메뉴 건너뛰기




Volumn 3, Issue 5-6, 2012, Pages 334-340

Roles for Crk in Cancer Metastasis and Invasion

Author keywords

Crk adaptor protein; human cancer; invasion; metastasis

Indexed keywords

ABELSON KINASE; ADAPTOR PROTEIN; CATENIN; CRK ASSOCIATED SUBSTRATE PROTEIN; CT10 REGULATOR OF KINASE PROTEIN; DASATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PAXILLIN; PROTEIN P120; PROTEIN TYROSINE KINASE; SCAFFOLD PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

EID: 84875493705     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: 10.1177/1947601912458687     Document Type: Article
Times cited : (40)

References (53)
  • 1
    • 0023864050 scopus 로고
    • A novel viral oncogene with structural similarity to phospholipase C
    • Mayer BJ,Hamaguchi M,Hanafusa H.A novel viral oncogene with structural similarity to phospholipase C.Nature. 1988;332:272-5.
    • (1988) Nature , vol.332 , pp. 272-275
    • Mayer, B.J.1    Hamaguchi, M.2    Hanafusa, H.3
  • 2
  • 3
    • 0026895954 scopus 로고
    • The product of the cellular crk gene consists primarily of SH2 and SH3 regions
    • Reichman CT,Mayer BJ,Keshav S,Hanafusa H.The product of the cellular crk gene consists primarily of SH2 and SH3 regions.Cell Growth Differ. 1992;3:451-60.
    • (1992) Cell Growth Differ , vol.3 , pp. 451-460
    • Reichman, C.T.1    Mayer, B.J.2    Keshav, S.3    Hanafusa, H.4
  • 4
    • 0027179910 scopus 로고
    • Isolation and chromosomal localization of CRKL, a human crk-like gene
    • ten Hoeve J,Morris C,Heisterkamp N,Groffen J.Isolation and chromosomal localization of CRKL, a human crk-like gene.Oncogene. 1993;8:2469-74.
    • (1993) Oncogene , vol.8 , pp. 2469-2474
    • ten Hoeve, J.1    Morris, C.2    Heisterkamp, N.3    Groffen, J.4
  • 5
    • 33746220057 scopus 로고    scopus 로고
    • Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II
    • Muralidharan V,Dutta K,Cho J, et al.Solution structure and folding characteristics of the C-terminal SH3 domain of c-Crk-II.Biochemistry. 2006;45:8874-84.
    • (2006) Biochemistry , vol.45 , pp. 8874-8884
    • Muralidharan, V.1    Dutta, K.2    Cho, J.3
  • 6
    • 28744435281 scopus 로고    scopus 로고
    • Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain
    • Reichman C,Singh K,Liu Y,Singh S,Li H,Fajardo JE, et al.Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.Oncogene. 2005;24:8187-99.
    • (2005) Oncogene , vol.24 , pp. 8187-8199
    • Reichman, C.1    Singh, K.2    Liu, Y.3    Singh, S.4    Li, H.5    Fajardo, J.E.6
  • 7
    • 0042567278 scopus 로고    scopus 로고
    • CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins
    • Prosser S,Sorokina E,Pratt P,Sorokin A.CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteins.Oncogene. 2003;22:4799-806.
    • (2003) Oncogene , vol.22 , pp. 4799-4806
    • Prosser, S.1    Sorokina, E.2    Pratt, P.3    Sorokin, A.4
  • 8
    • 77949828806 scopus 로고    scopus 로고
    • Crk and CrkL adaptor proteins: networks for physiological and pathological signaling
    • Birge RB,Kalodimos C,Inagaki F,Tanaka S.Crk and CrkL adaptor proteins: networks for physiological and pathological signaling.Cell Commun Signal. 2009;7:13.
    • (2009) Cell Commun Signal , vol.7 , pp. 13
    • Birge, R.B.1    Kalodimos, C.2    Inagaki, F.3    Tanaka, S.4
  • 9
    • 79960045948 scopus 로고    scopus 로고
    • Emerging roles for crk in human cancer
    • Sriram G,Birge RB.Emerging roles for crk in human cancer.Genes Cancer. 2010;1:1132-9.
    • (2010) Genes Cancer , vol.1 , pp. 1132-1139
    • Sriram, G.1    Birge, R.B.2
  • 10
    • 33745135776 scopus 로고    scopus 로고
    • Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS
    • Linghu H,Tsuda M,Makino Y, et al.Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS.Oncogene. 2006;25:3547-56.
