Poly-l-arginine-induced internalization of tight junction proteins increases the paracellular permeability of the caco-2 cell monolayer to hydrophilic macromolecules

Biological and Pharmaceutical Bulletin

Volumn 36, Issue 3, 2013, Pages 432-441

  Yamaki, Tsutomu ^a   Ohtake, Kazuo ^a   Ichikawa, Keiko ^a   Uchida, Masaki ^a   Uchida, Hiroyuki ^a   Ohshima, Shinji ^a   Juni, Kazuhiko ^a   Kobayashi, Jun ^a   Morimoto, Yasunori ^a   Natsume, Hideshi ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

Absorption enhancer; Drug delivery; Hydrophilic macromolecule; Poly l arginine; Tight junction

Indexed keywords

CLAUDIN 4; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; OCCLUDIN; POLYARGININE; PROTEIN ZO1; TIGHT JUNCTION PROTEIN; TRICELLULIN;

ARTICLE; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CELL VIABILITY; CONTROLLED STUDY; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR SPACE; PROTEIN EXPRESSION; TRANSEPITHELIAL ELECTRICAL RESISTANCE;

CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; ELECTRIC IMPEDANCE; HUMANS; MICROSCOPY, FLUORESCENCE; PEPTIDES; TIGHT JUNCTION PROTEINS;

EID: 84875499547     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00878     Document Type: Article

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