-
1
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, et al. (2003) Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
-
2
-
-
0025251790
-
Inhibition of Insulin-Secretion from Rat Islets of Langerhans by Interleukin-6 - an Effect Distinct from That of Interleukin-1
-
Southern C, Schulster D, Green IC, (1990) Inhibition of Insulin-Secretion from Rat Islets of Langerhans by Interleukin-6- an Effect Distinct from That of Interleukin-1. Biochem J 272: 243-245.
-
(1990)
Biochem J
, vol.272
, pp. 243-245
-
-
Southern, C.1
Schulster, D.2
Green, I.C.3
-
3
-
-
0036894360
-
Interleukin-6 induces cellular insulin resistance in hepatocytes
-
Senn JJ, Klover PJ, Nowak IA, Mooney RA, (2002) Interleukin-6 induces cellular insulin resistance in hepatocytes. Diabetes 51: 3391-3399.
-
(2002)
Diabetes
, vol.51
, pp. 3391-3399
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Mooney, R.A.4
-
4
-
-
0242580711
-
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
-
Rotter V, Nagaev I, Smith U, (2003) Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278: 45777-45784.
-
(2003)
J Biol Chem
, vol.278
, pp. 45777-45784
-
-
Rotter, V.1
Nagaev, I.2
Smith, U.3
-
5
-
-
0037853260
-
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
-
Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, et al. (2003) Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J Biol Chem 278: 13740-13746.
-
(2003)
J Biol Chem
, vol.278
, pp. 13740-13746
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Zimmers, T.A.4
Koniaris, L.G.5
-
6
-
-
0242268894
-
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice
-
Klover PJ, Zimmers TA, Koniaris LG, Mooney RA, (2003) Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 52: 2784-2789.
-
(2003)
Diabetes
, vol.52
, pp. 2784-2789
-
-
Klover, P.J.1
Zimmers, T.A.2
Koniaris, L.G.3
Mooney, R.A.4
-
7
-
-
23044468612
-
Interleukin-6 depletion selectively improves hepatic insulin action in obesity
-
Klover PJ, Clementi AH, Mooney RA, (2005) Interleukin-6 depletion selectively improves hepatic insulin action in obesity. Endocrinology 146: 3417-3427.
-
(2005)
Endocrinology
, vol.146
, pp. 3417-3427
-
-
Klover, P.J.1
Clementi, A.H.2
Mooney, R.A.3
-
8
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, et al. (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116: 1494-1505.
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
Kotani, K.4
Hiasa, K.5
-
9
-
-
0037317763
-
Innate immune sensing and its roots: the story of endotoxin
-
Beutler B, Rietschel ET, (2003) Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol 3: 169-176.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 169-176
-
-
Beutler, B.1
Rietschel, E.T.2
-
10
-
-
67349182481
-
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
-
Park BS, Song DH, Kim HM, Choi BS, Lee H, et al. (2009) The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 458: 1191-1195.
-
(2009)
Nature
, vol.458
, pp. 1191-1195
-
-
Park, B.S.1
Song, D.H.2
Kim, H.M.3
Choi, B.S.4
Lee, H.5
-
11
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, et al. (2007) Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56: 1761-1772.
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
Amar, J.2
Iglesias, M.A.3
Poggi, M.4
Knauf, C.5
-
12
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, et al. (2006) TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116: 3015-3025.
-
(2006)
J Clin Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
-
13
-
-
84859449180
-
Saturated fatty acid and TLR signaling link beta cell dysfunction and islet inflammation
-
Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, et al. (2012) Saturated fatty acid and TLR signaling link beta cell dysfunction and islet inflammation. Cell Metab 15: 518-533.
-
(2012)
Cell Metab
, vol.15
, pp. 518-533
-
-
Eguchi, K.1
Manabe, I.2
Oishi-Tanaka, Y.3
Ohsugi, M.4
Kono, N.5
-
14
-
-
0031586174
-
Identification and characterization of an IkappaB kinase
-
Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, et al. (1997) Identification and characterization of an IkappaB kinase. Cell 90: 373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
-
15
-
-
0032217264
-
Structure of an IkappaBalpha/NF-kappaB complex
-
Jacobs MD, Harrison SC, (1998) Structure of an IkappaBalpha/NF-kappaB complex. Cell 95: 749-758.
