-
1
-
-
0030602833
-
Size control: The regulation of cell numbers in animal development
-
M.C. Raff Size control: The regulation of cell numbers in animal development Cell 86 1996 173 175
-
(1996)
Cell
, vol.86
, pp. 173-175
-
-
Raff, M.C.1
-
2
-
-
0029993331
-
Apoptosis and the maintenance of homeostasis in the immune system
-
B.A. Osborne Apoptosis and the maintenance of homeostasis in the immune system Curr. Opin. Immunol. 8 1996 245 254
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 245-254
-
-
Osborne, B.A.1
-
3
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
C.B. Thompson Apoptosis in the pathogenesis and treatment of disease Science 267 1995 1456 1462
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
4
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
2942622030
-
Nuclear translocation of cytochrome c during apoptosis
-
E.K.A. Nur, S.R. Gross, Z. Pan, Z. Balklava, J. Ma, and L.F. Liu Nuclear translocation of cytochrome c during apoptosis J. Biol. Chem. 279 2004 24911 24914
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24911-24914
-
-
Nur, E.K.A.1
Gross, S.R.2
Pan, Z.3
Balklava, Z.4
Ma, J.5
Liu, L.F.6
-
6
-
-
0024394417
-
Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases
-
U.T. Ruegg, and G.M. Burgess Staurosporine, K-252 and UCN-01: Potent but nonspecific inhibitors of protein kinases Trends Pharmacol. Sci. 10 1989 218 220
-
(1989)
Trends Pharmacol. Sci.
, vol.10
, pp. 218-220
-
-
Ruegg, U.T.1
Burgess, G.M.2
-
7
-
-
0028866845
-
Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2
-
F. Meggio, A. Donella Deaana, M. Ruzzene, A.M. Brunati, L. Cesaro, B. Guerra, T. Meyer, H. Mett, D. Fabbro, and P. Furet Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2 Eur. J. Biochem. 234 1995 317 322
-
(1995)
Eur. J. Biochem.
, vol.234
, pp. 317-322
-
-
Meggio, F.1
Donella Deaana, A.2
Ruzzene, M.3
Brunati, A.M.4
Cesaro, L.5
Guerra, B.6
Meyer, T.7
Mett, H.8
Fabbro, D.9
Furet, P.10
-
8
-
-
0025998841
-
Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors
-
T. Tamaoki Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors Methods Enzymol. 201 1991 340 347
-
(1991)
Methods Enzymol.
, vol.201
, pp. 340-347
-
-
Tamaoki, T.1
-
9
-
-
0025871634
-
Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle
-
H.A. Crissman, D. Gadbois, R.A. Tobey, and E.M. Bradbury Transformed mammalian cells are deficient in kinase-mediated control of progression through the G1 phase of the cell cycle Proc. Natl. Acad. Sci. USA 88 1991 7580 7584
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7580-7584
-
-
Crissman, H.A.1
Gadbois, D.2
Tobey, R.A.3
Bradbury, E.M.4
-
10
-
-
0026501878
-
Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes
-
S. Bruno, B. Ardelt, J.S. Skierski, F. Traganos, and Z. Darzynkiewicz Different effects of staurosporine, an inhibitor of protein kinases, on the cell cycle and chromatin structure of normal and leukemic lymphocytes Cancer Res. 52 1992 470 473
-
(1992)
Cancer Res.
, vol.52
, pp. 470-473
-
-
Bruno, S.1
Ardelt, B.2
Skierski, J.S.3
Traganos, F.4
Darzynkiewicz, Z.5
-
11
-
-
0023853878
-
Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds
-
T. Okazaki, Y. Kato, T. Mochizuki, M. Tashima, H. Sawada, and H. Uchino Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds Exp. Hematol. 16 1988 42 48
-
(1988)
Exp. Hematol.
