메뉴 건너뛰기




Volumn 525, Issue , 2013, Pages 1-20

Non-motile primary cilia as fluid shear stress mechanosensors

Author keywords

calcium; Fluid flow; nitric oxide; polycystic kidney; polycystins; sensory organelles; shear stress

Indexed keywords

ALPHA TUBULIN; CALCIUM; COLLAGEN; G PROTEIN COUPLED RECEPTOR; NITRATE REDUCTASE; NITRIC OXIDE; POLYCYSTIN 1; POLYCYSTIN 2;

EID: 84875459238     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-397944-5.00001-8     Document Type: Chapter
Times cited : (50)

References (53)
  • 1
  • 2
    • 80052261599 scopus 로고    scopus 로고
    • Calcium-mediated mechanisms of cystic expansion
    • S. Abdul-Majeed, and S.M. Nauli Calcium-mediated mechanisms of cystic expansion Biochimica et Biophysica Acta 1812 10 2011 1281 1290
    • (2011) Biochimica et Biophysica Acta , vol.1812 , Issue.10 , pp. 1281-1290
    • Abdul-Majeed, S.1    Nauli, S.M.2
  • 3
    • 80051469652 scopus 로고    scopus 로고
    • Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles
    • S. Abdul-Majeed, and S.M. Nauli Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles Hypertension 58 2 2011 325 331
    • (2011) Hypertension , vol.58 , Issue.2 , pp. 325-331
    • Abdul-Majeed, S.1    Nauli, S.M.2
  • 5
    • 70350023377 scopus 로고    scopus 로고
    • Primary cilia: Highly sophisticated biological sensors
    • W.A. AbouAlaiwi, S.T. Lo, and S.M. Nauli Primary cilia: Highly sophisticated biological sensors Sensors (Basel) 9 9 2009 7003 7020
    • (2009) Sensors (Basel) , vol.9 , Issue.9 , pp. 7003-7020
    • Aboualaiwi, W.A.1    Lo, S.T.2    Nauli, S.M.3
  • 6
    • 78650573315 scopus 로고    scopus 로고
    • Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation
    • W.A. AbouAlaiwi, S. Ratnam, R.L. Booth, J.V. Shah, and S.M. Nauli Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation Human Molecular Genetics 20 2 2011 354 367
    • (2011) Human Molecular Genetics , vol.20 , Issue.2 , pp. 354-367
    • Aboualaiwi, W.A.1    Ratnam, S.2    Booth, R.L.3    Shah, J.V.4    Nauli, S.M.5
  • 7
    • 65249117068 scopus 로고    scopus 로고
    • Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades
    • W.A. AbouAlaiwi, M. Takahashi, B.R. Mell, T.J. Jones, S. Ratnam, and R.J. Kolb Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades Circulation Research 104 7 2009 860 869
    • (2009) Circulation Research , vol.104 , Issue.7 , pp. 860-869
    • Aboualaiwi, W.A.1    Takahashi, M.2    Mell, B.R.3    Jones, T.J.4    Ratnam, S.5    Kolb, R.J.6
  • 8
    • 84856360903 scopus 로고    scopus 로고
    • Stages of ciliogenesis and regulation of ciliary length
    • P. Avasthi, and W.F. Marshall Stages of ciliogenesis and regulation of ciliary length Differentiation 83 2 2012 S30 S42
    • (2012) Differentiation , vol.83 , Issue.2
    • Avasthi, P.1    Marshall, W.F.2
  • 9
    • 44449106038 scopus 로고    scopus 로고
    • Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors
    • N.F. Berbari, A.D. Johnson, J.S. Lewis, C.C. Askwith, and K. Mykytyn Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors Molecular Biology of the Cell 19 4 2008 1540 1547
    • (2008) Molecular Biology of the Cell , vol.19 , Issue.4 , pp. 1540-1547
    • Berbari, N.F.1    Johnson, A.D.2    Lewis, J.S.3    Askwith, C.C.4    Mykytyn, K.5
  • 11
    • 4243144134 scopus 로고    scopus 로고
    • Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization
    • D.A. Cano, N.S. Murcia, G.J. Pazour, and M. Hebrok Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization Development 131 14 2004 3457 3467
