Crk adaptor protein-induced phosphorylation of Gab1 on tyrosine 307 via Src is important for organization of focal adhesions and enhanced cell migration

Cell Research

Volumn 19, Issue 5, 2009, Pages 638-650

  Watanabe, Takuya ^a   Tsuda, Masumi ^a   Makino, Yoshinori ^a,c   Konstantinou, Tassos ^b   Nishihara, Hiroshi ^a   Majima, Tokifumi ^a   Minami, Akio ^a   Feller, Stephan M ^b   Tanaka, Shinya ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Crk; Gab1; Src; Tyrosine 307 phosphorylation

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; GAB1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C SRC; PROTEIN-TYROSINE KINASE C-SRC; PYRIMIDINE DERIVATIVE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROSINE;

ANIMAL; ARTICLE; CELL LINE; CELL MOTION; DOG; ENZYMOLOGY; FOCAL ADHESION; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; SRC HOMOLOGY DOMAIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; CELL MOVEMENT; DOGS; FOCAL ADHESIONS; HUMANS; MICE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-CRK; PYRIMIDINES; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 67649101451     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2009.40     Document Type: Article

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