, vol.16
, pp. 42-48
-
-
Okazaki, T.1
Kato, Y.2
Mochizuki, T.3
Tashima, M.4
Sawada, H.5
Uchino, H.6
-
12
-
-
0026217135
-
Effects of protein kinase a and calcium/phospholipid-dependent kinase modulators in the process of HL-60 cell differentiation: Their opposite effects between HL-60 cell and K-562 cell differentiation
-
T. Okuda, H. Sawada, Y. Kato, Y. Yumoto, K. Ogawa, T. Tashima, and M. Okuma Effects of protein kinase A and calcium/phospholipid-dependent kinase modulators in the process of HL-60 cell differentiation: Their opposite effects between HL-60 cell and K-562 cell differentiation Cell Growth Differ. 2 1991 415 420
-
(1991)
Cell Growth Differ.
, vol.2
, pp. 415-420
-
-
Okuda, T.1
Sawada, H.2
Kato, Y.3
Yumoto, Y.4
Ogawa, K.5
Tashima, T.6
Okuma, M.7
-
13
-
-
0025651192
-
Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporine
-
G.K. Schwartz, S. Redwood, T. Ohnuma, J.F. Holland, M.J. Droller, and B.C. Liu Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporine J. Natl. Cancer Inst. 82 1990 1753 1756
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1753-1756
-
-
Schwartz, G.K.1
Redwood, S.2
Ohnuma, T.3
Holland, J.F.4
Droller, M.J.5
Liu, B.C.6
-
14
-
-
0034658350
-
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2
-
M. Haraguchi, S. Torii, S. Matsuzawa, Z. Xie, S. Kitada, S. Krajewski, H. Yoshida, T.W. Mak, and J.C. Reed Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2 J. Exp. Med. 191 2000 1709 1720
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1709-1720
-
-
Haraguchi, M.1
Torii, S.2
Matsuzawa, S.3
Xie, Z.4
Kitada, S.5
Krajewski, S.6
Yoshida, H.7
Mak, T.W.8
Reed, J.C.9
-
15
-
-
0033800260
-
Protein kinayse C inhibitor and irradiation-induced apoptosis: Relevance of the cytochrome c-mediated caspase-9 death pathway
-
S. Rocha, M. Soengas, S.W. Lowe, C. Glanzmann, D. Fabbro, K. Winterhalter, S. Bodis, and M. Pruschy Protein kinayse C inhibitor and irradiation-induced apoptosis: Relevance of the cytochrome c-mediated caspase-9 death pathway Cell Growth Differ. 11 2000 491 499
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 491-499
-
-
Rocha, S.1
Soengas, M.2
Lowe, S.W.3
Glanzmann, C.4
Fabbro, D.5
Winterhalter, K.6
Bodis, S.7
Pruschy, M.8
-
16
-
-
0036798144
-
Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis
-
J. Kabir, M. Lobo, and I. Zachary Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis Biochem. J. 367 2002 145 155
-
(2002)
Biochem. J.
, vol.367
, pp. 145-155
-
-
Kabir, J.1
Lobo, M.2
Zachary, I.3
-
17
-
-
0030963602
-
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
-
Y.T. Hsu, K.G. Wolter, and R.J. Youle Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis Proc. Natl. Acad. Sci. USA 94 1997 3668 3672
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3668-3672
-
-
Hsu, Y.T.1
Wolter, K.G.2
Youle, R.J.3
-
18
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
K.G. Wolter, Y.T. Hsu, C.L. Smith, A. Nechushtan, X.G. Xi, and R.J. Youle Movement of Bax from the cytosol to mitochondria during apoptosis J. Cell Biol. 139 1997 1281 1292
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
G X. Xi5
Youle, R.J.6
-
19
-
-
0034866507
-
Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential
-
S.S. Smaili, Y.T. Hsu, K.M. Sanders, J.T. Russell, and R.J. Youle Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential Cell Death Differ. 8 2001 909 920
-
(2001)
Cell Death Differ.
