Protein phosphatase 1 coordinates CFTR-dependent airway epithelial HCO 3- secretion by reciprocal regulation of apical and basolateral membrane Cl--HCO3-exchangers

British Journal of Pharmacology

Volumn 168, Issue 8, 2013, Pages 1946-1960

  Garnett, James P ^a,d   Hickman, Emma ^b   Tunkamnerdthai, Orathai ^a   Cuthbert, Alan W ^c   Gray, Michael A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

airway disease; anion exchange; bicarbonate secretion; CFTR; cystic fibrosis; pendrin; protein phosphatase 1; submucosal gland serous cells

Indexed keywords

BICARBONATE CHLORIDE EXCHANGER; CARRIER PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FOSTRIECIN; GLYH 101; OKADAIC ACID; PENDRIN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; BICARBONATE; BICARBONATE CHLORIDE ANTIPORTER; CFTR PROTEIN, HUMAN; ENZYME INHIBITOR; GLYCINE; HYDRAZINE DERIVATIVE; N-(2-NAPHTHALENYL)-((3,5-DIBROMO-2,4-DIHYDROXYPHENYL)METHYLENE)GLYCINE HYDRAZIDE; POLYENE; PYRONE DERIVATIVE; SLC26A4 PROTEIN, HUMAN;

ALKALINIZATION; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL PH; CELLULAR DISTRIBUTION; CELLULAR SECRETION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; AGONISTS; ANALOGS AND DERIVATIVES; CELL MEMBRANE; CYTOLOGY; METABOLISM; RESPIRATORY SYSTEM; TUMOR CELL LINE;

BICARBONATES; CELL LINE, TUMOR; CELL MEMBRANE; CHLORIDE-BICARBONATE ANTIPORTERS; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME INHIBITORS; GLYCINE; HUMANS; HYDRAZINES; MEMBRANE TRANSPORT PROTEINS; OKADAIC ACID; POLYENES; PROTEIN PHOSPHATASE 1; PYRONES; RESPIRATORY SYSTEM;

EID: 84875454218     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12085     Document Type: Article

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