-
(1998)
Cell
, vol.95
, pp. 749-758
-
-
Jacobs, M.D.1
Harrison, S.C.2
-
16
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl K, (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 12: 599-606.
-
(1998)
Genes Dev
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
17
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD, (2000) The language of covalent histone modifications. Nature 403: 41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
18
-
-
28044471827
-
Acetylation and deacetylation of non-histone proteins
-
Glozak MA, Sengupta N, Zhang X, Seto E, (2005) Acetylation and deacetylation of non-histone proteins. Gene 363: 15-23.
-
(2005)
Gene
, vol.363
, pp. 15-23
-
-
Glozak, M.A.1
Sengupta, N.2
Zhang, X.3
Seto, E.4
-
19
-
-
37849019672
-
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
-
Khan N, Jeffers M, Kumar S, Hackett C, Boldog F, et al. (2008) Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors. Biochem J 409: 581-589.
-
(2008)
Biochem J
, vol.409
, pp. 581-589
-
-
Khan, N.1
Jeffers, M.2
Kumar, S.3
Hackett, C.4
Boldog, F.5
-
20
-
-
13544265432
-
Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?
-
Blanchard F, Chipoy C, (2005) Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases? Drug Discov Today 10: 197-204.
-
(2005)
Drug Discov Today
, vol.10
, pp. 197-204
-
-
Blanchard, F.1
Chipoy, C.2
-
21
-
-
0033821409
-
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
-
Ito K, Barnes PJ, Adcock IM, (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol Cell Biol 20: 6891-6903.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
22
-
-
0034802887
-
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
-
Ashburner BP, Westerheide SD, Baldwin AS Jr, (2001) The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 21: 7065-7077.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7065-7077
-
-
Ashburner, B.P.1
Westerheide, S.D.2
Baldwin Jr., A.S.3
-
23
-
-
0036203419
-
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
-
Zhong H, May MJ, Jimi E, Ghosh S, (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9: 625-636.
-
(2002)
Mol Cell
, vol.9
, pp. 625-636
-
-
Zhong, H.1
May, M.J.2
Jimi, E.3
Ghosh, S.4
-
24
-
-
0141884374
-
Regulation of microglial inflammatory response by histone deacetylase inhibitors
-
Suuronen T, Huuskonen J, Pihlaja R, Kyrylenko S, Salminen A, (2003) Regulation of microglial inflammatory response by histone deacetylase inhibitors. J Neurochem 87: 407-416.
-
(2003)
J Neurochem
, vol.87
, pp. 407-416
-
-
Suuronen, T.1
Huuskonen, J.2
Pihlaja, R.3
Kyrylenko, S.4
Salminen, A.5
-
25
-
-
2342423022
-
In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
-
Miao F, Gonzalo IG, Lanting L, Natarajan R, (2004) In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J Biol Chem 279: 18091-18097.
-
(2004)
J Biol Chem
, vol.279
, pp. 18091-18097
-
-
Miao, F.1
Gonzalo, I.G.2
Lanting, L.3
Natarajan, R.4
-
26
-
-
31344446119
-
Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression
-
Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, et al. (2006) Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression. J Exp Med 203: 7-13.
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
Cosio, B.4
Ito, M.5
-
27
-
-
0036067845
-
Histone Deacetylases Augment Cytokine Induction of the iNOS Gene
-
Yu Z, (2002) Histone Deacetylases Augment Cytokine Induction of the iNOS Gene. J Am Soc Nephrol 13: 2009-2017.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2009-2017
-
-
Yu, Z.1
-
28
-
-
33244483352
-
OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis
-
Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Park C, et al. (2006) OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J Lipid Res 47: 450-460.