    • (2006) Oncogene , vol.25 , pp. 3547-3556
    • Linghu, H.1    Tsuda, M.2    Makino, Y.3
  • 11
    • 33746888255 scopus 로고    scopus 로고
    • Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines
    • Watanabe T,Tsuda M,Makino Y, et al.Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines.Mol Cancer Res. 2006;4:499-510.
    • (2006) Mol Cancer Res , vol.4 , pp. 499-510
    • Watanabe, T.1    Tsuda, M.2    Makino, Y.3
  • 12
    • 34548580690 scopus 로고    scopus 로고
    • Signaling adaptor protein Crk is indispensable for malignant feature of glioblastoma cell line KMG4
    • Wang L,Tabu K,Kimura T, et al.Signaling adaptor protein Crk is indispensable for malignant feature of glioblastoma cell line KMG4.Biochem Biophys Res Commun. 2007;362:976-81.
    • (2007) Biochem Biophys Res Commun , vol.362 , pp. 976-981
    • Wang, L.1    Tabu, K.2    Kimura, T.3
  • 13
    • 48949115082 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines
    • Crawford M,Brawner E,Batte K, et al.MicroRNA-126 inhibits invasion in non-small cell lung carcinoma cell lines.Biochem Biophys Res Commun. 2008;373:607-12.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 607-612
    • Crawford, M.1    Brawner, E.2    Batte, K.3
  • 14
    • 77956915352 scopus 로고    scopus 로고
    • miR-126 functions as a tumour suppressor in human gastric cancer
    • Feng RH,Chen XH,Yu YY, et al.miR-126 functions as a tumour suppressor in human gastric cancer.Cancer Letters. 2010;298:50-63.
    • (2010) Cancer Letters , vol.298 , pp. 50-63
    • Feng, R.H.1    Chen, X.H.2    Yu, Y.Y.3
  • 15
    • 8744262049 scopus 로고    scopus 로고
    • Crk associates with ERM proteins and promotes cell motility toward hyaluronic acid
    • Tsuda M,Makino Y,Iwahara T, et al.Crk associates with ERM proteins and promotes cell motility toward hyaluronic acid.J Biol Chem. 2004;279:46843-50.
    • (2004) J Biol Chem , vol.279 , pp. 46843-46850
    • Tsuda, M.1    Makino, Y.2    Iwahara, T.3
  • 17
    • 79952043247 scopus 로고    scopus 로고
    • Overexpression of CRKII increases migration and invasive potential in oral squamous cell carcinoma
    • Yamada S,Yanamoto S,Kawasaki G, et al.Overexpression of CRKII increases migration and invasive potential in oral squamous cell carcinoma.Cancer Letters. 2011;303:84-91.
    • (2011) Cancer Letters , vol.303 , pp. 84-91
    • Yamada, S.1    Yanamoto, S.2    Kawasaki, G.3
  • 18
    • 70349758510 scopus 로고    scopus 로고
    • Src kinases as therapeutic targets for cancer
    • Kim LC,Song L,Haura EB.Src kinases as therapeutic targets for cancer.Nat Rev Clin Oncol. 2009;6:587-95.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 587-595
    • Kim, L.C.1    Song, L.2    Haura, E.B.3
  • 19
    • 84865182966 scopus 로고    scopus 로고
    • EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation
    • Huang M,Anand S,Murphy EA, et al.EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation.Oncogene. 2011;:.
    • (2011) Oncogene
    • Huang, M.1    Anand, S.2    Murphy, E.A.3
  • 20
    • 66149192409 scopus 로고    scopus 로고
    • Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo
    • Hingorani P,Zhang WD,Gorlick R,Kolb EA.Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo.Clin Cancer Res. 2009;15:3416-22.
    • (2009) Clin Cancer Res , vol.15 , pp. 3416-3422
    • Hingorani, P.1    Zhang, W.D.2    Gorlick, R.3    Kolb, E.A.4
  • 21
    • 67649101451 scopus 로고    scopus 로고
    • Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration
    • Watanabe T,Tsuda M,Makino Y, et al.Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration.Cell Res. 2009;19:638-50.
    • (2009) Cell Res , vol.19 , pp. 638-650
    • Watanabe, T.1    Tsuda, M.2    Makino, Y.3
  • 22
    • 56449100212 scopus 로고    scopus 로고
    • Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells
    • Buettner R,Mesa T,Vultur A,Lee F,Jove R.Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells.Mol Cancer Res. 2008;6:1766-74.
