Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation

Human Molecular Genetics

Volumn 20, Issue 2, 2011, Pages 354-367

  AbouAlaiwi, Wissam A ^a   Ratnam, Shobha ^b   Booth, Robert L ^b   Shah, Jagesh V ^c   Nauli, Surya M ^a,b  

^a Department of Medicinal Chemistry   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCYSTIN; SURVIVIN;

AGED; AGING; ANAPHASE; ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CARDIOVASCULAR DISEASE; CELL CYCLE G0 PHASE; CELL CYCLE REGULATION; CELL DIVISION; CELL FUNCTION; CELL MUTANT; CELL PROLIFERATION; CELL STRUCTURE; CENTROSOME; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CILIARY MOTILITY; CONTROLLED STUDY; CYTOKINESIS; DISEASE COURSE; DOWN REGULATION; EMBRYO; ENDOTHELIUM CELL; EUKARYOTIC FLAGELLUM; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; KIDNEY POLYCYSTIC DISEASE; METAPHASE; MITOSIS SPINDLE; NONHUMAN; PHENOTYPE; POLYPLOIDY; PRIORITY JOURNAL; PROPHASE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TELOPHASE;

ANIMALS; CELL PROLIFERATION; CENTROSOME; CHROMOSOME SEGREGATION; CILIA; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMIC INSTABILITY; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; KARYOTYPING; MICE; MITOTIC SPINDLE APPARATUS; PHOSPHATIDYLINOSITOL 3-KINASES; POLYCYSTIC KIDNEY DISEASES; POLYPLOIDY; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; MUS;

EID: 78650573315     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq470     Document Type: Article

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