    • (2004) Development , vol.131 , Issue.14 , pp. 3457-3467
    • Cano, D.A.1    Murcia, N.S.2    Pazour, G.J.3    Hebrok, M.4
  • 12
    • 33845661591 scopus 로고    scopus 로고
    • Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis
    • D.A. Cano, S. Sekine, and M. Hebrok Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis Gastroenterology 131 6 2006 1856 1869
    • (2006) Gastroenterology , vol.131 , Issue.6 , pp. 1856-1869
    • Cano, D.A.1    Sekine, S.2    Hebrok, M.3
  • 14
    • 79959653860 scopus 로고    scopus 로고
    • A role for the primary cilium in Notch signaling and epidermal differentiation during skin development
    • E.J. Ezratty, N. Stokes, S. Chai, A.S. Shah, S.E. Williams, and E. Fuchs A role for the primary cilium in Notch signaling and epidermal differentiation during skin development Cell 145 7 2011 1129 1141
    • (2011) Cell , vol.145 , Issue.7 , pp. 1129-1141
    • Ezratty, E.J.1    Stokes, N.2    Chai, S.3    Shah, A.S.4    Williams, S.E.5    Fuchs, E.6
  • 16
    • 79951796053 scopus 로고    scopus 로고
    • Regulation of renal NaCl transport by nitric oxide, endothelin, and ATP: Clinical implications
    • J.L. Garvin, M. Herrera, and P.A. Ortiz Regulation of renal NaCl transport by nitric oxide, endothelin, and ATP: Clinical implications Annual Review of Physiology 73 2011 359 376
    • (2011) Annual Review of Physiology , vol.73 , pp. 359-376
    • Garvin, J.L.1    Herrera, M.2    Ortiz, P.A.3
  • 18
    • 67349153122 scopus 로고    scopus 로고
    • The polycystic kidney disease 1 (Pkd1) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice
    • B. Hou, E. Kolpakova-Hart, N. Fukai, K. Wu, and B.R. Olsen The polycystic kidney disease 1 (Pkd1) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice Bone 44 6 2009 1121 1133
    • (2009) Bone , vol.44 , Issue.6 , pp. 1121-1133
    • Hou, B.1    Kolpakova-Hart, E.2    Fukai, N.3    Wu, K.4    Olsen, B.R.5
  • 19
    • 79956308325 scopus 로고    scopus 로고
    • Mechanisms and functions of Hedgehog signalling across the metazoa
    • Ingham P.W., Nakano Y., and Seger C. Mechanisms and functions of Hedgehog signalling across the metazoa Nat Rev Genet 12 6 2011 393 406
    • (2011) Nat Rev Genet , vol.12 , Issue.6 , pp. 393-406
    • Ingham, P.W.1    Nakano, Y.2    Seger, C.3
  • 20
    • 77955799439 scopus 로고    scopus 로고
    • Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells
    • R.Y. Kwon, S. Temiyasathit, P. Tummala, C.C. Quah, and C.R. Jacobs Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells The FASEB Journal 24 8 2010 2859 2868
    • (2010) The FASEB Journal , vol.24 , Issue.8 , pp. 2859-2868
    • Kwon, R.Y.1    Temiyasathit, S.2    Tummala, P.3    Quah, C.C.4    Jacobs, C.R.5
  • 22
    • 29744470060 scopus 로고    scopus 로고
    • Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease
    • S.H. Low, S. Vasanth, C.H. Larson, S. Mukherjee, N. Sharma, and M.T. Kinter Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease Developmental Cell 10 1 2006 57 69
    • (2006) Developmental Cell , vol.10 , Issue.1 , pp. 57-69
    • Low, S.H.1    Vasanth, S.2    Larson, C.H.3    Mukherjee, S.4    Sharma, N.5    Kinter, M.T.6
  • 23
    • 0035504102 scopus 로고    scopus 로고
    • Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
    • W. Lu, X. Shen, A. Pavlova, M. Lakkis, C.J. Ward, and L. Pritchard Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects Human Molecular Genetics 10 21 2001 2385 2396
