Aqueous extract of paeonia lactiflora and paeoniflorin as aggregation reducers targeting chaperones in cell models of spinocerebellar ataxia 3

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Chang, Kuo Hsuan ^a   Chen, Wan Ling ^a   Lee, Li Ching ^b   Lin, Chih Hsin ^a   Kung, Pin Jui ^b   Lin, Te Hsien ^b   Wu, Yi Ci ^b   Wu, Yih Ru ^a   Chen, Yi Chun ^a   Lee Chen, Guey Jen ^b   Chen, Chiung Mei ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b NATIONAL TAIWAN NORMAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBIFLORIN; ATAXIN 3; CHAPERONE; GALLIC ACID; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; PAEONIA LACTIFLORA EXTRACT; PAEONIFLORIN; POLYGLUTAMINE; VORINOSTAT;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; NERVE CELL DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; SPINOCEREBELLAR DEGENERATION; UPREGULATION;

EID: 84875463971     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/471659     Document Type: Article

References (39)

1. Matilla-Dueñas A., Corral-Juan M., Volpini V., Sanchez I., The spinocerebellar ataxias: clinical aspects and molecular genetics. Advances in Experimental Medicine and Biology 2012 724 351 374 10.1007/978-1-4614-0653-2-27
2. Kawaguchi Y., Okamoto T., Taniwaki M., Aizawa M., Inoue M., Katayama S., Kawakami H., Nakamura S., Nishimura M., Akiguchi I., Kimura J., Narumiya S., Kakizuka A., CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nature Genetics 1994 8 3 221 228 2-s2.0-0028143527 10.1038/ng1194-221 (Pubitemid 24338732)
3. Orr H. T., Chung M. Y., Banfi S., Kwiatkowski T. J., Servadio A., Beaudet A. L., McCall A. E., Duvick L. A., Ranum L. P. W., Zoghbi H. Y., Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nature Genetics 1993 4 3 221 226 2-s2.0-0027164698 10.1038/ng0793-221 (Pubitemid 23205168)
4. Pulst S. M., Nechiporuk A., Nechiporuk T., Gispert S., Chen X. N., Lopes-Cendes I., Pearlman S., Starkman S., Orozco-Diaz G., Lunkes A., Dejong P., Rouleau G. A., Auburger G., Korenberg J. R., Figueroa C., Sahba S., Moderate expansion of a normally biallelic trinucleotide repeat in spinooerebellar ataxia type. Nature Genetics 1996 14 3 269 276 2-s2.0-0030292488
5. (1A)-voltage-dependent calcium channel. Nature Genetics 1997 15 1 62 69 2-s2.0-0031012399 10.1038/ng0197-62 (Pubitemid 27014951)
6. David G., Abbas N., Stevanin G., Dürr A., Yvert G., Cancel G., Weber C., Imbert G., Saudou F., Antoniou E., Drabkin H., Gemmill R., Giunti P., Benomar A., Wood N., Ruberg M., Agid Y., Mandel J. L., Brice A., Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nature Genetics 1997 17 1 65 70 2-s2.0-16944364511 10.1038/ng0997-65 (Pubitemid 27377533)
7. Koide R., Kobayashi S., Shimohata T., Ikeuchi T., Maruyama M., Saito M., Yamada M., Takahashi H., Tsuji S., A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease? Human Molecular Genetics 1999 8 11 2047 2053 2-s2.0-0032885515 10.1093/hmg/8.11.2047 (Pubitemid 29458732)
8. Koide R., Ikeuchi T., Onodera O., Tanaka H., Igarashi S., Endo K., Takahashi H., Kondo R., Ishikawa A., Hayashi T., Saito M., Tomoda A., Miike T., Naito H., Ikuta F., Tsuji S., Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nature Genetics 1994 6 1 9 13 2-s2.0-0028216760 10.1038/ng0194-9 (Pubitemid 24191905)
9. Zoghbi H. Y., Orr H. T., Polyglutamine diseases: protein cleavage and aggregation. Current Opinion in Neurobiology 1999 9 5 566 570 2-s2.0-0032824836 10.1016/S0959-4388(99)00013-6 (Pubitemid 29484380)
10. Gatchel J. R., Zoghbi H. Y., Diseases of unstable repeat expansion: mechanisms and common principles. Nature Reviews Genetics 2005 6 10 743 755 2-s2.0-25844487226 10.1038/nrg1691 (Pubitemid 41400832)