, vol.8
, pp. 909-920
-
-
Smaili, S.S.1
Hsu, Y.T.2
Sanders, K.M.3
Russell, J.T.4
Youle, R.J.5
-
20
-
-
0035866785
-
Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine
-
M. Tafani, D. Minchenko, A. Serroni, and J.L. Farber Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine Cancer Res. 61 2001 2459 2466
-
(2001)
Cancer Res.
, vol.61
, pp. 2459-2466
-
-
Tafani, M.1
Minchenko, D.2
Serroni, A.3
Farber, J.L.4
-
21
-
-
0034737736
-
Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis
-
D. Tang, J.M. Lahti, and V.J. Kidd Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis J. Biol. Chem. 275 2000 9303 9307
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9303-9307
-
-
Tang, D.1
Lahti, J.M.2
Kidd, V.J.3
-
22
-
-
0035826163
-
Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation
-
A. Stepczynska, K. Lauber, I.H. Engels, O. Janssen, D. Kabelitz, S. Wesselborg, and K. Schulze-Osthoff Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation Oncogene 20 2001 1193 1202
-
(2001)
Oncogene
, vol.20
, pp. 1193-1202
-
-
Stepczynska, A.1
Lauber, K.2
Engels, I.H.3
Janssen, O.4
Kabelitz, D.5
Wesselborg, S.6
Schulze-Osthoff, K.7
-
23
-
-
0026769457
-
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1
-
F.A. Oberhammer, M. Pavelka, S. Sharma, R. Tiefenbacher, A.F. Purchio, W. Bursch, and R. Schulte-Hermann Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1 Proc. Natl. Acad. Sci. USA 89 1992 5408 5412
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5408-5412
-
-
Oberhammer, F.A.1
Pavelka, M.2
Sharma, S.3
Tiefenbacher, R.4
Purchio, A.F.5
Bursch, W.6
Schulte-Hermann, R.7
-
24
-
-
0029583937
-
Role of transforming growth factor beta 1 on hepatic regeneration and apoptosis in liver diseases
-
S. Takiya, T. Tagaya, K. Takahashi, H. Kawashima, M. Kamiya, Y. Fukuzawa, S. Kobayashi, A. Fukatsu, K. Katoh, and S. Kakumu Role of transforming growth factor beta 1 on hepatic regeneration and apoptosis in liver diseases J. Clin. Pathol. 48 1995 1093 1097
-
(1995)
J. Clin. Pathol.
, vol.48
, pp. 1093-1097
-
-
Takiya, S.1
Tagaya, T.2
Takahashi, K.3
Kawashima, H.4
Kamiya, M.5
Fukuzawa, Y.6
Kobayashi, S.7
Fukatsu, A.8
Katoh, K.9
Kakumu, S.10
-
25
-
-
0030752438
-
Involvement of caspase family proteases in transforming growth factor-beta-induced apoptosis
-
R.H. Chen, and T.Y. Chang Involvement of caspase family proteases in transforming growth factor-beta-induced apoptosis Cell Growth Differ. 8 1997 821 827
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 821-827
-
-
Chen, R.H.1
Chang, T.Y.2
-
26
-
-
0029806099
-
Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines
-
A.Y. Hsing, K. Kadomatsu, M.J. Bonham, and D. Danielpour Regulation of apoptosis induced by transforming growth factor-beta1 in nontumorigenic rat prostatic epithelial cell lines Cancer Res. 56 1996 5146 5149
-
(1996)
Cancer Res.