    • (2001) Human Molecular Genetics , vol.10 , Issue.21 , pp. 2385-2396
    • Lu, W.1    Shen, X.2    Pavlova, A.3    Lakkis, M.4    Ward, C.J.5    Pritchard, L.6
  • 26
    • 33745710680 scopus 로고    scopus 로고
    • Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2 + and cAMP signaling
    • A.I. Masyuk, T.V. Masyuk, P.L. Splinter, B.Q. Huang, A.J. Stroope, and N.F. LaRusso Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2 + and cAMP signaling Gastroenterology 131 3 2006 911 920
    • (2006) Gastroenterology , vol.131 , Issue.3 , pp. 911-920
    • Masyuk, A.I.1    Masyuk, T.V.2    Splinter, P.L.3    Huang, B.Q.4    Stroope, A.J.5    Larusso, N.F.6
  • 27
    • 0038784537 scopus 로고    scopus 로고
    • Two populations of node monocilia initiate left-right asymmetry in the mouse
    • J. McGrath, S. Somlo, S. Makova, X. Tian, and M. Brueckner Two populations of node monocilia initiate left-right asymmetry in the mouse Cell 114 1 2003 61 73
    • (2003) Cell , vol.114 , Issue.1 , pp. 61-73
    • McGrath, J.1    Somlo, S.2    Makova, S.3    Tian, X.4    Brueckner, M.5
  • 28
    • 33748089680 scopus 로고    scopus 로고
    • Localization of extracellular matrix receptors on the chondrocyte primary cilium
    • McGlashan S.R., Jensen C.G., and Poole C.A. Localization of extracellular matrix receptors on the chondrocyte primary cilium J Histochem Cytochem 54 9 2006 1005 1014
    • (2006) J Histochem Cytochem , vol.54 , Issue.9 , pp. 1005-1014
    • McGlashan, S.R.1    Jensen, C.G.2    Poole, C.A.3
  • 29
    • 0037317302 scopus 로고    scopus 로고
    • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
    • S.M. Nauli, F.J. Alenghat, Y. Luo, E. Williams, P. Vassilev, and X. Li Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells Nature Genetics 33 2 2003 129 137
    • (2003) Nature Genetics , vol.33 , Issue.2 , pp. 129-137
    • Nauli, S.M.1    Alenghat, F.J.2    Luo, Y.3    Williams, E.4    Vassilev, P.5    Li, X.6
  • 30
    • 80051473455 scopus 로고    scopus 로고
    • Primary cilia are mechanosensory organelles in vestibular tissues
    • Andre Kamkin, Irina Kiseleva, Springer New York (chapter 14) ISBN: 978-990-481-9880-9881
    • S.M. Nauli, H.S. Haymour, W.A. AbouAlaiwi, S.T. Lo, and A.M. Nauli Primary cilia are mechanosensory organelles in vestibular tissues Andre Kamkin, Irina Kiseleva, Mechanosensitivity and mechanotransduction 2011 Springer New York (chapter 14) ISBN: 978-990-481-9880-9881
    • (2011) Mechanosensitivity and Mechanotransduction
    • Nauli, S.M.1    Haymour, H.S.2    Aboualaiwi, W.A.3    Lo, S.T.4    Nauli, A.M.5
  • 31
    • 39849099174 scopus 로고    scopus 로고
    • Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1
    • S.M. Nauli, Y. Kawanabe, J.J. Kaminski, W.J. Pearce, D.E. Ingber, and J. Zhou Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1 Circulation 117 9 2008 1161 1171
    • (2008) Circulation , vol.117 , Issue.9 , pp. 1161-1171
    • Nauli, S.M.1    Kawanabe, Y.2    Kaminski, J.J.3    Pearce, W.J.4    Ingber, D.E.5    Zhou, J.6
  • 35
    • 4344672618 scopus 로고    scopus 로고
    • Polycystins and mechanosensation in renal and nodal cilia
    • S.M. Nauli, and J. Zhou Polycystins and mechanosensation in renal and nodal cilia Bioessays 26 8 2004 844 856
    • (2004) Bioessays , vol.26 , Issue.8 , pp. 844-856
    • Nauli, S.M.1    Zhou, J.2
  • 37
    • 0035498717 scopus 로고    scopus 로고
    • Bending the MDCK cell primary cilium increases intracellular calcium
