-
1
-
-
67650506105
-
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
-
Tang Y., Wu X., Lei W., Pang L., Wan C., Shi Z., Zhao L., Nagy T.R., Peng X., Hu J., Feng X., Van Hul W., Wan M., Cao X. TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med. 2009, 15:757-765.
-
(2009)
Nat Med.
, vol.15
, pp. 757-765
-
-
Tang, Y.1
Wu, X.2
Lei, W.3
Pang, L.4
Wan, C.5
Shi, Z.6
Zhao, L.7
Nagy, T.R.8
Peng, X.9
Hu, J.10
Feng, X.11
Van Hul, W.12
Wan, M.13
Cao, X.14
-
2
-
-
0029980518
-
Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis
-
Sankar S., Mahooti-Brooks N., Bensen L., McCarthy T.L., Centrella M., Madri J.A. Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis. J. Clin. Invest. 1996, 97:1436-1446.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1436-1446
-
-
Sankar, S.1
Mahooti-Brooks, N.2
Bensen, L.3
McCarthy, T.L.4
Centrella, M.5
Madri, J.A.6
-
3
-
-
0033083517
-
Regulation by transforming growth factor-beta 1 of G1 cyclin-dependent kinases in human retinal epithelial cells
-
Pillaire M.J., Casagrande F., Malecaze F., Manenti S., Darbon J.M. Regulation by transforming growth factor-beta 1 of G1 cyclin-dependent kinases in human retinal epithelial cells. Exp. Eye Res. 1999, 68:193-199.
-
(1999)
Exp. Eye Res.
, vol.68
, pp. 193-199
-
-
Pillaire, M.J.1
Casagrande, F.2
Malecaze, F.3
Manenti, S.4
Darbon, J.M.5
-
4
-
-
0031438047
-
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
-
Heldin C.H., Miyazono K., ten Dijke P. TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 1997, 390:465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
ten Dijke, P.3
-
5
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R., Zhang Y.E. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003, 425:577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
6
-
-
77957783901
-
TGF-beta signaling in head and neck squamous cell carcinoma
-
White R.A., Malkoski S.P., Wang X.J. TGF-beta signaling in head and neck squamous cell carcinoma. Oncogene 2010, 29:5437-5446.
-
(2010)
Oncogene
, vol.29
, pp. 5437-5446
-
-
White, R.A.1
Malkoski, S.P.2
Wang, X.J.3
-
7
-
-
82355190200
-
TGF-beta signalling in colon carcinogenesis
-
Lampropoulos P., Zizi-Sermpetzoglou A., Rizos S., Kostakis A., Nikiteas N., Papavassiliou A.G. TGF-beta signalling in colon carcinogenesis. Cancer Lett. 2012, 314:1-7.
-
(2012)
Cancer Lett.
, vol.314
, pp. 1-7
-
-
Lampropoulos, P.1
Zizi-Sermpetzoglou, A.2
Rizos, S.3
Kostakis, A.4
Nikiteas, N.5
Papavassiliou, A.G.6
-
8
-
-
0032909086
-
Genetic events and the role of TGF beta in epithelial tumour progression
-
Akhurst R.J., Balmain A. Genetic events and the role of TGF beta in epithelial tumour progression. J. Pathol. 1999, 187:82-90.
-
(1999)
J. Pathol.
, vol.187
, pp. 82-90
-
-
Akhurst, R.J.1
Balmain, A.2
-
9
-
-
0030818246
-
Kips off to Myc: implications for TGF beta signaling
-
Alexandrow M.G., Moses H.L. Kips off to Myc: implications for TGF beta signaling. J. Cell Biochem. 1997, 66:427-432.
-
(1997)
J. Cell Biochem.
, vol.66
, pp. 427-432
-
-
Alexandrow, M.G.1
Moses, H.L.2
-
10
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
11
-
-
0029806099
-
Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines
-
Hsing A.Y., Kadomatsu K., Bonham M.J., Danielpour D. Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines. Cancer Res. 1996, 56:5146-5149.
