Improved nasal absorption of drugs using poly-L-arginine: Effects of concentration and molecular weight of poly-L-arginine on the nasal absorption of fluorescein isothiocyanate-dextran in rats

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 52, Issue 1, 2001, Pages 21-30

  Miyamoto, Misao ^a   Natsume, Hideshi ^b   Iwata, Satoko ^b   Ohtake, Kazuo ^b   Yamaguchi, Masatoshi ^c   Kobayashi, Daisuke ^b   Sugibayashi, Kenji ^b   Yamashina, Motoaki ^d   Morimoto, Yasunori ^b  

^a NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

^b JOSAI UNIVERSITY   (Japan)

^c Prefectural Kakizaki Hospital   (Japan)

^d Iruma Heart Hospital   (Japan)

Author keywords

Absorption enhancer; Fluorescein isothiocyanate labeled dextran; Molecular weight; Nasal delivery; Poly L arginine

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE DEXTRAN; PENETRATION ENHANCING AGENT; POLYARGININE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; HISTOLOGY; MALE; MEMBRANE DAMAGE; MOLECULAR WEIGHT; NONHUMAN; NOSE MUCOSA; RAT;

ABSORPTION; ANIMALS; DEXTRANS; FLUORESCEIN-5-ISOTHIOCYANATE; MALE; MOLECULAR WEIGHT; NASAL MUCOSA; PEPTIDES; RATS; RATS, WISTAR;

EID: 0034962912     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(01)00149-7     Document Type: Article

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