11. Solans A., Zambrano A., Rodríguez M., Barrientos A., Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III. Human Molecular Genetics 2006 15 20 3063 3081 2-s2.0-33749557821 10.1093/hmg/ddl248 (Pubitemid 44530710)
12. Bennett E. J., Shaler T. A., Woodman B., Ryu K. Y., Zaitseva T. S., Becker C. H., Bates G. P., Schulman H., Kopito R. R., Global changes to the ubiquitin system in Huntington's disease. Nature 2007 448 7154 704 708 2-s2.0-34547807613 10.1038/nature06022 (Pubitemid 47236860)
13. Chafekar S. M., Duennwald M. L., Impaired heat shock response in cells expressing full-length polyglutamine-expanded Huntingtin. PLoS ONE 2012 7 5 e37929 10.1371/journal.pone.0037929
14. Ou T. T., Wu C. H., Hsu J. D., Chyau C. C., Lee H. J., Wang C. J., Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. Journal of Ethnopharmacology 2011 135 1 162 172 2-s2.0-79955474591 10.1016/j.jep.2011.03.011
15. Liu H. Q., Zhang W. Y., Luo X. T., Ye Y., Zhu X. Z., Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor. British Journal of Pharmacology 2006 148 3 314 325 2-s2.0-33744497031 10.1038/sj.bjp.0706732 (Pubitemid 43801179)
16. Liu D. Z., Zhu J., Jin D. Z., Zhang L. M., Ji X. Q., Ye Y., Tang C. P., Zhu X. Z., Behavioral recovery following sub-chronic paeoniflorin administration in the striatal 6-OHDA lesion rodent model of Parkinson's disease. Journal of Ethnopharmacology 2007 112 2 327 332 2-s2.0-34248597746 10.1016/j.jep.2007.03. 022 (Pubitemid 46756082)
17. (1-42)-mediated neurotoxicity by regulating calcium homeostasis and ameliorating oxidative stress in hippocampus of rats. Journal of the Neurological Sciences 2009 280 1-2 71 78 2-s2.0-63349109688 10.1016/j.jns.2009.01.027
18. Jeon M. H., Kwon H. J., Jeong J. S., Lee Y. M., Hong S. P., Detection of albiflorin and paeoniflorin in Paeoniae Radix by reversed-phase high-performance liquid chromatography with pulsed amperometric detection. Journal of Chromatography A 2009 1216 21 4568 4573 2-s2.0-65249089067 10.1016/j.chroma. 2009.03.058
19. Li S. L., Song J. Z., Choi F. F. K., Qiao C. F., Zhou Y., Han Q. B., Xu H. X., Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2009 49 2 253 266 2-s2.0-59049090924 10.1016/j.jpba.2008.11.007
20. Zhang Y., Koushik S., Dai R., Mivechi N. F., Structural organization and promoter analysis of murine heat shock transcription factor-1 gene. Journal of Biological Chemistry 1998 273 49 32514 32521 2-s2.0-0032484102 10.1074/jbc.273.49.32514 (Pubitemid 28557627)
21. He M., Guo H., Yang X., Zhou L., Zhang X., Cheng L., Zeng H., Hu F. B., Tanguay R. M., Wu T., Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population. PloS One 2010 5 3 e9684 2-s2.0-79952117709
22. Wu Y.-R., Wang C.-K., Chen C.-M., Hsu Y., Lin S.-J., Lin Y.-Y., Fung H.-C., Chang K.-H., Lee-Chen G.-J., Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease. Human Genetics 2004 114 3 236 241 10.1007/s00439-003-1050-1 (Pubitemid 38208300)
23. Lee L.-C., Chen C.-M., Wang H.-C., Hsieh H.-H., Chiu I.-S., Su M.-T., Hsieh-Li H.-M., Wu C.-H., Lee G.-C., Lee-Chen G.-J., Lin J.-Y., Role of the CCAAT-binding protein NFY in SCA17 pathogenesis. PLoS One 2012 7 4 e35302 10.1371/journal.pone.0035302
24. Flis S., Spławiński J., Inhibitory effects of 5-fluorouracil and oxaliplatin on human colorectal cancer cell survival are synergistically enhanced by sulindac sulfide. Anticancer Research 2009 29 1 435 441 2-s2.0-61449117031