-
(1996)
Cancer Res.
, vol.56
, pp. 5146-5149
-
-
Hsing, A.Y.1
Kadomatsu, K.2
Bonham, M.J.3
Danielpour, D.4
-
12
-
-
0031964370
-
Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model
-
Ashley D.M., Kong F.M., Bigner D.D., Hale L.P. Endogenous expression of transforming growth factor beta1 inhibits growth and tumorigenicity and enhances Fas-mediated apoptosis in a murine high-grade glioma model. Cancer Res. 1998, 58:302-309.
-
(1998)
Cancer Res.
, vol.58
, pp. 302-309
-
-
Ashley, D.M.1
Kong, F.M.2
Bigner, D.D.3
Hale, L.P.4
-
13
-
-
0033802727
-
Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex
-
Freathy C., Brown D.G., Roberts R.A., Cain K. Transforming growth factor-beta(1) induces apoptosis in rat FaO hepatoma cells via cytochrome c release and oligomerization of Apaf-1 to form a approximately 700-kd apoptosome caspase-processing complex. Hepatology 2000, 32:750-760.
-
(2000)
Hepatology
, vol.32
, pp. 750-760
-
-
Freathy, C.1
Brown, D.G.2
Roberts, R.A.3
Cain, K.4
-
14
-
-
0036136943
-
Mechanisms of TGF-beta-mediated apoptosis
-
Schuster N., Krieglstein K. Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res. 2002, 307:1-14.
-
(2002)
Cell Tissue Res.
, vol.307
, pp. 1-14
-
-
Schuster, N.1
Krieglstein, K.2
-
15
-
-
35448997708
-
Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1
-
Ehata S., Hanyu A., Hayashi M., Aburatani H., Kato Y., Fujime M., Saitoh M., Miyazawa K., Imamura T., Miyazono K. Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1. Cancer Res. 2007, 67:9694-9703.
-
(2007)
Cancer Res.
, vol.67
, pp. 9694-9703
-
-
Ehata, S.1
Hanyu, A.2
Hayashi, M.3
Aburatani, H.4
Kato, Y.5
Fujime, M.6
Saitoh, M.7
Miyazawa, K.8
Imamura, T.9
Miyazono, K.10
-
16
-
-
34248185926
-
Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression
-
Biswas S., Guix M., Rinehart C., Dugger T.C., Chytil A., Moses H.L., Freeman M.L., Arteaga C.L. Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. J. Clin. Invest. 2007, 117:1305-1313.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1305-1313
-
-
Biswas, S.1
Guix, M.2
Rinehart, C.3
Dugger, T.C.4
Chytil, A.5
Moses, H.L.6
Freeman, M.L.7
Arteaga, C.L.8
-
17
-
-
0030770411
-
Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation
-
Ehrhart E.J., Segarini P., Tsang M.L., Carroll A.G., Barcellos-Hoff M.H. Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation. Faseb J. 1997, 11:991-1002.
-
(1997)
Faseb J.
, vol.11
, pp. 991-1002
-
-
Ehrhart, E.J.1
Segarini, P.2
Tsang, M.L.3
Carroll, A.G.4
Barcellos-Hoff, M.H.5
-
18
-
-
33845358508
-
Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species
-
Jobling M.F., Mott J.D., Finnegan M.T., Jurukovski V., Erickson A.C., Walian P.J., Taylor S.E., Ledbetter S., Lawrence C.M., Rifkin D.B., Barcellos-Hoff M.H. Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species. Radiat. Res. 2006, 166:839-848.
-
(2006)
Radiat. Res.