    • (2008) Mol Cancer Res , vol.6 , pp. 1766-1774
    • Buettner, R.1    Mesa, T.2    Vultur, A.3    Lee, F.4    Jove, R.5
  • 23
    • 77950605242 scopus 로고    scopus 로고
    • CAS proteins in normal and pathological cell growth control
    • Tikhmyanova N,Little JL,Golemis EA.CAS proteins in normal and pathological cell growth control.Cell Mol Life Sci. 2010;67:1025-48.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1025-1048
    • Tikhmyanova, N.1    Little, J.L.2    Golemis, E.A.3
  • 24
    • 2342495279 scopus 로고    scopus 로고
    • A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling
    • Kirsch K,Kensinger M,Hanafusa H,August A.A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling.BMC Cell Biol. 2002;3:18.
    • (2002) BMC Cell Biol , vol.3 , pp. 18
    • Kirsch, K.1    Kensinger, M.2    Hanafusa, H.3    August, A.4
  • 25
    • 21344443681 scopus 로고    scopus 로고
    • Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of Src-transformed cells
    • Brabek J,Constancio SS,Siesser PF,Shin NY,Pozzi A,Hanks SK.Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of Src-transformed cells.Mol Cancer Res. 2005;3:307-15.
    • (2005) Mol Cancer Res , vol.3 , pp. 307-315
    • Brabek, J.1    Constancio, S.S.2    Siesser, P.F.3    Shin, N.Y.4    Pozzi, A.5    Hanks, S.K.6
  • 26
    • 0035474419 scopus 로고    scopus 로고
    • Functions of the adapter protein Cas: signal convergence and the determination of cellular responses
    • Bouton AH,Riggins RB,Bruce-Staskal PJ.Functions of the adapter protein Cas: signal convergence and the determination of cellular responses.Oncogene. 2001;20:6448-58.
    • (2001) Oncogene , vol.20 , pp. 6448-6458
    • Bouton, A.H.1    Riggins, R.B.2    Bruce-Staskal, P.J.3
  • 27
    • 3042717667 scopus 로고    scopus 로고
    • Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold
    • Chodniewicz D,Klemke RL.Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.Biochim Biophys Acta Mol Cell Res. 2004;1692:63-76.
    • (2004) Biochim Biophys Acta Mol Cell Res , vol.1692 , pp. 63-76
    • Chodniewicz, D.1    Klemke, R.L.2
  • 28
    • 0038505214 scopus 로고    scopus 로고
    • Cytoplasmic c-Abl provides a molecular "rheostat" controlling carcinoma cell survival and invasion
    • Kain KH,Gooch S,Klemke RL.Cytoplasmic c-Abl provides a molecular "rheostat" controlling carcinoma cell survival and invasion.Oncogene. 2003;22:6071-80.
    • (2003) Oncogene , vol.22 , pp. 6071-6080
    • Kain, K.H.1    Gooch, S.2    Klemke, R.L.3
  • 29
    • 44949179470 scopus 로고    scopus 로고
    • A novel Cas family member, HEPL, regulates FAK and cell spreading
    • Singh MK,Dadke D,Nicolas E, et al.A novel Cas family member, HEPL, regulates FAK and cell spreading.Mol Biol Cell. 2008;19:1627-36.
    • (2008) Mol Biol Cell , vol.19 , pp. 1627-1636
    • Singh, M.K.1    Dadke, D.2    Nicolas, E.3
  • 30
    • 4644285487 scopus 로고    scopus 로고
    • The prognostic value of BCAR1 in patients with primary breast cancer
    • Dorssers LC,Grebenchtchikov N,Brinkman A, et al.The prognostic value of BCAR1 in patients with primary breast cancer.Clin Cancer Res. 2004;10:6194-202.
    • (2004) Clin Cancer Res , vol.10 , pp. 6194-6202
    • Dorssers, L.C.1    Grebenchtchikov, N.2    Brinkman, A.3
  • 31
    • 0034684997 scopus 로고    scopus 로고
    • BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells
    • Brinkman A,van der Flier S,Kok EM,Dorssers LC.BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.J Natl Cancer Inst. 2000;92:112-20.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 112-120
    • Brinkman, A.1    van der Flier, S.2    Kok, E.M.3    Dorssers, L.C.4
  • 32
    • 0034707581 scopus 로고    scopus 로고
    • ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases
    • Spencer KS,Graus-Porta D,Leng J,Hynes NE,Klemke RL.ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases.J Cell Biol. 2000;148:385-97.
    • (2000) J Cell Biol , vol.148 , pp. 385-397
    • Spencer, K.S.1    Graus-Porta, D.2    Leng, J.3    Hynes, N.E.4    Klemke, R.L.5
  • 33
    • 33646422461 scopus 로고    scopus 로고
    • p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis
    • Cabodi S,Tinnirello A,Di Stefano P, et al.p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.Cancer Res. 2006;66:4672-80.
