-0142(20010701)92:1,136::AID-CNCR1301.3.0.CO;2-R.
    • (2001) Cancer. , vol.92 , Issue.1 , pp. 136-145
    • Wong, C.M.1    Fan, S.T.2    Ng, I.O.3
  • 16
    • 0037367866 scopus 로고    scopus 로고
    • Wnt signaling in hepatocellular carcinoma: Analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes
    • Cui J, Zhou X, Liu Y, Tang Z, Romeih M. Wnt signaling in hepatocellular carcinoma: analysis of mutation and expression of beta-catenin, T-cell factor-4 and glycogen synthase kinase 3-beta genes. J Gastroenterol Hepatol. 2003;18(3):280-7, http://dx.doi.org/10.1046/j.1440-1746.2003. 02973.x.
    • (2003) J Gastroenterol Hepatol. , vol.18 , Issue.3 , pp. 280-287
    • Cui, J.1    Zhou, X.2    Liu, Y.3    Tang, Z.4    Romeih, M.5
  • 17
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275(5307):1787-90, http://dx.doi.org/10.1126/science.275.5307.1787.
    • (1997) Science. , vol.275 , Issue.5307 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3    Barker, N.4    Clevers, H.5    Vogelstein, B.6
  • 18
    • 0030944065 scopus 로고    scopus 로고
    • Beta-catenin as oncogene: The smoking gun
    • Peifer M. Beta-catenin as oncogene: the smoking gun. Science. 1997;275(5307):1752-3, http://dx.doi.org/10.1126/science.275.5307.1752.
    • (1997) Science. , vol.275 , Issue.5307 , pp. 1752-1753
    • Peifer, M.1
  • 19
    • 0033788835 scopus 로고    scopus 로고
    • Plakoglobin and b-catenin: Protein interactions, regulation and biological roles
    • Zhurinsky J, Sctutman M, Bem-Ze'ev A. Plakoglobin and b-catenin: protein interactions, regulation and biological roles. J Cell Sci. 2000;113 (Pt 18):3127-39.
    • (2000) J Cell Sci. , vol.113 , Issue.PART 18 , pp. 3127-3139
    • Zhurinsky, J.1    Sctutman, M.2    Bem-Ze'ev, A.3
  • 20
    • 0035252879 scopus 로고    scopus 로고
    • The LDL receptor gene family: Signalling functions during development
    • Howell BW, Hertz J. The LDL receptor gene family: signalling functions during development. Curr Opin Neurobiol. 2001;11(1):74-81, http://dx. doi.org/10.1016/S0959-4388(00)00176-8.
    • (2001) Curr Opin Neurobiol. , vol.11 , Issue.1 , pp. 74-81
    • Howell, B.W.1    Hertz, J.2
  • 21
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polaskis P. Wnt signaling and cancer. Genes Dev. 2007;14:1837-51.
    • (2007) Genes Dev. , vol.14 , pp. 1837-1851
    • Polaskis, P.1
  • 22
    • 0002942476 scopus 로고
    • Antigen unmasking in formalin-fixed routinely processed paraffin wasembedded section by pressure cooking: A comparison with microwave oven heating and traditional methods
    • Miller K, Auld J, Jessup E, Rhodes A, Ashton-Key M. Antigen unmasking in formalin-fixed routinely processed paraffin wasembedded section by pressure cooking: A comparison with microwave oven heating and traditional methods. Advances Anat Pathol. 1995;2:60-4, http://dx.doi.org/10.1097/00125480-199501000-00044.
    • (1995) Advances Anat Pathol. , vol.2 , pp. 60-64
    • Miller, K.1    Auld, J.2    Jessup, E.3    Rhodes, A.4    Ashton-Key, M.5
  • 23
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabed antibody (PAP) procedure
    • Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabed antibody (PAP) procedure. J Histochem Cytochem. 1981;29(4):577-80, http://dx.doi.org/10.1177/29.4.6166661.
    • (1981) J Histochem Cytochem. , vol.29 , Issue.4 , pp. 577-580
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) Method. Methods. 2001;25(4):402-8, http://dx.doi.org/10.1006/meth.2001.1262.