-
(2006)
J Lipid Res
, vol.47
, pp. 450-460
-
-
Wolins, N.E.1
Quaynor, B.K.2
Skinner, J.R.3
Tzekov, A.4
Park, C.5
-
29
-
-
78649403533
-
Differential regulation of Toll-like receptor signalling in spleen and Peyer's patch dendritic cells
-
Davies JM, MacSharry J, Shanahan F, (2010) Differential regulation of Toll-like receptor signalling in spleen and Peyer's patch dendritic cells. Immunology 131: 438-448.
-
(2010)
Immunology
, vol.131
, pp. 438-448
-
-
Davies, J.M.1
MacSharry, J.2
Shanahan, F.3
-
30
-
-
46149101224
-
Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes
-
Gonzales AM, Orlando RA, (2008) Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes. Nutr Metab (Lond) 5: 17.
-
(2008)
Nutr Metab (Lond)
, vol.5
, pp. 17
-
-
Gonzales, A.M.1
Orlando, R.A.2
-
31
-
-
64549155244
-
Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells
-
Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, et al. (2009) Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells. J Ethnopharmacol 123: 97-105.
-
(2009)
J Ethnopharmacol
, vol.123
, pp. 97-105
-
-
Tao, J.Y.1
Zheng, G.H.2
Zhao, L.3
Wu, J.G.4
Zhang, X.Y.5
-
32
-
-
49149090027
-
Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury
-
Rhinn H, Marchand-Leroux C, Croci N, Plotkine M, Scherman D, et al. (2008) Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury. BMC Mol Biol 9: 62.
-
(2008)
BMC Mol Biol
, vol.9
, pp. 62
-
-
Rhinn, H.1
Marchand-Leroux, C.2
Croci, N.3
Plotkine, M.4
Scherman, D.5
-
33
-
-
70349276663
-
Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide
-
Hirasawa N, Yashima K, Ishihara K, (2009) Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide. Life Sci 85: 578-585.
-
(2009)
Life Sci
, vol.85
, pp. 578-585
-
-
Hirasawa, N.1
Yashima, K.2
Ishihara, K.3
-
34
-
-
0037443478
-
CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP
-
Baccam M, Woo SY, Vinson C, Bishop GA, (2003) CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP. J Immunol 170: 3099-3108.
-
(2003)
J Immunol
, vol.170
, pp. 3099-3108
-
-
Baccam, M.1
Woo, S.Y.2
Vinson, C.3
Bishop, G.A.4
-
35
-
-
33745744362
-
TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications
-
Zampetaki A, Xiao Q, Zeng L, Hu Y, Xu Q, (2006) TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Biochem Biophys Res Commun 347: 89-99.
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 89-99
-
-
Zampetaki, A.1
Xiao, Q.2
Zeng, L.3
Hu, Y.4
Xu, Q.5
-
36
-
-
77951583810
-
Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis
-
Takahashi K, Sugi Y, Hosono A, Kaminogawa S, (2009) Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis. J Immunol 183: 6522-6529.
-
(2009)
J Immunol
, vol.183
, pp. 6522-6529
-
-
Takahashi, K.1
Sugi, Y.2
Hosono, A.3
Kaminogawa, S.4
-
37
-
-
77955575802
-
The role of p38 MAPK in valproic acid induced microglia apoptosis
-
Xie N, Wang C, Lin Y, Li H, Chen L, et al. (2010) The role of p38 MAPK in valproic acid induced microglia apoptosis. Neurosci Lett 482: 51-56.
-
(2010)
Neurosci Lett
, vol.482
, pp. 51-56
-
-
Xie, N.1
Wang, C.2
Lin, Y.3
Li, H.4
Chen, L.5
-
38
-
-
79961014004
-
Valproic acid exhibits biphasic effects on apoptotic cell death of activated lymphocytes through differential modulation of multiple signaling pathways
-
Chen Q, Ouyang DY, Geng M, Xu LH, Zhang YT, et al. (2011) Valproic acid exhibits biphasic effects on apoptotic cell death of activated lymphocytes through differential modulation of multiple signaling pathways. J Immunotoxicol 8: 210-218.