, vol.166
, pp. 839-848
-
-
Jobling, M.F.1
Mott, J.D.2
Finnegan, M.T.3
Jurukovski, V.4
Erickson, A.C.5
Walian, P.J.6
Taylor, S.E.7
Ledbetter, S.8
Lawrence, C.M.9
Rifkin, D.B.10
Barcellos-Hoff, M.H.11
-
19
-
-
0033597206
-
A pivotal role for the transmembrane domain in transforming growth factor-beta receptor activation
-
Zhu H.J., Sizeland A.M. A pivotal role for the transmembrane domain in transforming growth factor-beta receptor activation. J. Biol. Chem. 1999, 274:11773-11781.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11773-11781
-
-
Zhu, H.J.1
Sizeland, A.M.2
-
20
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling
-
Souchelnytskyi S., Tamaki K., Engstrom U., Wernstedt C., ten Dijke P., Heldin C.H. Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling. J. Biol. Chem. 1997, 272:28107-28115.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engstrom, U.3
Wernstedt, C.4
ten Dijke, P.5
Heldin, C.H.6
-
21
-
-
0032479464
-
A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals
-
Goto D., Yagi K., Inoue H., Iwamoto I., Kawabata M., Miyazono K., Kato M. A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals. FEBS Lett. 1998, 430:201-204.
-
(1998)
FEBS Lett.
, vol.430
, pp. 201-204
-
-
Goto, D.1
Yagi, K.2
Inoue, H.3
Iwamoto, I.4
Kawabata, M.5
Miyazono, K.6
Kato, M.7
-
22
-
-
0030613249
-
TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
-
Abdollah S., Macias-Silva M., Tsukazaki T., Hayashi H., Attisano L., Wrana J.L. TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. J. Biol. Chem. 1997, 272:27678-27685.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27678-27685
-
-
Abdollah, S.1
Macias-Silva, M.2
Tsukazaki, T.3
Hayashi, H.4
Attisano, L.5
Wrana, J.L.6
-
23
-
-
42049107059
-
TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury
-
Buckley S., Shi W., Barsky L., Warburton D. TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury. Am. J. Physiol. Lung Cell Mol. Physiol. 2008, 294:L739-748.
-
(2008)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.294
-
-
Buckley, S.1
Shi, W.2
Barsky, L.3
Warburton, D.4
-
24
-
-
0036779327
-
Growth arrest in G1 protects against oxygen-induced DNA damage and cell death
-
Rancourt R.C., Hayes D.D., Chess P.R., Keng P.C., O'Reilly M.A. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. J. Cell Physiol. 2002, 193:26-36.
-
(2002)
J. Cell Physiol.
, vol.193
, pp. 26-36
-
-
Rancourt, R.C.1
Hayes, D.D.2
Chess, P.R.3
Keng, P.C.4
O'Reilly, M.A.5
-
25
-
-
3042713048
-
Transforming growth factor-beta is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33
-
Kim A.H., Lebman D.A., Dietz C.M., Snyder S.R., Eley K.W., Chung T.D. Transforming growth factor-beta is an endogenous radioresistance factor in the esophageal adenocarcinoma cell line OE-33. Int. J. Oncol. 2003, 23:1593-1599.
-
(2003)
Int. J. Oncol.
, vol.23
, pp. 1593-1599
-
-
Kim, A.H.1
Lebman, D.A.2
Dietz, C.M.3
Snyder, S.R.4
Eley, K.W.5
Chung, T.D.6
-
26
-
-
80455144497
-
TGF-beta1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo
-
Bouquet F., Pal A., Pilones K.A., Demaria S., Hann B., Akhurst R.J., Babb J.S., Lonning S.M., DeWyngaert J.K., Formenti S.C., Barcellos-Hoff M.H. TGF-beta1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo. Clin. Cancer Res. 2011, 17:6754-6765.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 6754-6765
-
-
Bouquet, F.1
Pal, A.2
Pilones, K.A.3
Demaria, S.4
Hann, B.5
Akhurst, R.J.6
Babb, J.S.7
Lonning, S.M.8
DeWyngaert, J.K.9
Formenti, S.C.10
Barcellos-Hoff, M.H.11
-
27
-
-
0037108674
-
Transforming growth factor-beta1 mediates cellular response to DNA damage in situ
-
Ewan K.B., Henshall-Powell R.L., Ravani S.A., Pajares M.J., Arteaga C., Warters R., Akhurst R.J., Barcellos-Hoff M.H. Transforming growth factor-beta1 mediates cellular response to DNA damage in situ. Cancer Res. 2002, 62:5627-5631.
