The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A

Journal of Biological Chemistry

Volumn 280, Issue 50, 2005, Pages 41512-41520

  Thelin, William R ^a   Kesimer, Mehmet ^b   Tarran, Robert ^b   Kreda, Silvia M ^b   Grubb, Barbara R ^b   Sheehan, John K ^b   Stutts, M Jackson ^b   Milgram, Sharon L ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; ENZYME KINETICS; MOLECULAR DYNAMICS; PROTEINS; SURFACE PHENOMENA;

AIRWAY SURFACE LIQUID; CATALYTIC SUBUNIT; CHANNEL REGULATION; EPITHELIAL CELLS;

TUMORS;

CHLORIDE CHANNEL; CYCLIC AMP; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; BRONCHUS MUCOSA; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME SPECIFICITY; ENZYME SUBUNIT; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM;

AMINO ACID SEQUENCE; BIOTINYLATION; BRONCHI; CATALYTIC DOMAIN; CELL LINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIMERIZATION; EPITHELIUM; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 29244437861     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M507308200     Document Type: Article

References (56)

1. Cheng, S. H., Rich, D. P., Marshall, J., Gregory, R. J., Welsh, M. J., and Smith, A. E. (1991) Cell 66, 1027-1036
2. Seibert, F. S., Tabcharani, J. A., Chang, X. B., Dulhanty, A. M., Mathews, C., Hanrahan, J. W., and Riordan, J. R. (1995) J. Biol. Chem. 270, 2158-2162
3. Chang, X. B., Tabcharani, J. A., Hou, Y. X., Jensen, T. J., Kartner, N., Alon, N., Hanrahan, J. W., and Riordan, J. R. (1993) J. Biol. Chem. 268, 11304-11311
4. Gadsby, D. C., and Nairn, A. C. (1999) Physiol. Rev. 79, Suppl. 1, 77-107
5. Ameen, N. A., Marino, C., and Salas, P. J. (2003) Am. J. Physiol. 284, C429-C438
6. Huang, P., Lazarowski, E. R., Tarran, R., Milgram, S. L., Boucher, R. C., and Stutts, M. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 14120-14125
7. Sun, F., Hug, M. J., Lewarchik, C. M., Yun, C. H., Bradbury, N. A., and Frizzell, R. A. (2000) J. Biol. Chem. 275, 29539-29546
8. Sun, F., Hug, M. J., Bradbury, N. A., and Frizzell, R. A. (2000) J. Biol. Chem. 275, 14360-14366
9. Huang, P., Trotter, K., Boucher, R. C., Milgram, S. L., and Stutts, M. J. (2000) Am. J. Physiol. 278, C417-C422
10. Barnes, A. P., Livera, G., Huang, P., Sun, C., O'Neal, W. K., Conti, M., Stutts, M. J., and Milgram, S. L. (2005) J. Biol. Chem. 280, 7997-8003
11. Liedtke, C. M., Yun, C. H., Kyle, N., and Wang, D. (2002) J. Biol. Chem. 277, 22925-22933
12. Hallows, K. R., Raghuram, V., Kemp, B. E., Witters, L. A., and Foskett, J. K. (2000) J. Clin. Invest. 105, 1711-1721
13. Luo, J., Pato, M. D., Riordan, J. R., and Hanrahan, J. W. (1998) Am. J. Physiol. 274, C1397-C1410
14. Hwang, T. C., Horie, M., and Gadsby, D. C. (1993) J. Gen. Physiol. 101, 629-650
15. Travis, S. M., Berger, H. A., and Welsh, M. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 11055-11060
16. Reddy, M. M., and Quinton, P. M. (1996) Am. J. Physiol. 270, C474-C480
17. Fischer, H., Illek, B., and Machen, T. E. (1998) Pflugers Arch. 436, 175-181
18. Berger, H. A., Travis, S. M., and Welsh, M. J. (1993) J. Biol. Chem. 268, 2037-2047
19. Yang, I. C., Cheng, T. H., Wang, F., Price, E. M., and Hwang, T. C. (1997) Am. J. Physiol. 272, C142-C155
20. Zhu, T., Dahan, D., Evagelidis, A., Zheng, S., Luo, J., and Hanrahan, J. W. (1999) J. Biol. Chem. 274, 29102-29107
21. Mohler, P. J., Kreda, S. M., Boucher, R. C., Sudol, M., Stutts, M. J., and Milgram, S. L. (1999) J. Cell Biol. 147, 879-890
22. Kreda, S. M., Mall, M., Mengos, A., Rochelle, L., Yankaskas, J., Riordan, J. R., and Boucher, R. C. (2005) Mol. Biol. Cell 16, 2154-2167