    • (2001) Methods. , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0034033921 scopus 로고    scopus 로고
    • Nuclear localization and mutation of beta-catenin in medulloblastomas
    • Eberhart CG, Tihan T, Burger PC. Nuclear localization and mutation of beta-catenin in medulloblastomas. J Neuropathol Exp Neurol. 2000;59(4):333-37.
    • (2000) J Neuropathol Exp Neurol. , vol.59 , Issue.4 , pp. 333-337
    • Eberhart, C.G.1    Tihan, T.2    Burger, P.C.3
  • 26
    • 11844301282 scopus 로고    scopus 로고
    • Medulloblastoma: Developmental mechanisms out of control
    • Marino S. Medulloblastoma: developmental mechanisms out of control. Trends Mol Med. 2005;11(1):17-22, http://dx.doi.org/10.1016/j.molmed. 2004.11.008.
    • (2005) Trends Mol Med. , vol.11 , Issue.1 , pp. 17-22
    • Marino, S.1
  • 27
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signaling in stem cells and cancer
    • Reya T, Clevers H. Wnt signaling in stem cells and cancer. Nature 2005; 434:843-50, http://dx.doi.org/10.1038/nature03319.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 28
    • 33745389589 scopus 로고    scopus 로고
    • Medulloblastoma: Histopathologic and molecular markers of anaplasia and biologic behavior
    • Min HS, Lee YJ, Park K, Cho BK, Park SH. Medulloblastoma: histopathologic and molecular markers of anaplasia and biologic behavior. Acta Neuropathol. 2006;112(1):13-20, http://dx.doi.org/10. 1007/s00401-006-0073-9.
    • (2006) Acta Neuropathol. , vol.112 , Issue.1 , pp. 13-20
    • Min, H.S.1    Lee, Y.J.2    Park, K.3    Cho, B.K.4    Park, S.H.5
  • 30
    • 32944461274 scopus 로고    scopus 로고
    • B-catenin status predicts a favorable outcome in childhood medulloblastoma: The United Kingdom Children's Cancer study group brain tumour Committee
    • Ellison DW, Onilude OE, Lindsey JC, Lusher ME, Weston CL, Taylor RE, et al. b-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer study group brain tumour Committee. J Clin Oncol. 2005;23(31):7951-7, http://dx.doi. org/10.1200/JCO.2005.01.5479.
    • (2005) J Clin Oncol. , vol.23 , Issue.31 , pp. 7951-7957
    • Ellison, D.W.1    Onilude, O.E.2    Lindsey, J.C.3    Lusher, M.E.4    Weston, C.L.5    Taylor, R.E.6
  • 31
    • 79954992066 scopus 로고    scopus 로고
    • Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables
    • Ellison DW, Kocak M, Dalton J, Megahed H, Lusher ME, Ryan SL, et al. Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clinic Oncol. 2011;29(11):1400-7, http://dx.doi.org/10.1200/JCO.2010. 30.2810.
    • (2011) J Clinic Oncol. , vol.29 , Issue.11 , pp. 1400-1407
    • Ellison, D.W.1    Kocak, M.2    Dalton, J.3    Megahed, H.4    Lusher, M.E.5    Ryan, S.L.6
  • 32
    • 0037151060 scopus 로고    scopus 로고
    • ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas
    • Schroeder JA, Adriance MC, McConnell EJ, Thompson MC, Pockaj B, Gendler SJ. ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas. J Biol Chem. 2002;277(25):22692-8, http://dx.doi.org/10.1074/jbc.M201975200.
    • (2002) J Biol Chem. , vol.277 , Issue.25 , pp. 22692-22698
    • Schroeder, J.A.1    Adriance, M.C.2    McConnell, E.J.3    Thompson, M.C.4    Pockaj, B.5    Gendler, S.J.6
  • 33
    • 0035955642 scopus 로고    scopus 로고
    • Suppressor of fused negatively regulates beta-catenin signaling
    • Meng X, Poon R, Zhang X, Cheah A, Ding Q, Hui CC, Alman B. Suppressor of fused negatively regulates beta-catenin signaling. J Biol Chem. 2001;276(43):40113-9, http://dx.doi.org/10.1074/jbc.M105317200.
