Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Hussain, Azhar R ^a   Uddin, Shahab ^a   Ahmed, Maqbool ^a   Al Dayel, Fouad ^a   Bavi, Prashant P ^a   Al Kuraya, Khawla S ^a,b  

^a KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^b ALFAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR 5; I KAPPA B ALPHA; REACTIVE OXYGEN METABOLITE; THYMOQUINONE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADULT; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; BLACK CUMIN; CANCER PROGNOSIS; CANCER SURVIVAL; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CELL VIABILITY; COHORT ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LARGE CELL LYMPHOMA; LYMPHOMA CELL; MAJOR CLINICAL STUDY; MALE; PREDICTION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; TISSUE MICROARRAY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOQUINONES; CELL LINE, TUMOR; COHORT STUDIES; FEMALE; HUMANS; I-KAPPA B PROTEINS; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED; NIGELLA SATIVA; PHOSPHORYLATION; PROGNOSIS; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; UP-REGULATION;

NIGELLA SATIVA;

EID: 84875548465     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060540     Document Type: Article

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