    • H.A. Praetorius, and K.R. Spring Bending the MDCK cell primary cilium increases intracellular calcium The Journal of Membrane Biology 184 1 2001 71 79
    • (2001) The Journal of Membrane Biology , vol.184 , Issue.1 , pp. 71-79
    • Praetorius, H.A.1    Spring, K.R.2
  • 38
    • 0037557518 scopus 로고    scopus 로고
    • Removal of the MDCK cell primary cilium abolishes flow sensing
    • H.A. Praetorius, and K.R. Spring Removal of the MDCK cell primary cilium abolishes flow sensing The Journal of Membrane Biology 191 1 2003 69 76
    • (2003) The Journal of Membrane Biology , vol.191 , Issue.1 , pp. 69-76
    • Praetorius, H.A.1    Spring, K.R.2
  • 39
    • 6344277202 scopus 로고    scopus 로고
    • Beta1-integrins in the primary cilium of MDCK cells potentiate fibronectin-induced Ca2+ signaling
    • H.A. Praetorius, J. Praetorius, S. Nielsen, J. Frokiaer, and K.R. Spring Beta1-integrins in the primary cilium of MDCK cells potentiate fibronectin-induced Ca2+ signaling Am J Physiol Renal Physiol 287 5 2004 F969 978
    • (2004) Am J Physiol Renal Physiol , vol.287 , Issue.5 , pp. 969-978
    • Praetorius, H.A.1    Praetorius, J.2    Nielsen, S.3    Frokiaer, J.4    Spring, K.R.5
  • 40
    • 84863084212 scopus 로고    scopus 로고
    • Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia
    • N. Qiu, Z. Xiao, L. Cao, M.M. Buechel, V. David, and E. Roan Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia Journal of Cell Science 125 8 2012 1945 1957
    • (2012) Journal of Cell Science , vol.125 , Issue.8 , pp. 1945-1957
    • Qiu, N.1    Xiao, Z.2    Cao, L.3    Buechel, M.M.4    David, V.5    Roan, E.6
  • 41
    • 80055054075 scopus 로고    scopus 로고
    • Chronic fluid flow is an environmental modifier of renal epithelial function
    • A. Resnick Chronic fluid flow is an environmental modifier of renal epithelial function PLoS One 6 10 2011 e27058
    • (2011) PLoS One , vol.6 , Issue.10 , pp. 27058
    • Resnick, A.1
  • 42
    • 76349121314 scopus 로고    scopus 로고
    • Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts
    • L. Schneider, M. Cammer, J. Lehman, S.K. Nielsen, C.F. Guerra, and I.R. Veland Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts Cellular Physiology and Biochemistry 25 2-3 2010 279 292
    • (2010) Cellular Physiology and Biochemistry , vol.25 , Issue.23 , pp. 279-292
    • Schneider, L.1    Cammer, M.2    Lehman, J.3    Nielsen, S.K.4    Guerra, C.F.5    Veland, I.R.6
  • 43
    • 65249108743 scopus 로고    scopus 로고
    • The Na +/H + exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium
    • L. Schneider, C.M. Stock, P. Dieterich, B.H. Jensen, L.B. Pedersen, and P. Satir The Na +/H + exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium The Journal of Cell Biology 185 1 2009 163 176
    • (2009) The Journal of Cell Biology , vol.185 , Issue.1 , pp. 163-176
    • Schneider, L.1    Stock, C.M.2    Dieterich, P.3    Jensen, B.H.4    Pedersen, L.B.5    Satir, P.6
  • 44
    • 84857489355 scopus 로고    scopus 로고
    • TGF-beta signaling in endothelial-to-mesenchymal transition: The role of shear stress and primary cilia
    • P. Ten Dijke, A.D. Egorova, M.J. Goumans, R.E. Poelmann, and B.P. Hierck TGF-beta signaling in endothelial-to-mesenchymal transition: The role of shear stress and primary cilia Science Signaling 5 212 2012 pt2
    • (2012) Science Signaling , vol.5 , Issue.212 , pp. 2
    • Ten Dijke, P.1    Egorova, A.D.2    Goumans, M.J.3    Poelmann, R.E.4    Hierck, B.P.5
  • 46
    • 0024550450 scopus 로고