    • (2001) J Biol Chem. , vol.276 , Issue.43 , pp. 40113-40119
    • Meng, X.1    Poon, R.2    Zhang, X.3    Cheah, A.4    Ding, Q.5    Hui, C.C.6    Alman, B.7
  • 34
    • 0033392501 scopus 로고    scopus 로고
    • The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin
    • Taya S, Yamamoto T, Kanai-Azuma M, Wood SA, Kaibuchi K. The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin. Genes Cells. 1999;4(12):757-67, http://dx.doi.org/10.1046/j.1365-2443. 1999.00297.x.
    • (1999) Genes Cells. , vol.4 , Issue.12 , pp. 757-767
    • Taya, S.1    Yamamoto, T.2    Kanai-Azuma, M.3    Wood, S.A.4    Kaibuchi, K.5
  • 35
    • 0035200844 scopus 로고    scopus 로고
    • FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development
    • Pantaleon M, Kanai-Azuma M, Mattick JS, Kaibuchi K, Kaye PL, Wood SA. FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mech Dev. 2001;109(2):151-60, http://dx. doi.org/10.1016/S0925-4773(01)00551-2.
    • (2001) Mech Dev. , vol.109 , Issue.2 , pp. 151-160
    • Pantaleon, M.1    Kanai-Azuma, M.2    Mattick, J.S.3    Kaibuchi, K.4    Kaye, P.L.5    Wood, S.A.6
  • 36
    • 1542297761 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of axin regulates subcellular localization of beta-catenin
    • Cong F, Varmus H. Nuclear-cytoplasmic shuttling of axin regulates subcellular localization of beta-catenin. Proc Natl Acad Sci USA. 2004;101(9):2882-7, http://dx.doi.org/10.1073/pnas.0307344101.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , Issue.9 , pp. 2882-2887
    • Cong, F.1    Varmus, H.2
  • 37
    • 0034282097 scopus 로고    scopus 로고
    • Nuclear-cytoplasmic shuttling of APC regulates betacatenin subcellular localization and turnover
    • Henderson BR. Nuclear-cytoplasmic shuttling of APC regulates betacatenin subcellular localization and turnover. Nat Cell Biol. 2000;2(9):653-60, http://dx.doi.org/10.1038/35023605.
    • (2000) Nat Cell Biol. , vol.2 , Issue.9 , pp. 653-660
    • Henderson, B.R.1
  • 38
    • 28544448610 scopus 로고    scopus 로고
    • Muc1 oncoprotein blocks glycogen synthase kinase 3b-mediated phosphorylation and degradation of b-catenin
    • Huang L, Chen D, Liu D, Yin L, Kharbanda S, Kufe D. Muc1 oncoprotein blocks glycogen synthase kinase 3b-mediated phosphorylation and degradation of b-catenin. Cancer Res. 2005;65(22):10413-22, http://dx. doi.org/10.1158/0008-5472.CAN-05-2474.
    • (2005) Cancer Res. , vol.65 , Issue.22 , pp. 10413-10422
    • Huang, L.1    Chen, D.2    Liu, D.3    Yin, L.4    Kharbanda, S.5    Kufe, D.6
  • 39
    • 64949083548 scopus 로고    scopus 로고
    • An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET)
    • bjc.6604979
    • Rogers HA, Miller S, Lowe J, Brundler MA, Coyle B, Grundy RG. An investigation of WNT pathway activation and association with survival in central nervous system primitive neuroectodermal tumours (CNS PNET). Br J Cancer. 2009;100(8):1292-302, http://dx.doi.org/10.1038/sj. bjc.6604979.
    • (2009) Br J Cancer. , vol.100 , Issue.8 , pp. 1292-1302
    • Rogers, H.A.1    Miller, S.2    Lowe, J.3    Brundler, M.A.4    Coyle, B.5    Grundy, R.G.6
  • 40
    • 79959803041 scopus 로고    scopus 로고
    • Expression of Gli1 and PARP1 in medulloblastoma: An immunohistochemical study of 65 cases
    • Pizem J, Popovic M, Cö r A. Expression of Gli1 and PARP1 in medulloblastoma: an immunohistochemical study of 65 cases. J Neurooncol. 2010;103(3):459-67.
    • (2010) J Neurooncol. , vol.103 , Issue.3 , pp. 459-467
    • Pizem, J.1    Popovic, M.2    Cör, A.3
  • 41
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, et al. The genetic landscape of the childhood cancer medulloblastoma. Science. 2011;331(6016):435-9, http://dx.doi.org/10.1126/science.1198056.