, vol.56
, pp. 5146-5149
-
-
Hsing, A.Y.1
Kadomatsu, K.2
Bonham, M.J.3
Danielpour, D.4
-
27
-
-
0028846740
-
Characterization of transforming growth factor-beta 1 induced apoptosis in normal human B cells and lymphoma B cell lines
-
N. Chaouchi, L. Arvanitakis, M.T. Auffredou, D.A. Blanchard, A. Vazquez, and S. Sharma Characterization of transforming growth factor-beta 1 induced apoptosis in normal human B cells and lymphoma B cell lines Oncogene 11 1995 1615 1622
-
(1995)
Oncogene
, vol.11
, pp. 1615-1622
-
-
Chaouchi, N.1
Arvanitakis, L.2
Auffredou, M.T.3
Blanchard, D.A.4
Vazquez, A.5
Sharma, S.6
-
28
-
-
0030198199
-
TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: Transcriptional activation of I kappa B alpha
-
M. Arsura, M. Wu, and G.E. Sonenshein TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: Transcriptional activation of I kappa B alpha Immunity 5 1996 31 40
-
(1996)
Immunity
, vol.5
, pp. 31-40
-
-
Arsura, M.1
Wu, M.2
Sonenshein, G.E.3
-
29
-
-
0038043227
-
Smad3 potentiates transforming growth factor beta (TGF-beta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes
-
G.M. Wildey, S. Patil, and P.H. Howe Smad3 potentiates transforming growth factor beta (TGF-beta)-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes J. Biol. Chem. 278 2003 18069 18077
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18069-18077
-
-
Wildey, G.M.1
Patil, S.2
Howe, P.H.3
-
30
-
-
0034671532
-
Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells
-
J.M. Francis, C.M. Heyworth, E. Spooncer, A. Pierce, T.M. Dexter, and A.D. Whetton Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells J. Biol. Chem. 275 2000 39137 39145
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39137-39145
-
-
Francis, J.M.1
Heyworth, C.M.2
Spooncer, E.3
Pierce, A.4
Dexter, T.M.5
Whetton, A.D.6
-
31
-
-
0034680863
-
Critical role of Smads and AP-1 complex in transforming growth factor-beta-dependent apoptosis
-
Y. Yamamura, X. Hua, S. Bergelson, and H.F. Lodish Critical role of Smads and AP-1 complex in transforming growth factor-beta-dependent apoptosis J. Biol. Chem. 275 2000 36295 36302
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36295-36302
-
-
Yamamura, Y.1
Hua, X.2
Bergelson, S.3
Lodish, H.F.4
-
32
-
-
0034624057
-
Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta-induced growth inhibition and apoptosis
-
S. Patil, G. Wildey, T.L. Brown, L. Choy, R. Derynck, and P.H. Howe Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta-induced growth inhibition and apoptosis J. Biol. Chem. 275 2000 38363 38370
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38363-38370
-
-
Patil, S.1
Wildey, G.2
Brown, T.L.3
Choy, L.4
Derynck, R.5
Howe, P.H.6
-
33
-
-
0036173901
-
Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells
-
B.C. Kim, M. Mamura, K.S. Choi, B. Calabretta, and S.J. Kim Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells Mol. Cell. Biol. 22 2002 1369 1378
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1369-1378
-
-
Kim, B.C.1
Mamura, M.2
Choi, K.S.3
Calabretta, B.4
Kim, S.J.5
-
34
-
-
0036902409
-
Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP
-
H. Valderrama-Carvajal, E. Cocolakis, A. Lacerte, E.H. Lee, G. Krystal, S. Ali, and J.J. Lebrun Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP Nat. Cell Biol. 4 2002 963 969
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 963-969
-
-
Valderrama-Carvajal, H.1
Cocolakis, E.2
Lacerte, A.3
Lee, E.H.4
Krystal, G.5
Ali, S.6
Lebrun, J.J.7
-
35
-
-
0034906821
-
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation
-
R. Perlman, W.P. Schiemann, M.W. Brooks, H.F. Lodish, and R.A. Weinberg TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation Nat. Cell Biol. 3 2001 708 714
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 708-714
-
-
Perlman, R.1
Schiemann, W.P.2
Brooks, M.W.3
Lodish, H.F.4
Weinberg, R.A.5
-
36
-
-
0037849935
-
Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling
-
C. Dai, J. Yang, and Y. Liu Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling J. Biol. Chem. 278 2003 12537 12545
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12537-12545
-
-
Dai, C.1
Yang, J.2
Liu, Y.3
-
37
-
-
0034747307
-
TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures
-
Y. Zhu, B. Ahlemeyer, E. Bauerbach, and J. Krieglstein TGF-beta1 inhibits caspase-3 activation and neuronal apoptosis in rat hippocampal cultures Neurochem. Int. 38 2001 227 235
-
(2001)
Neurochem. Int.