    • (2006) Cancer Res , vol.66 , pp. 4672-4680
    • Cabodi, S.1    Tinnirello, A.2    Di Stefano, P.3
  • 34
    • 84858047927 scopus 로고    scopus 로고
    • Regulation of p130(Cas)/BCAR1 expression in tamoxifen-sensitive and tamoxifen-resistant breast cancer cells by EGR1 and NAB2
    • Kumbrink J,Kirsch KH.Regulation of p130(Cas)/BCAR1 expression in tamoxifen-sensitive and tamoxifen-resistant breast cancer cells by EGR1 and NAB2.Neoplasia. 2012;14:108-20.
    • (2012) Neoplasia , vol.14 , pp. 108-120
    • Kumbrink, J.1    Kirsch, K.H.2
  • 35
    • 34547932906 scopus 로고    scopus 로고
    • AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology
    • Near RI,Zhang Y,Makkinje A,Vanden Borre P,Lerner A.AND-34/BCAR3 differs from other NSP homologs in induction of anti-estrogen resistance, cyclin D1 promoter activation and altered breast cancer cell morphology.J Cell Physiol. 2007;212:655-65.
    • (2007) J Cell Physiol , vol.212 , pp. 655-665
    • Near, R.I.1    Zhang, Y.2    Makkinje, A.3    Vanden Borre, P.4    Lerner, A.5
  • 36
    • 0041845239 scopus 로고    scopus 로고
    • Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3
    • Riggins RB,Quilliam LA,Bouton AH.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.J Biol Chem. 2003;278:28264-73.
    • (2003) J Biol Chem , vol.278 , pp. 28264-28273
    • Riggins, R.B.1    Quilliam, L.A.2    Bouton, A.H.3
  • 37
    • 78649464023 scopus 로고    scopus 로고
    • p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1
    • Tornillo G,Bisaro B,Camacho-Leal MeP.p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1.et al Eur J Cell Biol. 2011;90:237-48.
    • (2011) Eur J Cell Biol , vol.90 , pp. 237-248
    • Tornillo, G.1    Bisaro, B.2    Camacho-Leal Me, P.3
  • 38
    • 84860292363 scopus 로고    scopus 로고
    • p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells
    • Cunningham-Edmondson AC,Hanks SK.p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells.Breast Cancer (London). 2009;2009:39-52.
    • (2009) Breast Cancer (London) , vol.2009 , pp. 39-52
    • Cunningham-Edmondson, A.C.1    Hanks, S.K.2
  • 39
    • 66149098794 scopus 로고    scopus 로고
    • Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells
    • Soni S,Lin BT,August A,Nicholson RI,Kirsch KH.Expression of a phosphorylated p130(Cas) substrate domain attenuates the phosphatidylinositol 3-kinase/Akt survival pathway in tamoxifen resistant breast cancer cells.J Cell Biochem. 2009;107:364-75.
    • (2009) J Cell Biochem , vol.107 , pp. 364-375
    • Soni, S.1    Lin, B.T.2    August, A.3    Nicholson, R.I.4    Kirsch, K.H.5
  • 40
    • 71749099201 scopus 로고    scopus 로고
    • p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity
    • Wendt MK,Smith JA,Schiemann WP.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.J Biol Chem. 2009;284:34145-56.
    • (2009) J Biol Chem , vol.284 , pp. 34145-34156
    • Wendt, M.K.1    Smith, J.A.2    Schiemann, W.P.3
  • 41
    • 83055194551 scopus 로고    scopus 로고
    • CrkI and p130Cas complex regulates the migration and invasion of prostate cancer cells
    • Dai Y,Qi L,Zhang X,Li Y,Chen M,Zu X.CrkI and p130Cas complex regulates the migration and invasion of prostate cancer cells.Cell Biochem Funct. 2011;29:625-9.
    • (2011) Cell Biochem Funct , vol.29 , pp. 625-629
    • Dai, Y.1    Qi, L.2    Zhang, X.3    Li, Y.4    Chen, M.5    Zu, X.6
  • 42
    • 0033666291 scopus 로고    scopus 로고
    • Paxillin and focal adhesion signalling
    • Turner CE.Paxillin and focal adhesion signalling.Nat Cell Biol. 2000;2:E231-6.
    • (2000) Nat Cell Biol , vol.2
    • Turner, C.E.1
  • 43
    • 0027219262 scopus 로고
    • Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts
    • Birge RB,Fajardo JE,Reichman C, et al.Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.Mol Cell Biol. 1993;13:4648-56.