    • (2011) Science. , vol.331 , Issue.6016 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3    Jones, S.4    Leary, R.J.5    Lin, J.C.6
  • 42
    • 0034739023 scopus 로고    scopus 로고
    • The APC tumour suppressor has a nuclear export function
    • Rosin-Arbesfeld R, Townsley F, Bienz M. The APC tumour suppressor has a nuclear export function. Nature. 2000;406(6799):1009-12.
    • (2000) Nature , vol.406 , Issue.6799 , pp. 1009-1012
    • Rosin-Arbesfeld, R.1    Townsley, F.2    Bienz, M.3
  • 43
    • 0032946753 scopus 로고    scopus 로고
    • Expansion of CNS precursor pools: A new role for Sonic Hedgehog
    • Wechsler-Reya RJ, Scott MP. Expansion of CNS precursor pools: a new role for Sonic Hedgehog. Neuron. 1999;22(1):2-3.
    • (1999) Neuron. , vol.22 , Issue.1 , pp. 2-3
    • Wechsler-Reya, R.J.1    Scott, M.P.2
  • 45
    • 0037473082 scopus 로고    scopus 로고
    • AXIN1 mutations but not deletions in cerebellar medulloblastomas
    • Baeza N, Masuoka J, Kleihues P, Ohgaki H. AXIN1 mutations but not deletions in cerebellar medulloblastomas. Oncogene. 2003;22(4):632-6, http://dx.doi.org/10.1038/sj.onc.1206156.
    • (2003) Oncogene. , vol.22 , Issue.4 , pp. 632-636
    • Baeza, N.1    Masuoka, J.2    Kleihues, P.3    Ohgaki, H.4
  • 46
    • 34147124194 scopus 로고    scopus 로고
    • Intracellular distribution of beta-catenin in human medulloblastoma cell lines with different degree of neuronal differentiation
    • Salaroli R, Russo A, Ceccarelli C, Mina GD, Arcella A, Martinelli GN, et al. Intracellular distribution of beta-catenin in human medulloblastoma cell lines with different degree of neuronal differentiation. Ultrastruct Pathol. 2007;31(1):33-44, http://dx.doi.org/10.1080/01913120 601169501.
    • (2007) Ultrastruct Pathol. , vol.31 , Issue.1 , pp. 33-44
    • Salaroli, R.1    Russo, A.2    Ceccarelli, C.3    Mina, G.D.4    Arcella, A.5    Martinelli, G.N.6
  • 47
    • 77952671657 scopus 로고    scopus 로고
    • The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma
    • Kongkham PN, Northcott PA, Croul SE, Smith CA, Taylor MD, Rutka JT. The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma. Oncogene. 2010;29 (20):3017-24, http://dx.doi.org/10.1038/onc.2010.32.
    • (2010) Oncogene. , vol.29 , Issue.20 , pp. 3017-3024
    • Kongkham, P.N.1    Northcott, P.A.2    Croul, S.E.3    Smith, C.A.4    Taylor, M.D.5    Rutka, J.T.6
  • 48
    • 42549096546 scopus 로고    scopus 로고
    • Beyond Wnt inhibition: New functions of secreted Frizzled-related proteins in development and disease
    • Bovolenta P, Esteve P, Ruiz JM, Cisneros E, Lopez-Rios J. Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J Cell Sci. 2008;121(Pt 6):737-46, http://dx. doi.org/10.1242/jcs.026096.
    • (2008) J Cell Sci. , vol.121 , Issue.PART 6 , pp. 737-746
    • Bovolenta, P.1    Esteve, P.2    Ruiz, J.M.3    Cisneros, E.4    Lopez-Rios, J.5
  • 49
    • 65849356587 scopus 로고    scopus 로고
    • Beta-catenin status in paediatric medulloblastomas: Correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical Characteristics
    • Fattet S, Haberler C, Legoix P, Varlet P, Lellouch-Tubiana A, Lair S, Manie E, et al. Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical Characteristics. J Pathol. 2009;218(1):86-94, http://dx.doi.org/10.1002/path.2514.
    • (2009) J Pathol. , vol.218 , Issue.1 , pp. 86-94
    • Fattet, S.1    Haberler, C.2    Legoix, P.3    Varlet, P.4    Lellouch-Tubiana, A.5    Lair, S.6    Manie, E.7


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