, vol.38
, pp. 227-235
-
-
Zhu, Y.1
Ahlemeyer, B.2
Bauerbach, E.3
Krieglstein, J.4
-
38
-
-
0037095746
-
Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage
-
Y. Zhu, G.Y. Yang, B. Ahlemeyer, L. Pang, X.M. Che, C. Culmsee, S. Klumpp, and J. Krieglstein Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage J. Neurosci. 22 2002 3898 3909
-
(2002)
J. Neurosci.
, vol.22
, pp. 3898-3909
-
-
Zhu, Y.1
Yang, G.Y.2
Ahlemeyer, B.3
Pang, L.4
Che, X.M.5
Culmsee, C.6
Klumpp, S.7
Krieglstein, J.8
-
39
-
-
0034805386
-
Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death
-
N.S. Chang Hyaluronidase activation of c-Jun N-terminal kinase is necessary for protection of L929 fibrosarcoma cells from staurosporine-mediated cell death Biochem. Biophys. Res. Commun. 283 2001 278 286
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 278-286
-
-
Chang, N.S.1
-
40
-
-
0042441979
-
Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways
-
W. Jia, C. Yu, M. Rahmani, G. Krystal, E.A. Sausville, P. Dent, and S. Grant Synergistic antileukemic interactions between 17-AAG and UCN-01 involve interruption of RAF/MEK- and AKT-related pathways Blood 102 2003 1824 1832
-
(2003)
Blood
, vol.102
, pp. 1824-1832
-
-
Jia, W.1
Yu, C.2
Rahmani, M.3
Krystal, G.4
Sausville, E.A.5
Dent, P.6
Grant, S.7
-
41
-
-
0035992286
-
Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition
-
J.P. Mackeigan, D.J. Taxman, D. Hunter, H.S. Earp III, L.M. Graves, and J.P. Ting Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition Clin. Cancer Res. 8 2002 2091 2099
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 2091-2099
-
-
MacKeigan, J.P.1
Taxman, D.J.2
Hunter, D.3
Earp III, H.S.4
Graves, L.M.5
Ting, J.P.6
-
42
-
-
0036839524
-
Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism
-
Y. Dai, T.H. Landowski, S.T. Rosen, P. Dent, and S. Grant Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism Blood 100 2002 3333 3343
-
(2002)
Blood
, vol.100
, pp. 3333-3343
-
-
Dai, Y.1
Landowski, T.H.2
Rosen, S.T.3
Dent, P.4
Grant, S.5
-
43
-
-
0035393498
-
Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells
-
Y. Dai, C. Yu, V. Singh, L. Tang, Z. Wang, R. Mcinistry, P. Dent, and S. Grant Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells Cancer Res. 61 2001 5106 5115
-
(2001)
Cancer Res.