23. Scott, R. O., Thelin, W. R., and Milgram, S. L. (2002) J. Biol. Chem. 277, 22934-22941
24. Smith, F. D., Oxford, G. S., and Milgram, S. L. (1999) J. Biol. Chem. 274, 19894-19900
25. Grubb, B. R. (1995) Am. J. Physiol. 268, G505-G513
26. Grubb, B. R. (2002) Methods Mol. Med. 70, 525-535
27. Tarran, R., Grubb, B. R., Parsons, D., Picher, M., Hirsh, A. J., Davis, C. W., and Boucher, R. C. (2001) Mol. Cell 8, 149-158
28. Cheng, J., Moyer, B. D., Milewski, M., Loffing, J., Ikeda, M., Mickle, J. E., Cutting, G. R., Li, M., Stanton, B. A., and Guggino, W. B. (2002) J. Biol. Chem. 277, 3520-3529
29. Short, D. B., Trotter, K. W., Reczek, D., Kreda, S. M., Bretscher, A., Boucher, R. C., Stutts, M. J., and Milgram, S. L. (1998) J. Biol. Chem. 273, 19797-19801
30. Wang, S., Yue, H., Derin, R. B., Guggino, W. B., and Li, M. (2000) Cell 103, 169-179
31. Weixel, K. M., and Bradbury, N. A. (2000) J. Mol. Chem. 275, 3655-3660
32. Ostedgaard, L. S., Randak, C., Rokhlina, T., Karp, P., Vermeer, D., Ashbourne Excoffon, K. J., and Welsh, M. J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 1937-1942
33. Vastiau, A., Cao, L., Jaspers, M., Owsianik, G., Janssens, V., Cuppens, H., Goris, J., Nilius, B., and Cassiman, J. J. (2005) FEBS Lett. 579, 3392-3396
34. Janssens, V., and Goris, J. (2001) Biochem. J. 353, 417-439
35. McCright, B., Rivers, A. M., Audlin, S., and Virshup, D. M. (1996) J. Biol. Chem. 271, 22081-22089
36. Tarran, R., Button, B., Picher, M., Paradiso, A. M., Ribeiro, C. M., Lazarowski, E. R., Zhang, L., Collins, P. L., Pickles, R. J., Fredburg, J. J., and Boucher, R. C. (2005) J. Biol. Chem. 280, 35751-35759
37. Tabcharani, J. A., Chang, X. B., Riordan, J. R., and Hanrahan, J. W. (1991) Nature 352, 628-631
38. Berger, H. A., Anderson, M. P., Gregory, R. J., Thompson, S., Howard, P. W., Maurer, R. A., Mulligan, R., Smith, A. E., and Welsh, M. J. (1991) J. Clin. Invest. 88, 1422-1431
39. Brewis, N. D., Street, A. J., Prescott, A. R., and Cohen, P. T. (1993) EMBO J. 12, 987-996
40. Becker, W., Kentrup, H., Klumpp, S., Schultz, J. E., and Joost, H. G. (1994) J. Biol. Chem. 269, 22586-22592
41. Li, M., Quo, H., and Damuni, Z. (1995) Biochemistry 34, 1988-1996
42. Li, M., Makkinje, A., and Damuni, Z. (1996) J. Biol. Chem. 271, 11059-11062
43. Clarke, L. L., Grubb, B. R., Gabriel, S. E., Smithies, O., Koller, B. H., and Boucher, R. C. (1992) Science 257, 1125-1128
44. Guggino, W. B. (2001) Nat. Med. 7, 888-889
45. Verkman, A. S. (2001) Am. J. Physiol. 281, L306-L308
46. Knowles, M. R., and Boucher, R. C. (2002) J. Clin. Invest. 109, 571-577
47. Wine, J. J. (1999) J. Clin. Invest. 103, 309-312
48. Matsui, H., Randell, S. H., Peretti, S. W., Davis, C. W., and Boucher, R. C. (1998) J. Clin. Invest. 102, 1125-1131
49. Tarran, R., Loewen, M. E., Paradiso, A. M., Olsen, J. C., Gray, M. A., Argent, B. E., Boucher, R. C., and Gabriel, S. E. (2002) J. Gen. Physiol. 120, 407-418
50. Ma, T., Thiagarajah, J. R., Yang, H., Sonawane, N. D., Folli, C., Galietta, L. J., and Verkman, A. S. (2002) J. Clin. Invest. 110, 1651-1658
51. Tehrani, M. A., Mumby, M. C., and Kamibayashi, C. (1996) J. Biol. Chem. 271, 5164-5170
52. Ruediger, R., Hentz, M., Fait, J., Mumby, M., and Walter, G. (1994) J. Virol. 68, 123-129
53. Ruediger, R., Roeckel, D., Fait, J., Bergqvist, A., Magnusson, G., and Walter, G. (1992) Mol. Cell. Biol. 12, 4872-4882
54. Dozier, C., Bonyadi, M., Baricault, L., Tonasso, L., and Darbon, J. M. (2004) Biol. Cell 96, 509-517
55. Matsui, H., Grubb, B. R., Tarran, R., Randell, S. H., Gatzy, J. T., Davis, C. W., and Boucher, R. C. (1998) Cell 95, 1005-1015
56. Gimeno-Alcaniz, J. V., and Sanz, P. (2003) J. Mol. Biol. 333, 201-209