    • (1993) Mol Cell Biol , vol.13 , pp. 4648-4656
    • Birge, R.B.1    Fajardo, J.E.2    Reichman, C.3
  • 44
    • 0031897657 scopus 로고    scopus 로고
    • Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein
    • Altun-Gultekin ZF,Chandriani S,Bougeret C, et al.Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein.Mol Cell Biol. 1998;18:3044-58.
    • (1998) Mol Cell Biol , vol.18 , pp. 3044-3058
    • Altun-Gultekin, Z.F.1    Chandriani, S.2    Bougeret, C.3
  • 45
    • 23044500874 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma
    • Azuma K,Tanaka M,Uekita T, et al.Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma.Oncogene. 2005;24:4754-64.
    • (2005) Oncogene , vol.24 , pp. 4754-4764
    • Azuma, K.1    Tanaka, M.2    Uekita, T.3
  • 46
    • 77955241248 scopus 로고    scopus 로고
    • Paxillin expression levels are correlated with clinical stage and metastasis in salivary adenoid cystic carcinoma
    • Shi JN,Wang S,Zhao EY,Shi L,Xu X,Fang M.Paxillin expression levels are correlated with clinical stage and metastasis in salivary adenoid cystic carcinoma.J Oral Pathol Med. 2010;39:548-51.
    • (2010) J Oral Pathol Med , vol.39 , pp. 548-551
    • Shi, J.N.1    Wang, S.2    Zhao, E.Y.3    Shi, L.4    Xu, X.5    Fang, M.6
  • 47
    • 0942301172 scopus 로고    scopus 로고
    • Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
    • Fernandis AZ,Prasad A,Band H,Klosel R,Ganju RK.Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells.Oncogene. 2004;23:157-67.
    • (2004) Oncogene , vol.23 , pp. 157-167
    • Fernandis, A.Z.1    Prasad, A.2    Band, H.3    Klosel, R.4    Ganju, R.K.5
  • 48
    • 7244250167 scopus 로고    scopus 로고
    • Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells
    • Valles AM,Beuvin M,Boyer B.Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells.J Biol Chem. 2004;279:44490-6.
    • (2004) J Biol Chem , vol.279 , pp. 44490-44496
    • Valles, A.M.1    Beuvin, M.2    Boyer, B.3
  • 49
    • 84855926182 scopus 로고    scopus 로고
    • Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival
    • Zhao F,Siu MKY,Jiang LL, et al.Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival.Histopathology. 2011;59:1163-72.
    • (2011) Histopathology , vol.59 , pp. 1163-1172
    • Zhao, F.1    Siu, M.K.Y.2    Jiang, L.L.3
  • 50
    • 79955523891 scopus 로고    scopus 로고
    • c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells
    • Mortazavi F,Dubinett S,Rettig M.c-Crk proto-oncogene contributes to transcriptional repression of p120-catenin in non-small cell lung cancer cells.Clin Exp Metastasis. 2011;28:391-404.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 391-404
    • Mortazavi, F.1    Dubinett, S.2    Rettig, M.3
  • 51
    • 40549133440 scopus 로고    scopus 로고
    • Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases
    • Zandy NL,Pendergast AM.Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases.Cell Cycle. 2008;7:444-8.
    • (2008) Cell Cycle , vol.7 , pp. 444-448
    • Zandy, N.L.1    Pendergast, A.M.2
  • 52
    • 64049091850 scopus 로고    scopus 로고
    • A role for AP-1 in matrix metalloproteinase production and invadopodia formation of v-Crk-transformed cells
    • Hasegawa H,Senga T,Ito S,Iwamoto T,Hamaguchi M.A role for AP-1 in matrix metalloproteinase production and invadopodia formation of v-Crk-transformed cells.Exp Cell Res. 2009;315:1384-92.
    • (2009) Exp Cell Res , vol.315 , pp. 1384-1392
    • Hasegawa, H.1    Senga, T.2    Ito, S.3    Iwamoto, T.4    Hamaguchi, M.5
  • 53
    • 71249096888 scopus 로고    scopus 로고
    • NDRG1 and CRK-I/II are regulators of endothelial cell migration under intermittent hypoxia
    • Toffoli S,Delaive E,Dieu M,Feron O,Raes M,Michiels C.NDRG1 and CRK-I/II are regulators of endothelial cell migration under intermittent hypoxia.Angiogenesis. 2009;12:339-54.
    • (2009) Angiogenesis , vol.12 , pp. 339-354
    • Toffoli, S.1    Delaive, E.2    Dieu, M.3    Feron, O.4    Raes, M.5    Michiels, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.