25. Haacke A., Broadley S. A., Boteva R., Tzvetkov N., Hartl F. U., Breuer P., Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3. Human Molecular Genetics 2006 15 4 555 568 2-s2.0-32144436256 10.1093/hmg/ddi472 (Pubitemid 43205421)
26. Mielcarek M., Benn C. L., Franklin S. A., SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease. PLoS One 2011 6 11 e27746
27. Iwasaki K., Kato S., Monma Y., Niu K., Ohrui T., Okitsu R., Higuchi S., Ozaki S., Kaneko N., Seki T., Nakayama K., Furukawa K., Fujii M., Arai H., A pilot study of Banxia Houpu Tang, a traditional Chinese medicine, for reducing pneumonia risk in older adults with dementia. Journal of the American Geriatrics Society 2007 55 12 2035 2040 2-s2.0-36849014434 10.1111/j.1532-5415.2007.01448. x (Pubitemid 350230956)
28. Satoh T., Takahashi T., Iwasaki K., Tago H., Seki T., Yaegashi N., Tobita M., Arai H., Traditional Chinese medicine on four patients with Huntington's disease. Movement Disorders 2009 24 3 453 455 2-s2.0-67651094289 10.1002/mds.22447
29. Okabe T., Fujisawa M., Sekiya T., Ichikawa Y., Goto J., Successful treatment of spinocerebellar ataxia 6 with medicinal herbs. Geriatrics & Gerontology International 2007 7 2 195 197
30. He D.-Y., Dai S.-M., Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine. Frontiers in Pharmacology 2011 2, article 10 10.3389/fphar.2011.00010
31. Kim S. H., Lee M. K., Lee K. Y., Sung S. H., Kim J., Kim Y. C., Chemical constituents isolated from Paeonia lactiflora roots and their neuroprotective activity against oxidative stress in vitro. Journal of Enzyme Inhibition and Medicinal Chemistry 2009 24 5 1138 1140 2-s2.0-74549154588 10.1080/ 14756360802667977
32. Yan D., Saito K., Ohmi Y., Fujie N., Ohtsuka K., Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress and Chaperones 2004 9 4 378 389 2-s2.0-12744260179 10.1379/CSC-51R.1
33. Fujimoto M., Takaki E., Hayashi T., Kitaura Y., Tanaka Y., Inouye S., Nakai A., Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models. Journal of Biological Chemistry 2005 280 41 34908 34916 2-s2.0-27144524290 10.1074/jbc.M506288200 (Pubitemid 41504625)
34. Fujikake N., Nagai Y., Popiel H. A., Okamoto Y., Yamaguchi M., Toda T., Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones. Journal of Biological Chemistry 2008 283 38 26188 26197 2-s2.0-54449101793 10.1074/jbc.M710521200
35. Warrick J. M., Chan H. Y. E., Gray-Board G. L., Chai Y., Paulson H. L., Bonini N. M., Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nature Genetics 1999 23 4 425 428 2-s2.0-0032727617 10.1038/70532
36. Cummings C. J., Sun Y., Opal P., Antalffy B., Mestril R., Orr H. T., Dillmann W. H., Zoghbi H. Y., Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Human Molecular Genetics 2001 10 14 1511 1518 2-s2.0-0035394668 (Pubitemid 32684893)
37. Kim S. A., Yoon J. H., Kim D. K., Kim S. G., Ahn S. G., CHIP interacts with heat shock factor 1 during heat stress. FEBS Letters 2005 579 29 6559 6563 2-s2.0-27944489500 10.1016/j.febslet.2005.10.043 (Pubitemid 41682439)
38. Lee L. C., Chen C. M., Chen F. L., Lin P. Y., Hsiao Y. C., Wang P. R., Su M. T., Hsieh-Li H. M., Hwang J. C., Wu C. H., Lee G. C., Singh S., Lin Y., Hsieh S. Y., Lee-Chen G. J., Lin J. Y., Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis. Clinica Chimica Acta 2009 400 1-2 56 62 2-s2.0-57949096490 10.1016/j.cca.2008.10.013
39. Chen C. M., Lee L. C., Soong B. W., Fung H. C., Hsu W. C., Lin P. Y., Huang H. J., Chen F. L., Lin C. Y., Lee-Chen G. J., Wu Y. R., SCA17 repeat expansion: mildly expanded CAG/CAA repeat alleles in neurological disorders and the functional implications. Clinica Chimica Acta 2010 411 5-6 375 380 2-s2.0-74849119374 10.1016/j.cca.2009.12.002