-
(2011)
J Immunotoxicol
, vol.8
, pp. 210-218
-
-
Chen, Q.1
Ouyang, D.Y.2
Geng, M.3
Xu, L.H.4
Zhang, Y.T.5
-
39
-
-
0035979737
-
Duration of nuclear NF-kappaB action regulated by reversible acetylation
-
Chen L, Fischle W, Verdin E, Greene WC, (2001) Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science 293: 1653-1657.
-
(2001)
Science
, vol.293
, pp. 1653-1657
-
-
Chen, L.1
Fischle, W.2
Verdin, E.3
Greene, W.C.4
-
40
-
-
0037011056
-
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
-
Chen LF, Mu Y, Greene WC, (2002) Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. EMBO J 21: 6539-6548.
-
(2002)
EMBO J
, vol.21
, pp. 6539-6548
-
-
Chen, L.F.1
Mu, Y.2
Greene, W.C.3
-
41
-
-
2342522110
-
Shaping the nuclear action of NF-kappaB
-
Chen LF, Greene WC, (2004) Shaping the nuclear action of NF-kappaB. Nat Rev Mol Cell Biol 5: 392-401.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 392-401
-
-
Chen, L.F.1
Greene, W.C.2
-
42
-
-
79958189845
-
Histone acetyltransferases are crucial regulators in NF-kappaB mediated inflammation
-
Ghizzoni M, Haisma HJ, Maarsingh H, Dekker FJ, (2011) Histone acetyltransferases are crucial regulators in NF-kappaB mediated inflammation. Drug Discov Today 16: 504-511.
-
(2011)
Drug Discov Today
, vol.16
, pp. 504-511
-
-
Ghizzoni, M.1
Haisma, H.J.2
Maarsingh, H.3
Dekker, F.J.4
-
43
-
-
0033555787
-
Nuclear factor-kappa B p65 mediates the assembly and activation of the TNF-responsive element of the murine monocyte chemoattractant-1 gene
-
Ping D, Boekhoudt GH, Rogers EM, Boss JM, (1999) Nuclear factor-kappa B p65 mediates the assembly and activation of the TNF-responsive element of the murine monocyte chemoattractant-1 gene. J Immunol 162: 727-734.
-
(1999)
J Immunol
, vol.162
, pp. 727-734
-
-
Ping, D.1
Boekhoudt, G.H.2
Rogers, E.M.3
Boss, J.M.4
-
44
-
-
77957917520
-
Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line
-
Waby JS, Chirakkal H, Yu C, Griffiths GJ, Benson RS, et al. (2010) Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line. Mol Cancer 9: 275.
-
(2010)
Mol Cancer
, vol.9
, pp. 275
-
-
Waby, J.S.1
Chirakkal, H.2
Yu, C.3
Griffiths, G.J.4
Benson, R.S.5
-
45
-
-
0028048369
-
Generation of lymphohematopoietic cells from embryonic stem cells in culture
-
Nakano T, Kodama H, Honjo T, (1994) Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science 265: 1098-1101.
-
(1994)
Science
, vol.265
, pp. 1098-1101
-
-
Nakano, T.1
Kodama, H.2
Honjo, T.3
-
46
-
-
0034214246
-
Transcriptional regulation of adipogenesis
-
Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM, (2000) Transcriptional regulation of adipogenesis. Genes Dev 14: 1293-1307.
-
(2000)
Genes Dev
, vol.14
, pp. 1293-1307
-
-
Rosen, E.D.1
Walkey, C.J.2
Puigserver, P.3
Spiegelman, B.M.4
-
47
-
-
0028180070
-
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer
-
Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM, (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8: 1224-1234.
-
(1994)
Genes Dev
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
48
-
-
20444471451
-
Secretory factors from human adipose tissue and their functional role
-
Hauner H, (2005) Secretory factors from human adipose tissue and their functional role. Proc Nutr Soc 64: 163-169.
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 163-169
-
-
Hauner, H.1
-
49
-
-
0031762908
-
Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid
-
Fried SK, Bunkin DA, Greenberg AS, (1998) Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 83: 847-850.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 847-850
-
-
Fried, S.K.1
Bunkin, D.A.2
Greenberg, A.S.3
-
50
-
-
4744361664
-
Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice
-
Harkins JM, Moustaid-Moussa N, Chung YJ, Penner KM, Pestka JJ, et al. (2004) Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice. J Nutr 134: 2673-2677.