    • The oxidation of the calcium probe quin2 and its analogs by prostaglandin H synthase
    • J. Van der Zee, R.P. Mason, and T.E. Eling The oxidation of the calcium probe quin2 and its analogs by prostaglandin H synthase Archives of Biochemistry and Biophysics 271 1 1989 64 71
    • (1989) Archives of Biochemistry and Biophysics , vol.271 , Issue.1 , pp. 64-71
    • Van Der Zee, J.1    Mason, R.P.2    Eling, T.E.3
  • 47
    • 84055184240 scopus 로고    scopus 로고
    • Endothelial function
    • J.A. Vita Endothelial function Circulation 124 25 2011 e906 e912
    • (2011) Circulation , vol.124 , Issue.25
    • Vita, J.A.1
  • 48
    • 79955765994 scopus 로고    scopus 로고
    • The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: Role of cAMP signaling in primary cilia
    • Z. Wang, T. Phan, and D.R. Storm The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: Role of cAMP signaling in primary cilia The Journal of Neuroscience 31 15 2011 5557 5561
    • (2011) The Journal of Neuroscience , vol.31 , Issue.15 , pp. 5557-5561
    • Wang, Z.1    Phan, T.2    Storm, D.R.3
  • 49
    • 45549101592 scopus 로고    scopus 로고
    • Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II
    • Z. Xiao, S. Zhang, B.S. Magenheimer, J. Luo, and L.D. Quarles Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II The Journal of Biological Chemistry 283 18 2008 12624 12634
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.18 , pp. 12624-12634
    • Xiao, Z.1    Zhang, S.2    Magenheimer, B.S.3    Luo, J.4    Quarles, L.D.5
  • 50
    • 33750067366 scopus 로고    scopus 로고
    • Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression
    • Z. Xiao, S. Zhang, J. Mahlios, G. Zhou, B.S. Magenheimer, and D. Guo Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression The Journal of Biological Chemistry 281 41 2006 30884 30895
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.41 , pp. 30884-30895
    • Xiao, Z.1    Zhang, S.2    Mahlios, J.3    Zhou, G.4    Magenheimer, B.S.5    Guo, D.6
  • 51
    • 33847792873 scopus 로고    scopus 로고
    • Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2 + signaling
    • C. Xu, S. Rossetti, L. Jiang, P.C. Harris, U. Brown-Glaberman, and A. Wandinger-Ness Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2 + signaling American Journal of Physiology. Renal Physiology 292 3 2007 F930 F945
    • (2007) American Journal of Physiology. Renal Physiology , vol.292 , Issue.3
    • Xu, C.1    Rossetti, S.2    Jiang, L.3    Harris, P.C.4    Brown-Glaberman, U.5    Wandinger-Ness, A.6
  • 52
    • 66449122451 scopus 로고    scopus 로고
    • Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2 + signaling in human ADPKD cyst epithelial cells
    • C. Xu, B.E. Shmukler, K. Nishimura, E. Kaczmarek, S. Rossetti, and P.C. Harris Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2 + signaling in human ADPKD cyst epithelial cells American Journal of Physiology. Renal Physiology 296 6 2009 F1464 F1476
    • (2009) American Journal of Physiology. Renal Physiology , vol.296 , Issue.6
    • Xu, C.1    Shmukler, B.E.2    Nishimura, K.3    Kaczmarek, E.4    Rossetti, S.5    Harris, P.C.6
  • 53
    • 67649844614 scopus 로고    scopus 로고
    • Polycystins and primary cilia: Primers for cell cycle progression
    • J. Zhou Polycystins and primary cilia: Primers for cell cycle progression Annual Review of Physiology 71 2009 83 113
    • (2009) Annual Review of Physiology , vol.71 , pp. 83-113
    • Zhou, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.