, vol.61
, pp. 5106-5115
-
-
Dai, Y.1
Yu, C.2
Singh, V.3
Tang, L.4
Wang, Z.5
McInistry, R.6
Dent, P.7
Grant, S.8
-
44
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
D.P. Brazil, and B.A. Hemmings Ten years of protein kinase B signalling: A hard Akt to follow Trends Biochem. Sci. 26 2001 657 664
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
45
-
-
2342647439
-
PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3
-
I. Remy, A. Montmarquette, and S.W. Michnick PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3 Nat. Cell Biol. 6 2004 358 365
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 358-365
-
-
Remy, I.1
Montmarquette, A.2
Michnick, S.W.3
-
46
-
-
2342471301
-
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis
-
A.R. Conery, Y. Cao, E.A. Thompson, C.M. Townsend Jr., T.C. Ko, and K. Luo Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis Nat. Cell Biol. 6 2004 366 372
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 366-372
-
-
Conery, A.R.1
Cao, Y.2
Thompson, E.A.3
Townsend Jr., C.M.4
Ko, T.C.5
Luo, K.6
-
47
-
-
0037034928
-
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
-
S. Sato, N. Fujita, and T. Tsuruo Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine) Oncogene 21 2002 1727 1738
-
(2002)
Oncogene
, vol.21
, pp. 1727-1738
-
-
Sato, S.1
Fujita, N.2
Tsuruo, T.3
-
48
-
-
0032718990
-
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation
-
M. Fujii, K. Takeda, T. Imamura, H. Aoki, T.K. Sampath, S. Enomoto, M. Kawabata, M. Kato, H. Ichijo, and K. Miyazono Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation Mol. Biol. Cell 10 1999 3801 3813
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3801-3813
-
-
Fujii, M.1
Takeda, K.2
Imamura, T.3
Aoki, H.4
Sampath, T.K.5
Enomoto, S.6
Kawabata, M.7
Kato, M.8
Ichijo, H.9
Miyazono, K.10
-
49
-
-
0036134975
-
Suppression of Akt signaling induces Fas ligand expression: Involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation
-
T. Suhara, H.S. Kim, L.A. Kirshenbaum, and K. Walsh Suppression of Akt signaling induces Fas ligand expression: Involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation Mol. Cell. Biol. 22 2002 680 691
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 680-691
-
-
Suhara, T.1
Kim, H.S.2
Kirshenbaum, L.A.3
Walsh, K.4
-
50
-
-
0035117460
-
Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): Caspase-8 is required for TRAIL-induced apoptosis
-
D.W. Seol, J. Li, M.H. Seol, S.Y. Park, R.V. Talanian, and T.R. Billiar Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): Caspase-8 is required for TRAIL-induced apoptosis Cancer Res. 61 2001 1138 1143
-
(2001)
Cancer Res.
, vol.61
, pp. 1138-1143
-
-
Seol, D.W.1
Li, J.2
Seol, M.H.3
Park, S.Y.4
Talanian, R.V.5
Billiar, T.R.6
-
51
-
-
0032549670
-
Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
-
C. Widmann, S. Gibson, and G.L. Johnson Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals J. Biol. Chem. 273 1998 7141 7147
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7141-7147
-
-
Widmann, C.1
Gibson, S.2
Johnson, G.L.3
-
52
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Z. Xia, M. Dickens, J. Raingeaud, R.J. Davis, and M.E. Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1995 1326 1331
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
53
-
-
0034708456
-
The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons
-
L. Xue, J.H. Murray, and A.M. Tolkovsky The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons J. Biol. Chem. 275 2000 8817 8824
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8817-8824
-
-
Xue, L.1
Murray, J.H.2
Tolkovsky, A.M.3
-
54
-
-
0034630186
-
Serine/threonine protein kinases and apoptosis
-
T.G. Cross, D. Scheel-Toellner, N.V. Henriquez, E. Deacon, M. Salmon, and J.M. Lord Serine/threonine protein kinases and apoptosis Exp. Cell Res. 256 2000 34 41
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 34-41
-
-
Cross, T.G.1
Scheel-Toellner, D.2
Henriquez, N.V.3
Deacon, E.4
Salmon, M.5
Lord, J.M.6
-
55
-
-
0036136943
-
Mechanisms of TGF-beta-mediated apoptosis
-
N. Schuster, and K. Krieglstein Mechanisms of TGF-beta-mediated apoptosis Cell Tissue Res. 307 2002 1 14
-
(2002)
Cell Tissue Res.
, vol.307
, pp. 1-14
-
-
Schuster, N.1
Krieglstein, K.2
|