-
(2004)
J Nutr
, vol.134
, pp. 2673-2677
-
-
Harkins, J.M.1
Moustaid-Moussa, N.2
Chung, Y.J.3
Penner, K.M.4
Pestka, J.J.5
-
51
-
-
33751235259
-
Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes
-
Chung S, Lapoint K, Martinez K, Kennedy A, Boysen Sandberg M, et al. (2006) Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. Endocrinology 147: 5340-5351.
-
(2006)
Endocrinology
, vol.147
, pp. 5340-5351
-
-
Chung, S.1
Lapoint, K.2
Martinez, K.3
Kennedy, A.4
Boysen Sandberg, M.5
-
52
-
-
84857233842
-
Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay
-
Grabiec AM, Korchynskyi O, Tak PP, Reedquist KA, (2012) Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay. Ann Rheum Dis 71: 424-431.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 424-431
-
-
Grabiec, A.M.1
Korchynskyi, O.2
Tak, P.P.3
Reedquist, K.A.4
-
53
-
-
57349114027
-
Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
-
Choi Y, Park SK, Kim HM, Kang JS, Yoon YD, et al. (2008) Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model. Exp Mol Med 40: 574-581.
-
(2008)
Exp Mol Med
, vol.40
, pp. 574-581
-
-
Choi, Y.1
Park, S.K.2
Kim, H.M.3
Kang, J.S.4
Yoon, Y.D.5
-
54
-
-
79954842538
-
Histone deacetylase inhibitors block nuclear factor-kappaB-dependent transcription by interfering with RNA polymerase II recruitment
-
Furumai R, Ito A, Ogawa K, Maeda S, Saito A, et al. (2011) Histone deacetylase inhibitors block nuclear factor-kappaB-dependent transcription by interfering with RNA polymerase II recruitment. Cancer Sci 102: 1081-1087.
-
(2011)
Cancer Sci
, vol.102
, pp. 1081-1087
-
-
Furumai, R.1
Ito, A.2
Ogawa, K.3
Maeda, S.4
Saito, A.5
-
55
-
-
57349101675
-
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
-
Sabio G, Das M, Mora A, Zhang Z, Jun JY, et al. (2008) A stress signaling pathway in adipose tissue regulates hepatic insulin resistance. Science 322: 1539-1543.
-
(2008)
Science
, vol.322
, pp. 1539-1543
-
-
Sabio, G.1
Das, M.2
Mora, A.3
Zhang, Z.4
Jun, J.Y.5
-
56
-
-
84855430348
-
PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue
-
Matsubara T, Mita A, Minami K, Hosooka T, Kitazawa S, et al. (2012) PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue. Cell Metab 15: 38-50.
-
(2012)
Cell Metab
, vol.15
, pp. 38-50
-
-
Matsubara, T.1
Mita, A.2
Minami, K.3
Hosooka, T.4
Kitazawa, S.5
-
57
-
-
55949119252
-
Muscle as an endocrine organ: focus on muscle-derived interleukin-6
-
Pedersen BK, Febbraio MA, (2008) Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol Rev 88: 1379-1406.
-
(2008)
Physiol Rev
, vol.88
, pp. 1379-1406
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
58
-
-
79953765855
-
Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway
-
Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, et al. (2011) Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab 13: 401-412.
-
(2011)
Cell Metab
, vol.13
, pp. 401-412
-
-
Awazawa, M.1
Ueki, K.2
Inabe, K.3
Yamauchi, T.4
Kubota, N.5
-
59
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
Ellingsgaard H, Hauselmann I, Schuler B, Habib AM, Baggio LL, et al. (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med 17: 1481-1489.
-
(2011)
Nat Med
, vol.17
, pp. 1481-1489
-
-
Ellingsgaard, H.1
Hauselmann, I.2
Schuler, B.3
Habib, A.M.4
Baggio, L.L.5
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