-
(2002)
Cancer Res.
, vol.62
, pp. 5627-5631
-
-
Ewan, K.B.1
Henshall-Powell, R.L.2
Ravani, S.A.3
Pajares, M.J.4
Arteaga, C.5
Warters, R.6
Akhurst, R.J.7
Barcellos-Hoff, M.H.8
-
28
-
-
33845303212
-
Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress
-
Kirshner J., Jobling M.F., Pajares M.J., Ravani S.A., Glick A.B., Lavin M.J., Koslov S., Shiloh Y., Barcellos-Hoff M.H. Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress. Cancer Res. 2006, 66:10861-10869.
-
(2006)
Cancer Res.
, vol.66
, pp. 10861-10869
-
-
Kirshner, J.1
Jobling, M.F.2
Pajares, M.J.3
Ravani, S.A.4
Glick, A.B.5
Lavin, M.J.6
Koslov, S.7
Shiloh, Y.8
Barcellos-Hoff, M.H.9
-
29
-
-
13744253871
-
Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-beta1 depends on the enhanced TGF-beta signaling and requires the decreased phosphorylation of PKB/Akt
-
Ju E.M., Choi K.C., Hong S.H., Lee C.H., Kim B.C., Kim S.J., Kim I.H., Park S.H. Apoptosis of mink lung epithelial cells by co-treatment of low-dose staurosporine and transforming growth factor-beta1 depends on the enhanced TGF-beta signaling and requires the decreased phosphorylation of PKB/Akt. Biochem. Biophys. Res. Commun. 2005, 328:1170-1181.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.328
, pp. 1170-1181
-
-
Ju, E.M.1
Choi, K.C.2
Hong, S.H.3
Lee, C.H.4
Kim, B.C.5
Kim, S.J.6
Kim, I.H.7
Park, S.H.8
-
30
-
-
0038407335
-
Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells
-
Gong J., Ammanamanchi S., Ko T.C., Brattain M.G. Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells. Cancer Res. 2003, 63:3340-3346.
-
(2003)
Cancer Res.
, vol.63
, pp. 3340-3346
-
-
Gong, J.1
Ammanamanchi, S.2
Ko, T.C.3
Brattain, M.G.4
-
31
-
-
70449338760
-
Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation
-
Bornstein S., White R., Malkoski S., Oka M., Han G., Cleaver T., Reh D., Andersen P., Gross N., Olson S., Deng C., Lu S.L., Wang X.J. Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. J. Clin. Invest. 2009, 119:3408-3419.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3408-3419
-
-
Bornstein, S.1
White, R.2
Malkoski, S.3
Oka, M.4
Han, G.5
Cleaver, T.6
Reh, D.7
Andersen, P.8
Gross, N.9
Olson, S.10
Deng, C.11
Lu, S.L.12
Wang, X.J.13
-
32
-
-
33751311939
-
Inhibition of transforming growth factor-beta signaling in human cancer: targeting a tumor suppressor network as a therapeutic strategy
-
Biswas S., Criswell T.L., Wang S.E., Arteaga C.L. Inhibition of transforming growth factor-beta signaling in human cancer: targeting a tumor suppressor network as a therapeutic strategy. Clin. Cancer Res. 2006, 12:4142-4146.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4142-4146
-
-
Biswas, S.1
Criswell, T.L.2
Wang, S.E.3
Arteaga, C.L.4
|